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褥瘡에 대한 治驗 1 例 報告 : an External Therapy with ASTRAGALI RADIX Powder
허영란,문성호,최중길 대한본초학회 2000 大韓本草學會誌 Vol.15 No.2
Pressure sore is the ulceration and necrosis of the skin and underlying tissue usually occurred on the bony prominence of the body after prolonged or repeated pressure. Recently, the incidence of the pressure sore has been increased due to the development of the industry, increased number of the traffic accident and the cerebrovascular accident. Authors reviewed 4 sites of a patient who had received external application with ASTRAGALI RADIX powder for the pressure sore. Pressure sore of the patient was improved in about 4 months. ASTRAGALI RADIX has two effects: promoting tissue regeneration(生?) and evacuating the pus by administering tonics(????). So ASTRAGALI RADIX is proper for the external application of the pressure sore.
고강도 콘크리트(80MPa이상)를 이용한 콘크리트충전강관구조 적용을 위한 기초물성 연구
이장환,강용학,정근호,김진호,정상진,최문식 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2
One of the most important reasons that CFT is used in many conditions is by using that we can achieve the effect, which reduce the section of the member. This research purpose to find the most ideal composition, which is achieved by the investigation in the concrete's property of matter like ability of Slump, Slump Flow, Air content, Bleeding, and Settlement when the high strength of concrete which is over 80MPa is used m the CFT column.
CFT구조용 초고강도 충전 콘크리트의 현장 적용을 위한 실험적 연구
이장환,남정민,정근호,김진호,정상진,최문식 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)
Due to social problems such as the increasing of land price and the expanding of city, buildings require more complex and bigger components and structure. However, the complex and massive building projects need new technology to solve effect of local buckling and the needs for more space. Hence, Concrete Filled Tube Steel (CFT), the tube steel to hold concrete during pouring and curing of concrete procedure, which helps to reduce local buckling and space, was developed. Most researches on CFT might not be focused on the characteristic of concrete filled in tube but structural analysis. However, it is the essential factor to increase the strength of concrete on CFT for having efficient results. Therefore, this paper will describe how to apply CFT into the construction site through examining High Strength Concrete (800kg/cm2), the strength of core, and bleeding during pouring strategy.
서중조건하에서의 콘크리트 충전 강관 기둥의 시공을 위한 실험적 연구
이장환,강용학,정근호,김진호,최문식,정상진 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1(구조계)
The basic Physical properties, Slump, Slump flow, Air content, Bleeding, and Settlement of concrete was investigated to test Characteristic of Setting and to evaluate the relation between Model specimen and Heat of hydration for construction Over the High Temperature(CFT). The objective of this study is to take the partial core after the cementation of Model specimen, test the compression intensity and analyze the relation to Test piece.
손영준,송인명,양동일,정근호,정상진,최문식 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)
The column for Steel Framed Reinforced Concrete Structure (SFRCS) and the column for Reinforced Concrete Structure (RCS) could be the most common building structure. The increasing of the need for massive space hasaffected the size of building components for supporting the massive structure. However, the changing of components size makes inefficient space of building. Hence, to meet the need for acquiring efficient space comparing the budget and cost the new structure method, Concrete Filled Tube Steel (CFT), was developed. CFT is the structure for which steel tube instead of other materials such as wood for holding concrete is used. The most benefit of this one is to help in reducing the size of the building components and local buckling because of tube steel holding concrete. For this reason, this research will examine the probability of applying CFT on construction sites by using the concrete (800kg/cm2) especially for CFT through the data from the real size mock-up.
Choi, Jung Seok,Kwon, Ki Mun,Lee, Young Kyu,Joeng, Jang Uk,Lee, Kyung Ok,Jin, Sang Keun,Choi, Yang Il,Lee, Jae Joon Asian Australasian Association of Animal Productio 2018 Animal Bioscience Vol.31 No.10
Objective: This study was conducted to enable on-line prediction of primal and commercial cut weights in Korean slaughter pigs by AutoFom III, which non-invasively scans pig carcasses early after slaughter using ultrasonic sensors. Methods: A total of 162 Landrace, Yorkshire, and Duroc (LYD) pigs and 154 LYD pigs representing the yearly Korean slaughter distribution were included in the calibration and validation dataset, respectively. Partial least squares (PLS) models were developed for prediction of the weight of deboned shoulder blade, shoulder picnic, belly, loin, and ham. In addition, AutoFom III's ability to predict the weight of the commercial cuts of spare rib, jowl, false lean, back rib, diaphragm, and tenderloin was investigated. Each cut was manually prepared by local butchers and then recorded. Results: The cross-validated prediction accuracy ($R^2cv$) of the calibration models for deboned shoulder blade, shoulder picnic, loin, belly, and ham ranged from 0.77 to 0.86. The $R^2cv$ for tenderloin, spare rib, diaphragm, false lean, jowl, and back rib ranged from 0.34 to 0.62. Because the $R^2cv$ of the latter commercial cuts were less than 0.65, AutoFom III was less accurate for the prediction of those cuts. The root mean squares error of cross validation calibration (RMSECV) model was comparable to the root mean squares error of prediction (RMSEP), although the RMSECV was numerically higher than RMSEP for the deboned shoulder blade and belly. Conclusion: AutoFom III predicts the weight of deboned shoulder blade, shoulder picnic, loin, belly, and ham with high accuracy, and is a suitable process analytical tool for sorting pork primals in Korea. However, AutoFom III's prediction of smaller commercial Korean cuts is less accurate, which may be attributed to the lack of anatomical reference points and the lack of a good correlation between the scanned area of the carcass and those traits.
Jung-Hye Choi,In-Soon Kim,Il-Young Choi,Myung-Ju Ahn,Seock-Ah Im,Bong-Seog Kim,Ho-Suk Oh,Heung Woo Lee,Yeung Chul Mun,Chu-Myung Seong,Soon Nam Lee,Young-Yeul Lee 대한암학회 2003 Cancer Research and Treatment Vol.35 No.3
Purpose: Gemcitabine and 5-fluorouracil (5-FU) are twocompounds with reproducible activity against advancedpancreatic carcinomas. To evaluate the activity and feasibilityof this combination chemotherapy, a multi-institutionalphase II study was performed.Materials and Methods: Twenty patients (maleခfemale15ခ5, median age: 60.5 years), with histologically verifiedlocally advanced or metastatic pancreatic carcinomas,were enrolled between April 2000 and March 2002.Gemcitabine was administered by intravenous injectionat the doses of 1,000 mg/m2 on days 1, 8 and 15, and5-FU 800 mg/m2/day, was given by continuous intravenousinfusion on days 1~5. The treatment was repeatedevery 4 weeks. The clinical benefit response (CBR) wasa composite of the pain, Karnofsky performance statusand body weight change measurement.Results: Nineteen of the twenty patients were assessablefor response. The median follow-up duration was 4.6months (0.4~15.2 months). Five patients achieved a partialresponse and eight a stable disease. The overall responserate was 25.0%. The CBR was assessable in 12 patients.The overall CBR was 41.7% (5/12). The median survivalof all the patients was 8.0 months. Grade 3~4 toxicitiesincluded neutropenia (9.3%) and thrombocytopenia (5.3%).Conclusion: This study suggested that gemcitabine,combined with infusional 5-FU, was well tolerated, andproduced modest antitumor activity and symptomaticrelief in advanced pancreatic cancer patients. (Cancer Res Treat. 2003;35:213-217)
Immunological Monitoring of Urinary Aflatoxins and Estimation of Liver Cancer Incidence in Koreans
Choi, Mun-Jung,You, Young-Chan,Kim, Hyung-Sik,Lee, Byung-Mu Korean Society for Biochemistry and Molecular Biol 1996 Journal of biochemistry and molecular biology Vol.29 No.2
Polyclonal antiserum R101 against aflatoxin $B_1$ ($AFB_1$) was raised in New Zealand white rabbits after injection of bovine serum albumin-$AFB_1$ conjugate. Competitive ELISA (enzyme linked immuno-sorbent assay) demonstrated that antiserum R101 has the highest binding for $AFB_1$ (50% inhibition at 170 fmol) and aflatoxicol II (50% inhibition at 112 fmol). It also reacts with other aflatoxins such as $AFB_2$, $AFG_1$, $AFG_2$, and aflatoxin metabolites ($AFM_1$, $AFM_2$, $AFP_1$, and $AFQ_1$), but it does not cross-react with $AFG_2a$. Using this antiserum, aflatoxins were quantitated in 100 urine samples of undergraduate students at the College of Pharmacy, Sung Kyun Kwan University, Republic of Korea. By ELISA, $AFB_1$ and its metabolites were detected in human urine samples (N=100, male=89, female=11, ages=20~31 yrs) with a range of 1.4~200.6 ng/kg/day (mean$\pm$SD=$18.11{\pm}33.01\;ng\;AFB_1/kg/day$ in males, $3.82{\pm}2.65\;ng/kg/day$ in females). Assuming that urinary excretion is about 7.6% of $AFB_1$ intake (Groopman et al., 1992), we estimated that Koreans were daily exposed to a total dietary $AFB_1$ of $240.20{\pm}438.67\;ng/kg/day$ in males and $50.35{\pm}29.88\;ng/kg/day$ in females, respectively. When the human monitoring data was applied to a linear regression model of Y=21.67X-10.04 {Y=liver cancer incidence per 100,000, X=Log $AFB_1$ intake (ng/kg/day), r=0.99} developed from previously reported epidemiological data, calculated liver cancer incidences attributed to $AFB_1$ exposure were 41.56/100,000 in males and 26.84/100,000 in females. The incidences were similarly correlated with liver cancer mortality rates of 43.43/100,000 in males and 11.23/100,000 in females in Korea. These results suggest that aflatoxin exposure may be an important risk factor for the high incidence of liver cancer in Korea.
Choi, Jung-Ho,Rho, Mun-Chual,Lee, Seung-Woong,Choi, Ji-Na,Kim, Koan-Hoi,Song, Gyu-Young,Kim, Young-Kook 대한약학회 2008 Archives of Pharmacal Research Vol.31 No.11
Acyl-coenzyme A: cholesterol acyltransferase (ACAT) catalyzes cholesterol esterification and plays important roles in intestinal absorption of cholesterol, hepatic production of lipoproteins and accumulation of cholesteryl ester within macrophages and smooth muscle cells. Ethanol extract of Psoralea corylifolia showed a significant inhibition of ACAT enzyme. Via bioactivity-guided fractionation of the ethanol extract of Psoralea corylifolia, two prenylated flavonoids were isolated. Their structures were determined as bavachin (1) and isobavachalcone (2) by spectroscopic analysis ($^1H-$, ${13}C$-NMR, 2D-NMR, and ESI-MS). The $IC_{50}$ values were 86.0 (1) and 48.0 (2) ${\mu}M$ in the ACAT assay system using rat liver microsome. Compound 2 also decreased cholesteryl ester formations in HepG2 cells. In addition, this compound showed a noncompetitive type of inhibition of ACAT.
Mun Ho Choi,Jung Yong Ahn,Hun Kyu Choi,Byung-Hee Lee 대한신경외과학회 2003 Journal of Korean neurosurgical society Vol.33 No.2
Dural arteriovenous malformations may be congenital, but most dural arteriovenous malformations are acquired lesions. The acquired dural arteriovenous malformations are rarely associated with brain tumors. We describe a case of dural arteriovenous malformation at the non-dominant transverse-sigmoid sinus associated with a convexity meningioma on the same side. The lesion was spontaneously disappeared after removal of the meningioma, even though the dural arteriovenous malformation was not manipulated. The authors describe a possible pathophysiology of dural arteriovenous malformations associated with tumors at the remote area and spontaneous closure after tumor resection. Key words:Dural arteriovenous malformation;Sinus thrombosis;Meningioma;Pathophysiology.