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      • 제주 돼지의 사육개선을 위한 기초조사 연구

        한성욱,김형균,강태숙 제주대학교 1971 논문집 Vol.3 No.-

        . The raising and feeding of swine in outhouses(Toilet) arose long ago and become a habit or custom for excrement control. The primary reason for practice is that most Cheju people simply do not like to tauch human feces. As a result of swine living in outhouses (Toilet) there is a great danger to humans of infection with cysticercus cellulosae from eating improperly cooked pork. Farmers do not recognize the offet of cysticercus cellulosae on human beings and must receive adequate education. We can slowly eliminate this problom by teaching and re emphasizing the unsanitary conditions and economic loss arising from this practice of W, C swine raising. The local governments and educated citizens as well as know ledgeable farmers must give continuous instruction and guidance in sanitary practices if we are to alter and eliminate swine feeding in the toilet 1. In Cheju-do the family does not include married children, thus the families are necessarily smaller than the mainland and the number of pigs at any house depends upon number of peoples in the family thus it is usually impossible to feed more than one pig since human feces are utilized as pig feed. 2. Since farmers have only a small amount of feed and feces and aware that the growth rate during a pig's first year is greater than its growth rate during the second year thus indicating a highly efficient utilization of feed during the first year, the farmers usually sell the pig within the first year. 3. Since there is a shortage of sanitary pig feed in Cheju-do greater use should be made of the waste products left over from sweet potato starch production. 4. The primary reason for raising the pig in the toilet is that about 90% of the people do not like to touch human feces out of habit. 5. The first objective in improving the feeding of Cheju swine is the instruction of farmers in the sanitation and health problems and econmic loss involved in raising pigs in the toilet because about 50% of the farmers are ignorant of even the existence of cysticercus cellulosae and its due effect on human beings.

      • KCI등재후보

        중·고교 지리학습에서 등고선도를 이용한 지형이해

        한균형 한국지리환경교육학회 2003 한국지리환경교육학회지 Vol.11 No.1

        지형의 파악은 지표면의 이용과 직접적인 연관이 있기 때문에 지표면 형태의 연구는 지리학에 서 매우 중요한 부분이 되고 있다. 지형의 파악을 위해서는 주로 등고선을 이용하는 방법이 많았지만, 본 연구는 단면도를 이용하여 지표 형태를 파악할 수 있는 방법을 고안하였다. 특히, 3단계의 훈련을 거쳐 단면도를 통해 지형을 분석하고 파악하는 방법을 제시해 보았다. 각 단계마다 까다로운 부분이 있었으나, 실습을 거듭하면서 지형이해에 쉽게 접근할 수 있으리라 여겨졌다. 1단계는 한 선의 단면선에 따라, 2단계는 특정 지역에서, 3단계는 지역 전체의 전반적인 경사 추세를 파악하여 지형을 이해하는 방법으로 진행하였다. 실제 학생들을 선별해 실습에 적용시켜 본 결과, 좋은 반응이 나타났다. : Studying geomorphology is very closely related with surface of the earth; especially land use. So this study is very important area teached in the middle and high school geography study. The method which has been adopted in this research are three stages ; First, draw a cross section line, and then the degree of slope is understood along the section line. Second, draw many section lines to know the wider area slope, Third find general whole area slope which wanted to know. these three stages were pre-tested by some of middle and high school students, which resulted very favorable.

      • 비강 및 비인두에 발생한 도립유두종과 편평상피암종의 p53단백 및 세포증식능에 관한 연구

        한주호,윤기중,이재규,신대균,박근호,조향정,문형배 圓光大學校 醫科學硏究所 1996 圓光醫科學 Vol.12 No.2

        The inverted papilloma and squamous cell carcinoma are common neoplasia in the sinonasal cavity and nasopharynx, but the incidence of these tumors are very low and the study on the oncogenesis or biological activity of the tumor cells are not well known. This study was designed to evaluate the oncogenic roles of the p53 gene and the proliferative activity of the tumor cells in the inflammatory polyp, inverted papilloma and squamous cell carcinoma. The experiment was carried by the immunohistochemical stains about the p53 protein, PCNA and Ki-67, histochemical stain about the AgNORs. and flow cytometric analysis about the DNA ploidy using the formalin fixed paraffin embedded tissues. The frequency of the expression of p53 protein was 0%(0/16 cases) in the inflammatory polyps, 18.8% (3/16 cases) in the inverted papillomas, and 87.5%(14/16 cases) in the squamous cell carcinomas. The labelling index(%) of the PCNA and Ki-67 was 5.3% and 3.3% in the inflammatoy polyps, 29.6% and 25.2% in the inverted papillomas, and 51.9% and 36.8% in the squamous cell carcinoma. The expression of the PCNA and Ki-67 was distributed in the periphery of the tumor islands of the inverted papilloma and was distributed in the both of center and periphery of the tumor islands of the squamous cell carcinoma. The number of nuclear AgNORs was increased in the order of inflammatory polyps (0.96), inverted papillomas(1.34) and squamous cell carcinoma(2.09). The frequency of the DNA aneuploidy was 0%(0/16 cases) in the inflammatory polyps, 18.8%(3/16 cases) in the inverted papillomas. and 12.5%(2/16 cases) in the squamous cell carcinomas. Above results indicates that the changes of the p53 gene and proliferative activity of the tumor cells are involved on the oncogenesis and the biological activity of the inverted papilloma or squamous cell carcinoma in the nasopharynx and sinonasa cavity.

      • KCI등재후보

        흰쥐 Nucleus Raphe Magnus에 투여한 Morphine이 척수 Serotonin 유리에 미치는 영향에 관한 연구

        이신재,임요한,최영님,김형룡,정동균 대한구강생물학회 1991 International Journal of Oral Biology Vol.15 No.1

        It is known that the interaction between opioid neuron and serotonergic neuron in bulbospinal pathway has an important role on pain control. This experiment was perfomed to directly measure the release of serotonin into spinal cord superfusates before and after the microinjection of morphine and its antagonist, naloxone into the NRM of rats. High performance liquid chromatography with electrochemical detection was used to quantitate the amine. The injection of morphine into the NRM induced a significant increase in the amount of serotonin released in the spinal cord, which was reversed after the intraperitioneal injection of naloxone. These results support the proposal that : the analgesia produced by morphine microinjected into the NRM is mediated by the activation of spinally projecting serotonergic neuron.

      • KCI등재SCIESCOPUS

        Highly stable hafnium–tin–zinc oxide thin film transistors with stacked bilayer active layers

        Han, Dong-Suk,Park, Jae-Hyung,Kang, Min-Soo,Choi, Duck-Kyun,Park, Jong-Wan Elsevier 2015 Current Applied Physics Vol.15 No.2

        <P>Hf-Sn-Zn-O (HTZO) thin films were prepared on SiO2/SiNx substrates at room temperature by the direct current (DC) magnetron sputtering of Hf-doped Sn-Zn-O targets. The characteristics of films with different amounts of Hf were analyzed. Amorphous HTZO films were obtained by increasing the Hf content, while polycrystalline films have not shown with Hf doping. With the proper Hf concentration in the HTZO films (similar to 2.0 atomic % Hf/(Hf + Sn + Zn + O)), HTZO films demonstrated good performance as an oxide semiconductor channel material in thin film transistors (TFTs) with a field effect mobility (mu(FE)) of 10.9 cm(2)V(-1) s(-1), an on/off current ratio of 10(9), and a subthreshold voltage swing of 0.71 V/decade. (C) 2014 Elsevier B. V. All rights reserved.</P>

      • KCI등재

        Scavenging Effect of Bee Venom for Acua-acupuncture against Nitric Oxide

        Han, Sang Won,Seo, Jung Chul,Koh, Hyung Kyun,Kim, Ee Hwa,Chung, Joo Ho,Kim, Chang Ju,Leem, Kang Hyun,Yoo, Yeong Min,Yin, Chang Shik 대한침구학회 2001 대한침구의학회지 Vol.18 No.6

        목적 : 본 연구는 최근 임상에서 많이 사용하는 봉독약침액의 nitric oxide (NO)에 대한 소거효과를 분석하기 위하여 실행되었다. 방법 : 양성대조군으로 비타민과 실험군으로 국산 봉독과 미국산 봉독에 NO를 분비하는 S-nitroso-N-acetylpenicillarnine (SNAP)을 투여한 후 NO의 농도를 540 nm 파장의 자외선 흡수량을 측정하여 평가하였다. 결과 : 국산 봉독은 100㎍/㎖에서 SNAP 처리 1.5, 3, 6 및 12시간에 대조군 (100%)과 비교하여 각각 86.7±1.5, 103.8±1.9, 88.3±2.9 및 85.6±3.2%의 잔류 NO 농도를 보였고, 1.5, 6 및 12시간에서 유의한 NO 소거 효과를 나타냈다. 미국산 봉독에서는 각각 74.0±2.2, 66.5±10.9, 86.1±2.8 및 59.1±3.8%로 모든 시간에서 유의한 결과를 보였다. 결론 : 이상의 봉독의 NO 소거효과는 봉독 약침액이 임상에서 동통, 종창, 등에 치료에 사용하는 작용기전의 하나로 사료된다.

      • KCI등재
      • Complete genome sequence of multidrug-resistant <i>Staphylococcus sciuri</i> strain SNUDS-18 isolated from a farmed duck in South Korea

        Han, Jee Eun,Lee, Seungki,Jeong, Dae Gwin,Yoon, Sun-Woo,Kim, Doo-Jin,Lee, Moo-Seung,Kim, Hye Kwon,Park, Sung-Kyun,Kim, Ji Hyung,Park, Se Chang Elsevier 2017 Journal of global antimicrobial resistance Vol.11 No.-

        <P><B>Abstract</B></P> <P><B>Objectives</B></P> <P>This study aimed to determine the complete genome sequence of multidrug-resistant <I>Staphylococcus sciuri</I> strain SNUDS-18 isolated from a farmed duck in South Korea.</P> <P><B>Methods</B></P> <P>Genomic DNA was sequenced using a PacBio RS II system. The obtained genome was annotated and antimicrobial resistance and virulence genes were identified.</P> <P><B>Results</B></P> <P>The sequenced genome possessed a <I>mecA</I> homologue (<I>mecA1</I>) that was almost identical to that of other oxacillin-susceptible <I>S. sciuri</I> strains, whereas the staphylococcal cassette chromosome <I>mec</I> (SCC<I>mec</I>) was not detected. Moreover, various antimicrobial resistance genes conferring resistance to β-lactams, aminoglycosides, phenicols, tetracycline and macrolide–lincosamide–streptogramin B (MLS<SUB>B</SUB>) antimicrobials were identified.</P> <P><B>Conclusions</B></P> <P>The SNUDS-18 genome and its associated genomic data will provide important insights into the biodiversity of the <I>S. sciuri</I> group as well as valuable information for the control of this potential pathogen.</P>

      • KCI등재

        만성 정신분열병 환자의 재활치료와 자아정체감 형성

        신현균,한일우,이영문 大韓神經精神醫學會 1994 신경정신의학 Vol.33 No.4

        The authors compared the subscale scores of ego identity scale between chronic schizophrenics(N=77) and control group(N=51) in order to investigate ego development of chronic schizophrenics who participated rehabilitative treatment. The results were as follows: 1)The rehabilitation group had higher score in the sense f self subscale of ego identity scale than control group. 2)According to sex difference, male group had higher score in the sense of self and self acceptance subscale of ego identity scale than female group. 3)According to sex difference within rehabilitation group, male reabilitation group had higher score in the self acceptance subscale of ego identity scale than female rehabilitation group, but in the interpersonal role expectation subscale the results were reversed.

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