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치과 기공사들에게서 나타나는 호흡기 증상과 이의 관련 요인
김웅철,오세윤,김지환,김진완,이준석,이가영,이세훈,유진호,김태석 高麗大學校 倂設 保健大學 保健科學硏究所 2001 保健科學論集 Vol.27 No.1
This study was carried out to investigate subjective respiratory symptoms and their attributable factors in Korean dental laboratory technicians. A questionnaire was mailed to randomly selected 1,900 dental laboratory technicians. Among them, 1,344 dental technicians completed the questionnaires and returmned them. Validity and reliability tests on the questionnaires were carried out before the main survey. To investigate risk factors on respiratory subjective symptoms, we performed analysis on distribution of characteristics, and then investigated univariate analysis and multiple logistic regression analysis. The prevalence rate of wheezing, cough and phlegm, and dyspnea was 4.8%, 33.9%, 54.9%, respectively. Statistically significant factors inducing subjective respiratory symptoms by multiple logistic regression analysis were sex, smoking, exercise, health examination, work hours a day, investment gas, investment dust, metal fume, resin vapor, and asbestos dust. Considering the results above, it seems that most subjective respiratory symptoms are related with health habits and occupational environmental-related factors. The result, consideration in mind, suggest that health promotion programs for smoking cessation, regular health examination, and physical exercise in health habit, and improvement on casting and resin work in dental technological environment be necessary.
정철영,고재관,황원채,윤희철,박가열,김재호,이성식,김동승,표성일,이건남,양안나,최수정,김은석 한국직업능력개발원 2008 직업능력개발연구 Vol.11 No.1
이 연구의 목적은 제대군인에 대한 효율적인 전직지원을 위해서 현행 전직지원 프로세스에 대한 개선 안과 이에 따른 국방부, 국가보훈처 등 제대군인 전직지원관련 기관 간의 역할분담 및 연계방안에 대해서 제안하는 것이다. 연구는 크게 세 가지 과정을 거쳤다. 첫째, 국내 군 전직지원 실태를 분석하여 문제점과 시사점을 도출하였다. 둘째, 이러한 문제점과 시사점, 군 전직지원 선행연구를 종합하여 효율적인 군 전직지원 프로세스 안을 제시하였다. 셋째, 구축한 군 전직지원 프로세스 안에 따라 주요 군 전직지원 관련 기관인 국방부, 국가보훈처의 역할 분담 안을 제안하였다. This study aims to suggest an improvement plan for the support process of effective occupation change for discharged soldiers and then role assignments among related institutions for supporting discharged soldiers such as Ministry of Defense, Ministry of Patriots and Veterans Affairs, Ministry of Labor and the cooperation plan among the institutions. The study was made in three steps. First, after analyzing currents support facts and status for discharged soldiers, it induced its problems and implications. Second, integrating the findings of previous studies related to support plan on occupation changes for the discharged soldiers, Problems and implications mentioned above, it constructed effective occupation change process for discharged soldiers. Then, according to the established process, it suggested role assignments such as Ministry of Defense, Ministry of Patriots and Veterans Affairs, Ministry of Labor.
Lee, Ji-Ho,Bae, Yoon Ju,Lee, So-Hee,Kim, Su-Chin,Lee, Hyun-Young,Ban, Ga-Young,Shin, Yoo Seob,Park, Hae-Sim,Kratzsch, Juergen,Ye, Young-Min The Korean Academy of Asthma, Allergy and Clinical 2019 Allergy, Asthma & Immunology Research Vol.11 No.1
<P><B>Purpose</B></P><P>Frequent changes in chronic urticaria (CU) activity over time can cause psychological stress, which also serves as a trigger of CU. To measure the control status of CU, the Urticaria Control Test (UCT) was developed in Germany. This study aimed to investigate the validity, reliability and responsiveness to changes in CU for the Korean version of the UCT (K-UCT) and its relation with salivary cortisol and cortisone levels.</P><P><B>Methods</B></P><P>Linguistic adaptation of the UCT into Korean was conducted. A total of 96 CU patients were enrolled, and 80 of them completed the study. The K-UCT and other outcome scores for CU were measured and repeated after 4 weeks of treatment. Control status was classified by physicians into well-controlled, partly-controlled, and uncontrolled CU. Salivary cortisol and cortisone were measured by liquid chromatography-tandem mass spectrometry.</P><P><B>Results</B></P><P>Excellent internal consistency and intra-class reliability were obtained. Strong correlations between the K-UCT and disease severity, reflected in the Urticaria Activity Score (UAS)/global assessment of urticaria control by physicians/patient assessment of symptom severity/CU-specific quality of life were noted. K-UCT scores ≥12 were found to be optimal for determining well-controlled CU (sensitivity, 75.0%; specificity, 758%; area under the curve, 0.824). Perceived stress scale scores were significantly correlated with the UAS and the K-UCT. Salivary cortisone levels were significantly correlated with K-UCT (<I>r</I> = 0.308, <I>P</I> = 0.009) and differed significantly according to control status determined by a K-UCT ≥12.</P><P><B>Conclusions</B></P><P>This study demonstrated that the K-UCT can be a valid instrument with which to gauge CU control status in Korean patients. Further studies are needed to validate salivary cortisone as a biomarker for CU control.</P>
( Ga Young Lee ),( Sukki Cho ),( Jin-haeng Chung ),( Hyung-jun Kim ),( Myung Jin Song ),( Byung Soo Kwon ),( Sung Yoon Lim ),( Yeon-joo Lee ),( Jong Sun Park ),( Young-jae Cho ),( Ho Il Yoon ),( Jae H 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.-
Background Spread through air spaces (STAS) is a recently determined pathologic phenomenon of lung cancers with significant impact on prognosis. However, the possible influence of mechanical forces caused by diagnostic interventions on the occurrence of STAS has not yet been explored. The purpose of this study was to evaluate the association of diagnostic lung biopsy on the risk of STAS, and its prognostic impact in resected stage I NSCLC. Methods We performed a retrospective review of 2,238 patients who underwent surgery for stage I NSCLC, from January 2011 to December 2019 in Seoul National University Bundang Hospital. The risk factors for STAS was assessed by logistic regression. In addition, the association between previous diagnostic lung biopsy and incidence of recurrence, lung cancer-related mortality were assessed stratified by STAS positivity with Multivariate Cox’s regression analyses and the Kaplan-Meier method. Results Of the 2,238 patients analyzed, 677(30.2%) patients had positive STAS. Lung cancer with STAS tended to be solid tumors with greater tumor size and T stage. In the univariate logistic regression analysis for the risk of STAS, previous percutaneous needle biopsy (OR=1.81, P<0.001), bronchoscopic biopsy (OR=1.42, P<0.030), bronchoscopic washing and BAL(OR=1.41, P<0.005) were all significantly associated with the risk for STAS. However, in the multivariate analysis, only solid type(OR=2.54,P<0.001) and tumor size (OR=1.76, P<0.001) remained significant for STAS positivity. Multivariate Cox proportional hazards models showed that after adjustments for previous diagnostic procedures, STAS was a significant risk factor for cancer recurrence(OR=1.62, P=0.005). In addition, for STAS positive patients, sublobar resection remained a significant risk factor for recurrence(OR=2.93, P<0.001) and lung cancer related mortality(OR= 9.58, P<0.001) after adjustments for previous diagnostic procedures. Conclusions Previous lung biopsy and intervention in stage I NSCLC are not associated with the development of STAS, and do not affect the prognosis of NSCLC related to STAS.
Effects of Herbal treatment for In-patients with Mild Fever: Retrospective Clinical Study
Lee, Sun-Ju,Han, In-Sik,Oh, Hyun-Suk,Lee, Dong-Jin,Yoon, Jeung-Won,Choi, Ga-Young,Hong, Sun-Gi,Lee, Won-Chul,Sun, Seung-Ho The Society of Korean Medicine 2011 대한한의학회지 Vol.32 No.6
Objectives: This study was designed to investigate the effect of herbal extract medicines for inpatients with fever symptoms in an oriental medicine hospital. Methods: Medical records of inpatients who experienced over $38^{\circ}C$ of fever from July 2010 to August 2011 has been requested with deleted personal identifiable information. The requested data were analyzed by patients' general characteristics, administrated western/herbal medicines, and changes in the body temperature of four administration groups (group 1, herbal extract medicine only; group 2, western medication(antibiotics/antipyretics) only; group 3, combination of herbal extract medicine and western medication; group 4, no medication control). The SPSS 19.0 was used for statistical analysis and p-value of less than 0.05 was regarded significant. Results: The body temperature has significantly dropped over time in the herbal extract medicine only group (p<0.001) along with the antibiotics/antipyretics only group. When both treatments were combined, stronger antipyretic effect was shown compared to the sole treatment of herbal extract medicine or antibiotics/antipyretics. Conclusion: The use of herbal extract medicines may be effective in alleviation of fever.
Lee, Ga Young,Park, Chan Yoon,Cha, Kyeong Sun,Lee, Seung Eun,Pae, Munkyong,Han, Sung Nim Elsevier 2018 The Journal of nutritional biochemistry Vol.55 No.-
<P>Vitamin D has an immunoregulatory effect on both innate and adaptive immunity. Contradictory results regarding vitamin D and natural killer (NK) cell functions have been reported with in vitro studies, but little is known about this in vivo. We investigated whether vitamin D levels (50, 1000 or 10,000 IU/kg of diet: DD, DC or DS) affect NK cell functions in mice fed a control or high-fat diet (10% or 45% kcal fat: CD or HFD) for 12 weeks. The splenic NK cell activity was significantly higher in the CD-DS group than the HFD-DS group, and the CD-DS group showed significantly higher NK cell activity compared with the CD-DD and CD-DC groups. However, no difference in NK cell activity was observed among the HFD groups fed different levels of vitamin D. The splenic population of NK cells was significantly higher in the CD-DS group than the HFD-DS group. There was no difference in the intracellular expression of IFN-gamma and the surface expression of NKG2D and CD107a in NK cells by both dietary fat and vitamin D content. The splenic mRNA expression of Ifng and CcI5 was significantly lower in the HFD groups compared with the CD groups, but there was no difference in the mRNA levels of Vdup I and Vdr among the groups. Taken together, these results suggest that dietary vitamin D supplementation can modulate innate immunity by increasing NK activity in control mice but not in obese mice. This effect might be mediated through alternation of the splenic NK cell population. (C) 2018 Elsevier Inc. All rights reserved.</P>