Helicobacter pylori 음성 위암

장진석 대한상부위장관ㆍ헬리코박터학회 2017 Korean Journal of Helicobacter Upper Gastrointesti Vol.17 No.3

Although Helicobacter pylori is considered the main etiological factor in gastric cancer, at least 5.4% of gastric cancer cases in South Korean patients are H. pylori-negative. However, false-negative H. pylori results should be considered. The definitions of H. pylori status in patients with atrophic gastritis but negative tests for H. pylori are variable. Inaccurate H. pylori detection systems can interfere with interpretation of the results. Even when H. pylori has been eradicated, gastric atrophy and intestinal metaplasia resulting from long-term colonization can occur. It is very difficult to determine whether patients with gastric cancer, who frequently have advanced gastric atrophy and intestinal metaplasia, have had previous H. pylori infection based on invasive tests. In addition, H. pylori-negative gastric cancers present with a more advanced pT classification and a more advanced stage than H. pylori-positive gastric cancers. Negative H. pylori status appears to be an indicator of poor prognosis in patients with gastric cancer, and is independent of other well-known clinical and pathologic prognostic variables.

암성 통증의 관리

장진석,Jin Seok Jang 대한소화기암연구학회 2014 Journal of digestive cancer reports Vol.2 No.2

Cancer pain is one of the most serious undesirable and unsolved complications for the cancer patients. Despite significant improvements in the management of cancer pain through past decades, it is still perceived as insufficient. Effective management of pain starts on a comprehensive assessment to identify the origin and characteristics of the pain. Then, appropriate multidisciplinary medical and surgical interventions could provide optimal treatments. With intensive attentions, complete or partial pain relief with tolerable side effects of the medication will be obtained and it will improve the quality of life of cancer patients.

조기위암과 위이형성증의 근치적 치료 : 내시경적 점막하박리술(ESD)의 치료성적

장진석,최석렬,한상영,노명환,이종훈,이성욱,이은주,권병표,최해종,고인영,이신애 대한외과학회 2005 대한외과학회 학술대회 초록집 Vol.2005 No.10

미국 농교육의 발전과정 분석

장진석 국립특수교육원 2007 특수교육연구 Vol.14 No.2

>Analyzing the Developing Process of the DeafEducation in the USAJinseok, Chang(Korea Nazarene University)The purpose of this study is to analyze the developmental process of the Deaf edu-cation in the USA. The results of the analyzation are as following;First, before the formal schooling, only very limited rich people could teach theirdeaf children at home by personally employed teacher, and send Europe to studywhile most people could have no way teach their children.Second, the first formal residental school for the Deaf was opened in Hartford in1817 owing to Cogswell, Gallaudet and Clerc s effort, and 30 schools could be operat-ed for 3,246 deaf students in the whole country until 1869 and most of them were sup-ported by the state government in finances, and they tried to make the deaf studentsbe able to speak oral language and prepare their jobs, and their school life is very tightin detailed system. Third, even if they had forbidden the deaf students using the sign language andday schools had been operated to forbid the deaf students using the sign language, ithas been alive, using owing to the continuing efforts to keep it by the Deaf, anddeveloping and using for the Deaf now since it was admitted as a formal language byStokoe s study in 1960s. Fourth, the status of deaf people could have been promoted in intellectual, social

Cutting Head Attachment Design for Improving the Performance by using Multibody Dynamic Analysis

장진석,유완석,강훈,조정우,정명식,이상곤,조용재,이재욱,Jamal Rostami 한국정밀공학회 2016 International Journal of Precision Engineering and Vol.17 No.3

Design technologies of a cutting head attachment for mechanical excavation works are studied for improving grinding efficiency. Similar to a hydraulic breaker, a cutting head attachment is attached to the front of an excavator. However, unlike the hydraulic breaker, which breaks rocks via repeated mechanical knockings, a cutting head attachment grinds rocks via the rotational motion of a conical drum. Hence, generally the grinding efficiency and working speed of a cutting head attachment is higher than those of a hydraulic breaker. Further, the working noise is significantly low because of the same reasons. In the cutting head attachment, the grinding tools, named as pick cutters, are arranged, and they perform the role of breaking rocks by interacting with them. Hence, it is very important to arrange these tools for improving the grinding efficiency. In this study, arrangement design methodologies of several pick cutters are developed by multi-body dynamics analysis. Further, the grinding efficiency of the designed pick cutter arrangement is studied for sumping and shearing cutting works through excavator’s boom motions.

한ㆍ미 수화어휘의 언어학적 공통특성 분석 : 주기도문을 중심으로

장진석 국립특수교육원 2008 특수교육연구 Vol.15 No.2

이 논문은 한·미 수화의 언어학적 공통특성을 밝히는데 목적이 있다. 분석결과는 다음과 같다. 첫째, 한국어를 한국수화로, 영어를 미국수화로 실현했을 때의 그 어휘 수가 같지 않았다. 둘째, 수화는 한국수화·미국수화 공히 수위(location) 수형(handshape), 수동(movement), 수향(orientation), 비수지신호(nonmanual signal)등의 언어적 체계를 갖춘 하나의 언어이다. 셋째, 수화는 공간 속에서 실현되는 공간성, 이를 귀로 듣는 것이 아니라 눈으로 보고 그 의미를 판단하는 시각성, 긴 문장어를 최소한으로 단축하여 표현하는 축약성 등의 특성이 있다. 넷째, 수화는 수많은 신호체계로 구성되어 있어 음성언어를 문자화했을 때 수많은 어휘의 체계적인 합성이 문장이 되듯이 수화 또한 수많은 신호들의 조화로운 합성이다. 다섯째, 한·미 수화에는 유사성과 어원이 있다. 여섯째, 한·미 수화는 그 구조와 체계가 서로 전혀 달라 한국수화를 미국수화로 또는 미국수화를 한국수화로 막바로 치환하여 의미를 전달할 수는 없다. The aim of this study is analyzing the linguistic common characteristics of Korean and American Sign Language. The results of analyzing is as followings; First, When Korean language is translated into the Korean Sign Language(KSL) and English language is translated into the American Sign Language(ASL), the numbers of the sign language words formed as symbols or gestures are not same between the Korean and American Sign Language. Second, Sign Language is one of the formal language which have the linguistic common systems such as location, handshape, movement, orientation and nonmanual signal. Third, Sign Language has the characteristics such as the sense of space being formed and realizing in the space, the sense of sight which makes the person be able to see and decide what he sees, and the sense of reducing the long sentence words as short as possible. Fourth, Sign Language is harmonious mixed language of lots of symbols like the sound language which has a lot of words connected systematically in the long sentence. And there are sign word formed as initial letter. Fifth, there classifier and original roots of sign words. Sixth, the Korean and American Sign Language can't directly translated into the another language each other because the linguistic structures and systems is quite different from each other.

Prostate-Specific Antigen Density as a Powerful Predictor of Extracapsular Extension and Positive Surgical Margin in Radical Prostatectomy Patients with Prostate-Specific Antigen Levels of Less than 10 ng/ml

장진석,최훈,장영섭,김진범,오미미,문두건,배재현,천준 대한비뇨의학회 2011 Investigative and Clinical Urology Vol.52 No.12

Purpose: To assess the ability of preoperative variables to predict extracapsular extension (ECE) and positive surgical margin (PSM) in radical prostatectomy patients with prostate-specific antigen (PSA) levels of less than 10 ng/ml. Materials and Methods: From January 2008 to December 2009, 121 patients with prostate cancer with PSA levels lower than 10 ng/ml who underwent radical prostatectomy were enrolled in the study. The differences in clinical factors (age, PSA, PSA density [PSAD], digital rectal examination [DRE] positivity, positive magnetic resonance imaging [MRI], Gleason sum, positive core number, and positive biopsy core percentage) with ECE and the presence of positive margins were determined and their independent predictive significances were analyzed. Results: The ECE-positive patients had higher PSA, PSAD, and MRI-positive percentages, and PSM patients had higher PSA, PSAD, MRI-positive percentages, Gleason sum, and positive biopsy core percentages for prostate cancer. In the multivariate analysis, PSAD and MRI positivity were the best independent predictors for ECE, and PSA and PSAD were the best independent predictors of PSM. By receiver operating characteristic curve analysis, PSAD had better discriminative area under the curve value than did PSA for ECE (0.765 vs 0.661) and PSM (0.780 vs 0.624). The best predictive PSAD value was 0.29 ng/ml/cc for ECE and 0.27 ng/ml/cc for PSM. Conclusions: PSAD has relevance to ECE (plus MRI findings) and PSM (plus PSA). PSAD might be a powerful predictor of ECE and PSM preoperatively in patients undergoing a radical prostatectomy with PSA levels of less than 10 ng/ml. Purpose: To assess the ability of preoperative variables to predict extracapsular extension (ECE) and positive surgical margin (PSM) in radical prostatectomy patients with prostate-specific antigen (PSA) levels of less than 10 ng/ml. Materials and Methods: From January 2008 to December 2009, 121 patients with prostate cancer with PSA levels lower than 10 ng/ml who underwent radical prostatectomy were enrolled in the study. The differences in clinical factors (age, PSA, PSA density [PSAD], digital rectal examination [DRE] positivity, positive magnetic resonance imaging [MRI], Gleason sum, positive core number, and positive biopsy core percentage) with ECE and the presence of positive margins were determined and their independent predictive significances were analyzed. Results: The ECE-positive patients had higher PSA, PSAD, and MRI-positive percentages, and PSM patients had higher PSA, PSAD, MRI-positive percentages, Gleason sum, and positive biopsy core percentages for prostate cancer. In the multivariate analysis, PSAD and MRI positivity were the best independent predictors for ECE, and PSA and PSAD were the best independent predictors of PSM. By receiver operating characteristic curve analysis, PSAD had better discriminative area under the curve value than did PSA for ECE (0.765 vs 0.661) and PSM (0.780 vs 0.624). The best predictive PSAD value was 0.29 ng/ml/cc for ECE and 0.27 ng/ml/cc for PSM. Conclusions: PSAD has relevance to ECE (plus MRI findings) and PSM (plus PSA). PSAD might be a powerful predictor of ECE and PSM preoperatively in patients undergoing a radical prostatectomy with PSA levels of less than 10 ng/ml.

[입선] 너와 나의 사이학교

장진석 한국교육시설학회 2016 교육시설디자인 공모전 Vol.2016 No.4

직장 유암종 2례

장진석,한상영,김동현 啓明大學校 醫科大學 2002 계명의대학술지 Vol.21 No.1

직장 유암종은 최근 항문 직장 부위의 검사 증가로 인하여 점차로 증가하는 추세를 보이고 있는데, 크기가 작고 원격전이가 없는 경우는 내시경적 국소 절제술로 치료를 하고 있다. 저자들은 직장에 발견된 작은 크기의 유암종을 내시경적 국소 절제술로 제거한 2례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Carcinoid tumors are enigmatic slow growing malignancies which occur most frequently (74%) in the gastrointestinal tract. Rectal carcinoids comprise 12.6% of all carcinoid tumors and represent the third largest group of the gut carcinoids. The initial symptoms of carcinoid may be nonspecific when present and symptoms are dependent on the location and extent of the tumor. The majority of patients with rectal carcinoid tumors are asymptomatic, and the tumor is after diagnosed incidentally at endoscopy, surgery, or autopsy. Rectal carcinoid tumors are generally small and rarely metastatic and it is known that about 15% of these tumors frequently metastasize to distant organs (especially, liver) when its size is larger than 2 ㎝. Endoscopic resection may be the best treatment for small tumors. Recently, we experienced two cases of rectal carcinoid tumors which were treated by endoscopic polypectomy, therefore, the cases are presented in this paper with a relevant literature review.

A Study on Improvements in Spray Performance of a Pneumatic Nebulizer

장진석,조정우,정명식,조용재,이상곤,이우종,이재욱,유완석 한국정밀공학회 2015 International Journal of Precision Engineering and Vol. No.

Nebulizers are inhalers for treating respiratory problems by converting aqueous solutions into aerosols of respirable size (1-5 μm) in the lower respiratory tract. In this study, improvements in the spray performance of the baffle type pneumatic nebulizer are investigated. First, to determine the causes of spray performance degradation, the reverse engineering of two pneumatic nebulizers is carried out. As a result, it was found that the major cause of performance degradation is the significant distortion of the inner parts due to the post-deformation after injection molding. Therefore, in this study, design changes are made to reduce post-deformation. Subsequently, to verify the spray performance of the suggested model, an injection molding analysis, flow analysis, and physical experiment are conducted. The results confirm that the suggested design helps improve the spray performance of a pneumatic nebulizer