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조영호(Young Ho Cho),안계환(Ghe Whan Ahn),양승원(Seung Won Yang),조관현(Kwan Hyun Cho),김상원(Sang Won Kim),백명기(Ki Myoung Baek),이계원(Gye Won Lee) 한국생물공학회 2011 KSBB Journal Vol.26 No.6
Psolarea corylifolia extract that contains bakuchiol is known to have anti-microbial, anti-inflammatory and anti-scarring effects. In this study, a vesicles such as liposome, niosome, and transfersome were produced to encapsulate P. corylifolia extract and measured their stability and physiochemical property. The skin permeation and partitioning of P. corylifolia extract in the vesicles were elucidated in nude mouse skin by using Franz diffusion cells after topical application for 24 h. After storage at 25, 40, 70℃, and light, the stability of bakuchiol incorporated into the vesicles was maintained for 30 days. The optimal concentration of P. corylifolia extract entrapped into the vesicles was found to be 5~10%. From the physicochemical studies, after storage at 4, 25, and 40℃, the viscosity and particle size of the vesicles remained in 30~80 cP and the nanosize range for 6 months, respectively. From the permeation experiments, niosome showed a higher amount of bakuchiol permeated through the mouse skin compared to liposome and transfersome after 24 h. From these results, niosome and transfersome could be a good bioavailability enhancement system (BAES) for P. corylifolia extract to improve the skin permeation and stability.
여대생의 라이프 스타일과 스페셜티 스토어 이용실태에 관한 연구
권미린,박정화,백진이,안계환,안자영,오해정,현혜선 연세대학교 생활과학대학 1988 婦學 Vol.21 No.-
The purpose of this study was to find life styles and shopping trends at specialty store of college women students. Findings indicated that demographic variables such as economic and grade level were significantly related to shipping trends at specialty store.