Distribution of Disease Severity and Group A Rotavirus Genotypes (VP7 & VP4) in Children with Acute Rotavirus Gastroenteritis

오현주,강현식,강기수,김연우,홍정연,신경수,이진숙,이수현,이근화,조문제,서동인,Oh, Hyun-Ju,Kang, Hyun-Sik,Kang, Ki-Soo,Kim, Youn-Woo,Hong, Jung-Yun,Shin, Kyung-Sue,Lee, Jin-Sook,Lee, Su-Hyun,Lee, Keun-Hwa,Cho, Moon-Je,Suh, Dong-In The Korean Society of Pediatric Gastroenterology 2011 Pediatric gastroenterology, hepatology & nutrition Vol.14 No.2

목적: 저자들은 지역사회에서, 로타바이러스 장염에 걸린 소아들에서 질환의 중증도와 로타바이러스 VP7 유전형과 VP4 유전형의 분포에 대해 알아보고자 하였다. 방법: 2007년 12월부터 2008년 6월까지 로타바이러스 장염으로 병원에 입원한 156명의 소아들에서 대변 샘플을 수집하였다. 모든 환자들에 대한 질환 중증도는 Vesikari 점수를 이용하여 평가하였다. 로타바이러스 ds-RNA를 분리한 후, 역전사 중합효소 연쇄반응과 다중 중합효소 연쇄반응을 이용하여 cDNA를 합성하였다. 마지막으로 유전형을 확인하였다. 결과: 156명의 환자 샘플에서, VP7(G)는 147명(94.2%)에서 확인되었고 VP4(P)는 140명(89.7%)에서 확인되었다. G1 유전형(147명 중 116명; 78.9%)과 P[8] 유전형(140명 중 137명)이 각각 가장 많았다. VP7과 VP4 조합형은 138명에서 확인할 수 있었는데, G1P[8] 조합형이 111명(80.4)으로 가장 많았다. 다른 조합형들은 종류가 다양하였고 분포가 낮았다. 전체 조합형 중 9.4%가 새로운 로타바이러스 백신에 포함되지 않은 것이었다. 로타바이러스 장염의 질환 중중도는 $11.8{\pm}3.3$ ($mean{\pm}2SD$)였다. 전체 환자에서 경증 내지 중등도가 37.8%였고, 중증은 62.2%였다. 결론: 로타바이러스 유전자 조합형 중 가장 흔한 것은 G1P[8]이었다. 새로운 백신에 포함되지 않은 유전자 조합형은 9.4%였다. 로타바이러스 장염으로 입원한 소아들의 질환 중증도분포는 경증과 중등도보다 중증에서 높게 나타났다. Purpose: We aimed to study the distribution of rotavirus genotypes (VP7 and VP4) and disease severity of rotavirus gastroenteritis prevalent in our community. Methods: Stool samples were collected from 156 children who were hospitalized with rotavirus gastroenteritis from December 2007 to June 2008. The disease severity of all patients was scored using the Vesikari scale. After extraction of ds-RNA of the rotavirus, cDNA synthesis using reverse transcription and polymerase chain reaction (RT-PCR) and multiplex PCR was performed. Following this, the final identification of genotypes was performed. Results: Of the 156 samples, VP7(G) and VP4(P) genotypes were identified in 147 (94.2%) and 140 (89.7%) samples, respectively. G1 (116 of 147 samples; 78.9%) and P[8] (137 of 140 samples; 97.9%) were the most prevalent, respectively. Of the 138 samples identified of combination types of VP7 and VP4, G1P[8] (111 samples; 80.4%) was the most prevalent. Other combination types varied with very low distribution rates. 9.4% of genotypes were not included in the new vaccines. The disease severity score was $11.8{\pm}3.3$ ($mean{\pm}2SD$). The distribution of disease severity was mild or moderate in 37.8% and severe in 62.2% of patients. Conclusion: The most prevalent genotype combination of rotavirus was G1P[8] and genotypes not included in the vaccines represented 9.4% in our community. Disease severity distribution of hospitalized children with rotavirus gastroenteritis was higher in the severe than in the mild and moderate categories.

Salmonella enteritidis 위장관염에 합병된 급성 비결석성 담낭염 1예

오현주,강현식,강기수,김승형,김봉수,김광식,Oh, Hyun-Ju,Kang, Hyun-Sik,Kang, Ki-Soo,Kim, Seung-Hyung,Kim, Bong-Soo,Kim, Kwang-Sig 대한소아소화기영양학회 2009 Pediatric gastroenterology, hepatology & nutrition Vol.12 No.1

저자들은 평소 건강하던 9세 남아에게서 Salmonella enteritidis 위장관염에 합병된 급성 비결석성 담낭염을 임상증상, 혈액 검사 및 배양 검사, 복부 초음파 검사등을 통하여 진단 할 수 있었다. 또한 항생제 치료와 비수술적 방법인 경피경간 담낭배액술을 통하여 성공적으로 치료 하였기에 이에 보고하는 바이다. We report a rare case of acute acalculous cholecystitis (ACC) caused by Salmonella enteritidis infection in a previously healthy 9-year-old boy. Salmonella enteritidis was isolated from stool and bile culture. The diagnosis of ACC was established upon clinical, laboratory, and ultrasonographic findings. The patient was successfully treated using percutaneous transhepaticcholecystic drainage (PTCCD) in combination with antibiotics therapy.

PNF 목 패턴이 전방머리자세를 가진 성인의 목 움직임 및 목 장애 지수에 미치는 영향

오현주,송귀빈,Oh, Hyun-Ju,Song, Gui-Bin 대한고유수용성신경근촉진법학회 2016 PNF and Movement Vol.14 No.3

Purpose: The purpose of this study was to investigate the effects of neck patterns in proprioceptive neuromuscular facilitation (PNF) for neck movement and the neck disability index (NDI) among adults with forward head posture. Methods: Thirty-nine subjects were randomly assigned into two groups. Subjects in the proprioceptive neuromuscular facilitation exercise group (PNFG, n = 20) received 20 minutes of PNF neck pattern (flexion-Rt. lateral flexion-Rt. rotation followed by extension-Lt. lateral flexion-Lt. rotation) 3 times weekly for 4 weeks. Outcomes were measured using absolute rotation angle (ARA), anterior weight bearing (AWB), range of flexion and extension motions (RFEM), and neck disability index (NDI) methods before and after the 4-week intervention period. Results: There were significant effects for the PNFG, pre- and post-intervention, in ARA, AWB, RFEM, and NDI. There were significant differences in ARA, AWB, RFEM, and NDI compared with CG. Conclusion: The results of this study suggest the PNF neck pattern could be beneficial for adults with forward head posture.

한국표준질병사인분류의 개정에 관하여

오현주,OH, Hyun-Ju 한국생명보험의학회 2008 保險醫學會誌 Vol.27 No.1

The 5th revision of Korean Classification of Diseases(KCD) became effective on January 1, 2008. It has reflected the changes made to the tenth revision of International Classification of Diseases (ICD-10) between 1998 and 2005 and the suggestions of academic and related societies in Korea. Two important alterations seem to have a major implication in the insurance industry. One would be the official introduction of a Korean version of International Classification of Diseases for Oncology, third edition(ICD-O-3). The borderline ovarian tumor is classified as a borderline neoplasm, which was classified as a malignant neoplasm in the previous edition of International Classification of Diseases for Oncology. The other would be the appearance of non-C-code malignant neoplasm for the diseases, such as polycythemia vera, newly classified as a malignant neoplasm by the current edition of International Classification of Diseases for Oncology. The National Office of Statistics(NSO) adopted the way of implementation used in the Australian Modification of International Classification of Diseases(ICD-10-AM), instead of assigning them into corresponding C code. Overall, the changes made in this revision doesn't seem to have a serious impact on the insurance industry since it has only reflected updates made to ICD-10.

만성중심장액맥락망막병증에서 절반 에너지보다 낮은 에너지를 이용한 광역학치료의 효과

오현주,장우혁,사공민,Hyun Ju Oh,MD,Woohyok Chang,MD,PhD,Min Sagong,MD,PhD 대한안과학회 2013 대한안과학회지 Vol.54 No.7

Purpose: To investigate the safe, effective light dose for photodynamic therapy (PDT) in the treatment of chronic central serous chorioretinopathy (CSC). Methods: Thirty-eight eyes of 37 patients with chronic CSC were recruited for this study. From November 2009 to July 2010 and from April 2011 to February 2012, PDT was performed using 50% and 25% of the full light dose in 27 eyes of 27 patients (group I) and 11 eyes of 10 patients (group II), respectively. The minimum follow-up period was 6 months. Mean change in best corrected visual acuity (BCVA) and central retinal thickness, hyperpermeability change from abnormal choriocapillaris, success rate, recurrence rate, and complications were analyzed. Results: Group I showed that BCVA (log MAR) improved significantly from 0.33 ± 0.17 to 0.14 ± 0.15 at 6 months (p < 0.001). However, there was no significant improvement of BCVA (p = 0.050) in group II. One eye out of 27 eyes (3.7%) in group I and 5 eyes out of 11 eyes (45.5%) in group II showed recurrence at the 6-month follow-up (p = 0.016). After initial PDT, hyperpermeability from abnormal choriocapillaris reduced or disappeared at 95.5% in group I and 54.5% in group II at month 3 (p = 0.016). No patient in either group experienced severe adverse events. Conclusions: PDT performed with 50% of the full light dose appears to be a more useful method in the treatment of chronic CSC, with less frequent recurrence, than PDT using 25% of the full light dose.

굴곡-신연기법과 낙차 교정법이 허리 척추사이원반 탈출증 환자의 시각적 상사 척도 및 엉치뼈 각에 미치는 영향

오현주,최석주,이관섭,최지운,Oh, Hyun-Ju,Choi, Seok-Joo,Lee, Kwan-Sub,Choi, Ji-Oun 대한물리치료과학회 2018 대한물리치료과학회지 Vol.25 No.3

Background: In order to find out the effect of therapy methods through Flexion-distraction technique and drop technique on pain, sacral angle of patients with lumbar herniated intervertebral disc targeting patients with lumbar herniated intervertebral disc due to L5-S1. Method: This study was to present the directivity of the therapy method for lumbar herniated intervertebral disc by comparing and analyzing the spinal decompression therapy and provide an effective treatment method to patients with lumbar herniated intervertebral disc by identifying the therapeutic effect of Flexion-distraction technique and drop technique. The research period is March 1, 2018 to June 30, 2018 and subjects are the patients diagnosed as lumbar herniated intervertebral disc due to L5-S1 by their doctor through clinical findings and medical equipment such as X-ray, CT, MRI etc. Among patients who visited and hospitalized in S Orthopaedics located in Daegu and 30 female patients with sacral angle of more than $30^{\circ}$ were randomly classified into 15 people and we carried out treatment three times a week for 8 weeks for 15 people in the experimental group applying Flexion-distraction technique and drop technique and 15 people in the control group applying spinal decompression therapy to compare and analyze the changes in pain, sacral angle of patients with lumbar herniated intervertebral disc. Result: According to the results of this study, changes in the Visual Analogue Scale showed statistically significant differences in both the experimental group and control group(p<.05), while there was statistically significant difference in the comparison between groups before and after measurement of experimental group (p<.05). In the comparison within two groups of sacral angle, both groups showed statistically significant difference(p<.05) but there was no statistically significant difference in the comparison of scores between groups before and after measurement of each group(p>.05). Discussion: All those results the above proved that we need to confirm various benefits of the therapy with the flexion-distraction technique and drop technique, and the findings of the concerned study will possibly become useful information when doctors actually work on a therapy to treat patients with the lumbar herniated intervertebral disc.

듀안안구후퇴증후군의 얼굴돌림과 내전시 과도한 상하전에 대한 수술적 치료

오현주,문성혁,김명미,Oh Hyun Ju,Sung Hyuk Moon,Myung Mi Kim 대한안과학회 2013 대한안과학회지 Vol.54 No.6

Purpose: To present the results of patients undergoing surgical treatment and determine clinical guidelines for the face turn, and up and down shoot in Duane retraction syndrome (DRS). Methods: Thirty-four patients with DRS were treated with single horizontal rectus muscle recession, lateral rectus (LR) recession with Y-splitting, or LR recession with Y-splitting combined with medial rectus (MR) recession. The different treatment approaches were based on the angle of deviation in the primary position, versions, and ductions. In all patients, ocular alignment, face turn and up and down shoot were assessed preoperatively and postoperatively. Results: The average standard deviation reduced from 18.5 ± 6.5 prism diopters (PD) to 4.6 ± 5.8 PD in horizontal rectus muscle recession and 14.4 ± 5.5 PD to 1.6 ± 2.8 PD in LR recession with Y-splitting. LR recession with Y-splitting combined with MR recession was effective in reducing globe retraction. Postoperative 4-mm LR recession with Y-splitting did not change ocular alignment; 7-mm LR recession with Y-splitting showed an average correction of 12.8 PD. Postoperatively, all patients presented a reduction in face turn; however, there was no statistically significant difference between the 2 procedures (Mann-Whitney U test, p = 0.620). Conclusions: Decisions regarding surgical approaches in DRS should be based on the amount of deviation in primary eye position, the expression of up and down shoot, and the degree of face turn. Surgeons planning Y-splitting of LR with MR recession must consider modifying the MR recession amount due to the smaller LR recession effect of Y-splitting compared with conventional LR recession.

라이선스 뮤지컬의 로컬화 방식에 대한 사례 연구

오현주 ( Hyun Ju Oh ),김영찬 ( Young Chan Kim ) 한국커뮤니케이션학회 2014 커뮤니케이션학연구 Vol.22 No.4

본 논문은 대중문화 산업에서 나라간 경계를 넘는 교류와 수용이 이루어지는 경향 안에서 한국에서 공연되는 라이선스 뮤지컬 중 한국의 지역적 특성과 수용자를 고려하는 맥락화 과정을허용하고 있다는 점에 주목하였다. 그리고 이 과정을 거쳐 재탄생된 라이선스 뮤지컬은 새로운형식의 문화 텍스트로서 그 의미를 지니게 되었음을 살펴보고자 한다. 이에 한국에서 공연되는동안 원작을 비하여 무대와 캐릭터 등에 변화를 줌으로써 전혀 새로운 텍스트로서 선보이게 되는 라이선스 뮤지컬을 통해 현재 한국 뮤지컬 산업에서 라이선스 공연의 도입이 어떠한 함의를지니고 있는지를 알아보고자 한다. 그리고 한국에서 라이선스 뮤지컬이 수용되고 있는 흐름은비단 이 영역뿐 아니라 텔레비전을 비롯한 대중문화 전반적인 영역에서 일어나는 다양한 현상과 연결된 것으로 총체적인 관점을 적용할 수 있다. 라이선스 뮤지컬이라는 틀 안에서 한국의지배적인 문화적 정체성은 어떻게 재현되고 있는지, 그 안에서 탄생한 캐릭터와 이미지가 만들어내는 담론들로 덧씌워진 텍스트로서의 K-musical에 대해 재정의 하고자 한다. This paper looks into the specific ways in which European musicals areappropriated to meet the cultural tastes of Korean audiences as well as theproduction environments of Korean musical industry. This work attempts to find outhow licensed productions that are drastically reconfigured in the local keeptransforming themselves and eventually contribute to the making of ’K-Musical’. Through a case study and symptomatic reading of <Jack, the Ripper> and a coupleof other licensed productions in Korean musical market, this research shows how itslicensed version in Korea richly implicates cultural sensibilities and industrialcontexts of the local and therefore seriously calls into question the easy binaryopposition of ‘global culture, local consumption’. Furthermore, studying K-Musicalalso requires us to pay close attention to other central domains in Korean popularculture -television and popular music. Popularization and success of K-Musical isclosely intertwined with the casting of K-Pop ‘idol stars’ whose members are nowliterally enjoying ‘global fandom’. In this sense, K-Musical is a multifaceted culturalphenomenon that begs immediate understanding and interpretation.

신장 : 급성 신부전을 동반한 부동화에 의한 고칼슘혈증성 신증 1예

오현주 ( Hyun Ju Oh ),박지수 ( Ji Soo Park ),김조은 ( Jo Eun Kim ),윤해리 ( Ha Rry Yoon ),김지수 ( Ji Soo Kim ),김효영 ( Heo Young Kim ),김형종 ( Hyung Jong Kim ) 대한내과학회 2012 대한내과학회지 Vol.82 No.6

본 증례는 부동화가 지속되는 상태의 환자에서 발생한 고칼슘혈증과 관련되어 급성신부전이 발생한 경우로, 드물기는 하지만 고칼슘혈증과 관련되어 급성 신부전이 발생할 수 있으며 글루코코르티코이드의 사용이 고칼슘혈증 및 급성신부전 호전에 도움이 될 수 있을 것이라 생각된다. Hypercalcemia commonly occurs because of primary hyperparathyroidism and metastatic malignancies, such as multiple myeloma, breast cancer and lung cancer; these causes account for 90% of cases. The other causes of hypercalcemia are numerous, and immobilization is an under-appreciated etiology. The mechanisms underlying immobilization-induced hypercalcemia are uncertain. However, an overall increased osteoclastic bone resorption and decreased osteoblastic bone formation can induce hypercalciuria and hypercalcemia. Additionally, hypercalcemia can induce and be associated with acute kidney injury, but it is rarely reported in immobilization hypercalcemia. We report here a 58-year-old man with suspected immobilization hypercalcemia associated with acute kidney injury and treated successfully with glucocorticoids.

현대중국어 客套语 교육 현황 고찰

오현주(Oh, Hyun-Ju)(吳昡,妵,) 대한중국학회 2020 중국학 Vol.73 No.-

본 논문은 현대중국어 客套语의 활용현황과 특징을 고찰하였다. 중국어 교육 내에서 특히 비즈니스 중국어 학습자들에게 필요한 부분이라고 판단되어, 비즈니스 목적의 중국어 교재에 수록된 客套语의 제시 상황을 분석하였다. 비즈니스 화행에 따라 안부 및 소개, 부탁 및 요청, 사과 및 양해 구하기, 감사, 접대 및 선물하기로 분류하였다. 주요 고찰 결과와 시사점을 토대로 향후 연구에서는 등급별, 수준별 교육 내용과 방안을 논의할 계획이다. 관련 후속 연구가 활발히 이어져 한층 더 효과적인 客套语 교육 방법이 마련되어 중국어 교육 현장에 활용되길 기대한다. The purpose of this study is to analyze various modern Chinese polite greetings and their characteristics, and to find educational contents and plans that can be applied to Chinese language education based on the analysis results. This study also aims at examining how and to what extent education on polite greetings is being carried out in an actual Chinese language education. Previous studies have mainly focused on identifying the differences between 客气话, 客气词语, and polite greetings, and categorizing them by use according to their definitions and other criteria. This study all the categories suggested in previous studies were included in the analysis made in this study. This study considered that polite expression education is an essential part in Chinese language education, especially for business Chinese learners. Therefore, the study comprehensively analyzed the contents related to polite greetings contained in Chinese textbooks for business purposes and the dialogue situations in which they are used. For the analysis of the example sentences used in the textbooks, the examples were classified into the categories of “give regards and introduce,” “ask and request,” “apologize and request for understanding,” “express gratitude,” “congratulate and praise,” and “present a gift” based on the business speech act. The major findings and their implications are as follows. First, most of the textbooks presented only the meanings of the words in a brief way, without explaining their significance and characteristics as polite greetings. Second, while 『现代汉语词典』 does not include any indications of polite greetings, some words or expressions that meet the conditions of polite greetings were found when taking into account pragmatic factors such as the situations and purposes of dialogue and the relationships of the communicators. Third, most of the social greetings have corresponding expressions as responses. These expressions are included in a broader scope of polite greetings. In this context, regardless of whether a polite greeting has a typical response or not, if there is an expression usually used together with a polite greeting, it is desirable to present both for the convenience of learners. Fourth, if a word has more than two meanings, it is necessary to determine whether it is used as a polite greeting.