월남전 당시 살포된 고엽제에 의해 발생한 것으로 생각되는 피부 질환

이증훈,김윤동,서기범,박장규 충남대학교 의학연구소 2001 충남의대잡지 Vol.28 No.2

Although many dermatologists need adequate information about Agent Orange-related skin lesions, there have been few researches about them. We observed various skin manisfestations from 266 Korean Vietnam veterans who visited Department of Dermatology, Chungnam National University Hospital, inculding seborrheic dermatitis(46%), xerotic eczema(45%), chloracne(30%), generalized pruritus (10%), dermographism (5%), chronic urticaria (4%), photosensitive dermatitis (3%), etc. Among them chloracne is well known as a disease which results from exposure to Agent Orange which was used for a defoliating agent during Vietnam war. It is a refractory acneiform eruption due to halogenated polyaromatic compounds(eg. dioxin, dibenzofurane, polychlorinated biphenyls, etc.). 2,3,7,8-tetrachlorodibenzo-p-dioxin, a kind of dioxin isomer, contained in the Agent Orange which was used for a defoliating agent during Vietnam war. It is characterized by recalcitrant comedones and cysts predominantly in the malar and postauricular area. We concluded that the various skin lesions in Vietnam veterans resulted from probably the chemicals in defoliant and further researches would be required to find out subjective guidelines for the evaluation of the skin lesions.

자유곡선을 포함한 다중형상에서의 Exit Burr 판별 프로그램 개발

이장범,김영진 한국경영과학회 2003 한국경영과학회 학술대회논문집 Vol.- No.1(1)

Milling 가공시 공구와 피삭재의 접합면에서는 절삭가공의 잔유물인 Burr가 생성되고, 이러한 Burr는 작업효율과 정밀도를 감소시키며 후처리과정(Deburring)을 야기시키는 원인이 된다. 그러므로 정밀도와 작업효율을 극대화하기 위해서는 이러한 Burr의 생성원리를 파악함과 동시에 Exit Burr의 여부에 대한 판별을 하여 최적의 가공조건을 맞추어주어야 하는데, 이러한 경우에 지금까지는 점, 선 및 원으로 피삭재의 형상을 재현하여 공구의 경로와의 Exit 각을 통해 결과를 예측하는 연구를 해왔었다. 본 논문에서 추구하고자 하는 핵심은 이러한 피삭재의 형상을 재현하기 위해 지금까지 사용해왔던 요소를 보다 다양화시키는 방안을 제시하여 프로그램의 적용 범위를 넓히려는 것이다. 예컨대 이제까지 실제 가공에서 사용되고 있는 임의형상에 대한 표현 방식 중에서 대다수 CAD 프로그램에서 곡선 및 곡면을 표현하는 경우, B-Spline Curve의 알고리즘은 패삭재의 불규칙적인 곡면을 가장 근사하게 표현하는 최적의 해결책으로 쓰여지고 있다. 그러므로 이러한 알고리즘을 통해 프로그램의 적용 예를 넓히는 것은 보다 다양한 조건에서의 Burr 생성에 대한 예측을 가능케 해주는 것이다. 본 논문에서는 앞에서 언급한 바와 같이 B-Spline Curve 알고리즘을 개발하고, 프로그램에 적용하는 일련의 과정을 통해 보다 다양한 형상의 피삭재에서 단일 혹은 복합경로의 공구가 지나갈 경우에 생길 수 있는 Burr를 얼마나 효율적으로 판별할 수 있는지를 소개하고자 한다.

층수돌기 방선균증 : 1예 보고

이범하,이혜경,박성진,차장규,김희경 순천향대학교 의학연구소 2008 Journal of Soonchunhyang Medical Science Vol.14 No.2S

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고기능성 미립 실리카 제조

이재장,노범식,김동수,장광택 강원대학교 부설 석재복합신소재 제품연구센터 2000 석재연 논문집 Vol.5 No.-

본 연구에서는 attrition mill을 활용하여 분쇄시 발생하는 오염물질을 방지하고 고분자 유기물질의 첨가로 평균 입도 2-3㎛의 미립 실리카 분체에 가능성을 부여하여 규석 관련 첨단산업용 고부가가치 상품을 개발하고자 하였다. 실험결과 용기 내부의 코팅재에 따른 미립화 효율은 세라믹 > 텅스텐 카바이드 > 스테인레스 > 포리우레탄 > 테프론의 순이었으며 오염방지 효과는 세라믹 > 폴리우레탄 > 텅스텐 카바이드 > 테프론 > 스테인레스의 순이었다. 고분자 유기물질의 첨가에 의해 분쇄효율이 증가하였으며, 첨가제의 일부가 표면에 코팅되어 원관의 백색도 85에서 92까지 상승되었다. 형상 조절 실험 및 백색도 향상 실험결과 첨가에에 의한 분쇄 산물은 원광보다 구형에 가까운 것을 알 수가 있었다. This study focused on manufacture of the high value-added products for a high-technology industry related to silica. The silica fines less than 3㎛ was manufactured using laboratory attrition mills with various coated liner and analysed the pollutions added from the grinding test. Ground particle's shape was investigated by adding polymer. In the grinding test, coated material of cylinder affects size reduction rate by order of ceramic, tungsten carbide, stainless steel, polyurethane, teflon. In contamination tests the coated liner affects in order of stainless steel, teflon, tungsten carbide, polyurethane, ceramic. It was found also that the result of additive test showed an instant effects of grinding and whiteness.

주물사 부산물의 정제에 관한 연구

이재장,노범식,문영배 강원대학교 석재복합신소재제품연구센터 2001 석재연 논문집 Vol.6 No.-

연구에서는 주물사용 규석의 생산과정에서 발생되는 부산물인 미립 분말의 부가가치를 향상시킬 수 있는 기술개발을 통하여 자원의 절약과 재활용은 물론이고, 환경오염 문제의 해결에도 기여하고자 하였다. 성분분석 결과 입자 크기가 큰 경우에는 SiO2의 함량이 낮고 다른 불순물의 함량이 많았으며, 부산물의 경우는 SiO2의 함량이 94.37%로 비교적 낮고 Fe2O3, Al2O3 및 K2O의 함량이 상대적으로 높았다. XRD 분석 결과 석영 이외에 백운모가 상당량 포함되어 있어 품위 및 회수율 향상에 영향을 미칠 것으로 생각되어 이를 효과적으로 제거 할 수 있는 자력선발과 비중선별을 이용하였다. 자력선별 실험결과 부산물(tailing)의 경우 SiO2 품위와 산출률은 각각 98.42%와 87.35%까지 향상되었으며 Fe2O3의 함량은 0.17%이었다. 비중선별 결과 SiO2 품위와 산출률은 각각 96.08%와 91.16%까지 향상되었으며 Fe2O3의 함량은 0.30%로 자력선별의 경우보다 효율이 좋지 않았다. 부산물(tailing)을 대상으로 Attrition Mill로 알루미나 볼과 스테인레스 볼을 Grinding media로 이용하여 60min 정도 분쇄한 결과 평균입도 2~3㎛ 정도의 미립 실리카 분체를 제조할 수 있었다. Representative samples of solid molding sand wastes were obtained from Kwang-Jin Industrial Co. located in Chunchon. The molding sand wastes contains mainly fine iron particles, iron oxides and mica group minerals. Sand grains are angular because of being produced by the impact crushers. This study was carried out to develop an effective and economic purification technique for removing iron minerals by using magnetic separator and Mozley table. Results of experiment using the magnetic separator showed the production ratio of SiO2 increased up to 98.42wt.% and 87.35wt.% and the amount of content of Fe2O3 was 0.17wt.%. and those using the Mozley table separator showed SiO2 up to 96.08wt.% and Fe2O3 was 0.30wt.%, respectively. In grinding tests, silica flour of mean size 2~3㎛ was produced using attrition mill by stainless ball and alumina ball grinding about 60 minutes.

대전에서 연중 태양광선의 UVA와 UVB양에 대한 조사 (예비보고)

박장규,김경훈,이우재,서기범 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

Ultraviolet A(355 nm) and ultraviolet B(290 nm) doses were measured at Taejon from March to September, 1993, on four different weather conditions(clear, relatively clear, relatively cloudy and cloudy). And the results were compared with the doses of Kongju area measured in 1985. The followings were the summary of the findings. 1. UVA(1.98± 0.35 × 10 exp(-3) w/㎠) and UVB(17.62+ 5.72 X 10 exp(-6) w/㎠ doses were peak at noon on clear weather. 2. Average doses of UVA(2.36±0.70 × exp(-3) w/㎠) and UVB(24.28±8.83 × exp(-3) w/㎠) were peak at noon in August on clear weather. 3. The doses of UVA and UVB were influenced by yellow sand, fog and other pollutants. 4. The doses of UVA on clear weather in Daejoen were lower than Kongju about 40%, in contrast those of UVB were not different in statistical values.

강릉 옥계지역 田자집의 공간구성 변화실태와 효과적인 개량방법 모색에 관한 연구

최장순,이상범 대한건축학회 2004 대한건축학회논문집 Vol.20 No.10

The two villages, Jungchon and Shinchon, at Okgye in Gangneung area are consisted of 田-shaped houses in the past But the dwelling space of the 田-shaped houses was changed to pursue the convenience and function by the modernization policy of the government authorities The purpose of this study is aimed at grasping how the spatial transformations of 田-shaped houses by the modernization and urbanization have been coped with and changed. The results are as follows The maintenance or removal of wall, the fuel change of heating and cooking, the leveling change of kitchen floor and so on made possible the standing life. And its plan was changed from two row room which was made by climatic confrontation to one row room by removal of wall lying between front room and back room, the fuel change of heating, the change of heating method and the heat insulating material. The roof material was changed from the traditional roof material such as a rice straw, wood tile and the bark of an acorn tree to the modern roof material such as a corrugated sheet iron or corrugated asbestos-cement sheet. And the structure of cement brick or block was attached to the traditional wood structure because of the easiness of execution

자극성 물질이 첩포시험 결과에 미치는 영향에 대한 연구

박장규,이우재,김경훈,서기범,이증훈 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

We studied the effects of irritants on the positive patch test sites in 6 volunteers. We firstly performed the patch test with 2, 4, 6, 8, 10% sodium lauryl sulfate on the back of 22 volunteers. Allergens (thimerosal, mercury ammonium chloride) were applied in duplicate, and 24 hours later they were removed and sodium lauryl sulfate was applied for a further 24hours to one set of patches. Response of allergen alone were measured at 24 hours, 48 hours, 72 hours, 120hours, 140hours and the degree of inflammation of the other site(allergen + irritant) was graded 30 minutes, 24, 48 and 72 hours later according to International Contact Dermatitis Research Group. The results were as follows 1. Twenty volunteers(90.9%) showed irritation sign on the patch sites with 6% sodium lauryl sulfate. 2. In the results of patch test in 6 cases with positive allergen sites, 5 cases showed the similar results with those of previous patch test (reproducibility = 83 %) 3. When we assessed the patch test results according to ICDRG, the results of patch tests after application with irritants on previous positive allergen slites did not show stronger responses than those of positive allergen alone 4. The results of patch test after application with irritants on previous negative allergen did not show erythema. It seems that the effect irritant application of lower concentration than irritant dose not influence the response to the allergen concentration than to cause erythema, on the response of allergen

알레르기 피부 반응 검사시 판독 시간에 따른 팽진의 크기 변화

박장규,윤소영,이웅재,서기범,이증훈 충남대학교 의과대학 지역사회의학연구소 1996 충남의대잡지 Vol.23 No.2

There have been several positive criteria for skin prick test, which has been most commonly used in the diagnosis of allergic diseases. Among them, comparing wheal size induced by allergen to that induced by histamine is logical for criteria of skin prick test positivity. We measured the wheal sizes induced by histamine and various causative allergens with five minutes interval, from 5 minutes to 40 minutes, and compared of the time which the wheal size of both reached at peak. The followings were the summary of the findings. 1. Maximal sizes of wheals induced by histamine reached at 12 minutes in average. 2. Maximal sizes of wheals induced by allergens reached at 15 minutes in average. 3. There was no statistical difference between the time of maximal size of wheal induced by histamine and causative allergen.

백반증의 PUVA치료반응에 관한 연구(제1보)

박장규,성열훈,성범진,김영호,이증훈 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.2

The authors evaluated response to PUVA therapy in 44 vitiligo petients who did'nt show the spontaneous re-pigmentation. In the responded group to PUVA therapy after systemic administration of 8-methoxy psoralen, average MPD of female patients was 3.4 times higher than males, interestingly. Number of irradiation of UVA was similar between male and female, but total doses of female patients group were about 2 times than males till the first re-pigmented spots were noted. The response to PUVA therapy was quite different according to duration of disease and site of lesion. Therefore, we suppose that it is necessary to consider sex of patient, duration of disease, location of vitiligo before making a plan of PUVA therapy.