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      • KCI등재

        압박고나사를 이용한 대퇴골 전자하부 분쇄 골절의 치료

        이병일,최형석,나수균,김연일,임석범,서유성 대한골절학회 2001 대한골절학회지 Vol.14 No.2

        Purpose: This study was performed to analyze the weight-bearing ambulation time, bony union time and complications after fixation of comminuted subtrochanteric fractures of the femur with compression hip screw and evaluate its effectiveness. Material & Methods: From January 1993 to January 2000, 21 cases of Seinsheimer's Type IV and Type V comminuted subtrochanteric fractures of femur which were treated by compression hip screw and followed for more than 1 year were analyzed by weight-bearing ambulation time, bony union time and complications. Results: We recommended partial weight bearing ambulation from 6 weeks after operation and full weight bearing ambulation from 12 weeks after operation. All of 21 cases, primary bony union was achieved and mean time was 16 weeks(range 13 to 25 weeks). 2 cases of mechanical complications were occurred. Also 4 cases of malunion of lesser trochanter and 2 cases of nonunion of lesser trochanter were occurred, but none of them result in limitation of motion, limping nor pain. Conclusions: We thought compression hip screw is a good implant for rigid fixation of comminuted subtrochanteric fractures, especially involve intertrochanteric region like Seinsheimer's Type IV and Type V.

      • 기상성적을 이용한 미나리 생체중 예측

        이병일 서울대학교 농업개발연구소 2001 농업생명과학연구 Vol.5 No.-

        Accurate prediction of vegetable growth will help the growers in planning of cultivation and production under protected facilities. To predict the yield of water dropwort (Oenanthe stolonifera DC.) diurnally, model was developed for predicting fresh weight (FW) based on daily photosynthetic photon flux density (PPFD) and average daily temperature (ADT). Various growth parameters were examined to ascertain the allometric relationships with the FW. Dry weight and leaf area index (KAI) up to linear-growth phase had good linear relationships with FW, each showing determination coefficients of greater than 0.96. The maximum radiation use efficiency (maximum RUE, α_max) was found to be 0.0385 ㎏·mol^-1 for the FW of water dropwort. RUE followed beta distribution function in terms of ADT , (α_ADT=α_max[(39.0-ADT)/15.0][(ADT-7.5)/16.5]^(15.0/16.5)) Minimum, optimum, and maximum temperatures for RUE were estimated as 7.5, 24.0, and 39.0℃, respectively. Therefore, FW was predicted well with the function of FW=0.0385∑[α_ADT(1-e^-KLAI)PPFD].

      • KCI등재

        게이트 심근 SPECT 분석 소프트웨어의 개발과 좌심실 수축 기능 평가

        이병일,이동수,이재성,정준기,이명철,최흥국 대한핵의학회 2003 핵의학 분자영상 Vol.37 No.2

        목적 : 게이트 심근 SPECT 영상 데이터에서 좌심실을 분할하고 단위영상 각각의 심실부피를 계산하는 소프트웨어를 개발하였다. 개발한 소프트웨어에서 얻은 구혈률을 상용 소프트웨어QGS (Quantitative Gated SPECT)에서 산출한 값과 비교하여 검증하였다. 대상 및 방법 : 게이트 심근 SPECT를 시행하여 구혈률 15%-80%, 확장기말 부피는 46 mL-293 mL, 수축기말 부피는 8 mL-250 mL인 40명의 영상데이터를 사용하여 이 연구에서 개발한 CSA (Cardiac SPECT Analyzer)로 구혈률과 부피를 산출하여 QGS로 얻은 결과와 비교하였다. 같은 영상을 CSA로 두 번 분석하여 구혈률과 부피가 같은 값이 나오는지 보고, 26명의 환자에서 같은 자리에서 두 번 이어서 얻은 게이트 SPECT 영상을 CSA로 분석하여 편차를 조사하였다. 결과 : CSA 측정과 QGS측정의 상관성은 상관계수가 구혈률, 확장기만 부피, 수축기말 부피 각각 0.97, 0.92, 0.96이었고 Bland Altman 도표에 치우침 없이 2표준편차가 구혈률의 경우 10.1%이었다. 같은 영상에 대한 CSA 2회 측정 결과의 상관은 0.96, 0.99, 0.99 이었고 구혈률의 2표준편차는 3.4%이었다. 두 번 연속 촬영한 영상으로 CSA 분석한 결과 상관계수는 0.89, 0.97, 0.98, 이었고 변이계수는 8.2%, 5.4mL, 8.5mL, Bland Altman 도표 2표준편차는 구혈률의 경우 10.6%이었다. 결론: 게이트 심근 SPECT에서 얻은 영상으로 구혈률을 측정할 수 있는 소프트웨어를 개발하였다. 이 소프트웨어로 얻은 구혈률, 확장기말 부피, 수축기말 부피는 정확하며 정밀하였다. 구혈률의 2표준편차는 10.6%이었다. Objectives : A new software (cardiac SPECT Analyzer CSA) was developed for quantification of volumes and ejection fraction on gated myocardial SPECT. Volumes and ejection fraction by CSA were validated by comparing with those quantified by Quantitative Gated SPECT (QGS) software. Materials and Methods: Gated myocardial SPECT was performed in 40 patients with ejection fraction from 15% to 85%. In 26 patients, gated myocardial SPECT was acquired again with the patients in situ. A cylinder model was used to eliminate noise semi-automatically and profile data was extracted using Gaussian fitting after smoothing. The boundary points of endo- and epicardium were found using an iterative learning algorithm. Enddiastolic (EDV) and endsystolic volumes (ESV) and ejection fraction (EF) were calculated. These values were compared with those calculated by QGS and the same gated SPECT data was repeatedly quantified by CSA and variation of the values on sequential measurements of the same patients on the repeated acquisition. Results: From the 40 patient data, EF, EDV and ESV by CSA were correlated with those by QGS with the correlation coefficients of 0.97, 0.92, 0.96. Two standard deviation (SD) of EF on Bland Altman plot was 10.1%. Repeated measurements of EF, EDV, and ESV by CSA were correlated with each other with the coefficients of 0.96, 0.99, and 0.99 for EF, EDV and ESV respectively. On repeated acquisition, reproducibility was also excellent with correlation coefficients of 0.89, 0.97, 0.98, and coefficient of variation of 8.2%, 5.4mL, 8.5mL and 2SD of 10.6%, 21.2mL, and 16.4mL on Bland Altman plot for EF, EDV and ESV. Conclusion: We developed the software of CSA for quantification of volumes and ejection fraction on gated myocardial SPECT. Volumes and ejection fraction quantified using this software was found valid for its correctness and precision.

      • KCI등재

        자발성 슬관절 골괴사증의 임상적 고찰

        이병일,최창욱,나수균,최민기 대한슬관절학회 1994 대한슬관절학회지 Vol.6 No.1

        Spontaneous osteonecrosis of the knee was first described in 1986 by Ahlback et al, as a painful radiolucent lesion associated with a focally active bone scan involving the medial femoral condyle, but without any of such well known predisposing factors as oral steroids, lupus erythematosus, hyperlipidemia, alcohol, or Caisson's disease. The etiology of the lesion is still unknown and this entity is believed to be an important but uaderestimated cause of osteoarthritis of the knee. The clinical course and the prognosis of the disease depend on the radiographic size, the area, and the stage of the lesion. Bone scan allows and early diagnosis, and MRI is useful in the evaluation of separated asteonecrosis of the knee and the determination of the prognosis. Prognosis is unfavorable if the lesion is larger than five square centimeters and if its width is more than 40 % of that of the condyle. Arthroscopy not only allows an effective method of evaluating the articular lesion, but also provides an effective treatment. When varus deformity is present, the arthroscopic treatment can be associated with a high tibial osteotomy. During the period of 4 years from February, 1989 to July, 1993, spontaneous osteonecrosis was diagnosed in 15 knees in 13 patients. Of the 6 knees followed up after conservative treatment, 83 % were satisfactory. Of the 6 knees treated by arthroscopic debridement, 83 % were satisfactory, and of the 3 knees treated by osteotomy, all were satisfactory.

      • 전방십자인대 재건술 - 잔류조직 보존술식 -

        이병일,천동일,Lee, Byung-Ill,Chun, Dong-Il 대한관절경학회 2009 대한관절경학회지 Vol.13 No.2

        Optimal treatment of the torn anterior cruciate ligament (ACL) remains controversial. The complexity of surgically reproducing the natural biomechanical and anatomical function of the ACL has led to a diversity of reconstructive procedures. Controversy continues to exist regarding the best reconstructive procedure for the ACL deficient knee, but currently, there is no ideal method. Because of the increased frequency of ACL injury and the functional impairment resulting from that, the role of mechanoreceptors in the ACL recently has attracted considerable attention. Proper reconstruction of the ruptured ACL does not always have good results. Success after operation may depend not only on the mechanical stability but also on the quality of recovery of proprioception. It is well known that most ACL are ruptured in proximal half and most mechanoreceptors have been reported to be located in the subsynovial layer and near the tibial insertion of the ACL. Expected roles of tibial remnant is to enhance the revascularization and cellular proliferation of the graft, to preserve proprioceptive function, and to be able to acquire anatomical placement of the graft without roof impingement. The remnant of the ruptured ACL has been removed to clearly visualize the ACL footprint or decrease the risk of impingement and Cyclops lesion in most current techniques for ACL reconstruction. Therefore it seems reasonable to assume that preserving the tibial remnant as much as possible as a source of reinnervation, if technically possible without causing impingement, would be of potential benefit to the patient. In addition, it will facilitate the vascular ingrowth and ligamentization of the grafted ACL.

      • N-functionalization of pentaazapropellane

        이병일,김남태,오정환,김진석,김영규 한국공업화학회 2015 한국공업화학회 연구논문 초록집 Vol.2015 No.0

        Explosive performances of energetic materials are influenced by their molecular structure, heats of formation, and the N/O/C balance in the molecules. Hexanitrohexaazaisowurtzitane (HNIW) is one of the most powerful high explosives in commercially available known to date. Azapropellanes with a high N/O content are rather strained but easier to synthesize. Some nitroazapropellanes with the N-NO2 groups have been calculated to release higher detonation power than well-known RDX or HMX. We have recently published the synthesis of several novel pentaaza[3.3.3]propellanes and their N-nitro derivatives. In this presentation, we will report the N-functionalization study of some pentaaza[3.3.3]propellanes and their characterization results.

      • KCI등재

        게이트 심근 SPECT를 이용한 좌심실의 국소탄성률 평가방법 개발 및 재현성 평가

        이병일,이동수,이재성,강원준,정준기,이명철,최흥국 대한핵의학회 2003 핵의학 분자영상 Vol.37 No.6

        목적: 게이트 심근 SPECT 영상에서 국소부피변화를 얻으면, 요골동맥 긴장도를 측정하여 얻은 중심 동맥의 압력 곡선으로부터 최대탄성률을 얻을 수 있다. 이 연구에서는 좌심실의 국소탄성률을 평가하기 위한 방법을 개발하고 국소탄성률 측정의 재현성을 평가하였다. 대상 및 방법: 게이트 Tc-99m MIBI 심근 관류 SPECT를 두 번 연속으로 시행한 환자 7명(남:여=5:2, 58±11.9세)을 대상으로 하였다. 국소적 부피변화를 측정하기 위하여 개발한 CSA(Cardiac SPECT Analyzer) 소프트웨어를 이용하여 좌심실의 부피변화를 측정하였으며, 시간-압력 곡선과 국소 시간-부피 곡선을 이용하여 반복연산을 통하여 구한 국소 시간-탄성율 곡선에서 국소탄성률을 얻었다. 같은 SPECT 영상에 대해서 두 번 측정한 국소탄성률의 재현성과, 같은 환자에서 연속하여 두 번 얻은 SPECT 영상에 대해서 측정한 국소탄성률의 재현성을 평가하였다. 결과: 평균 국소탄성률은 15분할모델에서 3.36±3.38 mmHg/mL이었으며, 7분할모델과 5분할모델에서 각각 3.16±2.25 mmHg/mL, 3.11±2.57 mmHg/mL이었다. 국소탄성률의 조화평균은 전체탄성률과 일치하였다. 동일한 데이터에서 두 번 측정한 국소탄성률 값의 상관계수는 모든 모델에서 0.97이상이었고, Bland Altman 도표에서 차이의 2-표준편차는 각각 1.5%, 1.0%, 0.9%였다. 동일 환자에서 두 번 연속 촬영한 SPECT 데이터로부터 측정한 국소탄성률의 상관계수는 모든 모델에서 0.95이상이었으며, Bland Altman 도표에서 차이의 2-표준편차는 각각 2.2%, 1.0%, 1.2%였다. 결론: 게이트 심근 SPECT를 이용한 좌심실의 국소탄성률을 측정하였으며 재현성 있는 결과를 얻었다. 심근 SPECT를 이용하여 얻은 국소탄성률의 평가방법은 향후 임상적인 데이터를 바탕으로 새로운 심기능 분석지표로 활용될 수 있을 것이다. Purpose: Regional contractility can be calculated using the regional volume change of left ventricle measured by gated myocardial SPECT image and curve of central artery pressure obtained from radial artery pressure data. In this study, a program to obtain the regional contractility was developed, and reproducibility of regional contractility measurement was assessed. Materials and Methods: Seven patients )male:female=5:2, 58±11.9 years) with coronary artery diseases underwent gated Tc-99m MIBI myocardial SPECT twice without delay between two scans. Regional volume change of left ventricle was estimated using CSA (Cardiac SPECT Analyzer) software developed in this study. Regional contractility was iteratively estimated from the time-elastance curve obtained using the time-pressure curve and regional time-volume curve. Reproducibility of regional contractility measurement assessed by comparing the contractility values measured twice from the same SPECT data and by comparing those measured from the pair of SPECT data obtained from a same patient. Results: Measured regional contractility was 3.36±3.38 mmHg/mL using 15-segment model, 3.16±2.25 mmHg/mL using 7-segment model, and 3.11±2.57 mmHg/mL using 5-segment model. The harmonic average of regional contractility value was almost identical to the global contractility. Correlation coefficient of regional contractility values measured twice from the same data was greater than 0.97 for all models, and two standard deviations of contractility difference on Bland Altman plot were 1.5%, 1.0%, and 0.9% for 15-, 7-, and 5-segment models, respectively. Correlation coefficient of regional contractility values measured from the pair of SPECT data obtained from a same patient was greater than 0.95 for all models, and two standard deviations on Bland Altman plot were 2.2%, 1.0%, and 1.2%. Conclusion: Regional contractility of left ventricle measured using developed software in this study was reproducible. Regional contractility of left ventricle will be a new useful index for myocardial function after analysis of the clinical data.

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