골종양 절제후 방사선 조사한 자가골을 이용한 재건술

이종석,전대근,김석준,이수용,양현석,Lee, Jong-Seok,Jeon, Dae-Geun,Kim, Sug-Jun,Lee, Soo-Yong,Yang, Hyun-Seok 대한근골격종양학회 1997 대한골관절종양학회지 Vol.3 No.1

PURPOSE : For the reconstruction of large bone defect after tumor resection, it is possible to reuse the bone involved by tumor with some treatment to it. Several bone-reusing methods have been reported such as autoclaving, low-heat treatment(pasteurization) and intraoperative radiotherapy. We have used extracorporeally radiated autogenous bone graft for reconstruction after tumor resection, and analyzed the periods for junctional union, functional results and complications to know the indications of this method. METHODS : From Dec. 1993 to Sept. 1995, nine patients had taken autogenous bone graft with extracorporeal irradiation. Eight cases were osteosarcoma and 1 giant cell tumor. The graft sites were 5 in femur, 3 proximal tibia and 1 femur and tibia. Stage 3 was 1 case(GCT), Stage IIB 3 and Stage IIIB 5. After wide resection, surrounding soft tissue and intramedullary and extramedullary portion of the tumor were removed. Radiation was done in 5000cGy to the resected bone. Ender nails and bone cement were inserted and filled into the medulla to prevent fracture. RESULTS : Average follow-up period was 12.3(4 to 21) months. Average junctional union period in simple X-ray was 6.5 months in 4 cases. Average functional score following Enneking's criteria was 19(12-27). Complications were as follows ; condylar fractures and femur neck fracture in 4 cases, subluxation of the knee joint 3 and infection 1. Although local recurrence was detected in 1 case, the site of recurrence was not in the radiated bone but surrounding soft tissue. At final follow-up, no recurrence was found in one case(GCT), CDF 2, AWD 2, DOD 3, and died of chemotherapy related sepsis 1. CONCLUSIONS : Extracorporeally radiated bone autograft is considered to be a method for reconstruction of the large bone defect made by tumor resection, especially in the reconstruction around the joint.

ASM-IV를 이용한 부유사농도 연직분포의 측정

이종석,맹봉재,차영기,Lee, Jong-Seok,Myeng, Bong-Jae,Cha, Young-Kee 한국방재학회 2006 한국방재학회논문집 Vol.6 No.1

본 연구는 강우시 소하천 수로구간에서 유사농도의 연직분포를 유사량 측정기 (ASM-IV)로 실측하여 그 특성을 분석하고자 한다. 이를 위해 충남 연기군 서면에 위치한 월하천 시점부분의 수로구간을 연구대상으로 선정하였다. 실측된 부유사농도의 분석자료는 상하류구간에서 각각 1시간 11분 30초 및 40분 32초 동안에 2초 간격으로 측정된 2,145개 및 1,216개중 16개씩의 시간구간 자료가 사용되었다. 분석한 결과, 상류구간의 실측치 Rouse 수는 $0.00129{\sim}0.02394$로 분포하고, 평균값은 0.01129로 나타났으며, 하류구간에서는 $0.00118{\sim}0.00822$, 평균값은 0.00436으로 하류의 값이 상류의 값보다는 훨씬 작게 분포하는 것으로 나타났다. 계산치 Rouse 수는 상류구간의 경우 $0.065115{\sim}0.065295$, 평균값은 0.06521로 나타났고, 하류구간의 경우에는 $0.057315{\sim}0.059109$, 평균값은 0.05795로 하류구간이 상류구간보다 약간 작은 값을 갖으나, 실측치 비교에서의 차이보다는 적게 나타났다. 그러나 실측치와 계산치의 비교에서는 상류구간보다 하류구간에서 더 큰 차이를 갖는 것으로 나타났는데, 이 오차는 하류구간의 침강속도 산정시 높은 수온에 대한 동점성계수 값을 본 연구에서 유도한 경험식으로 계산한 것도 원인중의 하나에 포함될 것이다. This study aims to analysis of suspended-load concentration in related to those data by measuring vertical sediments distribution with rainfall using the ASM (Argus Surface Meter)- IV at the channel reach of a upstream and a downstream in small river. The watershed, small river basin where had taken for experimental study was selected, which is a drainage area lied at Walha in Yunkee-Gun, Chungnam Province. Measured data of suspended-load concentration consists of two groups with 2,145 data during 1hr 11min 30sec and 1,216 data during 40min 32sec for measuring time of 2 second in the study reaches at river, respectively. In order to analyze of the vertical concentration distribution, using the data sets are selected the measuring time 16 sets one of these data by random in the study reaches. As a results, the Rouse number of a measured and a calculated value show that a rang of $0.00129{\sim}0.02394$, averaged value of 0.01129 md, a rang of $0.00118{\sim}0.00822$, averaged value of 0.00436 in upstream reaches, and also a rang of $0.065115{\sim}0.065295$, averaged value of 0.06521, and a rang of $0.057315{\sim}0.059109$, averaged value of 0.05795 in downstream reaches, respectively. These difference show that measured Rouse number compared with downstream reach errors of less than in upstream reach, but between measured and calculated of the Rouse number compared with downstream reach errors of more than in upstream reach, respectively. It seems to will be included one of the occurrence errors of variable estimations when Rouse number of calculated value to be made computed by the fall velocity with a high temperature of water using equation of empirical kinematic viscosity was derived in this study.

충전각형강관 기둥-합성 H형강보 접합부 휨성능 결정요인에 관한 연구

이종석,Lee, Jong Seok 한국강구조학회 1999 韓國鋼構造學會 論文集 Vol.11 No.4

철골구조물에 각형강관기둥과 H형강보가 많이 사용되는 추세에 있다. 각형강관기둥과 H형강보의 접합부는 그 회전강성이 약한 것으로 알려져 있다. 그러한 약점을 보완하기 위해서 콘크리트 충전된 각형강관과 H형강보 접합부에 대한 많은 고안이 이루어지고 있다. 그런데 이렇게 고안된 모든 접합부 모델에 대해서 실험을 행할 수는 없으므로 수치해석 모델링과 수치해석에 의해 그 강도를 규명해야 한다. 본 논문에서는 유한요소 모델링기법을 연구하고 접합부의 강성을 좌우하는 여러요소 즉 콘크리트 강도, 각형강관두께, 축력의 크기 및 편심위치 등을 변화시켜 접합부 강성변화에 어떤 영향을 미치는지 살펴보았다. Square hollow section columns and H-section beams have recently been increasing1y used. Rigid column-beam connections cannot be made for the structural system and thus some measures to improve the rotational stiffness of connections should be developed. For this purpose, several types of connections. such as H-section beams connected to concrete-filled square hollow section columns, have been contrived and put to experiment. Since the experimental works are usually difficult and expensive. Particularly test of all the types of connections with similar behavior may not be feasible. Instead, the numerical analysis will be adopted predict the flexural stiffness of connections. In this work, FEM modeling techniques are examined and parametric analysis study has been carried out. The major parameters considered are concrete strength, thickness of steel column, magnitude and eccentricity of axial forces.

연부 육종의 예후 인자 - 205례 분석 -

이종석,전대근,이수용,김석준,정동환,박현수,Lee, Jong-Seok,Jeon, Dae-Geun,Lee, Soo-Yong,Kim, Sug-Jun,Jung, Dong-Whan,Park, Hyun-Soo 대한근골격종양학회 1997 대한골관절종양학회지 Vol.3 No.2

Twenty hundred and five out of 266 patients who were registered in Korea Cancer Center Hospital from Mar. 1985 to Jan. 1994, were analyzed in the aspect of survival and local recurrence. Fifty one patients were excluded due to inadequate data and follow up. Prognostic factors for survival were evaluated statistically. One hundred and four cases were male, 101 female. Average age was 39.7(range 1 to 77) year with a peak incidence around 4th decade. The most frequent diagnosis was malignant fibrous histiocytoma(MFH)(24.1%). Liposarcoma, synovial sarcoma, rhabdomyosarcoma, malignant peripheral nerve sheath tumor and fibrosarcoma were relatively common diagnostic entities, in decreasing order. In location, extremity was 179(87.3%) and trunk 26(12.7%). Average follow up period was 7.5 years(6 months to 10 years). Actuarial 5 years and 10 years survival rate were 64.0% and 40.8% respectively. In univariate analysis with log-lank test, significant differences in survival rate were noted in histopathological diagnosis, size(10 cm), stage and metastasis. Age, sex, tumor location, tumor depth and local recurrence didn't affect the survival rate. Adjuvant chemotherapy and/or radiotherapy did not affect overall survival rate, but lowered the local recurrence rate when compared with surgery only. Surgical margin did not affect the survival rate, but local recurrence rate was different according to each margin; 5.7% in more than wide; 39.5% in marginal; and 60.0% in intralesional excision. In multivariate analysis for results of univariate analysis with Cox's propotional model, metastasis was a meaningful factor for survival of soft tissue sarcoma.

횡문근육종의 치료

이종석,전대근,김석준,이수용,박현수,Lee, Jong-Seok,Jeon, Dae-Geun,Kim, Sug-Jun,Lee, Soo-Yong,Park, Hyun-Soo 대한근골격종양학회 1995 대한골관절종양학회지 Vol.1 No.2

Twenty three rhabdomyosarcoma patients who were registered in Korea Cancer Center Hospital from Mar. 1985 to Apr. 1994 were analysed in the aspect of treatment and survival. Thirteen cases were male and 10 female. Average age was 29.5 years(range 1 to 66). Locations of the tumor were as follows: 13 in lower extremity, 6 in upper extremity and 4 in trunk. According to the UICC classification, stage II b was 1 case, stage III a 4, stage III b 10, stage IV a 3 and stage IV b 5. In histological categories, embryonal rhabdomyosarcoma was 7 cases, alveolar 7, pleomorphic 7 and undetermined 2. Average follow up period was 35.3 months(1 tk 7.5 years). Ten cases were continuous disease free, 3 no evidence of disease, 3 alive with disease and 7 died of disease at final follow up. Kaplan-Meier's actuarial 5-year survival rate was 60.3% and 5-year continuous disease free survival rate was 31.4%, Surgical margin was an important factor in local tumor control. Although there was no definite statistical significance, our results suggest chemotherapy and radiation therapy have meaningful roles in reducing local recurrence and improving survival.

충적하천(沖積河川)의 수로양상(水路樣相)에 따른 유사(流砂) 및 흐름특성(特性)

이종석,이대철,배동만,차영기,Lee, Jong Seok,Lee, Dae Cheol,Pai, Dong Man,Cha, Young Kee 대한토목학회 1994 대한토목학회논문집 Vol.14 No.5

This paper aims to develop the numerical model for prediction of the channel migration by analyzing of sediment and flow characteristics with patterns of channel in alluvial rivers. Flow in rivers constitutes to be the meandering or the braided form and rarely straight channel through morphologically stable patterns with mutual actions between the flowing water and bed materials. In order to develop the model for simulation of the channel migration, the channels are divided into two types with positive or negative sign by the direction of curvature radius of the centerline channel ($r_c$). That is, the single bend-channel consists of only one curvature of positive or negative sign and the multi-bend channel consists of two more curvatures of positive or negative sign, respectively. The model analyzes the sediment and flow characteristics under the influence of superelevation, spiral motion, irregularity in bed topography and depth-averaged velocity of channels. For reliability of this model, the single bend-channel and the multi bend channel are compared with experiment data in other models and the measured field data in the Keum-River, respectively. As a result, the both com parisians turn out to be excellent. 본 논문은 충적하천에서 수로의 양상조건에 따른 유사 및 흐름특성을 해석함으로써 수로의 변이를 예측할 수 있는 수치모형을 개발하기 위한 연구이다. 하천의 흐름은 하상 및 제방재료 특성과의 상호작용에 의해 복잡한 관계를 이루면서 수로변이를 통하여 형태학적으로 안정적인 형상을 유지하고 흐르기 때문에 대부분의 경우 직선형수로는 드물고 사행 또는 망류상을 이루고 있다. 본 연구에서는 수로변이를 모의할 수 있는 모형을 개발하기 위해 수로중심선 곡률반경 $r_c$값의 양과 음의 부호수에 따라 수로를 구분 즉, $r_c$의 양 또는 음의 값이 하나 만으로 이루어진 단만곡수로(single-bend channel)와 양과 음이 둘 이상의 값을 갖는 복만곡수로(multi-bend channel)로 구분하여 이들 수로에서의 편수위상승, 나선운동, 하상 및 수심평균유속의 불규칙 현상의 영향에 의한 유사이동과 흐름특성을 해석한다. 단만곡수로는 타 _모형의 실험자료와 복만곡수로는 금강의 매포수위관측소를 시점으로하는 연구구간에서 실측치 현장자료와 비교분석함으로써 본 모형의 적용성을 검증하였으며, 그 결과는 대체로 잘 일치하는 것으로 나타났다.

회원마당-교회와 호스피스 봉사

이종석,Lee, Jong-Seok 한국호스피스협회 2003 한국호스피스협회 Vol.66 No.-

약침용(藥鍼用) 봉독액(蜂毒液)의 국소독성시험(局所毒性試驗)에 관(關)한 연구(硏究)

이종석,고형균,김창환,Lee, Jong-Seok,Koh, Hyung-Kyun,Kim, Chang-Hwan 대한한의학회 1995 대한한의학회지 Vol.16 No.1

Pursuant to the Medical Product Safety Administration Guidelines for safety assessment of Korean bee vonom for herb-acupuncture, rabbits were used for skin, eye balls, subcutaneous and muscle irritation test. The results were as follows; 1. The skin irritation test of bee venom for herb-acupuncture did not produce any irritation reactions, when the skin was covered with bee venom. 2. The eye irritation test produced moderate to severe stimulating reactions, once the eye mucous membrane was contacted with bee venom. 3. The subcutaneous and muscle irritation test of bee venom showed such local inflammatory reactions as death of cells, infiltration of inflamed cells, dropsical swelling, and congestion, once injected under the skin and in the muscle. As the results of the study on bee venom for herb-acupuncture indicate that severe reactions in such tests as eye balls, subcutancous and muscle irritation exist in the laboratory, more professional caution should be taken in clinical application of the therapy. In addition, further study on subacute, chronic toxicity and allergy reactions should be pursued.

연구발표초록 ( 재료 ) : 세멘트화 제법에 따른 제화용 접착제에 관한 연구

이종석,한상덕,이상신 ( Jong Seok Lee,Sang Duck Han,Sang Sin Lee ) 한국화학공학회 1992 춘계학술발표회 Vol.- No.-

온수양생을 이용한 초고강도 콘크리트의 강도 조기 추정에 관한 실험적 연구

이종석,명로언,공민호,백민수,이영도,정상진,Lee, Jong-Seok,Myung, Ro-Oun,Gong, Min-Ho,Paik, Min-Su,Lee, Young-Do,Jung, Sang-Jin 대한건축학회 2011 대한건축학회논문집 Vol.27 No.5

In this study, prediction of later-age compressive strength of ultra-high strength concrete, based on the accelerated strength of concrete cured in hot water was investigated. Comparing other acceleration method, hot water curing method is relatively easy and intuitive to use in the real construction site. The amount of time for evaluation of the concrete strength using the hot water curing method in KS and JIS is too long to predict the strength of the ultra-high strength concrete that are used in the tall building structure. For that reason, curing temperature of 40, 50, $60^{\circ}C$ 3 levels were examined to shorten the amount of time for the evaluation of the strength. When curing in warm water, different strength characteristics are verified from the experiment. In case of F3 substituting 30% fly ash in combination, because of the curing temperature sensitivity of fly ash, differences of strength expression velocity was verified according to the curing temperature at the same age. In case of B4 substituting 40% ground granulated blast furnace slag, there were no big strength expression velocity differences of the specimen cured in 3 different level of curing temperature(40, 50, $60^{\circ}C$). The results show reliable accuracy by regression relation between 28day strength cured by standard curing method and accelerated strength of concrete cured in warm water.(y=1x-0.0002 $R^2$=0.9866) As a result, the feasibility of 3day-prediction was confirmed using warm water curing method with accelerated strength of concrete cured for three days in warm water.