전침 자극에 의한 오디 괄약근 운동성 변화에 관한 연구

이성구,김명완,김홍자,서동환,이상수,김동일,유교상,주연호,민병일,김지훈 경희대학교 동서의학연구소 2001 東西醫學硏究所 論文集 Vol.2000 No.-

Background/Aims: This study was designed to evaluated the effects of electroacupuncture on the sphincter of Oddi (SO) motility in humans and to correlate the manometric findings with plasma cholecystokinin (CCK) levels. Methods: Eleven patients (M: F= 5: 6) who had various kinds of biliary disorders were enrolled. SO motility was monitored with a conventional low-compliant continuously perfused technique using ERCP (n=9) or percutaneous transhepatic cholangioscope (n=2). After baseline monitoring for phasic wave contractions of SO, electroacupuncture was applied at a specific acupoint, GB 34, in these 11 patients. A nonspecific acupoint 5 cm away from GB 34 was selected as a control. Manometric parameters of SO were also checked in 6 subjects during stimulation of the control acupoint. CCK plasma levels were measured during the time course of electroacupuncture stimulation. Result: All the manometric parameters including the basal pressure of SO, amplitude, frequency and duration of phasic wave contraction of SO were significantly decreased (p< 0.05) during electroacupuncture stimulation. The inhibition of SO contractility was accompanied by increased CCK plasma levels. After removal of electroacupuncture stimulation, restoration of amplitude and duration to basal condition were noted. A tendency towards the return of SO contractility was also observed in basal pressure and frequency. Stimulation of the control acupoint, however, did not affect the SO contractility and plasma CCK levels. Conclusions: Electroacupuncture stimulation of acupoint GB 34 showed reversible inhibition of SO contraction in humans. We speculate that the response of SO to electroacupuncture stimulation may be mediated by some neurohormonal mechanisms including CCK release. (Korean Journal of Gastrointestinal Motility 2000;6:44-41)

보건관리 대행사업 평가도구의 타당성, 신뢰도 및 인과관계 검증에 관한 연구

박정일,조병희,구정완,김광종,김현욱,원종욱,이명숙,정문희 가톨릭대학교 산업의학센터 2001 韓國의 産業醫學 Vol.40 No.1

In order to verify the validity, reliability and relativeness of preliminary evaluation tool for the group occupational health services(GOHS), a questionnaire survey for doctors, nurses and hygienists of 18 GOSH institutions, and employers, health managers and employees of 340 enterprises was conducted. A factor analysis and correlation test for the statistical validity of the variables in the evaluation tool, a Chronbach's Alpha value for the reliability in the evaluation indices and a regression analysis for the relations of the evaluation model were performed. The results were as follows: 1.In factor analysis, thirty-three variables among 43 variables were selected as significant variables, ie 9 out of 11 for input index, 11 out of 14 for throughout index and 13 out of 18 for out put index. 2.Three evaluation(outcome) scales(evaluation by employer, health manager and employee) which composed of 16 identical items were used. 3.The Chronbach's Alpha values of input, throughout, out put and outcome indices were 0.5221, 0.5473, 0.7122 and 0.8546 respectively. 4.Regression equations of independent variables on the evaluation scales of employer, health manager and employee were all statistically significant.

쇼그렌 증후군을 동반한 자가 면역성 만성 췌장염 1예

김순주,김명환,이상수,송문희,이성구,서동완,민영일 대한내과학회 2004 대한내과학회지 Vol.66 No.4

저자 등은 쇼그렌 증후군을 동반한 자가 면역성 만성 췌장염 증례를 국내 최초로 보고하면서 스테로이드 경구 복용 후에 자가 면역성 만성 췌장염 뿐만 아니라 쇼그렌 증후군의 임상양상도 호전되었다는 점에서 매우 의미있는 증례로 판단하여 문헌고찰과 함께 본 증례를 보고한다. We report a case of autoimmune chronic pancreatitis associated with Sjogren's syndrome. A68-year-old man was admitted to the hospital with jaundice. The serum IgG and IgE were elevated and endoscopic retrograde cholangipancreatography demonstrated an irregular narrowing of the main pancreatic duct and stricture of the distal common bile duct. He complained of dry mouth and dry eyes with a gritty feeling. On physical examination, enlargement of both submandibular glands was noted. Schirmer test revealed positive result and the labial minor salivary gland biopsy showed infiltration of lymphocytes and plasma cells, consistent with Sjogren's syndrome. After one month of oral steroid therapy, the abnormalities in clinical, laboratory and radiological findings of autoimmune chronic pancreatitis were improved markedly. The enlargement of both submandibular glands was improved, too. To our knowledge, this is the first case of autoimmune chronic pancreatitis associated with Sjogren's syndrome in Korea.

보건관리 대행사업 평가 지표 및 척도개발에 관한 연구

박정일,조병희,구정완,김광종,김현욱,원종욱,이명숙,이원철,정문희 가톨릭대학교 산업의학센터 2000 韓國의 産業醫學 Vol.39 No.3

This study was carried out to develop the index and the scales for the evaluation of the group occupational health services(GOHS). The possible variables of each step, firstly, based on an evaluation model composed of four steps, input, throughout, output and outcome, were selected through several meetings of professional committee. And five types of questionnaire(for doctor, nurse, industrial hygienist, employer, and employee) were developed based on the selected variables. A pilot survey for four GOHS institutions and 12 enterprises was conducted using the questionnaires and correlation analysis for extracting variables was done. The results were as follows: 1.The evaluation scale was composed of three areas(evaluation on workers' health and work environment, evaluation by institution and employer, and evaluation by employee)which were devided into ten subscales. 2.Among firstly selected ninety-six variables, forty-three variables (11 for input, 14 for throughout, and 18 for output indices) were extracted by correlation analysis. 3.Based on the extracted variables, the questionnaires were simplified as five items for doctor, thirty-six items for nurse, nine items for industrial hygienist, and twenty-six items for employer and employee. 4.The total score of evaluation model was defined on the basis of four-hundred points as sum of four indices (input, throughout, output and outcome) given one-hundred points each.

Effects of Panax ginseng on the Adverse Actions Induced by Abuse Drugs

Ki Wan Oh, Myung Koo Lee, Jin Tae Hong 충북대학교 약품자원개발연구소 2005 약학논문집 Vol.20 No.-

-본문참고-

중소규모 제조업체 근로자의 인구·사회학적 특성이 건강행동변화단계에 미치는 영향

구명회,임현우,박정일,이강숙,구정완 大韓産業醫學會 2002 대한직업환경의학회지 Vol.14 No.1

목 적 : 근로자 건강증진을 위한 사업장 건강증진 사업 프로그램 기획실에 건강 위험요인을 평가하고 근로자 특성에 4따른 행동변화단계를 조사하여 행동 변화단계에 따른 성공적인 근로자 건강증진전력을 위한 기초자료를 제공하고자 본 연구를 진행하였다. 방 법 : 경인지역이 중소 기업 제조업체 근로자 282명을 대상으로 설문조사를 수행하였으며, 일반적 특성에 대한 조사, 건강위험평가, 위험요인에 대한 행동변화단계를 조사하였다. 결 과 : 건강위험평가에서 흡연자는 남자 근로자에 서 65.7 %, 규칙적인 운동을 하지 않는 남자 근로자는 70.5 %, 여자 근로자는 86.1 %이었고 음주는 남자 근로자의 78.6 %, 여자 근로자인 50 %이었고 과음은 남자 근로자의 29.5 %, 여자 근로자의 11.1 %이었다. 건강한 생활습관으로의 행동변화단계로 계획전단계, 계획 단계, 실천단계, 유지단계 등 4개의 단계로 보면 근로자에서의 금연에 대하여 각각 40.5 %, 23.7 %, 12.1 % 및 23.7 %, 운동에 대하여는 18.4 %, 37.6 %, 17.7 % 및 26.3 %, 음주하였던 사람중 절주에 대하여는 20.9 %, 15.4 %, 10.0 % 및 53.7 %이었다. 흡연을 하는 보건관리자의 행동단계가 일반근로자 보다 유의하게 많았다. 운동에 대해서는 근로자중 50세 이상과 생산직 근로자에서 계획전단계가 다른 근로자보다 유의하게 많았다. 결 론 : 이상의 결과로 대부분의 근로자가 금연을 제외하고는 건강한 생활습관으로의 행동변화를 원하는 것을 알 수 있었으며 근로자의 특성에 따라 행동 변화단계가 다르므로 이를 고려한 다양한 건강증진 프로그램을 개발함으로써 참여율 및 성공율을 높일 수 있으리라 사료된다. Objectives : This research attempts to investigate the relationship between health risk factors and workers' behavioral changes based on individual worker's characteristics to allow the development of more effective health promotion programs in businesses places. Methods : A questionnaire survey was conducted with 282 workers employed in small to medium sized enterprises in the Kyong-in area of Korea. The questionnaire was composed of general characteristics, a health risk assessment and an evaluation of the stage of behavior change for health promotion strategy in the workplace. Results : The health risk assessment revealed that 65.7 % of male workers smoke, 70.5% of male workers do not exercise on a regular basis, 86.1 % of female workers do not exercise at all, and 78.6 % of male workers and 50 % of female workers drink alcohol. In addition, the survey identified that 29.5% of male workers are addicted to excessive drinking, as are 11.1% of female workers. Based on the four stages of behavioral changes that lead to health, the pre-contemplation stage, contemplation stage, action stage, and maintenance stage, 40.5 %, 23.7 %, 12.1 % and 23.7 % of workers are in these stages, respectively, with regards to quitting smoking. As for regular exercises, 18.4 %, 37.6 %, 17.7 %, and 26.3 % of workers belong to each stage, respectively. As for moderation in drinking, 20.9 %, 15.4 %, 10.0 %, and 53.7 % are in each stage, respectively. The rate of health managers in the active stage of quitting smoking is significantly higher than that of general workers. Among the workers who do not exercise on a regular basis, workers over 50 years-old and blue color workers are more common in the precontemplation stage than any other worker groups. Conclusions : The results of this study suggest that the stages of behavioral change vary with worker characteristics. An awareness of the effects of the high risk factors is essectial for promoting workers' attendance in health promotion programs.

분산 시스템에서 히스토리 기법을 이용한 자기 학습 부하균등화

구용완,정진명 수원대학교 기초과학연구소 1996 基礎科學論文集 Vol.5 No.-

This study intended, for maximize resource utilization, to store system_state_information which periodically exchanged in distributed system into history table, and on the basic of the result, and proposed load balancing model performing nonpreemptive load balancing, and designed load balancing algorithm. When same job was scheduling later as load balancing scheduler having self-learning function on the basis of the stored content in history table(such as job type, working time, turnaround time, I/O time per job, etc., obtained from its past experience), this system positively decide whether transfer of that job to remote node is proper or not.

Comparison of Fermentation Characteristics of the Main Types of Chinese Cabbage Kimchi

Wan-Soo Park,Seong-Won Moon,Myung-Ki Lee,Byung-Hak Ahn,Young-Jo Koo,Kil-Hwan Kim 한국식품과학회 1996 Food Science and Biotechnology Vol.5 No.2

Definitive Radiotherapy versus Postoperative Radiotherapy for Tonsil Cancer

Koo, Tae Ryool,Wu, Hong-Gyun,Hah, J. Hun,Sung, Myung-Whun,Kim, Kwang-Hyun,Keam, Bhumsuk,Kim, Tae Min,Lee, Se-Hoon,Kim, Dong-Wan,Heo, Dae-Seog,Park, Charn Il Korean Cancer Association 2012 Cancer Research and Treatment Vol.44 No.4

<P><B>Purpose</B></P><P>The purpose of this study is to analyze treatment outcome of radiotherapy (RT) in patients with stage III-IV tonsil cancer managed by surgery followed by postoperative RT (SRT) and definitive chemoradiotherapy (CRT), and to thereby evaluate the most feasible treatment modality.</P><P><B>Materials and Methods</B></P><P>Of 124 patients, 67 underwent CRT, and 57 underwent SRT. We compared survival and complication rates in both groups.</P><P><B>Results</B></P><P>The median follow-up time was 57 months (range, 19 to 255 months) for surviving patients. At five years, locoregional progression-free survival (LRPFS) and overall survival (OS) were 88% and 80%, respectively. No significant difference in LRPFS (p=0.491) and OS (p=0.177) was observed between CRT and SRT. In multivariate analysis, old age and higher T stage showed a significant association with poor LRPFS, PFS, and OS; higher N stage showed an association with poor PFS and a trend of poor LRPFS, while no association with OS was observed; treatment modality (CRT and SRT) showed no association with LRFPS, PFS, and OS. Grade 3 or higher mucositis was observed in 12 patients (21%) in the SRT group, and 25 patients (37%) in the CRT group.</P><P><B>Conclusion</B></P><P>Definitive CRT and SRT have similar treatment outcomes for patients with stage III-IV tonsil cancer. Although acute complication rate appears to be higher in the CRT group, it should be noted that not all data on complications were included in this retrospective study. To determine the most feasible treatment modality, not only mucositis and xerostomia, but also emotional aspect and quality of life, should be considered.</P>

철도 사고 원인을 위한 수행도 영향 인자 분류

구락조(Koo Lock Jo),김동산(Kim Dong San),정명철(Jung Myung-Chul),백동현(Baek Dong Hyun),윤완철(Yoon Wan Chul) 한국철도학회 2006 한국철도학회 학술발표대회논문집 Vol.- No.-

The objective of this paper was to categorize performance shaping factors of human errors associated with railway accidents by reviewing reports published within and out of the country, especially Rail Safety & Standards Board (RSSB), and to validate their feasibility with domestic railway accident data. The systematically categorized 13 performance shaping factors were train/infrastructure/traffic, person, work schedule management, communication, procedure and documentation, information, team, in-cab environment, roles/responsibilities, training/knowledge/experience, workplace design/HMI, passive sign, and task management. Each factor was further analyzed into sub-factors. For the validation, 61 causal factors were extracted from 42 domestic railway accidents and then compared with the category. The category could include all 61 factors. The category of performance shaping factors for human errors that this study suggested may be useful to enhance railway safety.