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      • Para형 다단맥동 추출탑의 유동특성과 물질전달

        윤장효,염경호,김우식,김원규 연세대학교 대학원 1986 延世論叢 Vol.22 No.1

        The dynamic characteristics and mass transfer effects in Para-type plate pulsed column was investigated. The axial dispersion coefficient of continuous phase was constant in the range above that continuous phase flow rate was 200ml/min, and was more influnced by amplitude than by frequency. The hold-up of continuous phase was more influnced by amplitude and saunter mean diameter was more influnced by frequency. As the experimental results of acetone extraction, the column efficiency was slightly decreased with the pulse velocity increased, but was stabilized in the range of 80~90%. The acetone concentration profiles with the change of column height at steady state more approached to the backflow model than the diffusion model.

      • KCI등재후보

        교정용 미니스크류 식립 시 스크류의 길이, 직경 및 피질골 두께에 따른 응력 분포에 관한 3차원 유한요소법적 연구

        임종원,김왕식,김일규,손충렬,변효인 대한치과교정학회 2003 대한치과교정학회지 Vol.33 No.1

        본 연구는 교정치료 시 고정원 보강을 위해 사용되는 교정용 미니스크류의 길이, 직경 및 피질골 두께에 따른 응력분포 양상을 알아보기 위하여 시행되었다. 미니스크류의 길이와 직경 변화에 따른 응력 분포 양상을 관찰하기 위하여 식립되는 피질골의 두께를 1.0mm로 고정하고 미니스크류의 길이를 6.0mm, 8.0mm, 10.0mm, 12.0mm로, 직경을 1.2mm, 1.6mm, 2.0mm인 3차원 유한요소 모델을 제작하였다. 또한, 피질골의 두께 변화에 따른 응력 분포 양상을 관찰하기 위하여 미니스크류의 길이를 0.8mm로 고정하고 직경은 1.2mm, 1.6mm, 2.0mm로, 피질골의 두께는 1.0mm, 1.5mm, 2.0mm, 2.5mm인 3차원 유한 요소 모델을 제작하였다. 각각의 유한요소 모델의 미니스크류 head 중심에 200gm의 수평력을 가하여 응력 분포 양상과 크기를 3차원 유한요소 해석 프로그램인 ANSYS응 이용하여 비교한 결과 다음과 같은 결론을 얻었다. 1. 미니스크류 내부에서 나타나는 최대 응력값을 비교한 결과, 미니스크류의 직경이 1.2mm에서 2.0mm로 증가할수록 응력이 감소하였으며 같은 직경에서는 길이 증가에 상관없이 일정한 값을 유지하였다. 2. 피질골 및 해면골에 작용되는 최대 응력값을 비교한 결과, 미니스크류의 직경이 1.2mm에서 2.0mm로 증가할수록 응력이 감소하였으며 같은 직경에서는 길이 증가에 상관없이 일정한 값을 유지하였다. 3. 피질골 및 해면골에 작용되는 응력 분포를 관찰한 결과, 대부분의 응력이 피질골에서 흡수 되었으며, 해면골에 전달되는 응력값은 미미하였다. 4. 피질골 두께에 따른 최대 응력값을 비교한 결과, 같은 미니스크류의 직경에서는 피질골의 두께 증가에 상관없이 일정한 값을 유지하였다. 이상의 결과는 교정용 미니스크류의 유지에 길이보다는 직경이 더 크게 관여하는 것으로 나타나 미니스크류의 식립시 이에 대한 고려가 필요함을 시사하였다. The purpose of the present study is to evaluate the stress distribution on the length and diameter of the miniscrew and cortical bone width. Three dimensional finite element models were made of diameter 1.2mm, 1.6mm, 2.0mm and length 6.0mm, 8.0mm, 10.0mm, 12.0mm and cortical bone width 1.0mm. Also, another three dimensional finite element models were made of diameter 1.2mm, 1.6mm, 2.0mm and length 8.0mm and cortical bone width 1.0mm, 1.5mm, 2.0mm, 2.5mm, Two-hundred grams horizontal force were applied on the center of the miniscrew head and at that stress distribution and its magnitude had been analyzed by ANSYS, which is three dimensional finite element analysis program. The obtained results were as follows : 1. The comparison of the maximum von-Mises stress in the miniscrew showed that as the diameter increases from 1.2mm to 2.0mm stress has been decreased, while on the same diameter stress was not changed regardless of the length change. 2. The comparison of the maximum von-Mises stress in the cortical and cancellous bone showed that as the diameter increases from 1.2mm to 2.0mm stress has been decreased, while on the same diameter stress was not changed regardless of the length change. 3. In the analysis of the stress distribution in the cortical and cancellous bone, the most of the stress had been absorbed in the cortical bone, and did not transmitted much to the cancellous bone. 4. In the analysis of the maximum von-Mises stress according to the cortical bone width, the same diameter of the miniscrew showed a constant stress value regardless of the cortical bone width change. The above results suggest that the maintenance of the miniscrew is more reliable on diameter than length of the miniscrew.

      • Seasonal Fluctuation and Vertical Microdistribution of Drosophilid Flies Dwelling in the Broad-leaved Forests on Cheju-do(Quelpart Island)

        김원택,김승범,정세호,강효식 濟州大學校 師範大學 科學敎育硏究所 1995 科學敎育 Vol.12 No.1

        Community organization of the drosophilid flies was investigated with respect to the seasonal variation in species abundance and vertical microdistribution on the basis of the trapped collections in the two natural forests on Cheju-do from May to October 1994. The dominant species were Drosophila bizonata. D. curviceps. D. lutescens. D. angularis. D. pengi. and D. immigrans in the annual collections. The pattern in seasonal changes of the dominant species was similar at the two survey sites. Seasonal fluctuation in the species diversity was more affected by evenness than by species richness (number of species). The seasonal variation of abundance showed an unimodal pattern in all of the dominant species. The seasonal patterns of vertical microdistribution revealed difference in some of the dominant species between the two survey sites. These results suggest that the predominant species in the forest avoid niche overlap by means of seasonal separation of breedings and that the vertical microdistribution is strongly affected by factors associated with season and vertical site in the deep wooded forests.

      • 급성 골수성 백혈병 환자에서 발생한 침습성 아스페르길루스중에 대한 수술적치료 1 예

        배영환;어원식;어상민;김승만 김태영;박수영;서영경;정은주;안효정 인제대학교 2011 仁濟醫學 Vol.32 No.-

        Invasive pulmonary aspergillosis is known to have a poor prognosis and major cause of morbidity and motality in patients with hematologic disease. Without adequate therapy, invasive pulmonary aspergillosis will almost always progress to fatal pneumonia. Early administration of antifungal agents in patient with invasive pulmonary aspergillosis is most important. And surgical resection of aspergillous-infected tissue may be useful in patients with lesions that are contiguous with great vessel and lesions causing hemoptysis. We reported a rare case of surgical resection as curative treatment for invasive pulmonary aspergillosis patient in 58-year-old man who had the history of acute myeloid leukemia.

      • 임상가검물에서 분리된 효모의 임상적 의의

        유병용,이원길,김재식,전효진,노략균,이장백,김중명 慶北大學校 醫科大學 1990 慶北醫大誌 Vol.31 No.4

        1988년 1월부터 동년 12월말까지 경북대학교병원 임상병리과에 의뢰된 가검물 중에서 효모가 분리되었던 환자는 159명이었고, 남자와 여자의 비율은 1.8이었으며 1세 이하와 30세 이상에서 많았다. 또 분리 동정된 효모 총 159주 중 객담에서 78주(49.1%), 요에서 64주(40.3%), 복막액 5주(3.1%) 편도와 대변 각각 4주(2.5%), 농에서 3주(1.9%) 뇌척수액에서 1주(0.6%) 순으로 분리되었다. 분리된 효모로는 Candida albicans가 68주(42.8%), Candida tropicalis 33주(20.8%) Torulopsis glabrata 20주(12.6%), Candida parapsilosis 17주(10.7%), Trichosporon beigelli 7주(4.4%), Torulopsis candida 5주(3.1%), Torulopsis inconspicua와 Saccharomyces cerevisiae가 각 4주(2.5%), Candida guilliermondii 1주(0.6%) 순으로 있었다. 환자들의 기존질병은 폐질환이 70예, 요로질환이 40예 악성종양 및 당뇨병이 각 22예, 간질환 16예, 순환기 질환이 12예 등으로 나타났으며, 유인중 항생제 사용은 114예(80.0%), 수술 49예(34.3%), 카테터 46예(32.2%), 스테로이드사용 28예(19.6%) 악성종양과 당뇨병이 22예(15.4%), 항암제 사용이 10예(7.0%)로 나타났다. 유인이 2개 중복된 경우는 43예, 3개 중복은 38예, 4개는 11예, 5개는 2예로 나타났다. Yeast infection is commonest fungal infection of human. And their incidence becomes to be increased as the frequency of altered host immune system is increased. Antibiotics, cytotoxic drug, malignancy, diabetes mellitus, operative procedures and catherizations are predisposition of fungal infection. Since antifungal drug within a selective or narrow range of activity are available, it is important that speciation of yeast in routine clinical microbiology practice should be effected rapidly and reliably. Author isolated 159 strains of yeast and that were identified by API 20C Auxanogram®. Patient charts were reviewed retrogradely in order to find predisposing factors of isolated yeast cells. Yeast isolation is 1.8(102:57) of male to female rtio and is more frequently below 1 year-old and above 30 year-old in both sexes. Septum(49.1%). urine(40.3%) were major specimens in which yeast isolated. Candida albicans(42.8%), Candida tropicalis(20.8%), Torulopsis glabrata(12.6%), Candida parapsilosis(10.7%) were frequently identified species in order. Candida albicans and Candida parapsilosis were frequently isolated species among various specimens. Pulmonary diseases, urinary tract diseases, malignancy, and diabetes mellitus were major underlying diseases. And antibiotic(80.0%), operative procedure(34.3%), catherterization(32.2%), steroid(19.6%), malignancy(15.4%), diabetes mellitus(15.4%) and cytotoxic drug(7.0%) were predisposed in order.

      • Cholesterol-lowering Agents Decreased NAS Score without Intrahepatic Fat Improvement in Patients with Non-alcoholic Fatty Liver Disease: Systematic Review with Meta-analysis

        ( Hyo Young Lee ),( Dae Won Jun ),( Hyunwoo Oh ),( Waqar Khalid Saeed ),( Jae Yoon Jeong ),( Joo Hyun Sohn ),( Chang Hong Lee ),( Hyun Jung Kim ),( Hyeong Sik Ahn ) 대한간학회 2016 춘·추계 학술대회 (KASL) Vol.2016 No.1

        Aims: A number of clinical trials reported diverse effects of cholesterol- lowering agents in nonalcoholic fatty liver disease (NAFLD) patients. We, therefore, assessed the changes in non-alcoholic steatohepatitis activity score (NAS) and intrahepatic fat contents after treatment with cholesterol lowering agents in NAFLD patients by performing a meta-analysis. Methods: The Cochrane library, the MEDLINE, and the EMBASE databases were searched until June 2015, without any language restrictions, for randomized controlled trials (RCTs) and non-randomized studies (NRSs); additional references were obtained from reviewed articles. The quality of evidence was assessed using the grading of recommendations assessment, development and evaluation guidelines. Results: Three RCTs and three NRSs (235 participants) met the inclusion criteria for this updated systematic review. Liver biopsy was performed in three RCTs, but only the two studies reported NAS. Ezetimibe showed decreased NAS (Pooled RR: -0.65, 95% CI: -1.15 ~ -0.015). The intrahepatic fat contents were not decreased in RCTs, while they were decreased in NRSs. The baseline cholesterol level in all three RCTs was lower than the three NRSs (191mg/dl vs. 227.5mg/dl). The pre-planned secondary outcomes of AST, ALT, Glucose, HbA1c analysis did not show significant difference after treatment with cholesterol lowering agents. Conclusions: Ezetemibe decreased NAS score without improving intrahepatic fat contents.

      • KCI등재후보
      • KCI등재
      • Identification of the male produced aggregation-sex pheromone of Monochamus saltuarius, a major insect vector of the pine wood nematode in Korea

        Hyo-Rim Lee,Sung-Chan Lee,Dong Ha Lee,Won-Sil Choi,Chan-Sik Jung,Jae-Ho Jeon,Jeong-Eun Kim,Il-Kwon Park 한국응용곤충학회 2017 한국응용곤충학회 학술대회논문집 Vol.2017 No.10

        In this study, we isolated and identified an aggregation-sex pheromone from Monochamus saltuarius, the major insectvector of the pine wood nematode in Korea. Adult male of M. saltuarius produces 2-undecyloxy-1-ethanol, which is knownto be an aggregation-sex pheromone in other Monochamus species. We performed field experiments to determine the attractivenessof the pheromone and other synergists. More M. saltuarius adult beetles were attracted to traps baited with the pheromonethan to unbaited traps. Ethanol and (-)-α-pinene interacted synergistically with the pheromone. Traps baited with pheromone+(-)-α-pinene+ethanol were more attractive to M. saltuarius adults than traps baited with pheromone, (-)-α-pinene, or ethanol alone.Ipsenol, ipsdienol, and limonene were also identified as synergists of the aggregation-sex pheromone for M. saltuarius adults.

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