전자광학추적장비와 레이더 사이의 표적탐지영역의 차이보상방법 개선

유형곤,권강훈,김영길,Yoo, Hyeong-Gon,Kwon, Kang-Hoon,Kim, Young-Kil 한국정보통신학회 2013 한국정보통신학회논문지 Vol.17 No.12

일반적으로 함정은 표적을 탐지하고 추적하는 기능을 하는 다양한 장비를 보유하고 있으며 각 장비들 간의 정보교류를 통해 보다 정확하고 신속하게 대상 표적을 추적하고 있다. 이런 장비들은 대체로 유사한 표적탐색영역(FOV)을 보유하지만 일부는 해당 장비의 오차범위(Resolution) 한계로 인해 장비간의 차이가 발생하기도 한다. 본 논문에서는 전자광학추적장비(Electro Optic Tracking System)와 레이더 시스템 간의 표적탐색영역(FOV) 차이를 보상하기 위해 사용된 전자광학추적장비 표적탐색 방식을 랜덤한 표적정보를 기준으로 다양한 방법을 통해 탐색시간을 단축하고, 자동으로 표적을 탐지/추적할 수 있는 방법에 대해 연구하였다. This is an example we generally have a variety of equipment that can detect and track the targets and track them quickly and accurately through the information exchange among each piece of equipment. These equipment have similar detection areas (FOV), but some are different due to the limit of the resolution of the equipment. In this paper, we studied the method of reducing detection time and tracking the targets automatically.

Efficacy of Stiripentol in Dravet Syndrome with or without SCN1A Mutations

조민정,권순성,고아라,이승태,이영목,김흥동,정희정,김세희,이준수,김대성,강훈철 대한신경과학회 2018 Journal of Clinical Neurology Vol.14 No.1

Background and Purpose The aim of this study was to determine the effectiveness of stiripentol (STP) add-on therapy to valproate and clobazam in patients with Dravet syndrome (DS) according to the presence of mutations in the sodium channel alpha-1 subunit gene (SCN1A). Methods We performed direct sequencing to analyze SCN1A mutations in 32 patients with clinically confirmed with DS, and classified them into mutation (pathogenic or likely pathogenic) and nonmutation groups based on American College of Medical Genetics and Genomics guidelines. We compared the efficacy of STP in reducing the seizure frequency between the two groups. Results The 32 patients comprised 15 patients in the mutation group (with definite SCN1A mutations) and 17 patients in the nonmutation group with variants of unknown significance or benign variants. The clinical profile did not differ significantly between the mutation and nonmutation groups. The seizure frequency relative to baseline reduced by 72.53±23.00% (mean±SD) in the mutation group versus 50.58±40.14% in the nonmutation group (p= 0.004). The efficacy of STP was better in DS patients with missense mutations that in those with truncation mutations, and was not favorable in patients with mutations at linkers between domains (DII–DIII), linkers between segments of domain I (DI S1–S2), or splice sites, although the small number of patients prevented statistical analyses. Conclusions The efficacy of STP was significantly better in DS patients with definite SCN1A mutations than in those without mutations.

Topiramate로 치료 받는 환아의 나이와 용량에 따른 체질량 지수의 장기적인 변화

정사준,권영란,송강훈 대한소아신경학회 2010 대한소아신경학회지 Vol.18 No.1

Purpose:The objective of this prospective study is to assess changes in body mass index(BMI, weight in kilograms/height in meters2) according to age and dosage on epileptic children treated with topiramate. Methods:From January 2006 to December 2008, prospective studies have been performed on 63 children with epilepsy aged below 15 old who had been treated with topiramate. Patients were classified into 3 groups according to age: 2-5 years as a group 1; 6-10 years as a group 2; 11-15 years as a group 3;, and classified into 2 groups according to dosage: from 2 to 5 mg/kg/day as group A, more than 5 mg/kg/day to 8 mg/kg/day as group B. We have checked BMI of patients four times and evaluated the changes in BMI of each group. Results:BMI at initial presentation and follow-up periods of 6, 12, and 24 months is as follows: 16.3±1.25, 14.3±1.8, 14.2±2.4, and 15.7±2.1 in the group 1, 18.5±1.23, 15.2±1.24, 14.8±2.27, and 16.8±2.5 in the group 2, 21.6±2.31, 16.5± 2.17, 15.4±2.56, and 15.1±1.3 in the group 3. Comparing with group A and B is as follows: 19.3±2.35 and 18.1±1.89 at initial presentation, 15.5±2.45 and 15.1±1.15 at 6 months, 14.9±2.15 and 14.7±1.91 at 12 months, 15.9±1.28 and 16.0±1.12 at 24 months. Conclusion:The effect of topiramate on changes of BMI shows difference according to age. In groups of 2-10 years old, BMI was rebounded from lowest value after 12 months, however, in the group of 11-15 years old, BMI kept decreasing at 24 months. And dosage of topiramate does not affect to BMI significantly. 목 적:체중의 변화는 몇몇 항경련제의 장기간 투여 시 나타나는 주요한 부작용 중 하나이다. Topiramate는 성인과 소아의 부분 발작이나 전신 발작의 치료에 보조치료제나 단일치료제로 널리 사용되고 있는 항경련제로써, 체중감소를 일으키는 약물로 잘 알려져 있다. 본 연구에서는 소아에서 topiramate로 인한 나이에 따른 체질량 지수의 변화와 topiramate의 용량과 체질량 지수와의 관계를 2년 동안 관찰하여 그 상관성에 대해 알아보고자 하였다. 방 법:2006년 1월부터 2008년 12월까지 경희의료원 소아청소년의학과에서 간질을 진단 받고 항경련제 치료를 한 환자를 대상으로 나이와 topiramate 용량에 따라 환자를 분류하여 각 그룹의 체중과 체질량 지수를 연속적으로 측정하여 체질량 지수의 변화를 관찰하였다. 결 과:2-10세의 그룹에서는 12개월까지 체질량 지수가 지속적으로 감소하여 최저 수치에 도달했다가 24개월에는 초기 체질량 지수보다는 낮지만 최저 수치 보다는 상승한 소견을 보이는 반면, 11- 15세의 그룹에서는 24개월에 이르기까지 지속적으로 체질량 지수가 감소하는 소견을 보였다. 또한, 2-5 mg/kg/day을 최적 치료 용량으로 복용한 그룹과 5-8 mg/kg/day을 최적 치료 용량으로 복용한 그룹 모두에서 12개월까지는 체질량 지수의 감소를 보이다가 이후 증가하는 결과를 보였고, 모든 추적 관찰 기간에서 두 그룹 간에 유의한 차이가 없었다. 결 론:topiramate는 체질량 지수의 감소를 일으키며, 체질량 지수의 변화는 나이에 따라 차이가 있고, 나이가 적은 소아 환자보다 나이가 많은 소아 환자에서 체질량 지수의 감소가 더 현저하다. 또한, topiramate의 용량은 체질량 지수에 영향을 미치지 않는다.

건강한 성인에서 알콜섭취와 혈중지질농도와의 관계

조정진,강훈일,권선영 대한가정의학회 1999 Korean Journal of Family Medicine Vol.20 No.10

소아 재발성 중이염의 위험인자에 대한 연구

김은진,권영란,송강훈,장원녕,이진,장진근,차성호 대한소아감염학회 2010 Pediatric Infection and Vaccine Vol.17 No.2

Purpose : Recurrent otitis media (ROM) is usually defined as ≥3 distinct and well-documented episodes within 6 months or ≥4 episodes within 12 months. ROM is sufficiently important to warrant consideration of chemoprophylaxis, tympanostomy tube placement. There also is evidence that children with ROM are at risk for both hearing loss and speech delay. However,studies of ROM have been notably insufficient. In addition, even though environmental, racial, and sociocultural differences can affect risk factors, few studies have been conducted with regard to recurrent otitis media in Korea. Methods : This study was conducted from July 2009 to January 2010 with infants and children who were younger than 60months old, who visited the out-patient clinics at Han-Il General Hospital and Kyunghee University Hospital. Data were collected by interview using a pre-formed sheet. Among a total of 892 infants and children, 457 were excluded, and the remaining 435 were allocated to 104 with ROM and 331 as a control group. Results : Attendance at daycare centers (P <0.001, OR=2.85), allergic rhinitis (P =0.026, OR=2.32), past history of bronchiolitis (P =0.003, OR=2.33), and low socioeconomic status (P =0.005, OR=2.00) were found to have a close significant correlation with ROM. Risk factors such as sex, having a sibling, breast-feeding, use of pacifiers, atopy, pneumococcal vaccination,influenza vaccination, smoking of parents, and indoor smoking are not relevant. Conclusion : Attendance at daycare centers, allergic rhinitis, past history of bronchiolitis, and low socioeconomic status have been identified as risk factors for ROM. 목 적:재발성 중이염은 말하기, 언어, 인지 능력 지연및 저하를 유발할 수 있으며, 청력 소실 혹은 손상을 초래할 수 있다. 또한 재발성 중이염을 앓는 소아들은 예방적 항생제 투여, 고막 절개와 튜브 삽입, 아데노이드 절제의 고려 대상이 된다. 하지만 재발성 중이염의 위험인자에 관한 연구는 매우 부족하며, 국내에서는 이에 관한연구가 아직까지 없다. 이에 저자들은 우리나라의 소아재발성 중이염의 위험인자들에 대해 알아보고자 하였다. 방 법: 2009년 7월부터 2010년 1월까지 한일 병원과경희의료원 소아청소년과 외래를 방문한 60개월 미만의소아를 대상으로, 104명의 재발성 중이염군과 331명의대조군을 대면조사를 통해 조사하였다. 성별, 모유수유,인공 젖꼭지 사용, 어린이집 이용, 알레르기 비염 병력,모세기관지염의 병력, 소득 수준, 부모 흡연, 집안에서의흡연, 폐구균 백신 및 인플루엔자 백신 접종력 등의 항목을 조사하였다. 각각의 위험인자와 재발성 중이염간의연관성을 확인하기 위해 카이제곱 검정을 통한 단변량분석을 시행하였고, 단변량 분석에서 의미 있었던 위험인자들 간의 교란변수를 보정하기 위해 이분형 로지스틱회귀분석을 통한 다변량 분석도 시행하였다. 결 과:단변량 분석에서는 어린이집 이용, 알레르기 비염, 아토피, 모세기관지염, 부모 흡연, 집안에서의 흡연,낮은 사회경제 상태가 의미 있는 위험인자였다. 하지만폐구균 백신 접종은 통계적 유의성이 없었다. 교란변수를 보정한 다변량 분석에서는 아토피, 부모 흡연, 집안에서의 흡연을 제외한, 어린이집 이용(P <0.001, OR=2.85), 알레르기 비염(P =0.026, OR=2.32), 모세기관지염(P =0.003, OR=2.33), 낮은 경제상태(P =0.005,OR=2.00)가 의미 있는 독립적인 위험인자였다. 결 론 : 알레르기 비염과 모세기관지염의 병력이 있고,낮은 사회경제 상태에 있으며, 어린이집을 이용하고 있는 소아일수록 재발성 중이염에 걸릴 위험이 높았다.

都市街路의 遲滯度推定에 관한 硏究

임채문,권강훈,이주호,김태형 대구대학교 과학기술연구소 2001 科學技術硏究 Vol.8 No.1

This study suggested input variables whose effects have been considered by adjusting various input variables in the TRANSYT-7F and NETSIM, the Simulation programs employed in calculating the delay time at street sections. The results can be summarized as follow. 1. Among the input variables in the TRANSYT-7F needed to calculate the delay time at street sections, the excluded are those which effect the most on time delay, such as bus stops, pedestrian crossings and on/off ramps. Among the input variables the most affecting factors are Saturation flow rate and time delay whose suggested quotients are well summarized in the text of this study. 2. There are variables which affect the change of time delay in the NETSIM, such as bus stop, pedestrian crossing, bus appearance period, and departure time delay. This study did the Simulation program using those variables except pedestrian crossing because, as the result of the correlation analysis suggests, there is a strong correlation between bus stop and pedestrian crossing. In this study, the survey had been done in the morning and afternoon except the Peak time, so heavily congested sections were excluded. And both sides of three street sections were surveyed. Therefore, there should be further studies on heavily congested situations and many other street sections.

통근교통 수단선택에 대한 연구

임채문,권강훈,구경남 대구대학교 과학기술연구소 1999 科學技術硏究 Vol.5 No.5

The growth of auto ownership which was resulted by a rapid growth of economy and population caused a terrible transportation problem. This problem will not be improved by the supply of transportation facility. These days, it is natural for every foreign country to give a priority to the public transportation. Namely, it is necessary that the policy for travellers to attract from auto to public transportation is needed. Therefore, the purpose of this study is to find a basic idea for attracting auto users to public transportation. This study is largely divided into 3 parts. First, a travel mode choice model was estimated by using which is all the sample. Second, the mode choice models were estimated with the market segmentation divided by residential and work location. Third, the policy analysis was performed by using the estimated model.

도로설계요소에 대한 운전자 인식도 분석

임채문,박준,권강훈,홍익상 대구대학교 과학기술연구소 1998 科學技術硏究 Vol.5 No.3

This study presents fundamental data to design for the safe and comfortable road. and to reduce traffic accidents by performing cognition analysis and Factor Analysis of drivers. The results obtained are summarized as follow : 1. According to analysis of investigated road design elements, most drivers have low cognition level in alinement elements of road design. So drivers have to get more information than now about alinement elements of road design, 2. When we design road, it is proved that alinement as well as safety is so important to drivers. Therefore we should design road considering drivers` characteristics.

순환정지와 초저체온 및 Barbiturate를 이용한 거대 뇌동맥류 수술의 마취

김상태,배진호,강훈,임승운,민병상,권필순 대한마취과학회 1998 Korean Journal of Anesthesiology Vol.35 No.4

The surgical and anesthetic management for giant cerebral aneurysm is difficult because of their great size or lack of an anatomic neck. Recently, total circulatory arrest, profound hypothermia using cardiopulmonary bypass and the cerebral protection of barbiturate are able to manage the difficult cerebral aneurysm operation due to the ease of the surgical approach and the decreased post operative neurological injury. These techniques were successfully utilized in the patient of the diamerer-3 cm sized giant cerebral aneurysm located at the bifurcation between the right internal carotid artery and the anterior cerebral artery, and the surgical and anesthetic considerations are reviewed. (Korean J Anesthesiol 1998; 35: 767∼771)

적정 예비 신호등 설치에 관한 연구

임채문,박관,권강훈,정만표 대구대학교 과학기술연구소 1998 科學技術硏究 Vol.5 No.4

In this study, the crosswalk at Hayaong-Yungchun arterial located in Kyungbuk province were chosen as the subject, and the reaction patterns of drivers were analyzed by the survey of the approach velocity of cars, know-reaction time and the geometric structure of crosswalk, and the substitute about the installation of pre-traffic signal at moderate distance for the prevention of the disturbing zone (dilemma zone, option zone) to drivers' pass-stop decision at the yellow-signal-situation was presented. The results are summarized as follows 1. The know-reaction time which is applied to the calculation of the yellow signal time is 1 second in korea generally, but the average time was 1.67 second and the standard variation was 0.38 second at 95 samples of the analyzing area. 2. The comparison between the calculation formula of the yellow signal time which is used in korea and the actual time has 1 second difference.