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      • SCOPUSSCIEKCI등재

        상악골 급속확장술식 전후 두경부 자세와 설골위치의 변화에 관한 연구

        배현철,차경석,이진우 대한치과교정학회 1997 대한치과교정학회지 Vol.27 No.4

        본 연구는 상악골 급속확장술식 후 호홉변화와 연관된 두경부 자세의 변화와 이에 따른 설골 위치 변화의 양상을 알아보기 위하여 시행하였다. 평균연령이 12세 9개월이고 Hellman stage Ⅲc에서 adult stage까지의 인두강이 정상적이며 상악골 급속활장술식을 시행한 Angle씨 Ⅲ급 골격양상의 남녀환자 32명을 대상으로 하여 이들 중 상악골 급속확장술식 시행 후 두경부각도가 증가된 군을 A군으로, 감소된 군을 B군으로 분류하였고 대조군은 연구대상과 동일한 Hellman stage이며 평균연령 12세 7개월의 Angle I급 골격양상을 띠는 남녀환자 23명으로 이들을 C군으로 하여 골격양상과 인두강크기, 두경부자세, 설골 위치에 대한 항목을 연구하여 다음과 같은 결론을 얻었다. 1. 골격양상과 인두강 비교 1) A, B군의 치료 전후 비교에서, 두 군 공히 하악이 하방경사되었고 인두강 크기는 변화가 없었다. 2) 세 군간의 치료 전후를 각가 비교한 결과, A, B군의 PMV에 대한 골격 양상과 인구강의 크기는 정상이었다. 2. 두경부 자세비교 1) A, B군의 치료 전후비교에서, A군은 두경부 각도가 상방으로 B군은 두경부 각도와 하악하연이 하방으로 경사됨을 보였다. 2) 세 군간의 치료 전후를 각각 비교한 결과, 치료전에 두경부 각도가 A군은 정상적이었으며, B군은 정상보다 상방 경사짐을 보였다. 치료후에는 A, B군 모두 정상적인 두경부각도를 보였다. 3. 설골 위치 비교 1) A, B군의 치료 전후 비교에서, 두군 공히 설골장축 각도의 변화가 없었고 전후방적으로 A군은 설골이 후방위치되었으며 B군은 변화가 없었다. 수직적으로는 A군의 APHFH가 증가되었을 뿐 나머지 항목에서는 두 군 모두 변화가 없었다. 2) 세 군의 치료 전후를 각각 비교한 결과, 설골장축 각도는 A, B군 모두 정상적이었으며, 전후방적으로 치료전에 A군이 B, C군보다 설골이 전방에 위치되었으나 치료후에는 A, B군 공히 정상적 위치였었다. 설골의 수직적 위치는 치료 전후에 A, B군 모두가 정상적이었다. The present study assessed the effects of Rapid Maxillary Expansion on head posture and hyoid bone position. For this study, 32 Angle's class Ⅲ patients - hellman 3c ~ adult, mean age 12y9m - were selected and divided into two groups, A,B according to craniocervical angulation. Crantiocervical angulation Increased in Group A and decreased in Group B after the therapy. And 23 Angle's class I persons ~ same hellman state, mean age 12y7m ~ were selected for the control group. Cephalometric analysis of skeletal pattern, pharyngeal space, head posture, hyoid bone position was performed. The results were as follows, 1. Comparison of skeletal pattern and pharyngeal space 1) All two group(A,B) had Mandibular plane inclined inferiorly and no pharyngeal space change was observed after RME therapy. 2) Skeletal pattern and pharyngeal space of Group A,B were normal before and after treatment. 2. Comparison of head posture 1) Cranicoervical angulation of Group A was increased after treatment. That of Group B was decreased and mandibular plane was inclined inferiorly after treatment. 2) Before treatment, craniocervical inclination was normal in Group A but larger than normal in Group B. After treatment, all two group(A,B) had normal craniocervical angulation. 3. Comparison of hyoid bone position. 1) After treatment, long axis of hyoid in Group A,B was not changed. Antero-posteriorly, hyoid position was changed posteriorly in Group A but no change was founded in Group B after treatment. Vertically, hyoid bone position were not changed in two groups except in crease in APHFH in Group B after treatment. 2) Long axis of hyoid bone was normal in Group A, B before and after treatment. Anteroposteriorly, hyoid bone positon was more anterior than Group B, C before treatment but all the position of two groups had normal position after treatment. Vertical position of hyoid bone was normal in all two groups before and after treatment.

      • S.D. Rats를 이용 1, 1-Dichloro-1-fluoroethane의 아민성 흡입독성 연구

        김현영,이성배,임철홍,김철우,점용현,한정희,전윤석,최수영,강대봉,이용묵 한국환경독성학회 2002 환경독성보건학회지 Vol.17 No.1

        There were no specific effects for test materials on Sprague-Dawley (S.D.) rats in clinical symptoms, amounts of food intakes, weight changes, laboratory findings, and pathology after whole body l, l-Dichloro-1 -fluoroethane (used as coolant, metal cleaner and solvents) exposure(0, 1,500, 3,000, and 6,000 ppm) for 13 weeks (6 hour/day, 5 days/week). However, the loss of capillary vessels in eyeball (pupil) was observed in a female rat among 6,000 ppm group. Though there was a tendency for MCHC (Mean Corpuscular Hemoglobin Concentration) in rat to be decreased (p<0.05), it was not regarded as abnormal because the values were within normal limits. In asthma-stimulation related evaluations, there was also a tendency for inflammatory cell counts in bronchoalveolar lavages to be increased. But it had no statistical significance, and also no dependency on sex and the exposed concentration. Based on this result, the non observed effect level (NOEL) induced by 1, 1-Dichloro-l -fluoroethene inhalation was evaluated in groups with 3,000 ppm below (S .D. Rats, 13 weeks). Finally, it was concluded that the short term exposal of 1, 1-Dichloro-l-fluoroethane is not considered as a asthma stimulant by inhalation despite of some study limitations such as test animals use and short-term exposure .

      • A case of herpes zoster followed by erythema multiforme

        ( Hyeon Woo Jeon ),( Soo Hyeon Bae ),( Sook Jung Yun ),( Young Ho Won ),( Jee Bum Lee ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1

        Erythema multiforme (EM) is a skin condition considered as a hypersensitivity reaction to infections or drugs. While HSV infection is the most common predisposing factor, the association of herpes zoster (HZ) with EM is rarely reported. Herein, we report a rare case of EM preceded by HZ in a 83-year-old male. The patient with no underlying disease presented with an asymptomatic erythematous targetoid plaques on his entire body, which occurred 5 days prior. He also reported a 2 weeks-history of HZ on his Rt. T7-8 dermatome. Histopathologic findings of erythematous targetoid plaque showed dense and diffuse inflammation from the superficial to deep dermis, which were composed of neutrophils, lymphocytes, histiocytes and eosinophils. Based on clinical findings and histologic features, EM was diagnosed. In addition, we performed polymerase chain reaction (PCR) with the skin tissue specimen of EM lesion. As far as we know, this is the first case of HZ followed by EM in Korean literature. We suggest that physicians should be aware that HZ associated EM may occur simultaneously.

      • P129 Effects of citron essential oils on VEGF, TRPV1, IL-8 release from normal human epidermal keratinocytes stimulated with TNFα

        ( Hyeon Woo Jeon ),( Soo Hyeon Bae ),( Sook Jung Yun ),( Seung-chul Lee ),( Jee-bum Lee ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.2

        <div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div> Background: Citron is well-known for it’s abundant antioxidative ingredients such as vitamin C, polyphenol compounds, and limonoids. Objectives: We aimed to evaluate the anti-oxidant and anti-inflammatory activities of citron essential oils on the activated keratinocytes in vitro. Methods: We used normal human epidermal keratinocytes (NHEKs) derived from neonatal foreskin. In order to evaluate the antioxidant activities of citron, DPPH radical scavenging activity, intra- and extracellular ROS generation and expressions of anti-oxidant enzymes (HO-1, Prx-1, CAT, SOD-2; Mn-SOD) were analyzed. Also, to evaluate the anti-inflammatory activity of citron essential oils on epidermal cells, NHEKs were stimulated with TNFα and vascular endothelial growth factor (VEGF), transient receptor potential vanilloid 1 (TRPV1), IL-8 were induced. These mediators were analyzed after treatment of citron seed and unripe citron oils, and also EGCG as a control. The analysis was performed by semi-quantitative RT-PCR, immunocytofluorescence and ELISA. Results: mRNA and protein levels of VEGF, TRPV1, and IL-8 of activated keratinocytes were suppressed by citron seed and unripe citron oils. Conclusion: These results show that citron essential oils possess both anti-inflammatory and anti-angiogenic properties, which indicate that this agent may be a valuable adjuvant treatment candidate for rosacea.

      • SCIESCOPUSKCI등재

        Thermal Fatigue - Resistant EMCs(Epoxy Molding Compounds) for Microelectronic Encapsulation

        Bae, Jong Woo,Kim, Won Ho,Cho, Suk Hyeon,Hong, Yong Woo,Shin, Jung Eun,Lee, Sang Hyun 한국화학공학회 2000 Korean Journal of Chemical Engineering Vol.17 No.1

        Highly thermal conductive EMCs (Epoxy Molding Compounds) should be considered for the alleviation of thermal stress-related problems caused by low thermal conductivity, and high elastic modulus of EMCs and by a mismatch of CTE (Coefficient of Thermal Expansion) between EMCs and the Si-wafer. Compared to crystalline silica-filled EMCs, alumina filled EMC improved the value of thermal conductivity by 100% and lowered the value of CTE by 50%. As a result, compared to typical crystalline silica-filled EMCs, the thermal fatigue resistance of alumina-filled EMC was improved by sixfold.

      • 퍼지 논리와 신경망에 기반한 공정 예측 및 품질 추정을 위한 공정관리 의사지원시스템

        배현(Hyeon Bae),우영광(Young-Kwang Woo),김성신(Sungshin Kim),우광방(Kwang-Bang Woo) 한국지능시스템학회 2004 한국지능시스템학회 학술발표 논문집 Vol.14 No.1

        차세대 생산 시스템(Next Generation Manufacturing System: NGMS)의 핵심 개념은 분산 생산 시스템과 다품종 소량의 유연 생산 시스템의 지원이다. 이러한 시스템의 구성을 위하여 실시간 데이터에 기반한 예측 모델이 필수적인데, 이러한 예측 기능을 통하여 생산공정의 관리와 운영, 특히 전체 공정관리를 효율적으로 수행할 수 있다. 한편, 공정으로부터 전송된 데이터는 특정한 형태의 지식으로 표현된다. 이러한 지식들은 시스템에 대한 다양한 정보를 가지고 있으므로 정보를 이용하여 시스템 상태를 빠르고 쉽게 진단할 수 있다. 공정 진단은 현재 공정 상태에서 생산되는 제품의 품질을 추정할 수 있는 정보로 활용된다. 본 논문에서는 이러한 개념이 바탕이 되어 공정관리 시스템을 설계하였다. 제안된 시스템의 적용 대상은 반도체 제조 공정의 단위 공정인 에칭 공정이다. 애칭 공정은 공정 중에 연속적인 검사가 수행되지 않고 최종 제품에 대한 검사가 수행되므로 불량 원인을 찾는 것이 쉽지 않다. 따라서 본 논문에서는 공정관리를 위한 의사지원시스템을 통해 공정의 연속적인 간접진단을 수행하고자 하였다. 본 연구에서 사용된 의사지원시스템은 각 공정에서 얻어지는 데이터와 경험적 지식을 토대로 공정시스템의 해석과 진단이 가능한 시스템이다.

      • Impact of Current Latent Tuberculosis Infection Strategy - Screening Individuals with Medical Risk Factors for Tuberculosis

        ( Hyung Woo Kim ),( Ju Sang Kim ),( Jinsoo Min ),( Ah Young Shin ),( Joon Young Choi ),( Jun-pyo Myong ),( Yunhee Lee ),( Hyeon Woo Yim ),( Hyunsuk Jeong ),( Sanghyuk Bae ),( Ji Young Kang ),( Hyeon-k 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.-

        Background This study aims to estimate the impact of current latent tuberculosis infection screening (LTBI) strategy - screening individuals with medical risk factors for tuberculosis (TB). Methods 8 prevalent cohorts extracted from National Health Information Database including individuals who had disease with high or moderate TB risk specified in Korean guidelines for TB at the timepoint of January 1st, 2018 were followed up for a year by matching with nationwide notified TB cases in 2018. Standardized incidence ratio (SIR) of TB was calculated in each cohort by comparing with nationwide TB incidence after stratification by age and sex. The proportion of TB cases from each cohort among nationwide TB cases notified in 2018 was also investigated. Results A total of 19,856 patients with human immunodeficiency virus, 63,003 patients in post-organ transplantation status, 36,946 patients who underwent tumor necrosis factor antagonist treatment, 130,885 patients with end-stage renal disease, 253,585 patients in post-gastrectomy status, 65,647 patients with head or neck malignancy, 127,850 patients with hematologic malignancy and 3,721,100 patients with diabetes mellitus (DM) were identified. SIR of TB in each cohort was 6.63 (95% confidence interval, 5.47-8.04), 3.26 (2.76-3.86), 4.97 (4.13-5.99), 2.73 (2.52-2.96), 1.60 (1.48-1.73), 1.68 (1.46-1.93), 2.05 (1.85- 2.28) and 1.30 (1.27-1.33), respectively. Among 33,795 nationwide TB cases notified in 2018, the number of patients from each cohort was 103 (0.3%), 134 (0.4%), 111 (0.3%), 601 (1.8%), 594 (1.8%), 190 (0.6%), 348 (1.0%) and 6,835 (20.2%), respectively. Patients who had disease with high or moderate TB risk accounted for 30.6% (4,677 / 15,281) of TB cases in elderly population aged 65 or over. Without patients from the DM cohort, the proportion had decreased into 7.0% (1,063 / 15,281). Conclusions Impact of current LTBI strategy focusing on medical high-risk group is limited. Further high-risk groups should be identified.

      • 국내 강낭콩 유전자원의 작물학적 특성

        배진우 ( Jin Woo Bae ),박현진 ( Hyeon Jin Park ),장윤우 ( Yun Woo Jang ),한원영 ( Won Young Han ),고종민 ( Jong Min Ko ),강항원 ( Hang Won Kang ),신상욱 ( Sang Ouk Shin ),이병원 ( Byung Won Lee ),백인열 ( In Youl Baek ) 한국콩연구회 2015 韓國콩硏究會誌 Vol.32 No.1

        The purpose of this study was to provide information of breeding kidney bean (Phaseolus vulgaris L.) by investigating the characteristics of 211 germplasm collected in Korea. In most of germplasm (51.9%) it took 46∼50 days from sowing to flowering and in the others (29.0%) it took 51∼55 days. From flowering to maturity, it took 36∼40 days (21.2%), 41∼45 days (60.2%), 46∼50 days (11.1%). Total growth period was 91 to 95 days (89.3%). The plant types was classified as determinate (73.9%), indeterminate (24.2%) and intermediate (1.4%). The kidney bean flower was consists of banner and wing, and banner color was devided into three types; white (18.9%), pink (51.0%) and purple (30.1%) and wing color were white (18.4%), pink (71.4%) and purple (10.2%). Average pod length was 10.0∼14.9㎝ (77.3%) and pod width was 1.10∼1.29㎝ (48.3%). The color of seed coat was reddish purple (57.7%). Second seed coat color does not have a majority (73.7%), most of the germplasm did not contain the second seed coat color, but 26.3% showed different coat color. 100 seed weight for 65.2% of germplasm was 40.0∼59.9g.

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