영재 학생들을 위한 과학사-CPS 수업 모형을 활용한 분자생물 영역 수업 프로그램의 개발 및 적용

이주현 ( Ju Hyun Lee ),이미숙 ( Mi Sook Lee ),주희영 ( Hee Young Ju ),이길재 ( Kil Jae Lee3 ) 경북대학교 과학교육연구소 2011 科學敎育硏究誌 Vol.35 No.2

This research was aimed to develop and apply the molecular genetics teaching program based on the history of science and creative problem solving model (HS-CPS model) for gifted students. Based on the strategies of creative problem solving and scientific theory development, the HS-CPS teaching program were developed. This program was applied to 8 first and second graders of the special class for invention activity in a high school. Creative problem solving ability in science and the understanding of DNA and gene concept were tested in pre and post of 12 lessons. The results were as follows: First, creative problem solving ability in science was improved meaningfully. Second, HS-CPS teaching program was effective in the understanding of DNA and gene concepts. Third, the students responded positively to the program evaluation questionnaire.

이종골을 이용한 상악동 측벽거상술과 동시 식립한 임프란트에서 안정성에 대한 공진 주파수 분석

이주현,민현기,이진숙,김명래,강나라,Lee, Ju-Hyon,Min, Hyun-Gi,Lee, Jin-Sook,Kim, Myung-Rae,Kang, Na-Ra 대한악안면성형재건외과학회 2008 Maxillofacial Plastic Reconstructive Surgery Vol.30 No.6

In posterior maxilla, it is difficult to achieve primary stability of implants due to sinus pneumatization, alveolar bone loss, and low bone quality. The accurate and objective primary stability assessment is important for good prognosis of implants. Purpose: The aim of this study was to assess the primary stability of the non-submerged, internal type implants with maxillary sinus augmentation using deproteinized bovine bone mineral by a resonance frequency analyzer, when residual alveolar bone height is under 8mm Materials and methods: A total of 20 implants was placed into 5 grafted maxillary sinuses in 5 patients. Deproteinized bovine bone mineral (Bio-$Oss^{(R)}$) was used as graft material. SS II implants (diameter 4.1mm, and length 11.5mm, SLA suface)) were placed. All of the patients received maxillary sinus graft procedure by 1-step technique. Residual bone height was $1.3{\sim}7.8mm$ (mean 4.4mm) measured by panorama radiography. After implant placement, RFA was measured at 4,8,12,20 weeks. The results were divided into 2 groups; RFA value under 4mm and over 5mm of bone height. It was statistically analyzed. Results: 1. The primary stability of implants was increased with time 2. The RFA value was above 65 ISQ at 12 weeks 3. There was no correlation between RFA and residual alveolar bone height in maxillary sinus augmentation by 1-step technique. Conclusion: 1-step surgical procedure is a feasible option for patients with as little as 4mm residual alveolar bone height, when utilizing non-submerged, internal type implants with xenografts.

계지가대황탕(桂枝加大黃湯) 투여 이후 호전된 턱 주위 모낭염 치험 1례

이주현,조은희,경다현,박지원,박민철,Lee, Ju-Hyun,Jo, Eun-Heui,Kyung, Da-Hyun,Park, Ji-Won,Park, Min-Cheol 대한한방안이비인후피부과학회 2021 한방안이비인후피부과학회지 Vol.34 No.3

Objectives : This study aims to report a case of chin area folliculitis improved by oral administration of Gyejigadaehwang-tang. Methods : The patient of this study visited our hospital with purulent lesions accompanied by erythema, papules and pustules around the chin area that have recurred over 10 years. Based on the patient's tendency of chills and constipation, Gyejigadaehwang-tang was prescribed. Results : About a month later, most of the skin symptoms improved (Total Folliculitis Symptom score 11→2), and only brown marks and mild erythema due to pigmentation after inflammation, were observed. Symptoms related to constipation also improved from 13 to 4 points. In the follow-up process after the treatment, It was confirmed that the symptoms of folliculitis did not recur. Conclusions : After taking Gyejigadaehwang-tang for a month, purulent lesions generally improved. Symptoms related to constipation also diminished, allowing regular bowel movements once a day.

한약재의 미생물허용한도 설정을 위한 모니터링(I)

이주현,전원경,고병섭,천진미,이아영,김호경,Lee, Ju-Hyun,Jeon, Won-Kyung,Go, Byoung-Seob,Chun, Jin-Mi,Lee, A-Yeong,Kim, Ho-Gyoung 한국한의학연구원 2006 한국한의학연구원논문집 Vol.12 No.1

한약재는 생산, 가공, 유통과정에서 적절한 보관. 관리가 이루어지지 않으면 미생물 증식 가능성이 크고 이로 인한 부패나 변질이 우려되며 한약 품질 저하를 가져올 수 있다. 한약재 미생물허용한도에 대한 각 나라별 규격기준을 보면 유렵약국, 도일약국에서는 호기성균의 미생물오염한도(microbial contamination limit)를 10 CFU/g 이하로 규격화하고 있다. 또한 미국약국 NF(US phamacopeia & National Formulary)에서는 생약의 미생물 한도치를 유럽약국과 같은 정도의 규격설정을 하고 있다. 특히 일본의 경우 일본약국방(日本藥局方) 및 국방외생약규격집(局方外生藥規格集)에 의해서 한약의 품질을 유지하고 있고, 미생물학적 품질관리 실태조사가 체계적으로 이루어지고 있다. 본 연구에서는 3개 지역에서 각각 1곳의 약업사를 정하여 대상품목 총 30종을 선정하였다. 실험의 재료는 문헌과 자료조사에 의해 미생물에 의한 오염이 용이한 품목 18종, 육진약(六陳藥)에 속하는 6종, 그리고 육미지황환을 구성하는 6종을 구입하여 대한약전 8개정의 미생물한도 시험법에 따라 시험하였다. 한약재에 대한 미생물 오염 실태조사를 통하여 미생물 허용한도를 설정하는데 기초 자료로 제시하고자 한다. 한약재 미생물 오염 실태조사 결과 WHO 미생물한도 기준을 적용하였을 때, 전체적으로 진균의 오염이 높은 경향을 보였고 향후 한약재에 대한 미생물오염도 모니터링을 지속적으로 하여야 할 것으로 사료된다. Objectives : This study has attempted to establish an organized system for the microbiological quality of raw materials which are important factors in preparing the standard for microbial limits. Methods : This study has first set up microbial contamination limit test. total aerobic microbial count and total fungi count, int accordance with testing method of the Korea Pharmacopeia 8th edition in order to establish an inspection standard for microbial contamination. Results : The microbial contamination of 18 items that are highly prone to contamination by three regions(Seoul, Daejeon, Gyeongsangbuk-do), As a result, Morus alba Linne and Rehmannia glutimosa Liboschitz var. purpurea Makino showed as high contaminated by WHO's Microbial Contamination Limit standard. In case of Yukjin medicine in the Theory of Herb Medicinal Properties, total bacterial contamination rate showed as 17.7%, total fungal contamination rate showed as 41.2% and total aerobic mircobial count and total fungi count on Ephedra sinica Stapf. Pinellia ternate Breitenbach, Evodia officinalis Dode showed as high measured. The microbial conatmination rate materials which make up Yukmijihwanghwan were mostly high therefore the total aerobic microbial count was measured as high in case of Yukmijihwanghwan, the characteristics about microbial contamination strain is to be researched. Conclusions : By combining the basic data and experimental results related to microbial contamination of herb medicine, the most ideal storage standards for herb medicine has been attempted to be presented.

황련아교탕(黃連阿膠湯) 투여로 호전된 만성 동전 모양 습진 1례

이주현,이상배,조은희,박민철,Ju-Hyun Lee,Sang-Bae Lee,Eun-Heui Jo,Min-Cheol Park 대한한의학회 2024 대한한의학회지 Vol.45 No.1

Objectives: This study aims to report a case of chronic nummular dermatitis improved by Hwangryunagyo-tang. Methods: The patient in this study was a 15-year-old female, who visited our hospital with symptoms such as redness, erythema, papule, excoriation, scale, exudation, crusting, lichenification, and pruritus of the extremities and trunk. Considering that the skin lesions were coin-shaped and persisted for more than 6 months, the patient's symptoms were diagnosed as chronic nummular eczema. Based on the patient's symptoms and overall condition, Hwangryunagyo-tang was prescribed. Results: Approximately 4 months after administration of Hwangryunagyo-tang, the exudate disappeared, and overall skin symptoms improved, from objective score 33.7 to 6.6, leaving only slight scale, dryness, and pigmentation. As the pruritus of the skin lesion decreased from numeric rating scale 8 to 1, the patient's sleeping condition also improved from numeric rating scale 9 to 0. Conclusion: This study is significant in that the symptoms of chronic nummular dermatitis were effectively improved after administration of Hwangryunagyo-tang.

건설 신기술의 원가산정기준 개선방안에 대한 연구

이주현,태용호,백승호,김경민,Lee, Ju-hyun,Tae, Yong-Ho,Baek, Seung-Ho,Kim, Kyoungmin 한국건설관리학회 2022 건설관리 : 한국건설관리학회 학회지 Vol.23 No.5

국내 건설기술의 발전을 도모하고 국가경쟁력을 제고하기 위한 목적으로 1989년 도입된 건설 신기술 지정제도는 심사과정에서 신기술의 원가계산서를 검토하고, 설계·시공 공사비, 유지관리비 등 비용절감효과와 공사기간 단축 효과를 경제성 항목으로 평가하고 있다. 그러나 이 과정에서 고유기술에 대하여 공사비산정기준관리기관과 신기술 개발자간의 의견차이가 빈번히 발생하고 있으며, 또한 현행 신기술에 대한 원가산정기준이 단위수량당 소요량만을 제시하는 방식으로 생산성에 대한 정보가 부재하여 기존 유사 기술과의 공사기간에 대한 객관적인 비교가 어려운 실정이다. 본 연구에서는 건설 신기술 심사 시 원가산정기준 검토절차와 심사기준, 신기술 품셈 작성방법 등 현황을 분석하고 해외 원가산정기준과 비교하여 현행 건설 신기술의 원가산정기준 개선방안을 제시하였다. 제시한 개선방안은 작업조 기반의 생산성 정보를 제공하고, 적용단가를 제시하여 원가기준의 투명성을 확보할 수 있도록 구성하였으며, 신기술의 특성을 고려하여 재료비와 기계경비에 대한 원가정보 역시 제공할 수 있도록 하였다. 본 연구의 개선된 원가산정 기준을 통해 발주자에게 신기술에 대한 원가정보를 현행보다 세부적으로 제공하고, 공사비 산정 과정을 보다 간소화함으로써 건설 신기술의 활용과 현장적용성을 향상시킬 수 있으리라 기대된다. The New Excellent Technology (NET) designation system, introduced in 1989 for the purpose of promoting the development of domestic construction technology and enhancing national competitiveness, reviews the statement of construction cost of new technologies. And the cost reduction effect such as design, construction, and maintenance cost and the effect of reducing the construction duration are evaluated as an evaluation criteria of economic feasibility. However, in this evaluation process, differences of opinion between the institution of construction cost estimating standard management and the new technology developer about unique technologies frequently occur. In addition it is difficult to objectively compare the construction duration with existing similar technologies because there is no information on productivity as the current cost estimating standards for new technologies only present the required amount per unit quantity. In this study, the current state of cost estimating criteria review procedure, evaluation criteria, and cost estimating standards establishment method were analyzed when screening for the designation of a new construction technologies, and compared with overseas cost estimating standards, measures to improve the cost estimating standards of current construction new technologies were suggested. Through the improved cost estimating standards of this study, it is expected that cost information on new technologies will be provided to clients in more detail than the current ones, and the availability and applicability of new construction technologies would be improved by simplifying the construction cost calculation process more.

딸림자료의 멀티미디어 데이터베이스 구축을 통한 이용 효율 제고에 관한 연구

이주현,이응봉,Lee, Ju-Hyun,Lee, Eung-Bong 한국과학기술정보연구원 과학기술정보센터 2004 Journal of Information Science Theory and Practice Vol.35 No.2

본 연구에서는 딸림자료 중 특히, 오디오 테이프 형태의 자료를 디지털화하여 멀티미디어 데이터베이스를 구축함으로써 이용자의 이용편의와 자료관리의 효율성을 제고하는 것에 대한 방안에 대해 논의하고자 한다. 이를 위해 본고에서는 딸림자료의 관리현황, 오디오 데이터 포맷의 종류, 데이터 포맷변환, 관리 및 이용방안 등을 살펴보았다. 또한, 딸림자료의 멀티미디어 데이터베이스 구축을 통한 기대효과 및 문제점을 제시하였다. This study is expected to discuss some methods regarding the uplift of user's use convenience and the efficiency of material management by constructing the multimedia database through the digitalization of the especial audiotape-typed materials among accompanying materials. In order to do that, this paper dealt with the present management conditions of accompanying materials, the sorts of audio data formats, data format transformation, the methods of administration and utilization, etc. And this paper also presented the expected effect and problems caused by multimedia databases construction of accompanying materials.

치자시탕(梔子豉湯) 투여로 호전된 만성 피부 소양증 치험 2례

이주현,조소현,조은희,박민철,Lee, Ju-Hyun,Jo, So-Hyun,Jo, Eun-Heui,Park, Min-Cheol 대한한방안이비인후피부과학회 2022 한방안이비인후피부과학회지 Vol.35 No.4

Objectives : This study is to report two cases of chronic skin pruritus improved by Chijasi-tang. Methods : Chijasi-tang was prescribed to two chronic skin pruritus patients. One patient took Chijasi-tang for 30 days and the other took it for 15 days. We compared patients' symptoms before and after treatment using self-made standards. Results : Patients who complained of pruritus on the elbow and thigh, pruritus decreased from NRS 8 to 1, and skin symptoms improved from 16 to 2. The other patient who complained of pruritus in the neck and chest, pruritus improved from NRS 9 to 2, and skin symptoms at the lesion site improved from 12 to 2. Also, accompanied symptoms such as heat of the feet and heartburn almost disappeared. Conclusions : After prescribing Chijasi-tang to two chronic skin pruritus patients, significant improvements were observed. It is thought that Chijasi-tang can be used as the treatment of other skin diseases in the future.

NDSL 웹사이트 분석 및 서비스 품질평가

이주현,이응봉,김환민,Lee, Ju-Hyun,Lee, Eung-Bong,Kim, Hwan-Min 한국과학기술정보연구원 과학기술정보센터 2006 Journal of Information Science Theory and Practice Vol.37 No.4

본 연구는 NDSL 웹사이트 전반에 대한 이용자 입장에서의 전문가 서비스 품질평가와 측정도구를 이용한 웹사이트 품질평가를 통해 문제점을 분석하고 개선방안을 제시함으로써 웹서비스의 효율성과 품질향상을 도모하고자 한다. 웹사이트 분석의 경우 NDSL 웹사이트의 완성도 분석과 사용자가 직관적으로 판단할 수 있는 이용상의 문제점을 파악하였고, 웹기반 서비스 품질평가는 데이터베이스 품질평가 항목 중 서비스 품질을 중심으로 검색성 및 사용성 평가를 진행하였다. 분석결과 전반적으로 이용에 큰 문제가 없는 것으로 나타났으나 검색 후 로딩 속도, 웹사이트 완성도, 사용자 체감, 개인정보보호, 메타데이터의 완성도, 웹사이트 접근성 등에서 여러 가지 문제점들이 발견되었다. 또한 웹사이트 서비스 품질평가 결과, 검색성 및 사용성 부분에서 검색방법과 검색결과 출력기능, 마크 리스트, Full-text 관련 항목에서 모두 만족하는 결과를 보이고 있지는 않지만 타 정보제공 기관과 비교하여 비슷한 수준의 품질을 보이고 있다. The purpose of this study is to improve the effectiveness and quality of web service by analyzing the web service problems and suggesting the solutions through the expert service quality evaluation from the point of view of users and website quality evaluation by measurement tools for a whole NDSL website. In case of website analysis, this study analyzed the website completeness of NDSL site and looked into the problem that users can judge by intuition during their use of the site, and evaluated the searchability and usability for web-based service quality evaluation by centering on the service quality of database quality items. After the results of this analysis, it appeared that there was not a big problem on the use. But after searching, several problems were found on loading rates, website completeness, user sensitiveness, the protection of private information, metadata completeness, website accessability, etc. And as a result of the evaluation of website service quality, it does not show the all satisfactory results in the function of search methods and search result printing, mark list and the items related to full-text in the part of searchability and usability. However, comparing with the results of other information organizations, it shows the similar level of quality.

소아환자에서 chloral hydrate와 hydroxyzine을 사용한 진정치료 시 생징후 평가

이주현,박호원,Lee, Ju-Hyun,Park, Ho-Won 대한소아치과학회 2002 大韓小兒齒科學會誌 Vol.29 No.3

최근 치과에 내원하는 환아의 연령이 어려지고, 장애아 및 행동조절이 어려운 환아의 치료에 관심이 높아지고 있어 이를 위한 한가지 방법으로 진정치료가 고려되고 있으며 그 중 chloral hydrate/hydroxyzine을 사용한 진정치료가 널리 오랫동안 사용되어 왔다. 이 연구에서는 강릉대학교 치과병원 소아치과에 내원하여 국소마취 하 수복치료가 필요하고, 통상의 행동조절에 반응하지 않거나 너무 어려 행동조절이 불가능한 아동을 대상으로 chloral hydrate/hydroxyzine을 사용 진정치료를 시행하고 생징후를 측정하였다. 이상의 결과 생징후는 chloral hydrate/hydroxyzine을 사용한 진정치료시 일시적 자극을 제외하고는 큰 변화를 보이지 않으며, 환아의 수면에 따른 호흡과 심박수의 감소가 관찰되었다. 따라서, 이러한 진정치료는 행동조절이 불가능하거나 아주 어린 아동에서 생징후에 영향을 적게 주면서 적절한 진정을 유도할 수 있는 방법이라 여겨진다. Currently, the ages of the patients visiting dental hospital for dental care are becoming younger and the interest in the treatment for the handicapped and incapable of cooperation children increases. As a method for treatment of these patients, the sedation treatment is considered. A dental sedation using chloral hydrate and hydroxyzine of them were used widely and for a long time. In this study, the samples were consisted of incapable of cooperation or very young children required treatment of restoration under local anesthesia. Then, the vital signs were accessed in pediatric dental sedation using the combination of chloral hydrate and hydroxyzine. As a result of this study, the vital signs were little different in pediatric dental sedation using the combination of chloral hydrate and hydroxyzine. Simply, the respiration rate and pulse rate decreased according to sleeping of patients. Therefore, the sedation using the combination of chloral hydrate and hydroxyzine induced to appropriate sedation in incapable of cooperation or very young children with little effects of vital signs.