정상배란성 월경주기에서 혈청 인슐린유사 성장인자 결합단백질의 양상

정재훈,김정구,Jeong, Jae-Hoon,Kim, Jung-Gu 대한생식의학회 1999 Clinical and Experimental Reproductive Medicine Vol.26 No.1

The insulin-like growth factor (IGF)s are believed to one of several growth factors that play an adjunctive role in ovarian follicular development. These factors circulate bound to a family of IGF-binding protein (IGFBP)s. It is known that circulating IGFBPs are involved in the transport of IGFs to tissues and modulate IGFs actions at local tissue. The purposes of this study were to evaluate changes in serum IGFBPs profiles during normal ovulatory menstrual cylce and to compare serum IGFBPs profiles in periovulatory phase of between normal ovulatory menstrual cylce and controlled hyperstimulated cycle. Fasting blood samples were obtained from 15 normal healthy women throughout normal ovulatory menstural cyle and on the day of aspiration of oocyte from 10 patients undergoing ovarian hyperstimuation for in vito fertilization-embryo transfer. Serum IGFBP-1 - IGFBP-4 were measured by western ligand blot and immunoprecipitation. Serum $17{\beta}$-estradiol was determined by radioimmunoassay. Type and molecular weight of serum IGFBP did not changed during normal ovulatory menstural cycle. No significant variation in the relative proportion and level of each IGFBP was found throughout normal ovulatory menstural cyle. Also, the relative proportion and level of each IGFBP did not correlated with serum $17{\beta}$-estradiol level. There was no significant difference in the relative proportion and level of each serum IGFBP between on the day of ovulation in normal ovulatory menstrual cylce and on the day of aspiration of oocyte in controlled hyperstimulated cycle. Our data indicate that IGFBPs have regulatory functions in ovary through an paracrine and autocrine rather than endocrine mechanism during normal ovulatory menstural cycle.

플라스틱 기판을 이용한 고분자 청색 유기발광다이오드의 발광 특성

정재훈,문대규,Jung, Jae-Hoon,Moon, Dae-Gyu 한국전기전자재료학회 2013 전기전자재료학회논문지 Vol.26 No.9

We have fabricated blue phosphorescent organic light-emitting devices (OLEDs) on a plastic substrate. The solution coated poly (9-vinylcarbazole) (PVK) host doped with Bis (3,5-difluoro-2-(2-pyridyl)phenyl_(2-carboxypyridyl)irdium(III) (FIrPic) guest molecules was used as an hole transporting emission layer. The device structure was ITO/PVK:FIrpic (50 nm, xwt%)/TAZ 50 nm)/LiF (0.5 nm)/Al (100 nm). The concentration of FIrpic molecule was varied from 1 wt% to 10 wt%. The OLED on plastic substrate exhibited maximum current efficiency of 18 cd/A with 5 wt% FIrpic molecules were doped into the PVK layer.

수종(數種)의 한약재의 Tyrosinase와 Elastase 활성 억제 효과에 대한 실험적 연구

정재훈,김경준,Jung, Jae-Hoon,Kim, Kyung-Jun 대한한방안이비인후피부과학회 2009 한방안이비인후피부과학회지 Vol.22 No.2

Objectives : The purpose of this study is to investigate whitening effects and anti-wrinkle effects of a few 80% ethanol extracted herbal medicines. Methods : In the first study, a few 80% ethanol extracted herbal medicines were screened for their inhibitory activities against the tyrosinase. In the second study, a few 80% ethanol extracted herbal medicines were screened for their inhibitory activities against elastase. Results : 1. We showed 28%, 27% and 19% inhibitions of mushroom tyrosinase at 500 $\mu$g/ml concentration of ASR, AIF and ABR extracts and they were showed higher anti-tyrosinase activity than arbutin's. We also could observe that the decreased mushroom tyrosinase activities in RR, CML, LR, AGR and TH extracts. 2. RR, AF and ABR (final concentrstion 1 mg/ml) were appeared 60%, 98%, 83% of inhibitions of elastase activity, and they were showed higher anti-elastase activity than that of ursolic acid. We also could observe that the decreased elastase activities in AIF, AR, LR and CML extracts. Conclusions : These results suggest that ASR, AIF and ABR extracts contribute to the anti-melanin activities and represent potential sources of whitening agent, and RR, AF and ABR extracts contribute to the anti-elastase activities and represent potential sources of anti-wrinkle agent. These results suggest that some herbal medicines could be strong potential sources of inhibition about anti-aging and whitening effects for the skin.

안와 상벽 골절과 광대뼈 골절의 임상 양상과 치료 및 동반된 안과적 진단

정재훈,이화,이종미,백세현,Jae Hoon Jung,Hwa Lee,Jongmi Lee,Sehyun Baek 대한안과학회 2012 대한안과학회지 Vol.53 No.4

Purpose: To investigate the clinical manifestations, management, and ophthalmologic complications of orbital roof fractures and zygoma fractures. Methods: A retrospective survey of 119 patients who visited Korea University Medical Center from June 2009 to June 2010 was performed. The sex, age, causes, fracture characteristics, neurologic injury, ocular injury, and combined facial bone fractures of patients who were diagnosed with orbital roof fracture and zygoma fracture were statistically analyzed. Results: The mean age of patients with orbital roof fracture was 33.0 years old. The most common cause of orbital roof fracture was traffic accident (36.1%) with 6 patients receiveing surgical treatement (9.8%). Among the ophthalmologic diagnoses of the patients with orbital roof fracture, traumatic iridocyclitis was the most common (7 eyes) followed by eyeball rupture (2 eyes). The mean age of patients with zygoma fracture was 36.6 years old. The most common cause of zygoma fracture was traffic accident (32.8%), with 51 patients receiving surgical treatement (87.9%). Among the ophthalmologic diagnoses of the patients with zygoma fracture, traumatic iridocyclitis was the most common (6 eyes), followed by commotio retina (4 eyes). Conclusions: The present study regarding clinical characteristics and treatment of orbital roof fracture and zygoma fracture is helpful for ophthalmologists regarding the treatment of accompanying ophthalmologic complications. J Korean Ophthalmol Soc 2012;53(4):577-581

상악전치부 심미에 대한 인식도 평가

정재훈,오상천,Jung Jae-Hoon,Oh Sang-Chun 대한치과보철학회 2003 대한치과보철학회지 Vol.41 No.5

Statement of problem : The beauty has a little different meaning according to a time, culture, and nation. Purpose : This study was undertaken to determine the Korean perception of the altered upper anterior dental esthetics including the lack of symmetry, the midline deviation, the gingival exposure, the inclination of incisal plane, the type of incisal plane, and the type of gingival line. Material and Method : 670 subjects were participated in this survey. A questionnaire accompanied by 12 sets of computer-manipulated images using 3D MAX 4.2 software was used to record the ranking of the geometric preference related to the anterior esthetic discrepancies in three or four degrees of alteration. The statistical significance of the differences between the groups was determined by a one-way ANOVA and a t-test. Results : The results obtained were as follows: 1) The Korean perception of the anterior dental esthetics according to the subjects' occupation, sex, and age was most affected by occupation. 2) The masked image emphasizing the dentition and lips appeared stranger than the non-masked image at the same alteration. 3) The lack of symmetry, which was expressed as a unilateral discoloration of the tooth, showed incongruity in any teeth of the anterior dentition. The incongruity was more severe as the degree occurred closer to the midline. 4) The deviation of midline was showed more severe strangeness as the degree of deviation increased. However, more than half of the subjects did not perceive a deviation of 5mm. 5) During smiling, the exposure of the upper gingiva showed more severe incongruity as the degree of gingival exposure increased. 77% of the subjects perceived strangeness at the gingival exposure of 4.5mm. 6) The inclination of the incisal plane appeared stranger as the degree of inclination increased. 62% of subjects perceived strangeness at the $7.5^{\circ}$ inclination of the incisal plane. 7) The type of incisal plane showed increasing strangeness in the order of convex/downward, straight/horizontal, and concave/upward. 80% of subjects perceived strangeness at concave/upward. 8) The type of gingival line was showed increasing incongruity in the order of the same, a little above, and a little under the zenith of the lateral incisor to the line joining the zenith of the central incisor and the canine. However, less than half the subjects did not perceive strangeness at any alteration of the gingival line. Conclusion : The Korean perception of the upper anterior dental esthetics was different to the westerner's perception in the some respects.

거대 분자운의 원적외선 특성

정재훈,김현구,김봉규,Jung, Jae-Hoon,Kim, Hyun-Goo,Kim, Bong-Gyu 한국천문학회 2006 天文學論叢 Vol.21 No.2

Infrared color-color diagram of 10 giant molecular clouds are examined to explore the dust property from the COBE Diffuse Infrared Background Experiment of the 100, 140, and $240{\mu}m$ emission. Four of them, Taurus, Mon OB1, Gem OB1, and Chameleon, show the anti-correlation in $R_{100/140}-R_{140/240}$ plot and the horizontal distribution in $R_{100/240}-R_{140/240}$ plot, which disagree with those of theoretical calculation. These could be explained by the depletion of $100{\mu}m$ and the excess of $140{\mu}m$ emission, though no existing dust model could support them. Mean color temperature of the anti-correlation region appears to be lower than that of the linear region, whose temperatures are 15.3, 17.0 K, respectively. And the linear region shows large dispersion in the plot of intensity relation. Both imply that a star formation would be more active, but not homogeneous, in the linear region compared to the anti-correlation region.

조절 가능한 온도감도를 지닌 광섬유격자 온도센서

정재훈,남희,이병호,Jung, Jae-Hoon,Nam, Hui,Lee, Byoung-Ho 대한전자공학회 1999 電子工學會論文誌, D Vol.d36 No.9

온도 팽창률이 다른 두 개의 금속을 광섬유 브래그 격자에 부착하여 그 온도감도를 조절할 수 있는 새로운 온도센서를 제안하였다. 이러한 방법으로 온도감도를 기존의 브래그격자에 비해 3.3까지 향상시켰으며 금속의 길이를 변화시켜 그 온도감도를 여러 가지로 조절할 수 있었다. By attaching two metals with different thermal expansion coefficients to a fiber Bragg grating, we show that the temperature sensitivity is successfully improved to 3.3 times that of bare fiber Bragg grating and controlled by changing the metal length.

급성 아토피 피부염 마우스 모델에서 한약조합약물의 염증반응 진정효과

정재훈,김경준,Jung, Jae-Hoon,Kim, Gyung-Jun 대한한방안이비인후피부과학회 2015 한방안이비인후피부과학회지 Vol.28 No.1

Object : The object of this study was effected of composed of 4 herbal medicines(Rubus coreanus, Rehmanniae Radix, Houttuynia cordata, Betulae cortex) on acute atopic dermatitis mice. Methods : BALB/c mice were divided 4 groups ; normal group, negative control group of acute atopic dermatitis mice induced by DNCB, treated apply to the back skin with the herbal medicine group, and treated orally with herbal medicine group. Treated with herbal medicine and DNCB during 2 weeks. After treated, measured WBCs, RBCs, and platelet in the blood, and analysed mRNA expression of spleen. Result : Composed herbal medicines could reduce WBCs, lymphocytes, monocytes, neutrophils, and eosinophils in the mouse blood. And, could down TNF-${\alpha}$ levels in spleen. In the skin tissue histology results, herbal medicines reduce the cells and T cells. Conclusion : Composed herbal medicines help to another inflammatory disease because they reduce the cells and T cells in the skin tissues. And they have inhibitory effects of TNF-${\alpha}$ mRNA expression, and Th 2 immune responses. Therefore herbal medicines use for an acute atopic dermatitis treatment.

Simultaneous Measurement of Strain and Temperature by use of Fiber Bragg Grating Written in an Erbium: Ytterbium-Doped Fiber

정재훈,Jung, Jae-Hoon Institute of Korean Electrical and Electronics Eng 2004 전기전자학회논문지 Vol.8 No.1

단일 광섬유 격자와 Yb와 Er이 첨가된 광섬유를 이용한 스트레인 및 온도의 동시 측정을 시행하였다. 스트레인과 온도에 대해서 $1100\;{\mu}{\varepsilon}$ and $50-180\;^{\circ}C$ 범위에서 $55.8\;{\mu}{\varepsilon}$ 와 $3\;^{\circ}C$의 오차를 가지고 측정하였다. 본 센서의 소형 및 저가의 특성으로 미루어 볼 때 넓은 범위의 스트레인 센서로 활용가치가 높다고 사료된다. We demonstrate a fiber-optic sensor scheme, capable of the simultaneous measurement of strain and temperature using a single fiber Bragg grating written in an erbium: ytterbium-doped fiber. This novel and compact fiber grating based sensor scheme can be used for synchronous measurement of strain and temperature over ranges of $1100\;{\mu}{\varepsilon}$ and $50-180\;^{\circ}C$ with rms errors of $55.8\;{\mu}{\varepsilon}$ and $3^{\circ}C$, respectively. The simple and low-cost sensor approach has a considerable potential, particularly for wide-range strain sensing applications in which high resolution is not required.

준공 BIM 구축을 위한 Graph-based SLAM 기반의 실내공간 3차원 지도화 연구

정재훈,윤상현,허준,Jung, Jaehoon,Yoon, Sanghyun,Cyrill, Stachniss,Heo, Joon 한국건설관리학회 2016 한국건설관리학회 논문집 Vol.17 No.3

현재 국내 대부분의 토목 건축 구조물이 BIM 정보가 부재한 상황에서 준공 BIM(as-built BIM)의 수요가 점차 증가하고 있다. 준공 BIM 구축을 위한 공간자료 취득에는 고밀도의 포인트 클라우드를 생성할 수 있는 레이저 스캐너가 주로 활용되고 있다. 하지만 기존의 고정식 스캔 시스템은 이동이 번거롭고, 정밀한 위치 선정이 필요 하며, 스캔 자료 정합을 위해 별도의 표지를 설치하거나 공액점을 추출하는 과정이 필요하다. 본 연구에서는 수작업을 최소화하기 위해 기존의 고정식 스캔 시스템을 대체할 수 있는 이동식 스캔 시스템을 제안하고자 하며, 기반 기술로 graph-based SLAM을 적용하였다. 테스트 장비는 총 세 개의 2차원 스캐너를 탑재하고 있으며, 중앙의 한 개는 수평으로 설치되어 graph 구축을 통한 이동경로취득에 사용되었고, 좌우 두 개는 수직으로 설치되어 시스템 진행의 연직 방향으로 주변 구조물에 대한 3차원 스캔 정보 취득에 사용되었다. 개발된 graph-based SLAM은 이동경로 상에 누적된 위치오차를 해소하기 위한 loop closure 처리 방법으로 Adaboost 기계학습을 적용하였다. 이는 특히 본 연구에서 사용한 장비와 같이 기계학습을 위한 다수의 feature 정보를 제공할 수 있는 멀티 스캐너 시스템에 적합한 방식이며, 두 실내공간을 대상으로 한 테스트에서 단일 스캐너 대비 false positive rate를 각각 7.9% 및 13.6%까지 줄일 수 있었다. 최종적으로 연구대상지역의 2차원 및 3차원 지도 구축을 통해 개발된 graph-based SLAM의 효용성을 확인하였다. In Korea, the absence of BIM use in existing civil structures and buildings is driving a demand for as-built BIM. As-built BIMs are often created using laser scanners that provide dense 3D point cloud data. Conventional static laser scanning approaches often suffer from limitations in their operability due to the difficulties in moving the equipment, the selection of scanning location, and the requirement of placing targets or extracting tie points for registration of each scanned point cloud. This paper aims at reducing the manual effort using a kinematic 3D laser scanning system based on graph-based simultaneous localization and mapping (SLAM) for continuous indoor mapping. The robotic platform carries three 2D laser scanners: the front scanner is mounted horizontally to compute the robot's trajectory and to build the SLAM graph; the other two scanners are mounted vertically to scan the profiles of surrounding environments. To reduce the accumulated error in the trajectory of the platform through loop closures, the graph-based SLAM system incorporates AdaBoost loop closure approach, which is particularly suitable for the developed multi-scanner system providing more features than the single-scanner system for training. We implemented the proposed method and evaluated it in two indoor test sites. Our experimental results show that the false positive rate was reduced by 13.6% and 7.9% for the two dataset. Finally, the 2D and 3D mapping results of the two test sites confirmed the effectiveness of the proposed graph-based SLAM.