족저압력분포 측정장비를 이용한 골프 스윙시 족저압 분석

이동기,이중숙,이범진,이훈식,김용재,박승범,주종필 한국운동역학회 2005 한국운동역학회지 Vol.15 No.1

D. K. LEE, J. S. LEE, B. J. LEE, H. S. LEE, Y. J. KIM, S. B. PARK, J. P. JOO. PIantar foot pressure analysis during golf swing motion using plantar foot pressure measurement system. Korean Journal of Sport Biomechanics, Vol. 15, No. 1, pp. 75-89, 2005. In this study, weight carrying pattern analysis and comparison method of four foot region were suggested. We used three types of club(driver, iron7, pitching wedge). This analysis method can compare between top class golfer and beginner. And the comparison data can be used to correct the swing pose of trainee. If motion analysis system, which can measure the swing speed and instantaneous acceleration at the point of hitting a ball, is combined with this plantar foot force analysis method, new design development of golf shoes to increase comfort and ball flight distance will be available. 1. Address acting, forces concentrated in rare foot regions and lateral foot of right foot. Back swing top acting, relatively high force occurred in medial forefoot region of left foot and forefoot region of right foot. Impact acting, high force value observed in the lateral rarefoot region of left foot and medial forefoot region of right foot. Finish acting, force concentration observed on the lateral region and rarefoot region of left foot. 2. Forces were increased in address of right foot with clubs length increased. All clubs, back swing top acting, high force value observed in the lateral forefoot region of right foot. All clubs, in impact, high force value observed in the lateral rarefoot region of left foot and medial forefoot region of right foot. Finish acting, force concentration observed on the rarefoot region in driver and lateral foot region in iron on left foot. 3. Right foot forces distribution were increased in address, back swing top and left foot force distribution were increased in impact, finnish

pHOxsFV벡터와 배아주간세포를 이용한 형질전환생쥐 생산 기초연구

이훈택,이봄이,정길생,김진회 건국대학교 동물자원연구센터 1998 動物資源硏究誌 Vol.19 No.-

pHook™-1 hapten 4-ethoxy-methylene-2-phenyl-2-oxazolin-5one(phOX)의 단일 항체 sFV를 암호화 하고 있으며, murine의 Ig k-chain V-J2-C 영역유래의 signal peptide에 의하여 항체를 세포 표면에 배열시키도록 고안되어 있다. 또한, 항체를 세포막 바깥쪽에 부착되어 있도록 하기 위해 PDGFR 유래의 transembrane domain의 C 말단에 결합되어 있다. 이렇게 고안된 vector을 발현하는 세포는 세포막에 sFV을 발현함으로, phOX로 코팅된 자석베드를 이용하여 배양체로부터 목적의 유전자를 발현하는 세포만을 분리할 수 있을 것이다. 따라서, 본 연구는 pHook™-1 유전자를 co-transfection함으로써 목적의 유전자를 가진 배아주간세포를 단시간 내에 효율적으로 선발하기 위하여 실시하였다. 또한, 배아주간세포에서 목적의 DNA 발현 또는 존재를 검증하기 위해 DNA 발현 또는 존재를 검증하기 위해 PCR 방법과 조직화학적 방법을 사용하였다. 형질전환유전자 발현을 transfection(유전자 전이) 후 4∼14일 사이에 모든 배아주간세포에서 확인되었다. Magnetic bead를 이용하여 선발된 세포에서 co-transfected DNA는 배아주간세포에서 효율절으로 삽입되었으며, 선발된 세포의 약 90%는 co-transfected 유전자를 발현하였다. 이 결과는 세포생리학에서 특이 유전자의 급성변이와 만성변이를 연구하거나, 또는 형질전환동물을 생산하기 위해 pHook™-1 목적유전자와 함께 전이함으로서 효율적으로 목적의 유전자를 가진 세포를 선발 가능함으로써 보다 간편하게 형질전환도 동물의 생산에 이용 가능하다는 사실을 확인하였다. pHook™-1 encodes a single-chain antibody(sFv) directed toward the hapten 4-ethoxy-methylene-2-phenyl-2-oxazolin-5-one(phOx): the signal peptide from the murine Igk-chain V-J2-C region is fused in front of coding region of the sFv to direct the antibody to the plasma membrane. The antibody is fused at the C-termius to the transmembrane domain from the platelet derived growth factor receptor(PDGFR), allowing the antibody to be anchored and displayed on the extracellular side of theemmbrane. Transfected cells expression sFv can be isolated from whole cultures by using magnetic coated with phOx and a strong magnetic strand. Thus, the present study was designed to apply the embryonic stem cells by using pHook™-1 . Cell-transduction efficiency was measured by morphometric analysis. Polymerase chain reaction and histochemistry were used to detect the presence and/or expression of objective DNA in embryonic stem cells. Transgene expression was detected in all cases between 4 and 14 day after transfection. In selected cells using magnetic bead, co-transfected DNA was also incorporated efficiently in embryonic stem cells and approximately 90% of the selected cells expressed co-transfected gene. This result suggested that this selection system can be used as a feasible tool, when pHook™-1 is cotransfected with objective gene, to isolate and study for acute and chronic changes of a specific gene in cellular physiology.

STEP 표준을 이용한 열교환기 형상 데이터 모델링

오해진,이범석 경희대학교 산학협력기술연구원 1996 산학협력기술연구논문집 Vol.2 No.-

Sharing and exchanging of product data are critical to the successful business in the industries. Engineers in the process industries use numerous software packages, some commercial and some private. Process and equipment designs are passed from operating companies to engineering and construction companies on paper. In turn, E&C companies will pass paper specifications to fabrications and contractors. The data must be produced to be accurate, up-to date, etc. A plant database must be kept even if the plant is discommissioned. These needs to be a single copy of each data thorough the life-cycle of the plant. The ISO-STEP developments for the actual implementation of data exchange programs and interfaces are briefly mentioned in this work. Especially, the shape of heat exchangers which are most widely used in the chemical plant is considered to be modeled based on ISO-STEP standard.

합천군 치면열구전색사업의 영구치 우식증 예방효과

김선창,이선미,김지영,김진범 대한구강보건학회 2003 大韓口腔保健學會誌 Vol.27 No.3

A clinic-and school-based fissure sealant program was initiated by the community health center in Habchon, Korea in 1996. Fissure sealants were applied limitedly to first molars of all 6-year olds, grade one of elementary schools in 1996. The program was expanded to more children annually by one grade. Children for sealants included all 6-10-year olds in grades one through five in 2000. The application of sealants was expanded to premolars besides molars. Children who lives close to health center or health sub-center visit the dental clinic of health center or sub-center by themselves for sealants. However, dentists and oral hygienists of health center or sub-center visits remote elementary schools and provide sealants at schools. To evaluate the effectiveness of a clinic-and school-based fissure sealant program in Habchon-gun, dental examinations were conducted on 6-14-year old 1,957 children of elementary and middle schools in Habchon-gun and control group, 1,277 children in 2000. The surveyed data were analyzed with SPSS statistical package. The obtained results were as follows; 1. DMF rates were 7.5% at &year olds and 53.5% at 6-and 10-year olds benefited by the sealant program of Habchon-gun Health Center, DMF rates in sealant group was lower than control group. 2. DMFT scores were 0.11 at 6-year olds, 1.33 at 10-year olds benefited by the sealant program of Habchon-gun Health Center. DMFT scores in sealant group was lower than control group. 3. The caries reduction rate from the sealant program was calculated as 56.0%, 31.4%, 43.1%, 28.9%, 30.4% at 6-,7-, 8-, 9- and 10-year olds respectively by the difference of DMFT scores between sealant group and control group. 4. Percentage of children with sealants was 52.8% and 95.5% at 6-and 10-year olds respectively. Mean number of teeth with sealants was 0.83 and 5.06 at 6-and 10-year olds respectively. 5. The fissure sealant program of Habchon-gun Health Center from 1336 to 2000 was evaluated to be effective to reduce dental caries on permanent teeth. These results substantiate that a significant reduction in dental caries can be achieved by the fissure sealant program.

0.2% 불화나트륨 용액으로 5년간 양치한 초등학교 아동의 영구치 우식증 예방효과

손석환,이재화,김지영,김진범 대한구강보건학회 2003 大韓口腔保健學會誌 Vol.27 No.2

Supervised weekly fluoride mouthrinsing(FMR) program with 0.2 percent neutral sodium fluroide solution has been implemented at primary schools in Pusan, Korea since 1995 to prevent the prevalent dental caries. Children of sixth grade in 2000 who had joined the weekly FMR program at four primary school in Pusan with a 0.2 percent sodium fluoride solution for five years from first grade in 1995 to fifth grade in 1999 were selected as experimental group. Children of sixth grade in 2000 who had not joined the FMR program until sixth grade and had not drunk fluoridated pulic water at two primary schools in the Bukgu(Norhtern) District of Ulsan were selected as control group. Samples were 295 in FMR group and 312 in control group. To estimate caries preventive effect, epidemiologic dental survey was performed at the schools of FMR and control group in 2000 for 11-year-old children. The surveyed data were analyzed with SPSS statistical package. The obtained results were as follws. 1. Children who experienced caries on permanent teeth were 71.2% in FMR group and 83.3% in control group. 12.1% of DMF rate decreased in FMR group compared to control group. 2. The DMFT scores were 2.68 in FMR group and 3.29 in control group. The difference of DMFT scores was 0.61 between fluoride mouthrinsing group. The caries reduction rate from 5-year FMR program was calculated as 18.5% by the difference of DMFT scores between FMR group and control group. 3. The DMFS scores were 4.04 in FMR group and 5.05 in control group. The difference of DMFS scores was 1.01 between FMR group and control group. The caries reduction rate from 5-year FMR program was calculated as 20.0% by the difference of DMFS scores between FMR group and control group. 4. Significant Caries Index of permanent teeth was 5.46 in FMR group and 6.02 in control group. 5. We suggest that fluoride mouthrinsing program should be developed to all primary schools to prevent dental caries.

동해안 석호의 육수학적 조사(1): 청초호

허우명,이상균,권상용,김동진,김범철 江原大學校 附設 環境硏究所 2001 環境硏究 Vol.18 No.-

Water quality and pollution state of Lake Chungcho were evaluated during three years from 1998 to 2000. We surveyed physicochemical parameters, and TSI(trophic state index) was calculated using TP, Chl. a, and SD(secchi disc transparency) data of growing season average. Water samples were collected bimonthly except freezing season. During the study period, total annual precipitation in 1998, 1999 and 2000 year was 1,797, 1,722 and 1,345 mm, respectively. Salinity and conductivity were high (29.3±5.5 ppt, and 45,105±7,585 μS/cm) then other lagoons in the Eastern Coast of Korea. Chemocline was formed by salinity at 0.5~1.5m water depth. As a result of this, DO concentration of hypolimnion was below 3.0 mgO₂/L. Especially, when intense chemocline was formed, temperature of hypolimnion was higher than epilimnion. Secchi disc transparency, chlorophyll a, and COD were 0.8±0.3m, 15.7±20.7 mg/㎥, and 3.1±0.8 mgO₂/L, respecively. Most of TN/TP ratios below 20, but concentration of TN and TP was high. Values of TSI ranged between 59 and 77, indicating a eutrophic condition in this system.

울산광역시민의 불소배합세치제 사용률

김지영,이재화,박혜경,김은경,김진범 대한구강보건학회 2003 大韓口腔保健學會誌 Vol.27 No.1

Fluoride-containing toothpaste is one of useful tools to apply fluoride for prevention of dental caries. The purpose of this study was to survey the user rate of fluoride-containing toothpaste at home for the oral health education of the use of fluoride-containing toothpaste. Questionnaires about the use of fluoride-containing toothpaste were distributed to the children of primary middle schools and adults in Buk-gu(Northern District) of Ulsan Metropolitan City, Korea. Collected questionnaires from 374 primary school children, 505 middle school children and 161 adults were analyzed. All collected date were analyzed using the SPSS program. The obtained results were as follows; 1. 36 brands of toothpaste were being used at home. 29 brands contained fluoride and 9 brands were the toothpaste for children. 2. Among total respondents, 97.4% used the fluoride-containing toothpaste. 3. The user rate of fluoride-containing toothpaste were 97.9% among elementary school children, 97.2% among middle school children and 96.9% among adults. There was no significant difference among groups. 4. Among respondents using fluoride-containing toothpaste, SMFP-containing toothpaste were used by 90.9% of subjects, NaF;9.9%, combination of SMFP and NaF;0.1%. 5. Only 33.0% of respondents correctly knew whether they really used the fluoride-containing toothpaste or not.

ANATOMICAL EXPANDER와 IMPLANT를 이용한 유방 재건의 경험

고법민,박원진,김재중,하범준,이재승,신명수 大韓成形外科學會 1999 Archives of Plastic Surgery Vol.26 No.3

The use of a tissue expander and implant is the simplest option for breast reconstruction after mastectomy. Use of a round dome-shaped prosthesis and the commonly used one-stage technique with a Becker type prosthesis, however, often produces an undesirable upper pole fullness. To overcome this and to achieve improved aesthetic results, we started using an anatomically-shaped expander and implant, as described by Maxwell, as a two-stage breast reconstruction. We reviewed the results of our 21 reconstructed breasts in 22 patients who were deemed suitable for reconstruction using this technique since January 1995. The most commonly used expander was 350cc (range 350-550cc) and an average of 4.2 inflations were required before replacing the expander with a permanent implant. All the expanders were placed in submuscular pockets and implant volume. The longest follow-up was 36 months. Few complications developed and most patients were satisfied with the results. We found that the anatomically-shaped expander and implant produced better aesthetic results compared to a done-shaped prosthesis.

Optical properties of InGaN/GaN multiple-quantum-well light-emitting diodes with superlattice and electron reservoir layer

Bom Lee,Il-Wook Cho,Kwanjae Lee,Jin Soo Kim,Mee-Yi Ryu 한국진공학회 2019 한국진공학회 학술발표회초록집 Vol.2019 No.8

Prenatally Diagnosed Uncommon Mosaic Autosomal Trisomy

Bom-Yi Lee,So-Yeon Park,Moon-Hee Lee,Jin-Woo Kim,Ju-Yeon Park,Eun-Young Choi,Yeon-Woo Lee,Ah-Rum Oh,Shin-Young Lee,Min-Hyung Kim,Hyun-Mee Ryu 대한의학유전학회 2009 대한의학유전학회지 Vol.6 No.1

Prenatal diagnosis of rare autosome mosaicism involvingchromosomes other than chromosome 13, 18, 21 or the sex chromosome is encountered prognostic dilemma during genetic counseling. We report four cases of level Ⅲ uncommon mosaicism of trisomy 5, 16 and 20,diagnosed prenatally. In case 1 with mosaic trisomy 20, there was a higher mosaic ratio of trisomy 20 in the repeat amniocentesis (62.1%) than in the first (36.6%) with normal fetal ultrasound finding except for a relatively small aorta on a 3-vessel view of the fetal heart. Case 2 showed a low rate of mosaic trisomy 20 (5.25%) in cultured amniocytes but normal karyotype in the repeat amniocentesis, who delivered a normal healthy baby. Case 3 showed a 13.6% of trisomy 16 mosaicism in the 30 cells of cultured amniocytes. Sixty cells from a fetal blood sample at termination showed non-mosaic 46,XX normal karyotype, while skin fibroblasts had 22.5% trisomy 16 in 40 metaphases. The autopsy showed ventricular septal defect (VSD). Case 4 with low grade mosaicism (10.5%) of trisomy 5 resulted in elective termination, though the ultrasoumd showed growsly normal fetus. Although level Ⅲ mosaicism is regarded as true mosaicism, it is difficult to predict the outcome of the fetus with rare mosaic autosome trisomy. Therefore mosaic autosome trisomy of fetus should be carefully interpreted with more various approaches including repeat sampling and targeted fetal ultrasound. 산전에서 성염색체와 13번, 18번, 21번 염색체를 제외한상 염색체의 모자이시즘은 발생빈도가 낮고 증례보고가 적어서 예후 예측이 어렵다. 저자들은 삼염색체성 5번, 16번, 20번의 산전진단 4례를 보고하고자 한다. 모자잌 삼염색체성 20번 2례 중 증례 1은 양수 염색체 검사에서 36.6%의 모자이시즘을 보였으나 재검한 양수 검사에서는 보다 높은 빈도 (62.1%)를 보였다. 증례 2에서는 양수 염색체 검사에서 모자이시즘 삼염색체성 20번이 5.25% 였으나, 재검 양수천자결과는 정상 핵형을 보였다. 증례 3은 30개의 양수세포에서 삼염색체성 16번의 모자이시즘이 13.6% 관찰되었다. 임신 종결 후, 총 60개의 태아 혈액 세포에서 모자이시즘 없는 정상 핵형이 관찰되었으나 태아의 피부 섬유아세포에서 얻은 40개의 중기상 세포에서는 22.5%의 삼염색체성 16번 모자이시즘을 보였다. 부검결과 심실중격결손(ventricular septal defect)이 관찰되었다. 증례 4는 76개의 중기상 세포에서 10.5%의 삼염색체성 5번 모자이시즘을 보였으나 태아의 초음파검사에서는 정상소견을 보였다. Level Ⅲ 모자이시즘은 진성 모자이시즘으로 간주되지만 발생빈도가 낮은 상염색체의 삼염색체성 모자이시즘은 태아의 예후를 예견하기 어려우므로 산전 진단시 여러 조직의 재검 및 태아 초음파 소견과 함께 다양한 임상적 접근 방법으로 그 해석에 신중을 기해야 할 것으로 사료된다.