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자연산 대하(Fenneropenaeus chinensis)에서 검출된 노랑머리 바이러스 Genotype 8의 계통분류학적 특성
장광일 ( Gwang Il Jang ),김보성 ( Bo Sung Kim ),오윤경 ( Yun Kyeong Oh ),황지연 ( Jee Youn Hwang ),권문경 ( Mun Gyeong Kwon ),김수미 ( Sumi Kim ) 한국수산과학회 2021 한국수산과학회지 Vol.54 No.5
Yellow head virus (YHV) is a rod-shaped positive-sense single-stranded RNA virus, classified into the genus Okavirus, family Roniviridae, and order Nidovirales. In this study, 200 fleshy prawns (Fenneropenaeus chinensis) collected from the vicinity of Narodo in Goheung-gun, Korea, were screened for the presence of yellow head complex viruses and related genotype such as YHV genotype 8. The detection rate of YHV genotype 8 among the 200 fleshy prawns, determined using nested RT-PCR (reverse transcription polymerase chain reation), was 39.0%. Phylogenetic analysis of the ORF1b gene of YHV showed that eight distinct genetic lineages were detected. The four strains of YHV genotype 8 obtained in this study formed a robust clade with the YHV genotype 8 group that was first isolated from fleshy prawns in China suspected to have acute hepatopancreatic necrosis disease (AHPND).
능동문서를 기반으로 하는 SLA 관리 시스템 UI 구현
이광일(Gwang-Il Lee),김상락(Sang-Rak Kim),배재학(Jae-Hak J. Bae),장길상(Gil-Sang Jang) 한국정보과학회 2011 한국정보과학회 학술발표논문집 Vol.38 No.1B
최근 SOA와 클라우드 컴퓨팅 기반의 IT 서비스가 증가함에 따라 정보처리 분야에서 SLA(Service Level Agreement)가 주목을 받고 있다. 통상의 SLA는 종이에 자연언어로 표현되는 것이어서 SLA 체결, SLA 관리나 SLA 기반 정보처리의 자동화가 제한된다. 오늘날과 같은 SOA, 온 디맨드 서비스, 유틸리티 컴퓨팅, 클라우드 컴퓨팅 환경에서는 서비스를 통합 자동관리할 수 있는 기술이 필요하다. 본 논문에서는 능동문서 기반의 ASLM(Active Service Level Managenment)의 계약체결 사용자 인터페이스(UI: User Interface)를 구현하여 일반 문서의 경우와 비교하여 보았다. 그 결과 ASLM의 UI가 SLA 체결, SLA 유지보수 자동화, 그리고 사용자의 편의성에서 SLA 기반의 계약업무 처리에 보다 효과적임을 알 수 있었다.
표적 가림 예측에 의한 기억추적 알고리즘 개발 및 구현
김소현,장광일,권강훈,정진현,Kim, So-Hyun,Jang, Gwang-Il,Kwon, Kang-Hoon,Jung, Jin-Hyun 한국군사과학기술학회 2009 한국군사과학기술학회지 Vol.12 No.3
In this paper, the Autocoast algorithm is proposed for EOTS to overcome the target occlusion status. Coast mode, one of tracking modes, is to maintain the servo slew rate with the tracking rate right before the loss of track. The Autocoast algorithm makes decision of entering coast mode by the prediction of target occlusion and tries to refind target after the coast time. This algorithm composes of 3 steps, the first step is the prediction process of the occlusion by target-like background, the second one is the check process of the occlusion happened after background intensity variation, and the last one is the process of refinding target. The result of computer simulation, test under laboratory, and real test with EOTS shows the applicability for the automatic video tracking system.
Renal Manifestations and Imaging Studies of Kawasaki Disease
오지영,박세진,김선정,장광천,김유리아,신재일,김기혁,Oh, Ji Young,Park, Se Jin,Kim, Sun Jung,Jang, Gwang-Cheon,Kim, Uria,Shin, Jae Il,Kim, Kee Hyuck Korean Society of Pediatric Nephrology 2013 Childhood kidney diseases Vol.17 No.2
목적: 본 연구는 가와사키 질환의 신장 침범에 대하여 비교적 덜 침습적이며, 특이도와 민감도가 높은 검사인 Technetium-99m dimercaptosuccinic acid scintigraphy (DMSA renal SPECT)을 통하여 밝혀보고자 한다. 방법: 2011년 3월부터 10월까지 국민건강보험 일산병원에서 가와사키로 진단된 15명의 환아들을 대상으로 진행하였다. 15명의 환아 모두 가와사키의 급성기에 DMSA renal SPECT를 시행하였다. 또한 신장 세뇨관 손상 지표인 요중 ${\beta}2$-microglobulin (${\beta}2$-MG)을 측정하여 이를 통한 가와사키 환아에서 신장 손상의 조기 진단 가능 여부를 연구해보았다. 결과: 환아 15명 모두의 신기능 검사는 정상이었다. 소변 검사상 현미경적 혈뇨와 농뇨가 각각 13%, 33%에서 관찰되었다. 요중 ${\beta}2$-MG는 46%에서 증가된 소견을 보였다. 또한 환아들을 요중 ${\beta}2$MG를 기준으로 증가되어 있는 군과 증가되지 않은 군으로 나누어 비교, 분석해 보았으며, 두군간에 임상 증상, 임상 검사, 초음파 검사 및 심초음파 검사에서 유의한 차이를 보이지 않았다. 모든 환아에서 DMSA renal SPECT는 정상 소견을 보였다. 결론: 본 연구에서 가와사키 질환의 신장 침범은 경한 소변 검사 이상 및 일부 환아에서의 요중 ${\beta}2$-MG의 상승 소견을 보였으며, DMSA renal SPECT에서 관찰될 정도의 신장 침범은 보이지 않았다. Purpose: The aim of this study was to verify renal inflammation following Kawasaki disease (KD) using single photon emission computed tomography along with Technetium-99m dimercaptosuccinic acid scintigraphy (DMSA renal SPECT). Methods: From March 2011 to October 2011, 15 patients diagnosed with KD at the National Health Insurance System Ilsan Hospital were enrolled in the study. All patients underwent DMSA renal SPECT to evaluate renal involvement during the acute phase of KD. Urine ${\beta}2$-microglobulin (${\beta}2$-MG), a marker of renal proximal tubular dysfunction, was also measured to assess renal damage. Results: All 15 patients had normal renal function test results. However, microscopic hematuria and pyuria were observed in 13% and 33% of the patients, respectively. Moreover, urine ${\beta}2$-MG was elevated in 46% of the patients. In addition, patients were divided into two groups based on ${\beta}2$-MG level: those with an increased ${\beta}2$-MG level, and those with a normal ${\beta}2$-MG level. No significant differences were found between these two groups in clinical characteristics, laboratory, sonography, and echocardiography findings. All patients' DMSA renal SPECT scans were normal. Conclusion: Our study showed that mild abnormalities in the urinalysis and elevated urine ${\beta}2$-MG were the only findings of renal involvement in KD. However, no aggressive renal manifestations were detected on DMSA renal SPECT.
김상락(Sang-Rak Kim),이광일(Gwang-Il Lee),배재학(Jae-Hak J. Bae),장길상(Gil-Sang Jang) 한국정보과학회 2011 한국정보과학회 학술발표논문집 Vol.38 No.1B
최근 기업들이 SOA, 웹 서비스, 유틸리티 컴퓨팅, 클라우드 컴퓨팅 등과 같은 서비스 지향적인 컴퓨팅 환경에 관심을 가지면서 SLA(Service Level Agreement) 기반의 자동화된 계약관리를 원하고 있다. 일반적으로 SLA는 종이에 자연언어로 표현되어 있어서 SLA 관리나 SLA 기반의 정보처리의 자동화가 제한된다. 이에 본 논문에서는 문서형 SLA를 실행가능한 언어로 표현하는 방법을 제안한다. 그 방법의 핵심은 SLA 문장을 단문, 중문, 또는 복문 형식으로 재구성하고 각 문장을 술어논리로 표현한 뒤, 이를 Prolog 기반 프로그램으로 변환하여 실행가능한 SLA(Active SLA)를 얻는다는 것이다. 이와 함께 ASLA를 활용한 SLA 기반의 계약관리 업무의 자동화에 대한 구체적인 예도 볼 것이다.
한국 성인의 벌독으로 인한 아나필락시스: 국내 다기관 후향적 연구
이수경 ( Su Kyoung Lee ),예영민 ( Young Min Ye ),박해심 ( Hae Sim Park ),장광천 ( Gwang Cheon Jang ),지영구 ( Young Koo Jee ),박혜경 ( Hye Kyung Park ),고영일 ( Young Il Koh ),김주희 ( Joo Hee Kim ),김철우 ( Cheol Woo Kim ),허규영 대한천식알레르기학회 2014 Allergy Asthma & Respiratory Disease Vol.2 No.5
Purpose: We investigated the causes, clinical features, and risk factors of bee venom anaphylaxis in Korea. Methods: The medical records of the diagnosis of anaphylaxis during a 5-year period from the 14 hospitals in Korea have been retrospectively reviewed. Cases of bee venom anaphylaxis were identified among anaphylaxis patients, and subgroup analyses were done. Results: A total of 291 patients were included. The common cause of bee species was vespid (24.6%) in bee venom anaphylaxis, followed by honeybee and vespid (8.8%), apitherapy (7.7%), and honeybee (2.0%), although the causative bee species were commonly unknown (56.9%). The severity of anaphylaxis was mostly mild-moderate (72.9%), and common clinical manifestations included cutaneous (80.6%), cardiovascular (39.2%), respiratory (38.1%), and gastrointestinal (13.1%) symptoms. Portable epinephrine auto-injectors were prescribed to 12.1% of the patients. Subject positive to both vespid and honeybee showed more severe symptoms and higher epinephrine use (P<0.05). The severity was significantly associated with older age, but not with gender, underlying allergic disease, or family history. Apitherapy-induced anaphylaxis showed a higher rate of hospitalization and epinephrine use than bee sting anaphylaxis (P<0.05). Conclusion: Vespid is the most common cause of bee venom anaphylaxis in Korea. It is suggested that positivity to honeybee and vespid may be associated with more severe symptoms.(Allergy Asthma Respir Dis 2014;2:344-351)
전혜진 ( Hye Jin Jeon ),이초롱 ( Chorong Lee ),김범근 ( Bum Keun Kim ),김수미 ( Sumi Kim ),장광일 ( Gwang Il Jang ),이강윤 ( Gahngyoon Rhee ),권혜민 ( Hyemin Kwon ),한지은 ( Jee Eun Han ) 한국수산과학회 2021 한국수산과학회지 Vol.54 No.5
Vibrio parahaemolyticus associated with acute hepatopancreatic necrosis disease (Vp<sub>AHPND</sub>) and Enterocytozoon hepatopenaei (EHP) are the two most important pathogens in shrimp aquaculture and they have caused enormous losses to the shrimp industry worldwide. In ponds, the major target organ for the two pathogens is the hepatopancreas, and infection with EHP is a known potential risk factor for Vp<sub>AHPND</sub> infection. This study aimed to develop a PCR (polymerase chain reaction)-based diagnostic method for simultaneously detecting Vp<sub>AHPND</sub> and EHP. The newly developed PCR diagnostic method could be used to test various samples, such as seawater, shrimp, and feces. The diagnostic method exhibited high sensitivity and specificity for both pathogens. This will help reduce the potential economic losses that may have been caused by the two major shrimp pathogens, Vp<sub>AHPND</sub> and EHP, and will allow for the efforts and time spent combatting them to be dedicated elsewhere.
이연경 ( Yeon Kyung Lee ),김미경 ( Mi Kyeong Kim ),강혜련 ( Hye Ryun Kang ),김태범 ( Tae Bum Kim ),손성욱 ( Seong Wook Sohn ),박혜경 ( Hye Kyung Park ),고영일 ( Young Il Koh ),장광천 ( Gwang Cheon Jang ),김철우 ( Cheol Woo Kim 대한천식알레르기학회 2015 Allergy Asthma & Respiratory Disease Vol.3 No.3
Purpose: To investigate whether causes of anaphylaxis vary according to regions and seasons in Korean adults. Methods: Based on previous retrospective studies of anaphylaxis between 2007 and 2011 at the 15 university hospitals. Regions were classified into 4 groups: region I, Seoul; region II, Gyeonggi; region III, Chungcheong; and region IV, Chonnam and Busan. The cases induced by 5 major allergens including drugs, food, bee sting, radiocontrast media, and exercise, were analyzed in the present study. Results: Among a total of 1,661 cases reported (53% male, 45.9±16.0 years), 367 (22.2%), 706 (42.5%), 319 (19.2%), and 269 cases (16.2%) were enrolled in regions I, II, III, and IV, respectively. Of the 5 major allergens, drugs (37.3%) were the most frequently reported, followed by food (25.7%), bee sting (17.9%), radiocontrast media (12.9%), and exercise (6.2%). There was no significant difference in the total occurrence of anaphylaxis in 4 seasons (374 in spring, 460 in summer, 460 in autumn, and 367 in winter). Multiple logistic regression analysis revealed that drug-induced anaphylaxis was significantly associated with the winter season (odds ratio [OR] 1.0 vs. OR 0.597, P<0.05 for spring; OR 1.0 vs. OR 0.481, P<0.01 for summer; OR 1.0 vs. OR 0.653, P<0.05 for autumn). Food-associated anaphylaxis was mainly reported in region I, whereas the frequency of insect sting was relatively higher in regions II, III, and IV than in region I. Older age and female gender were significantly associated with drug-induced anaphylaxis. Conclusion: Specific causative allergens of anaphylaxis in adults may vary according to age, gender, region, and season in Korea.(Allergy Asthma Respir Dis 2015;3:187-193)