한국 재래산양에서 Bovine Viral Diarrhea, Bovine Herpesvirus-1, Parainfluenza Type-3 바이러스에 대한 혈청학적 연구

한동운,권용국,문진산,윤소라,위성환,장환,탁동섭,이태욱,강문일 한국수의공중보건학회 2003 예방수의학회지 Vol.27 No.3

The 948 goat sera were serologically tested for ten pathogens including bovine viral diarrhea (BVD), bovine herpes virus type-1 (BHV-1) and parainfluenza virus type-3 (PI-3). By viral neutralizaion test, three pathogens including BVD virus, BHV-1, PI-3 were applied for screening each neutralizing antibody and its titration. Among 948 sera, there were 215 seropositives (22.7%) against BVD virus, 25 (2.6%) against BHV-1 virus, and 161 (17.0%) against PI-3 virus, respectively. In the seropositive cases to BVD virus, provincial prevalence of them were recorded as Gyeongnam(30.8%) for the highest one, while as Jeonbuk (15.8%) and Gyeongbuk(l6.7%) relatively for the lower ones. Among them, higher than 1:8 in antibody titration was classified as 74 cases (34.4%) which were suspected the cycle of its infection in their herds. Among the seropositives to BHV-1, it was relatively lower prevalence rate ranging from 1.7% to 6.7% that those of BVD virus and PI-3, but more importantly they were prevailing across the country. Most of the seropositive cases (42.9%) to PI-3 were classified as 1:4-1:16 in titration, but also distributed all around the country. The prevalence in goats varied according to areas (15.8 to 30.8%). Related to the provincial prevalence of three viral agents in Korean goats, it seemed that three viral pathogens would be directly or indirectly involving in various disorders as primary or secondary causative agents resulting in decreased productivity.

한국 재래 산양에서 Leptospira spp.에 대한 혈청역학적 연구

한동운,권용국,문진산,윤소라,위성환,장환,탁동섭,이태욱,강문일 한국수의공중보건학회 2003 예방수의학회지 Vol.27 No.3

Between January 1999 and September 2001, 948 sera (120 from each province except 108 from Chungbuk) from 8 provinces were sampled from Korean goats. All the samples were serologically tested for Leptospira spp. By the microscopic agglutination test against four L. interrogans serovars including canicola, icterohaemorrhagiae, pomona and hardjo, 948 Korean goats were confirmed as 11 seropositives (1.2%) only infected with L. icterohemorrhagiae. All positive sera were collected from Gyeonggi (5), Gangwon (4) and Chungbuk (2). Titration of them were classified as 1:100 of 10 sera except one case with 1:200 from Gyeonggi. It was meaningful that the pathogen in Korean goats was mainly distributed in the northen part of the country. Consequently, the results in the study were confirmed and analyzed the recent status of infection of leptospirosisas zoonotic agentsome in Korean goats.

규칙적인 유산소성 운동이 비만아동들의 신체구성 및 호흡순환기능에 미치는 영향

김태운,신군수,김종인,이광무,김성헌,안병철,고기준,한재웅,이재규 釜山大學校 附設 體育科學硏究所 1997 體育科學硏究所 論文集 Vol.13 No.-

The purpose of this study was to examined the effect of supervised regulary aerobic exercise program with cardiorespiratory function of obese children. The subjects were 16 obese Childrens(elementary school 4∼5 grade), and engaged in regulary aerobic exercise program for 9 weeks(5 days/week, 100 min/day, 60∼70% HRmax) with mountain climbing, basketball and football. The items of cardiorespiratory function measured VEmax, HRmax, RQmax, VCO₂max, VCO₂max, VCO₂max/kg and BFmax after treadmill exercise load. The conclusion of this study was as follows ; 1. In body composition, there were significant decrease(P<0.001) after aerobic exercise for 9 weeks in body weight, percent body mass index 2. In cardiorespiratory function, there were significant increase(P<0.001) after aerobic exercise for 9 weeks in VEmax and VCO₂max by treadmill exercise load. 3. In cardiorespiratory function, there were significant increase(P<0.001) after aerobic exercise for 9 weeks in VO₂mex and RQmax by treadmill exercise load. 4. In cardiorespiratory function, there were significant increase(P<0.001, P< 0.01) after aerobic exercise for 9 weeks in VO₂max/kg and BFmax by treadmill exercise load.

농촌지역 주민의 농기계에 의한 손상에 관한 연구

양한설,이태용,이동배,조영채,심운택 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2

To find out the incidence rate of farm machinery injuries for rural residents and to analyse characterisitics of injuries, we surveyed 10,075 rural residents from six Myons in Chungnam province from January 1, 1990 to Deccember 31, 1990 The results were as follows: 1. 94.4%(101 persons) of the injured were male; 5.6%(6 persons) female. 2. The annual incidence rate per 1,000 rural residents was 10.6 persons, and the annual incidence rate per 100 farm machines was 11.2 persons. 3. The number of the injured were more in mountainous district than in plain distict 4. Injuries were occured throughout the year but predominantly in April and October. Farm machines which caused accidents were power tillers, combine, and a farm tractor in that order of frequency. 5. The injured part of body were fingers and arms, foot and legs, the chest, and the waist in that order of frequency. 6. Most of the injured had been to medical institution for treatment. 7. The major cause of injuries was personal factor.

-G308A Tumor Necrosis Factor-α 유전자 다형성과 주요 우울장애의 연합연구

배치운,오해정,채정호,박원명,전태연,한훈,김광수 大韓神經精神醫學會 2003 신경정신의학 Vol.42 No.2

Objectives : The present study was to examine possible association between the - G308A tumor necrosis factor (TNF)-α gene polymorphism and major depressive disorder (MDD) in Korean. Methods : 108 inpatients with MDD and 125 healthy controls participated in this study. Genotyping was performed by polymerase chain reaction-restriction fragment length polymorphism. Results : Genotype and allele distributions in patients with MDD (p=0.02, P=0.01, respectively), were significantly different from those of the controls. Conclusion : The present study suggests that the -G308A TNF-α gene polymorphism may have a potential role for the susceptibility to MDD in Korean population.

주요 우울장애에서 Cytotoxic T Lynphocyte Antigen(CTLA-4) 유전자의 다형성

전태연,배치운,김병균,채정호,박원명,김광수,유태열,한훈 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.5

연구목적 : 세포의 면역 기능 조절에 관여하는 CTLA-4의 유전자 다형성을 분석하여 주요 우울장애와의 면역 유전학적 관련성을 알아보고자 하였다. 방 법 : DSM-Ⅳ진단 기준에 따라 주요 우울장애로 진단된 환자 77명을 선정하였으며 가톨릭대학교 의과대학 조혈모세포은행에서 보유하고 있는 149명의 정상 한국인 자료를 대조군으로 사용하였다. 전혈에서 DNA를 추출하였으며 중합효소반응으로 CTLA-4유전자 exon 1 부위를 증폭한 후 SSCP방법으로 유전?? 형별 분석하였다. 결 과 : 대조군과 주요 우울장애 환자군 사이의 CTLA-4 유전자형과 대립유전자의 발현 빈도를 비교시 유의한 차이가 없었다. 결 론 : 본 연구 결과 exon 1 CTLA-4 유전자형 및 대립유전자의 발현빈도는 주요 우울장애 환자군과 정상 대조군 사이에 차이가 없어, exon 1 영역은 후보 유전자로서의 가능성이 없었다. 향후 연구에서는 다양한 변인들에 따라 대상군을 임상적으로 동질성을 지닌 집단으로 세분하여 조사대상 유전자와의 관련성에 대한 연구가 이루어져야 하겠다. Objectives : This study was carried out to explore the relationship between major depressive disorder and CTLA-4 which is related to the immunologic function such as T cell regulation. Methods : Among the korean patients diagnosed as major depressive disorder according to DSM-Ⅳ, 77 patients without neurological illness, hormonal disorder, or comorbid mental illness were selected. The stored data of 149 normal Koreans from the Catholic Hemopoietic Stem Cell Bank of Korea, were used as a normal control group. The data of Korean control group were compared with those of the studies of different ethnics. DNA was extracted from whole blood and the exon I region of CTLA-4 gene was amplified by polymerase chain reaction. Gene typing was performed by using SSCP and then, the results were assessed. Results : There were no significant differences in genotype frquencies of CTLA-4*G/G, CTLA-4*G/A, and CTLA-4*A/A between the patients with major depressive disorder and the control group in Korean population(48.1% vs 46.3%, 41.6% vs 39.6%, 10.3% vs 14.1%, respectively).There were no significant differences in allelic frequencies of CTLA-4*G and CTLA-4*A between the patients with major depressive disorder and the control group in Korean population(68.8% vs 66.1%, 31.2% vs 33.9%, respectively). Conclusion : Considering negative result for the association of the exon I polymorphism of CTLA-4 gene with major depressive disorder in this study, the exon I polymorphism does not appear to be possible candidate gene for major depressive disorder. Moreover, further systematic researches including diverse clinical variables would required.

Chlamydia trachomatis에서 분리된 Cryptic plasmid DNA의 클로닝

유정한,김덕언,박일규,강정옥,최태열 대한임상병리학회 1996 대한임상병리학회지 Vol.16 No.5

취학전 아동들의 체격 및 기초체력에 관한 비교 연구

김태운,안병철,고기준,한재웅,이재규 釜山大學校 附設 體育科學硏究所 1997 體育科學硏究所 論文集 Vol.13 No.-

The purpose of the present investigation was to compare and analyze the physique and physical fitness for children(boys:876, girls:784, age: 7 yrs), and to correlation between physique and physical fitness 5 items. The measurement items of physique and physical fitness were height, weight and sitting trunk flexion, 50M run, standing long jump, foot balance, flexed arm hang test. The statistical analysis were calculated to mean and standard deviation for all measurement values and correlation coefficients between physique and physical fitness 5 items for children using SPSS/PC+ statistical package(α=.05). The conclusion of the present investigation was as follows; 1. Physique 1) In height, boys(118.31 ±23.92cm) has been significantly higher than girls(116.11 ±4.72cm)(P<0.05). 2) In weight, boys(22.31 ±3.54kg) has been significantly higher than girls(21.17 ±3.31kg)(P<0.01). 2. Physical fitness 1) In sitting trunk flexion, girls(11.67 ±4.37cm) has been significantly higher than boys(9.97 ±4.48cm)(P<0.01). 2) In 50M run, boys(12.58 ±1.30sec) has been significantly faster than girls(13.30 ±1.59sec)(P<0.01). 3) In standing long jump, boys(112.99 ±16.36cm) has been significantly higher than girls(98.94 ±16.24cm)(P<0.01). 4) In foot balance, girls(30.90 ±19.66sec) has been significantly higher than boys(26.65 ±19.25sec)(P<0.01). 5) In flexed arm hang, boys(8.68 ±7.94sec) and girls(8.58 ±8.11sec) had no significant difference. 3. Correlation between physique and physique and physical fitness 1) In correlation between height and physical fitness, boys were no little correlation in 5 items all, and girls and total were significantly low correlation(P<0.01) between height and 50M run, standing long jump. 2) In correlation between weight and physical fitness, boys and girls all were significantly low correlation between weight and standing long jump(P<0.05), flexed arm hang(P<0.01), and total were significantly low correlation between weight and 50M run(P<0.05), standing long jump(P<0.01), flexed arm hang(P<0.01).

여중생들의 신체조성과 심폐기능 및 심박수 회복율에 관한 비교 연구 : 비만 여중생과 정상 여중생을 중심으로

김태운,신군수,김종인,이광무,김성헌,안병철,고기준,한재웅,이재규 釜山大學校 附設 體育科學硏究所 1996 體育科學硏究所 論文集 Vol.12 No.-

The purpose of this study was to compare and analyze the relation between body composition, cardiorespiratory functions and percent heart rate recovery in obese and normal middle school female students. We used total of 12 middle school female students(3rd grade) as subject and devided them into two groups : The measurement items of cardiorespiratory functions were HR, VE, RQ, VO₂, VCO₂, VO₂/kg, O₂pulse, VE/VO₂, VE/VCO₂, before and after treadmill exercise load. The statistical analysis were M±SD and t-test for groups(α=.05) using ?? statistical package. The conclusion of this study was as follows ; 1. In 5 items(FM, LBM, %Fat, TBW, BMI) all of body composition, obese group has been significantly higher than normal group(P<0.01). 2. In heart rate and VO₂ of resting(before exercise loads) cardiorespiratory functions, normal group has been significantly higher than obese group(P<0.05). 3. In VEmax of cardiorespiratory functions after exercise loads, obese group has been significantly higher than normal group(P<0.05), and in VO₂max, obese group has been significantly higher than normal group(P<0.01). 4. In 1, 3, 5 minute percent recovery all of percent heart rate recovery after exercise loads, normal group has been higher than obese group but there was no statistical significant difference.

大學 男女 球技選手들의 最大無機的 Power

김태운,유재충,안덕균,선우섭,이한,손두욱,박충서 慶熙大學校 社會體育硏究所 1994 體育科學論叢 Vol.- No.7

The purpose of the present research is to compare characteristics of maximal anaerobic power observed in different types of sports and player's sex differences. We have reached the following conclusions from the results we obtained by measuring maximal anaerobic power and blood lactate concentration of 60 elite university male and female players during the exercise of bicycle ergometer: 1. As to absolute and relative values of maximal anaerobic power, male players are higher in the order of rugby and handball, whereas female players are higher in the order of hockey and soccer, but no significant differences are observed between types of sports. 2. Male players are noticably higher in absolute values of maximal anaerobic power(p<0.001), but relative value is very simi1ar to that of female players. 3. It is estimated that the fact, that female players show obvious higher mean anaerobic power(p<0.001) during the 3,4KP excercise is due to sex differences in ocdurrence work load of maximal anaerobic power. 4. Comparison of blood lactate concentration at each work load in different types of sports and player's sex differences show an increase in proportion to mean anaerobic power. The results given above clearly show the differences between the type of sports such as rugby and hockey requiring power and speed, and the type of sports such as handball and soccer requiring edurance.