韓國人에서 多重增幅 重合酵素反應으로 分析한 STRs 遺傳座位의 遺傳的 多樣性

권국환,이혜린,박종진,황적준,이희석,송은섭 大韓法醫學會 1996 대한법의학회지 Vol.20 No.1

The tetrameric STRs loci were studied in a population of Korean(n=223) for allele frequency distribution and applicability to identity and paternity testing, using multiplex PCR with electrophoresis of the PCR products in DNA sequencing gels and subsequent detection of allelic fragments by silver staining. The STRs loci analyzed were HUMCSF1PO, HUMTPOX, and HUMTHO1 ; in the Korean population, 9 alleles with their frequency range of 0.002-0.363 are detected in the HUMCSF1PO, 5 alleles with those of 0.020-1.480 in the HUMTPOX, and 6 alleles with those of 0.002-0.489 in the HUMTHO1. The highest observed heterozygosity is found at the locus HUMCSF1PO(0.709), those of the loci HUMTPOX and HUMTHO1 being 0.646 and 0.632, respectively. All loci meet Hardy-Weinberg expectations ; there are good agreement between the observed and expected values under Hardy-Weinberg equilibrium. Moreover, pairwise comparisons between loci show allelic independence for all the 3 loci comparisons. The power of discrimination (PD) determined for the locus HUMCSF1PO is 0.8896 (88.96%), that of the HUMTPOX is 0.8818(88.18%), and that for the HUMTHO1 is 0.8367(83.67%) ; the combined power of discrimination for the triplex is 0.9976(99.76%). The power of exclusion(PEX) calculated for the loci HUMCSF1PO, HUMTPOX, and HUMTHO1, being prior probability that a falsely accused father will be excluded, and 0.5173(51.73%), 0.4610(46.10%), and 0.5101(510.01%), respectively, and the cummulative power of exclusion(CPE) for all the three loci is 0.8726(87.26%). Thus, these allelic frequency data can be used to construct the database of the multiplex PCR-based DNA profile in the Korean population. The calculated parameter, "power of discrimination(PD)" and "power of exclusion(PEX)", show the informativeness of these loci for the determination of identity and relatedness of individuals.

학령중기 남아의 상지동작에 따른 상반신 체표변화 연구

김미영,여혜린,권영숙 한국의류산업학회 2002 한국의류산업학회지 Vol.4 No.2

This study was to provide the fundamental data for a scientific and rational clothing construction by investigating the variation of the upper body surface with the use of the method of Surgical tape. The subject were 3 middle elementary schoolboys classified standard somatotype, and arm-movements were consisted of 6 types. The statistical analyses used in this study were mean, standard deviation and the ANOVA and LSD procedure. Shoulder point was moved to be the inside or upside and the shape of the armhole-line was differently changed as the arm-movement become larger. By moving to upside of the anterior armpit point, posterior armpit point and armpit point, the increase of the side seam length and the ascent of the line of width between armpits were distinct. And by arm-movements, in the items of horizontal, front neck base girth, back upper bust girth, back bust girth and back waist girth were increased and the other standard lines were apt to be decreased. In the items of vertical, all standard lines of front side and side seam length showed increased, back waist length and back length showed decreased. The variation of armhole was indefinite. In the rate of the variation, the shoulder length showed the maximum rate of contraction by 41.3%, decreasing 3.7㎝ in 180° degrees, and the side seam length showed the maximum rate of expansion by 60.6%, increasing 8.97 cm in the same degrees.

A Study on Occupational Stress and Coping, Turnover, Knowledge and Practice of Infection Control in Dental Hygienists of COVID-19

( Hye-rin Kwon ),( A-young Gil ),( Ji-min Kim ),( Ji-seon No ),( Ga-bin Park ),( Ji-yune Oh ),( Na-kyung Lee ),( Seol-hee Kim ) 한국치위생과학회 2021 치위생과학회지 Vol.21 No.4

Background: The importance of infection with COVID-19 is being emphasized in dentistry with high risks such as aerosols. The purpose of this study is to investigate the knowledge and practice of infection control, stress and coping, and turnover of dental hygienists. Methods: Questionnaire was conducted knowledge and practice of infection control, occupational stress and coping, turnover. Survey data was investigated about 149 dental hygienists from February to March 2021 Data were analyzed t-test, ANOVA, Pearson’s correlation using statistical programs of PASW Statistics ver. 21.0. Results: Regarding occupational stress, relationship conflict was higher in the group with less than 2 years of experience (p<0.05). Job anxiety, organizational system, inadequate compensation, and workplace culture were highly surveyed in the 3 to 5 year of experience. The group with more than 6 years of experience had the highest perception of lack of job autonomy (p<0.05). The group with higher knowledge of infection control had lower mean inappropriate rewards and stress (p<0.05). The group with high infection control performance had a lower average in items such as job instability, organizational system, inadequate compensation, workplace culture, and stress. And problem-focused coping ability was found to be high (p<0.05). Infection control knowledge and performance were positively correlated (r=0.251, p<0.01), infection control practice and stress were negatively correlated (r=-0.264, p<0.01), and stress and emotional coping were positively correlated (r=0.367, p<0.01). Stress was positively correlated with turnover rate (r=0.549, p<0.01). Conclusion: Infection control training was required to reduce occupational stress. Occupational stress was highly correlated with turnover, a holistic and systemic organizational operation and improvement of the quality of medical care were required to reduce stress.

물성특성에 의한 현대건축 외피의 표현유형 연구

권혜린(Kwon, Hye Rin),김현중(Kim, Hyun Joong) 한국디자인문화학회 2017 한국디자인문화학회지 Vol.23 No.2

건축외피는 도시변화에 민감한 패러다임적 요소로써현대건축의 외피는 근대와는 명확히 다른 양상을 보인다. 현대건축의 복합적 외피는 단순한 이차원적면이 아닌 인간의 지각을 확장하고 행위를 창출하는 ‘경계공간’으로 이해되고 있다. 따라서 본 연구의 범위를 건축외피에 한정하고, 통시적으로 변화해온 외피의 ‘물질적 표현’에 집중하였다. 즉, 건축외피를 통해 한 시대를 대표하는 표상을 이해하고 잠재된 재료의 가치를 발견하는 것을 목표로 하였다. 문헌을 통해, 근대건축사의 이해 속에서 변화된 외피의 역할을 탐구하였고 현대에서 나타나는 건축외피의 표현양상을 도출할 수 있었다. 현대에서는 재료의 비물질화가 외피를 통해 나타났고, 이 ‘비물질화’를 이해하고자 재료의 물질과 물성적 표현에 대해 탐구하였다. 또한 외피의 물질표현에 집중한 건축가들의 건축물을 사례로 선정하여 분석하였고 반복적으로 나타나는 각 표현유형을 ‘상실’, ‘생성’, ‘초월’로 정의하였다. 사례 분석을 통해 외피의 비물질성표현은 물성의 감성적 표현으로 건축과 인간의 조화를 매개한다는 결론을 내릴 수 있었다. 즉, 현대건축외피의 물질적 표현은 도시의 총체적 구성요소를 외피에 함축적으로 표현하여 인간의 지각을 자극하고 확장하는 것이다. 하지만 최근의 건축외피는 주변 환경과 분리되어 단독의 이미지처럼 평면에 고착되어있다. 오늘날의 외피에 대한 패러다임을 부정하는 것은 아니지만, 외피를 포함한 현대건축공간은 도시와 상보적인 관점에서 시대를 표현해야한다. 이러한 의미에서 건축 재료가 지닌 부가가치의 다양성 연구와 실험은 현시대를 담은 성숙한 공간표현의 플랫폼 역할이 될 것이다. The surface of contemporary architecture is clearly different from that of modern architecture. The surface of architecture is defined as paradigmatic element that is sensitive to city change and is understood as ‘boundary space’ by extending perception and creating further action of human. Therefore, the goal of this research is to focus on the surface of architecture that has changed over time to find out the potential value of material and to understand the representative symbol which symbolizes an era of the architecture. Through the literature, I examined the role of changed surface in the understanding of modern architecture, and was able to elaborate presentation aspect that surface of contemporary architecture presents. The non-materialization has appeared through the surface in the modern time and its matter and materiality of materials were examined by many studies in order to understand non-materialization. In addition, I was able to define expression as ‘loss’, ‘creation’ and ‘transcendence’ after observing repetitive expression patterns from specific architectures of architects who focus on matter expression of surface. From case analysis, we drew a conclusion that immateriality expression of surface harmonizes human and architecture with emotional expression of matter. In other words, matter expression of contemporary architecture stimulates and expands human’s perception by implicitly expressing every components of the city through the surface. However, surface of recent architecture is now separated from its surrounding environment and limits itself on a plane like an unilateral image. It does not mean that I disagree with today’s paradigm of architecture surface but it should express images of our time with both contemporary architecture and the city in a complementary relation. The variety experiments and studies with their valuable and potential materials will become important roles that play the platform of spatial expression in mature contemporary architecture that we live in.

특집 : 지방화시대의 문화정책과 그 혁신방안 ; 거창군(居昌郡) 문화정책 사례발표 -거창국제연극제를 중심으로-

권혜린 ( Hye Rin Kwon ) 경북대학교 영남문화연구원 2004 嶺南學 Vol.- No.5

Human placental extract exerts hair growth-promoting effects through the GSK-3β signaling pathway in human dermal papilla cells

KWON, TAE-RIN,OH, CHANG TAEK,CHOI, EUN JA,PARK, HYE MIN,HAN, HAE JUNG,JI, HYI JEONG,KIM, BEOM JOON UNKNOWN 2015 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE Vol.36 No.4

Effect of total phospholipid fraction on cutaneous pressure ulcer

( Hye Sung Han ),( Ji Yeon Hong ),( Tae Rin Kwon ),( Kui Young Park ),( Kapsok Li ),( Beom Joon Kim ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.2

Background: Recently various dressing materials and techniques have been developed for treatment of cutaneous pressure ulcer. The total phospholipid fraction (TPF) is a phospholipid fraction extracted from porcine lung tissue. TPF is a novel candidate dressing material for cutaneous pressure ulcer. Objectives: This study aimed to evaluate the efficacy of total phospholipid fraction (TPF) on cutaneous pressure ulcer using the mouse model. Methods: In total, 10 Female C57BL/6 mice were randomized into 5 groups of 2 mice each: healthy control, control, silver sulfadiazine, 1% TPF and 2% TPF. Magnet plate ischemia/reperfusion model was used to form pressure ulcer. A twice-daily dressing using each dressing material was performed for 3 weeks. Digital camera, punch biopsy, special stain, immunohistochemistry, immunoblot assay and real-time PCR were performed to evaluate wound healing in each group. Results: We observed that TPF inhibit infiltration of mast cell, neutrophil, macrophage infiltration, pro-inflammatory cytokines and chemokines. Moreover, TPF attenuated cell apoptosis and skin injury but accelerated angiogenesis, collagen synthesis, keratinocyte differentiation, promoting dermal reconstruction and improving skin barrier. Conclusion: The results of this study suggest that TPF can be expected as a novel potent agent for treatment of cutaneous pressure ulcer.

여대생의 라이프 스타일과 스페셜티 스토어 이용실태에 관한 연구

권미린,박정화,백진이,안계환,안자영,오해정,현혜선 연세대학교 생활과학대학 1988 婦學 Vol.21 No.-

The purpose of this study was to find life styles and shopping trends at specialty store of college women students. Findings indicated that demographic variables such as economic and grade level were significantly related to shipping trends at specialty store.

Phylogenetic classification of metallothionein gene screened from RNA-Seq database of shell-less land slug Incilaria fruhstorferi

Hye Rin Min,Se Won Kang,Hee-Ju Hwang,Jong Min Chung,Dae Kwon Song,Min Kyu Sang,Ji Eun Park,Hee Cheol Ha,Hyun Jun Lee,Chan Eui Hong,Hong Seog Park,Yeon Soo Han,Jun Sang Lee,Yong Seok Lee 한국수산해양기술학회(구 한국어업기술학회) 2016 한국수산해양기술학회 학술발표대회 Vol.2016 No.10

Phylogenetic classification of metallothionein gene screened from RNA-Seq database of shell-less land slug Incilaria fruhstorferi

Hye Rin Min,Se Won Kang,Hee-Ju Hwang,Jong Min Chung,Dae Kwon Song,Min Kyu Sang,Ji Eun Park,Hee Cheol Ha,Hyun Jun Lee,Chan Eui Hong,Hong Seog Park,Yeon Soo Han,Jun Sang Lee,Yong Seok Lee 한국수산과학회 양식분과 2016 한국수산과학회 양식분과 학술대회 Vol.2016 No.10