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남궁기,이호영,노재성 大韓神經精神醫學會 1991 신경정신의학 Vol.30 No.1
A single stage random cluster sampling was conducted and 1,450 samples were selected from Kangwha Island. A psychiatric epidemiologic survey was done using Korean version of NIMH-Diagnostic Intervies Schedule. Sociodemographic characteristics, natural course, and frequencies of DIS alcoholic symptoms were compared among alcohol dependence, alcohol abuse and non-alcoholic groups. The results were as follows; 1) In comparison of sociodemographic characteristics between alcohol dependence and alcohol abuse group, marital status and age distribution showed significant differences but there were no significant differences in sex and occupation between two groups. 2) There were no significant differences in mean age of first heavy drinking episode and onset of symptoms in alcohol abuse and alcohol dependence group. 3) Mean duration of alcohol use disorder was significantly different between alcohol dependence and alcohol abuse group(13.5±12.2 years and 9.2±10.8 years). And it was also significantly different between male alcohol dependence and male alcohol abuse group(13.1±11.9 years and 9.2±10.7 years). 4) The latency period of alcohol use disorder in alcohol abuse and alcohol dependence group were 7.0±10.3 years and 8.7±10.1 years in each, which was not significantly different and in comparison of latency period in only male, there was no significant difference between two groups(7.3±10.4 years and 9.5±9.4 years). 5) In comparison of frequencies of alcoholic symptoms between alcohol dependence and alcohol abuse group, frequencies of symptoms such as `think oneself as a excessive drinker', `bender at least two days', `continue to drink even with serious physical illness' were significantly higher in alcohol dependence group. 6) In comparison of prevalence of medical complications between alcohol dependence and alcohol abuse group, prevalence of peripheral neuropathy, stomach disease, liver disease and memory impairment were significantly higher in alcohol dependence group.
한국 일 농촌지역(강화도) 노인 주정 중독의 역학적 연구
남궁기,이호영,이만홍,신승철,김병후 大韓神經精神醫學會 1989 신경정신의학 Vol.28 No.6
An epidemiological study of alcoholism in the elderly was done in Kangwha in 1987. The results are as follows: 1) The lifetime prevalence rate of alcoholism in elderly is 21.2%, which consists of 16.6% of alcohol abuse and 4.6% of alcohol dependency. 2) The lifetime prevalence rate of elderly alcoholism in male is about 7 times higher than in female(41.5% vs 6.6%). 3) Age-specific prevalence rate of elderly alcoholism decreases with age. 4) The lifetime prevalence rate of elderly alcoholism is significantly high in unmarried group and educated group, compared to those in married group and uneducated group (39.3% vs 4.4%, 41.6% vs 15.2%) 5) When elderly alcoholism is classified into 4 types by its onset and course, the rate of early-onset type(onset before 40 years old) is 72,6%. 6) The prevalence rate of other psychiatric disorders do not show any significant difference between alcoholic group and non-alcoholic group, but the prevalence rate of mild cognitive impairment in alcoholic group is significantly lower than that in non-alcoholic group) 12.5% vs 36,6%). 7) The 5 dimensional scores of social resources, economic resources, mental health, physical health and activities of daily functions do not show any significant differences between alcoholic group and non-alcoholic group.
Precancerous Conditions of Uterine Cervix and its Relation to Trichomonal Infection
Namkoong, Sung Eun,Kim, Seung Jo,Lee, Yong Seon,Kim, Yoon Ho,Kim, Sun Moo CATHOLIC MEDICAL CENTER 1979 Bulletin of the Clinical Research Institute Vol.7 No.1
Trichomonas Vaginalis, first described by Donne, 1836, for many years has been associated with lesions of the female genital tract.
강화도 정신과 역학 연구(Ⅱ) : 연구설계 Survey Design
남궁기,오희철,유승흠,이만홍,민성길,이호영,김일순,Yu, Elena 大韓神經精神醫學會 1989 신경정신의학 Vol.28 No.6
The Kangwha Psychiatric Epidemiologic Survey was done as the first step of Kangwha Health Project. Summary of the survey design were as follows. 1) 2195 subjects were selected by single stage random cluster sampling. 2) As a survey instrument the Korea version of NIMH-Diagnostic Interview Schedule were used, which was verified with a validity test by the present authors. 3) 30 lay-interviewers who were high school graduates or college students were trained for two weeks and 26 of them conducted home visiting survey for one month. 4) Out of total 2195 selected subjects, 1450 subjects were interviewed completely, thus the completion rate was 66.10%. 5) Data was sent to and analyzed in the University of Texas with DIS-Program which had been developed in Wasington University.
남궁기,이희상,전종호,현명호,천덕희,유계준 大韓神經精神醫學會 1996 신경정신의학 Vol.35 No.3
충동성과 스트레스는 주정 의존의 원인, 증상 혹은 위험 요인이나 재발 요인으로서 논란의 대상이 되고 있으나, 현재까지 국내에서는 이에 관한 연구가 없다. 따라서 만일 주정 의존의 원인 및 재발 요인으로 생각되는 충동성과 스트레스 내인력이 주정 의존 환자군과 대조군 사이에 의미 있는 차이가 나타난다면 주정 의존의 치료에 있어서도 충동성을 낮추고 스트레스 내인력을 증가시키는데 초점을 두는 새로운 사회 기술 훈련 방법 등을 고안 적용함으로써, 보다 효과적인 치료를 제공할 수 있을 것으로 생각된다. 이러한 배경에서 본 연구가 계획되었다. 이에 본 연구의 목적은 국내 주정 의존 환자군을 대상으로 하여 주정 의존 환자군은 대조군에 비해 충동성의 경향이 유의하게 높을 것이고, 스트레스 내인력이 유의하게 떨어질 것이라는 가설을 검정하므로써, 주정 의존군과 대조군 사이에서 충동성과 스트레스 내인력에 어떤 차이가 있는 지를 알아보는 것이다. 본 연구에서는 29명의 주정 의존 환자군과 29명의 대조군을 연구 대상으로 하였다. 충동성을 측정하기 위해서 충동성 척도(impulsivity scale)와 인식력 검사(Cognitrone test)를 사용하였다. 연구 결과 충동성 척도 검사에서 주정 의존군은 전체 충동성 및 무계획 충동성과 운동 충동성이 대조군에 비해 통계적으로 유의하게 높았다(p<0.05). 인식력 검사에서는 주정 의존군이 대조군에 비해 틀린 문항 수가 통계적으로 유의하게 많았는데(p<0.05) 이는 주정 의존군의 충동성이 높음을 시사한다. 운동 결정력 검사의 소검사-3에서 주정의존군이 대조군에 비해 시간 내에 반응한 옳은 반응의 수가 통계적으로 유의하게 적었으며(p<0.05), 이는 주정 의존군의 스트레스 내인력이 떨어짐을 시사한다. 이러한 본 연구의 결과는 주정 의존 환자가 정상인에 비해 충동성이 높고, 스트레스 내인력이 떨어진다는 기존의 연구 결과들과 일치한다. 이러한 결과들을 통해 볼 때 주정 의존 환자의 치료와 예후의 판단 및 치료 효과의 평가에 충동성과 스트레스 내인력을 그 지표로 사용할 수 있을 것이다. This study was attempted to make a comparison of the impulsivity and the stress tolerance between patients with alcohol dependence(alcoholic group) and control subjects(control group). The author examined 29 alcoholics and 29 control subjects by the impulsivity scale, Cognitrone test and Determination Unit test. The results were summarized as follows : The scores of IMPM(impulsivity-motor), IMPP(impulsivity-nonplanning) and IMP(impulsivity-total score) were significantly higher in alcoholic group than in control group(10.00±5.43 vs 6.38±4.84, t=2.56, d.f.=51, p<0.05 ; 15.22±6.68 vs 10.77±5.87, t=2.53, d.f.=51 p<0.05 ; 36.67±13.20 vs 27.12±11.73, t=2.78, d.f.=51, p<0.05). The number of incorrect responses(Incorrect) of the Cognitrone test was significantly higher in alcoholic group than in control group(25.52±13.26 vs 17.83±7.30, t=2.47, d.f.=43.53, p<0.05 in Student t-test). The number of timely right responses of the Determination Unit test, subset-3 was significantly lower in alcoholic group than in control group(62.79±43.13 vs 90.79±52.02, t=-2.23, d.f.=56, p<0.05 in Student t-test). These results mean that the impulsivity is higher and the stress tolerance is lower in alcoholic group than in control group. With these results, the impulsivity and the stress tolerance in alcoholic patients can be used as indicator of their treatment efficacy and prognosis.
Polymorphism of Coagulation Factor XIIIA and XIIIB Subunits of Plasma in Korean Population
NamKoong, Yong,Lee, Chung Choo,Hong, Seung Ho,Kim, Hyun Sup,Lee, Kyung Lyong 한국유전학회 1989 Genes & Genomics Vol.11 No.4
As a part of researches for identifying the genetic composition of Korean population, authors have studied the phenotypes and allele frequencies of Coagulation Factor XIIIA (FXIIIA) and Coagulation Factor XIIIB (FXIIIB) in the plasma of Korean using agarose gel isoelectric focusing followed by immunoblotting. In the study of 329 individuals of Seoul, Kangreung and Kwangju, the identified phenotypes of FXIIIA were FXIIIA 1 (75.99%), FXIIIA 2-1 (23.40%) and FXIIIA 2 (0.61%). The allele frequencies of FXIIIA^*1 and FXIIIA^*2 were 0.8769 and 0.1231, respectively. And the phenotypes of FXIIIB were FXIIIB 1 (8.6%), FXIIIB 3 (46.9%), FXIIIB 3-1 (41.0%) and FXIIIB 3-2 (3.4%). Allele frequencies of FXIIIB^*1, FXIIIB^*2 and FXIIIB^*3 were calculated to be 0.2914, 0.0172 and 0.6914, respectively. The frequencies of FXIIIA^*1 and FXIIIA^*3 in Whites was slightly higher in Blacks, but that in Korean people were much higher than that in Blacks and Whites.