정상 면역가능을 가진 환자에서 발생한 침습성 폐진균증 1예

임영희,천은미,김호철,서지영,박정웅,권오정,이종헌,이재영,이경수,한정호,Lim, Young-Hee,Cheon, Eun-Mee,Kim, Ho-Cheol,Suh, Gee-Young,Park, Jeong-Woong,Kwon, O-Jung,Rhee, Chong-H.,Lee, Jae-Young,Lee, Kyung-Soo,Han, Jeong-Ho 대한결핵및호흡기학회 1998 Tuberculosis and Respiratory Diseases Vol.45 No.1

Invasive pulmonary aspergillosis is a disease occuring predominantly in patients with defects in immunity such as neutropenia, hematologic malignancies or with defects in cell-mediated immunity. The isolation of Aspergillus from respiratory tract of normal host usually signifies tracheobronchial colonization, making this diagnosis difficult. There are isolated case reports occuring in normal hosts but most of them were diagnosed postmortem at autopsies indicating that early diagnosis of invasive aspergillosis in normal host is difficult. We describe here a case of invasive aspergillosis in a immunocompetent host diagnosed by lung biopsy which was successfully treated with Amphotericin-B. Invasive pulmonary aspergillosis should be included as one of the differential diagnosis if a patient with pneumonic consolidation does not respond to usual therapy, even if the patient does not have any defect in immunity.

대전 ${\cdot}$ 충남지역 단체급식소 조리종사자의 위생관리실태조사

임영희,곽현옥,Lim, Young-Hee,Kwak, Hyun-Ok 한국식생활문화학회 2006 韓國食生活文化學會誌 Vol.21 No.4

This study was conducted to evaluate sanitary managment practices of institutional foodservice employees in Daejeon and Chungnam areas, and to suggest a guideline for an effective safety & sanitary managment of the institutional foodservice. The subjects consist of 782 employees in 80 institutional foodservice, respectively. The collected data was processed using the SPSS V.10.0 package for descriptive analysis. The results of this study were summarized as follows. The employees were female(97.2%), over 41 age(68.1%), high school(51.0%), less than 1-5 years(52.8%) of total career in the institutional foodservice. Employment status was contract(64.2%) and cook's certification w3s not applicable(80.1%). The institutional foodservice was over 1,000 number(65.0%) of average serving per day and operations format was direct(69.6%) management and 11-20 number of employees for cooking were 58.2%. Employees(96.0%) were received sanitation training and 82.4% of them have been monthly educated. Sanitation training instructor was dietitian 91.6%. The rating of sanitary management practices was food handling 4.36/5.00, food products management 4.32/5.00, personal hygiene 4.31/5.00, equipments and tools handing 4.18/5.00. The employees, who were educated in the sanitation training, presented significantly higher rates of the sanitary management practices than of the uneducated employess. Therefore, the institutional foodservice operations will have to pay special attention to sanitation training program of the employees. The suitable methods of sanitation training must be developed to improve the practical use of sanitary management by employees and institutional foodservice. Also, to enhance these practices, it is necessary to establish the countermeasure to care for safety & sanitary management of the institutional foodservice.

우리나라에서 유통되고 있는 수생식물의 종류 및 화훼장식품에서의 활용 실태 분석

임영희(Young Hee Lim),김원진(Won Jin Kim),오욱(Wook Oh),김규원(Kiu Weon Kim) 인간식물환경학회 2011 인간식물환경학회지 Vol.14 No.1

We investigated the kinds and uses of currently-distributed species of aquatic plants (hydrophytes) from 2 big farms and 21 wholesalers located in the Capital region and metropolitan areas in Korea and the actual conditions of their ornamental uses from 130 floral design works. Hydrophytes domestically distributed were 82 species including emergent (43.9%), floating-leaved (19.5%), submerged (21.9%), and free-floating (14.6%) plants. Most hydrophytes were used for garden plants (78 species, 91.5%) and potted plants (76 species, 92.6%), while only 19 species (23.1% of 82 species) were used as cut plants. More than 90% of hydrophytes used as cut plants for flower design were four emergent hydrophytes including Equisetum hyemale, Typha orientalis, Phragmites australis, and Thalia dealbata, and two floating-leaved hydrophytes including Nelumbo nucifera and Nymphaea tetragona. Portions of cut branches, cut flowers, and cut foliage in cut plants were 53.9, 24.6, and 21.5%, respectively.

유전자 알고리즘과 신경망의 융합을 이용한 퍼지 추론 모델의 최적화

임영희(Young Hee Lim),박대희(Dae Hee Park) 한국정보과학회 1995 정보과학회논문지 Vol.22 No.5

Cao의 퍼지 추론은 언어적인 용어의 이해와 언어적인 용어간의 관계 정도를 이용한 퍼지 관계 행렬을 사용함으로써 Zadeh의 퍼지 추론에서 문제점으로 제기된 퍼지 함축 연산자의 선택 문제를 해결하였으며, Zadeh의 퍼지 추론보다 우수한 성능을 보임이 입증되었다. 그러나 Cao의 퍼지 추론 역시 퍼지 관계 행렬이 전문가의 선험적인 지식에 의해 결정되며, 시스템이 복잡할수록 전문가로 부터 최적의 퍼지 관계 행렬을 얻을 수 없다는 문제점을 안고 있다. 더 나아가 전문가에 의해 결정되는 퍼지 소속 함수 역시 시스템의 성능을 크게 좌우한다. 따라서 본 논문에서는 유전자 알고리즘을 이용하여 퍼지 관계 행렬과 조건부와 결론부의 소속 함수를 조정한다. 또한 Cao의 퍼지 추론을 전방향 신경망의 구조로 표현하여 오차 표면을 따라 기울기 강하를 수행하는 기울기 강하 유전 연산자를 수행함으로써 유전자 알고리즘에 지역적 미세 조정을 위한 메카니즘을 제공한다. 제안된 방법의 유용성을 보이기 위해 DC series motor에 적용해 본다. Recently, Cao, Kandel and Li have proposed a New Fuzzy Reasoning Method (NFRM, for short) which turned out to be superior to the Zadeh′s Fuzzy Reasoning Method (FRM, for short). However, in the NFRM, the fuzzy relation matrix, determined by a human expert according to his/her experiences, plays an important role, but may be difficult to extract optimally from an expert, particulary as the system increases in complexity. Moreover, a change in the fuzzy membership function may alter the performance of the fuzzy system significantly. Therefore, to alleviate some of the drawbacks associated with the NFRM as pointed in the above, in this paper, the genetic algorithm is to be incorporated in the context of the NFRM in the loop whose function is to search for optimal fuzzy relation matrix and fuzzy membership functions simultaneously. In addition, the particular genetic algorithm we used is supplemented by a local fine-tuning mechanism with executing the gradient descent genetic operator. We also report on the application and performance analysis with a direct current series motor.

네트워크 분석을 활용한 온라인 리뷰의 호텔 유형별 선택속성 연구

임영희(Lim, Young-Hee) 한국호텔외식관광경영학회 2023 호텔경영학연구 Vol.32 No.6

This study used data mining techniques based on Korean reviews left by domestic customers who visited business hotels, resort hotels, airport hotels, and Hanok hotels, then identified frequent words using frequency analysis and TF-IDF analysis. In addition, highly influential words were identified directly and indirectly using network centrality analysis, and hotel selection attributes by type were derived through CONCOR analysis. As a result of frequency analysis, words such as ‘room’, ‘breakfast’, ‘kindness’, ‘satisfaction’, ‘service’, and ‘good’ showed high frequency. As a result of network centrality analysis, words such as ‘room’ were found to have a strong influence. All types of hotel selection attributes were classified into four categories: ‘service (including price and F&B)’, ‘facilities’, ‘location’, and ‘leisure and experience’. In the case of business hotels, elements of ‘service’ selection attributes accounted for a large proportion, and elements of ‘leisure and experience’ selection attributes appeared frequently regarding resort hotels. In addition, ‘location’ attribute words had the highest proportion as selection attributes for airport hotels, and ‘facility’ words related to tradition were highly prevalent for Hanok hotels. As a result of this study, since the number of Hanok hotels is small compared to the customers preference, the central and local governments must make bold investments to publicize unique cultural sentiments and values. Hotel customers who want to enjoy a vacation in a hotel choose a hotel based on service, price, special facilities, location, and reviews, rather than hotel type. Therefore, the boundaries between hotel types excluding Hanok hotels are fading, which will intensify competition to attract Koreans.

Multiplex Polymerase Chain Reaction Assay for Simultaneous Detection of Candida albicans and Candida dubliniensis : Multiplex PCR을 이용한 C. albicans 및 C. dubliniensis의 감별 검출법

임영희(Young-Hee Lim),이도현(Do-Hyun Lee) 고려대학교 보건과학연구소 2001 보건과학논집 Vol.27 No.2

Oxyresveratrol의 기원, 생합성, 생물학적 활성 및 약물동력학

임영희(Young-Hee Lim),김기현(Ki-Hyun Kim),김정근(Jeong-Keun Kim) 한국식품과학회 2015 한국식품과학회지 Vol.47 No.5

Oxyresveratrol (trans-2,3,4,5-tetrahydroxystilbene) has been receiving increasing attention because of its astonishing biological activities, including antihyperlipidemic, neuroprotection, antidiabetic, anticancer, antiinflammation, immunomodulation, antiaging, and antioxidant activities. Oxyresveratrol is a stilbenoid, a type of natural phenol and a phytoalexin produced in the roots, stems, leaves, and fruits of several plants. It was first isolated from the heartwood of Artocarpus lakoocha, and has also been found in various plants, including Smilax china, Morus alba, Varatrum nigrum, Scirpus maritinus, and Maclura pomifera. Oxyresveratrol, an aglycone of mulberroside A, has been produced by microbial biotransformation or enzymatic hydrolysis of a glycosylated stilbene mulberroside A, which is one of the major compounds of the roots of M. alba. Oxyresveratrol shows less cytotoxicity, better antioxidant activity and polarity, and higher cell permeability and bioavailability than resveratrol (trans-3,5,4-trihydroxystilbene), a well-known antioxidant, suggesting that oxyresveratrol might be a potential candidate for use in health functional food and medicine. This review focuses on the plant sources, chemical characteristics, analysis, biosynthesis, and biological activities of oxyresveratrol as well as describes the perspectives on further exploration of oxyresveratrol.

INHIBITORS OF THE ENZYME RELATED POST - TRANSLATIONAL MODIFICATION OF PROTEIN

임영희(Young Hee Lim),(Robert R . Rando) 생화학분자생물학회 1997 생화학분자생물학회 춘계학술발표논문집 Vol.- No.-

국제결혼 이주여성의 부모역할 인지와 경험에 관한 현상학적 연구

임영희(Lim Young hee),이병환(Lee Byung hwan),권인탁(Kwon In tak) 한국열린교육학회 2014 열린교육연구 Vol.22 No.4

이 연구는 부모교육프로그램에 참여한 국제결혼 이주 여성의 부모역할 인지 및 그 경험을 현상학적으로 탐구하고자 하였다. 이를 위한 연구방법은 양육효능감, 역할만족감, 양육태도 및 행동 등에 관한 심층면접과 현상학적 관찰로 실시되었다. 연구 결과를 보면, 대부분의 참여자들은 낮은 양육효능감을 갖고 있었고, 역할 만족감에서도 자녀와의 관계형성 및 의사소통의 부재 등으로 인해 역할 만족도 낮았으나, 프로그램 참여 후 다소 개선되었음이 확인되었다. 그런데 양육태도 및 행동에 대한 이주여성의 부모역할의 경험은 대부분 피동적이고 보다 적극적이지 못했다. 그 밖에 결과는 가정의 유형 및 참여한 프로그램(지역 및 기관)에 따라 부모역할에 대한 인지 정도와 양상이 다소 다르게 나타났으며, 프로그램 제공자의 역할 기대와도 차이를 보였다. 향후에는 이주여성의 실천가이드 및 부모역할 수행의 코칭, 멘토링 등의 프로그램 내용이 추가되어야할 필요가 있다. This study aimed to explore married immigrant mothers' perceptions and experiences of Parental Role by Phenomenological Research methods. In order to do so, research methods were used during in-depth interviews and phenomenological observation related to child-rearing efficiency, role satisfaction, and child-rearing behavior and attitudes was implemented. Based on the research findings, the following conclusions were made: First, most of the married immigrant mothers had low child-rearing efficiency. Second, role satisfaction was low due to insufficient relation formation and communication. However these were improved slightly after participating in the program. Third, married immigrant mothers' experiences of parental role were passive. Finally, the programs they participated in, the perception and tendency of parental roles were different according to regions and institutions. In addition, they need practice guides and programs related to married immigrant mothers' coaching and mentoring for positive parental roles.

옹기 화병이 절화 거베라의 수명 및 미생물 증식에 미치는 영향

임영희(Young Hee Lim),오욱(Wook Oh) 한국원예학회 2011 원예과학기술지 Vol.29 No.2

To examine the availability of onggi (earthenware) as a floral vase, we compared the vase life of cut gerberas (Gerbera jamesonii) with generally used vases made of glass and porcelain. After holding cut gerbera ‘Honeymoon’ and ‘Golden Time’ in vases made of glass, porcelain, and onggi containing holding solution (tap water or preservative solution), vase life, fresh weight, and water uptake of cut flowers, and total number of microbes in holding solution were collected. In onggi vase, vase life of both the cultivars was longer than the other vases and floral preservative prolonged vase life compared with tap water. Cut gerberas applied with preservative solution in onggi vase maintained their ornamental value for more than 14 days. Cumulative water uptake by cut gerberas was greatest in onggi vase, where ‘Honeymoon’ and ‘Golden Time’ absorbed water by 19.2 and 15.8 mL, respectively, for 10 days. Fresh weight of cut flowers in onggi vase was greater than those of the others, and the preservative solution delayed the reduction of fresh weight compared with tap water. Especially, onggi vase with preservative solution maintained 89% of the initial fresh weight at the 8th day of the treatments due to smooth water uptake with comparison with 71% in porcelain. Total number of microbes in the holding solution was smallest in onggi vase. At the 8th day, microbes number in onggi vase was 435 cfu/mL, that was 20-30% level of those of glass and porcelain vases. In conclusion, onggi vase inhibited microbial proliferation in holding solution, maintained water uptake by cut flower, and delayed bending of flower stalks due to vascular blockage, and then prolonged vase life in gerbera. Therefore, onggi with numerous micropores will be a good material for flower vase and preservative solution can improve its function.