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조직 재생유도술에 사용되는 e-PTFE 및 collagen막에 부착되는 치주세균과 항생제 감수성에 대한 연구
임효정,김성조,최정임,Im, Hyo-Jeong,Kim, Surg-Jo,Choi, Jeom-Il 대한치주과학회 1994 Journal of Periodontal & Implant Science Vol.24 No.3
The comparative study on the predominant cultivable periodontopathic bacteria were done 2 weeks after the application of the e-PTFE membrane and collagen membrane in the controlled tissue regeneration procedures. The purpose of the present study also included the antibiotic susceptibility test (ciprofloxacin, tetracycline, clindamycin) of these cultured organisms. 0.1% chlorhexidine mouthwash (10ml twice/day for 6 weeks) and systemic doxycycline (200mg/day for 2 weeks) were administered for supragingival and subgingival plaque control respectively. Four clinical isolates of A.a. from 2 patients were found to be resistant to tetracycline which were susceptible to clindamycin and ciprofloxacin. One isolate of W.r. and two unidcntified microorganisms were resistant only to clindamycin and one isolate of NID BPB and E.c. and two isolates of unidentified microorganisms were resistant only to ciprofloxacin. Overall susceptibility of tested microorganisms to ciprofloxacin, tetracycline and clindamycin were 85%, 77% and 89% respectively. The results indicated no significant differences in the percentage of cultivable periodontopathic bacteria between the two membranes, and also the microorganisms resistant to tetracycline after systemic administration of doxycycline turned out to be susceptible to either ciprofloxacin or clindamycin.
장애형제를 둔 비장애형제의 질적 연구 동향 및 향후 과제
임효정,김민지,Lim, Hyo-jong,Kim, Min-Ji 한국융합학회 2021 한국융합학회논문지 Vol.12 No.7
본 연구는 장애 형제를 둔 비장애 형제들의 경험에 대한 질적 연구의 동향을 분석하기 위해 최근 10년 동안 국내 학술지 중 등재지 또는 등재후보 학술지에 발표된 논문을 RISS 등 검색사이트를 통해 분석하여 17편의 논문을 선정하였다. 이후 17편의 논문을 연구 참여자, 연구 방법, 연구 주제 등에 따라 분석하였다. 그 결과, 질적 연구 방법 중 현상학적 연구 방법의 연구가 가장 많이 시도되었으며 참여자의 연령은 20대를 포함한 연구가 많았다. 또한 비장애형제의 출생순위나 성별, 장애 유형 등을 구분하지 않는 연구들이 많아 향후 이를 세분화한 연구가 필요함을 알 수 있었다. 향후 연구과제에 주는 시사점은 다음과 같다. 비장애 형제의 경험을 심층적으로 탐구하고 이해하는 현상학적 연구를 넘어 이론화를 시도하여 실제 정책에 반영할 수 있는 근거이론 등 다양한 연구 방법이 시도되어야 하며 참여대상의 세분화도 이루어져야 할 것이다. 또한, 비장애 형제들이 원하는 동질적 집단에 관한 연구와 지원도 요청되고 있다는 것을 확인하였다. This study examined the current trend of the qualitative researches on the experiences of individuals who have siblings with disabilities. This study analyzed 17 research articles that either have been published in journals or nominated during the recent ten years, attempting to suggest future directions of the research on siblings who have siblings with disabilities. This study analyzed 17 research papers examining their participants, research methods, and research topics. The results of the previous literature analysis are the followings. Phenomenological approach is the most frequently used research method and normally developing siblings who were in their 20s participated in the researches most. As most research papers did not consider the normally developing siblings birth order, sex, and types of disabilities, future researches will need to specify these variables. The results of this study suggest the followings. Researchers have tried to investigate and understand the experience of the individuals who have siblings with disabilities, using phenomenological research method. Future research should go beyond the phenomenological research to developed theories that can affect the government policies, employing various research methods with specified participants. Further, this study has also identified that the individuals who have siblings with disabilities wanted to be identified as a separate cohort that needs to be researched and receive support.
The Dynamic Nature of Learner Motivation: A Cross-sectional Study in Korea
임효정 한국외국어대학교 외국어교육연구소 2020 외국어교육연구 Vol.34 No.1
The study is twofold; to update the literature on English language learners’ motivation in Korea and to examine any changes in learner motivation between high school and university students. A total of 385 Korean students (high school students = 184, university students = 201) completed the learner background and motivation questionnaires in 2017-2018. The collected data were submitted to the structural equation modeling (SEM) analysis as well as an independent t-test to inspect any group differences. Results showed that university students reported a higher level of ideal L2 self, more positive attitudes toward learning English, and more motivated behavior than high school students. However, the two groups did not differ in terms of the ought-to L2 self, family influence and prevention-based instrumental motivation. The SEM analysis revealed that ought-to L2 self was a significant predictor of motivated behavior in the high school group (p = .017) but not in the university group (p = .428). In both groups, attitudes toward learning English, mediated by the ideal L2 self, turned out to be the strongest predictor of motivated behavior. Further discussed are the socioeducational reasons for the differences and the pedagogical implications of the findings.
Comparison of Inhibitory Effects between Enalapril and Losartan on Adrenal Catecholamine Secretion
임효정,고영엽,임동윤 대한고혈압학회 2014 Clinical Hypertension Vol.20 No.2
Background: The present study was attempted to compare enalapril, an angiotensin-converting enzyme inhibitor withlosartan an angiotensin II (Ang II) receptor blocker in the inhibitory effects on the secretion of catecholamines (CA) fromthe perfused model of the rat adrenal gland. Methods: The adrenal gland was isolated and perfused with Krebs-bicarbonate. CA was measured directly by using the fluorospectrophotometer. Results: Both enalapril and losartan during perfusion intoan adrenal vein for 90 minutes inhibited the CA release evoked by acetylcholine (ACh), 1.1-dimethyl-4-phenyl piperazinium(DMPP, a selective Nn agonist), high K+ (a direct membrane-depolarizer), 3-(m-chloro-phenyl-carbamoyl-oxy-2-butynyltrimethylammonium (McN-A-343, a selective M1 agonist), and Ang II in a time-dependent manner. Also, in the presence ofenalapril or losartan, the CA release evoked by veratridine (an activator of voltage-dependent Na+ channels),6-dimethyl-3-nitro-4-(2-trifluoromethyl–phenyl)-pyridine-5-carboxylate (BAY-K-8644, an L-type Ca2+ channel activator),and cyclopiazonic acid (a cytoplasmic Ca2+-ATPase inhibitor) were significantly reduced. Based on the same concentrationof enalapril and losartan, for the CA release evoked by ACh, high K+, DMPP, McN-A-343, Ang II, veratridine,BAY-K-8644, and cyclopiazonic acid, the following rank order of inhibitory potency was obtained: losartan > enalapril. Inthe simultaneous presence of enalapril and losartan, ACh-evoked CA secretion was more strongly inhibited compared withthat of enalapril- or losartan-treated alone. Conclusions: Collectively, these results demonstrate that both enalapril andlosartan inhibit the CA secretion evoked by activation of both cholinergic and Ang II type-1 receptors stimulation in theperfused rat adrenal medulla. When these two drugs were used in combination, their effects were enhanced, which may alsobe of clinical benefit. Based on concentration used in this study, the inhibitory effect of losartan on the CA secretion seemsto be more potent than that of enalapril.