비정질(Fe_(1-x)Ni_x) 77_Si_10B_13 합금의 전기적 특성

김택기,임영언,손홍재 충남대학교 공업교육연구소 1982 論文集 Vol.5 No.2

The electrical resistivity in amorphous (Fe_(1-x)Ni_x)_77Si_10B_13(0≤x≤1, interval of x : 0.1) alloys prepared by a rapid quenching method has been investigated as a function of Ni-concentration and temperature to study the relations between the structure and the properties of amorphous materials. The thickness of each specimen was derived from the density measured by the Archimedian method. The electrical resistance of the specimen was measured by 4-probe technique in the temperature range of 300-1100°K in the vacuum of 2 × 10^-5 torr. Findings follow: 1) The electrical resistivity for amorphous state except x=0.8 and 0.9 at room temperature is 1.5∼2 times as large as that for crystallized state and the electrical resistivity for both states reaches a maximum at about x=0.5 however, the electrical resistivity for x=0.8 and 0. 9 shows anomalous characteristics; i) the electrical resistivity for crystallized state is larger than that for amorphous state ii) the electrical resistivity for both states is very large in comparison with other compositions. 2) TCR (Temperature Coefficient of Resistivity) for amorphous state rises with increasing Ni-concentration and passes through a maximum at about x=0.5. 3) The crystallization temperature decreases linearly with increasing Ni-concentration.

Factors Related to Medication Adherence in Outpatients with Schizophrenia under More Than 5 Years of Treatment

Hong Kyu Ihm,Sang Hoon Kim,Jung Ho Kim,Kang Su Ha,Hyun Park 대한신경정신의학회 2016 신경정신의학 Vol.55 No.4

Objectives This study aimed to investigate the medication adherence rate and related factors in chronic schizophrenia. Methods A total of 65 (34 male and 31 female) outpatients with schizophrenia and with less than 5 years schizophrenia treatment were randomly selected to participate in the study survey. Medication adherence rate was evaluated by counting remaining tablets. The Korean version of Drug Attitude Inventory- 10 (KDAI- 10) was used to determine the subjective adherence rate. Adherence was defined as a patient taking more than 80% of their total prescribed medication. Positive KDAI- 10 scores indicate good adherence. Results The rate of good adherence was 87.7%. Our analysis showed that an older age (r=0.323, p=0.009), longer duration of illness (r=0.296, p=0.017), employment (F=4.41, p=0.016), remaining married (F=5.26, p=0.008), and being supported by family members, especially spouse or siblings (F=3.02, p=0.025) were significantly associated with good adherence. Presence of symptoms such as delusion (p=0.033) and hallucination (p=0.032) were related to poor adherence. Conclusion The results indicate that future study should investigate patient characteristics associated with medication adherence and analyze the clinician/patient alliance and its affect on adherence. The results also show that further studies might be useful in developing and validating measures of adherence, as well as in designing and evaluating interventions to improve adherent behaviors

판결문 분석을 통한 범죄 빅 데이터의 활용 가능성에 관한 소고

홍승표 ( Hong Seung Pyo ),임선영 ( Ihm Sun Young ),고으뜸 ( Go Eu Tteum ),홍성초 ( Hong Seong Cho ),김정운 ( Jin Zheng Yun ),임중연 ( Lim Joong Yeon ) 한국경찰학회 2020 한국경찰학회보 Vol.22 No.6

이 연구는 판결문 분석을 바탕으로 범죄 빅 데이터의 치안 분야 활용 가능성을 논의하는 것을 목적으로 한다. 이와 같은 연구 목적을 바탕으로 과학기술과 정보통신기술의 발달로 그 중요성이 커진 빅데이터에 대한 개념을 확인하고, 실제 수집한 빅 데이터에 대한 분석을 실시함으로써 빅 데이터를 다양한 분야에 활용할 수 있음을 확인하였다. 특히 범죄 관련 빅 데이터의 수집과 분석을 통해 경찰활동과 범죄예방활동, 그리고 범죄수사에까지 빅 데이터가 활용될 수 있음을 확인하였다. 연구 결과는 다음과 같다. 침입 범죄에 관한 판결문을 분석한 결과 대부분의 침입 범죄 사건이 유사한 경향성을 나타내는 것이 확인되었다. 다시 말해 침입 범죄의 경우 침입 범죄가 발생하는 지역과 시설, 수단과 방법 등에 있어 유사한 특징이 나타나는 것으로 확인되어 침입 범죄의 경향성을 확인할 수 있었다. 다음으로 이와 같은 연구 결과를 바탕으로 범죄 관련 빅 데이터의 활용을 통해 유사 범죄 검색 시스템의 개발을 제안하였다. 유사한 특징을 확인할 수 있는 시스템의 개발을 통해 범죄예방은 물론 범죄수사에 해당 시스템을 적용시켜 치안활동의 효과성과 효율성을 담보할 수 있을 것으로 예상할 수 있었다. Based on the analysis of the sentencing, the study aims to discuss the potential use of criminal big data in the security field. Research conducted for this purpose confirmed that big data can be used in various fields by identifying the concept of big data that has become more important due to the development of science and technology and information and communication technology and conducting analysis of big data collected in practice. In particular, the collection and analysis of big data related to crime confirmed that big data could be used for police activities, crime prevention activities, and criminal investigations. The results of the study are as follows: An analysis of the sentencing on intrusion crime confirmed that most of the intrusion crime cases indicated a similar tendencies. In other words, in the case of intrusion crimes, similar characteristics were found in the areas and facilities where intrusion crimes occurred, and the means and methods were found to confirm the tendency of intrusion crimes. Based on these findings, we then proposed the development of a similar crime search system through the use of crime-related big data. The development of a system that could identify similar characteristics could be expected to ensure the effectiveness and efficiency of policing activities by applying the system to criminal investigations as well as crime prevention.

성인 국소성 분절성 사구체 경화증의 임상경과 및 치료반응

홍화정(Hwa Jeong Hong),임천규(Chun Gyoo Ihm),최태진(Tae Jin Choi),이성배(Sung Bae Lee),최남수(Nam Soo Choi),홍성표(Sung Pyo Hong),이태원(Tae Won Lee),김명재(Myung Jae Kim),양문호(Mun Ho Yang) 대한내과학회 1998 대한내과학회지 Vol.54 No.2

N/A Background: The response to therapy in adult patients with nephrotic syndrome caused by primary focal segmental glomerulosclerosis (FSGS) was discouraging, but recent reports have shown high remission rate. Of these patients in remission, few progressed to end stage renal disease. Methods : we analyzed author's experiences in 42 Korean adults with primary FSGS between January 1986 and December 1995 in attempt to know the response to therapy and outcome. Results: 1) Twenty-six of 42 patients(62%) had nephrotir range proteinuria, and renal insufficiency (serum creatinine>1.4 mg/dL ) was present in 14 patients(34%). Nephrotic patients had higher serum level of creatinine than that of nonnephrotic patients, and there was no difference between the two groups in blood pressure, age, and hematuria. 2) Twenty-six patients with nephrotic range proteinuria received combined treatment with prednisolone and cyclophosphamide. Complete remission (proteinuria≤300 mg/d) was observed in 10 cases(39%), and partial remission(≤2.50g/d) in 10 cases(42%), with mean remission time of 4.1±2.2 months after initiation of treatment. They had remission within 6 months of therapy except one. Relapse was noticed in 11 cases (52%) during follow-up. 3) None of responder group progressed to ESRD, while two of 5 non-responders progressed to ESBD, but there was no significant difference in slope of inverse creatinine between two groups. 4) The degree of proteinuria, initial serum creatinine, age, and sex did not affect the patient's response to therapy 5) The risk factors related to progression of renal failure were the initial serum creatinine level and degree of proteinuria. Conclusion: Nephrotic adult patients with primary FSGS may benefit from a more prolonged course of therapy with prednisolone and cyclophosphamide.

Dipeptidyl peptidase 4 inhibitor attenuates obesity-induced myocardial fibrosis by inhibiting transforming growth factor-βl and Smad2/3 pathways in high-fat diet-induced obesity rat model

Hong, S.K.,Choo, E.H.,Ihm, S.H.,Chang, K.,Seung, K.B. W.B.Saunders [etc.] 2017 clinical and experimental Vol.76 No.-

<P>Obesity-induced myocardial fibrosis may lead to diastolic dysfunction and ultimately heart failure. Activation of the transforming growth factor (TGF)-beta 1 and its downstream Smad2/3 pathways may play a pivotal role in the pathogenesis of obesity-induced myocardial fibrosis, and the antidiabetic dipeptidyl peptidase 4 inhibitors (DPP4i) might affect these pathways. We investigated whether DPP4i reduces myocardial fibrosis by inhibiting the TGF-beta 1 and Smad2/3 pathways in the myocardium of a diet-induced obesity (DIO) rat model. Eight-week-old male spontaneously hypertensive rats (SHRs) were fed either a normal fat diet (chow) or a high-fat diet (HFD) and then the HFD-fed SHRs were randomized to either the DPP4i (MK-0626) or control (distilled water) groups for 12 weeks. At 20 weeks old, all the rats underwent hemodynamic and metabolic studies and Doppler echocardiography. Compared with the normal fat diet (chow)-fed SHRs, the HFD-fed SHRs developed a more intense degree of hyperglycemia and dyslipidemia and showed a constellation of left ventricular (LV) diastolic dysfunction, and exacerbated myocardial fibrosis, as well as activation of the TGF-beta 1 and Smad2/3 pathways. DPP4i significantly improved the metabolic and hemodynamic parameters. The echocardiogram showed that DPP4i improved the LV diastolic dysfunction (early to late ventricular filling velocity [E/A] ratio, 1.49 +/- 0.21 vs. 1.77 +/- 0.09, p < 0.05). Furthermore, DPP4i significantly reduced myocardial fibrosis and collagen production by the myocardium and suppressed TGF-beta 1 and phosphorylation of Smad2/3 in the heart. In addition, DPP4i decreased TGF-beta 1-induced collagen production and TGF-beta 1-mediated phosphorylation and nuclear translocation of Smad2/3 in rat cardiac fibroblasts. In conclusion, DPP4 inhibition attenuated myocardial fibrosis and improved LV diastolic dysfunction in a DIO rat model by modulating the TGF-beta 1 and Smad2/3 pathways. (C) 2017 Elsevier Inc. All rights reserved.</P>

Case Report : A Case of Syndrome of Inappropriate Scretion of Anti-Diuretic Hormone Associated with Sodium Valproate

( Hong Joo Lee ),( Jung Kook Wi ),( Ju Young Moon ),( Kyung Hwan Jeong ),( Chun Gyoo Ihm ),( Sang Ho Lee ),( Tae Won Lee ) 대한전해질학회 2012 Electrolytes & Blood Pressure Vol.10 No.1

We report a rare case of the concurrent manifestation of central diabetes insipidus (CDI) and type 2 diabetes mellitus (DM). A 56 year-old man was diagnosed as a type 2 DM on the basis of hyperglycemia with polyuria and polydipsia at a local clinic two months ago and started an oral hypoglycemic medication, but resulted in no symptomatic improvement at all. Upon admission to the university hospital, the patient`s initial fasting blood sugar level was 140mg/dL, and he showed polydipsic and polyuric conditions more than 8 L urine/day. Despite the hyperglycemia controlled with metformin and diet, his symptoms persisted. Further investigations including water deprivation test confirmed the coexisting CDI of unknown origin, and the patient`s symptoms including an intense thirst were markedly improved by desmopressin nasal spray (10 μg/day). The possibility of a common origin of CDI and type 2 DM is raised in a review of the few relevant adult cases in the literature.

혈관내 초음파를 이용한 국소형과 미만형 관동맥 경련부위의 형태학적 차이

임상현,승기배,장기육,김범준,정해억,강동헌,정욱성,김종진,박인수,김재형,홍순조,최규보 대한순환기학회 2001 Korean Circulation Journal Vol.31 No.8

CaO-CaF₂-Fe₂O₃계 Slag에 의한 탄소포화 용철의 동시탈인, 탈황에 관한 연구

임성규,김영홍 울산대학교 1990 연구논문집 Vol.21 No.1

실험적 규모로 CaO-CaF₂-Fe₂O₃계 Slag를 사용하여 1350℃에서 탈인 및 탈황에 대한 거동을 규명하였다. 실험조건 용선의 초기 [Si]함량, Fe₂O₃첨가량 및 염기도를 변화시켜 결정하였다. 본 실험으로 얻어진 결과는 다음과 같다. 1) 용선중 초기 [Si]함량이 적을수록 탈인 반응에는 유리하게 작용하나, 탈황반응에는 [Si]함량이 높을수록 활발히 진행되었다. 2) 적정한 동시탈인, 탈황반응을 위하여 용선의 초기 [Si]함량이 낮아야 효율적이다. 3) 용선중 [P]의 농도는 Slag Feeding말기에 최저 수준으로 떨어졌으며, 그후 복인현상이 현저히 나타났다. 한편, 탈황반응은 복황현상이 나타나지 않았다. 4) 동시 탈인, 탈황반응에 미치는 염기도의 영향은 매우 크며, 적정염기도는 3이상이었다. 이상의 실험결과는 실제 제강조업과 일치하는 것이며, Bubbling법에 의한 CaO-CaF₂-Fe₂O₃계 Slag로부터 탄소 포화용철에 대한 탈인, 탈황율은 각각 85%와 80%를 얻을 수 있었다. Laboratory-scale experiments using CaO-CaF₂-Fe₂O₃slags were carried out to clarify the behaviors of dephosphorization and desulfurization in carbon-saturated iron a 1350℃. Experimental conditions were determined by varying initial silicon content in the molten metal, amount of Fe₂O₃and basicity of slag. The results obtained in this study were as follows. 1) The beneficial effect of lower initial silicon content in liquid iron on dephosphorization was not applied to the desulfurization. 2) It was necessary to lower initial silicon content to the appropriate value for the purpose of simultaneous dephosphorization and desulfurization. 3) The phosphorous concentration fell to a minimum value soon after the end of slag feedding, and noticeable reversion of phosphorous follow thereafter. On the other hand, substantial reversion of sulfur was not observed. 4) The influence of the slag basicity on the simultaneous dephophorization and desulfurization was great, then optimum basicity was more than 3. The results of the experiment are corresponding to the steelmaking stage. It was found that high dephosphorization and desulfurization (85% and 80%) were obtained by CaO-CaF₂-Fe₂O₃slag with N₂gas bubbling condition.

초기 제 2 형 당뇨 환자에서 우심실 이완기 기능장애에 관한 연구

임상현,박인수,윤호중,김재형,홍순조,최규보 대한순환기학회 2003 Korean Circulation Journal Vol.33 No.6

개흉 잡견에서 심방-양심실 조율의 혈역학적 효과

임상현,노태호,조은주,진승원,김희열,이만영,김종진,김재형,홍순조,최규보 대한순환기학회 2001 Korean Circulation Journal Vol.31 No.4