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Serratia marcescens 로 부터 두 가지 형태의 acetolactate Synthease 분리와 성질
양정희,김승수 ( Jeong Hee Yang,Soung Soo Kim ) 생화학분자생물학회 1992 BMB Reports Vol.25 No.1
Two forms of Serratia marcescens acetolactate synthase (designated ALS I and ALS II) have been separated by utilizing DEAE-Sephacel column chromatography with the combination of stepwise and a linear gradient elution of increasing ionic strength. The native molecular weights of the two forms of ALS as determined by Sephacryl S-400 gel filtration method appears to be 572,000 and 531,400 for ALS I and ALS II, respectively. Feedback inhibition studies indicate that ALS I is far more sensitive to inhibition by valine, leucine and isoleucine than ALS II. On the other hand, ALS II is far more sensitive to α-ketobutyrate inhibition than ALS I. The two forms of ALS also have differences in sensitivity against two different classes of herbicides, sulfonylurea and imidazolinone. These data suggest that the two forms of ALS are physically and functionally distinct.
국가 암조기검진사업 성과에 영향을 미치는 요인 - 보건소 및 사업실무자 특성을 중심으로 -
최귀선,양정희,계수연,이선희,신해림,김창민,박은철,Choi, Kui-Son,Yang, Jeong-Hee,Kye, Su-Yeon,Lee, Sun-Hee,Shin, Hai-Rim,Kim, Chang-Min,Park, Eun-Cheol 대한예방의학회 2004 예방의학회지 Vol.37 No.3
Objectives : Cancer is the leading cause of death in Korea. Therefore, a National Cancer Screening Program (NCSP) was launched in 1999. This study planned to evaluate the performance of the NCSP to identifying the influencing factors in relation to characteristic public health centers. Methods : To analyze the performance, the database of the NCSP records for 2002 was used. The performance index was measured by the goal achievement rate, which was defined by the real number of screenees against the expected number of screenees. Also, a survey was conducted by a self-administered questionnaire to identify the factors associated with the goal achievement rate. The questionnaire was divided into two sections. In the first section, the individual characteristics of the program coordinator in each public health center were measured, and second section was comprised of questions about the organizational characteristics associated with the NCSP. A total of 121 subjects from 241 public health centers completed the questionnaire. Results : Of the 121 public health centers (50.2% response rate), the average goal achievement rate was 72.8%. The results of the regression model showed that public health centers located in rural area (parameter estimates=38.2) and had great support from a head of center or province (parameter estimates=0.20) and tended to have higher goal achievement rates. However, the characteristics of the program coordinator, especially their knowledge of and attitude toward cancer screening, were not significantly related to the goal achievement rates. Conclusions : It appears that the most important associated factors to the goal achievement rate in the NSCP were the location of the public health center and the support for the NCSP from the head of the center or province.
임민경,박숙경,양정희,이영성,Lim, Min-Kyung,Park, Sook-Kyung,Yang, Jeong-Hee,Lee, Young-Sung 대한예방의학회 2003 예방의학회지 Vol.36 No.1
Objectives : To investigate the availability and demand for overall cancer-related information, and to establish a basic plan for the construction of a cancer database and information system based on the research results from Korea. Methods : Postal and telephone surveys were carried out, between August 2001 and November 2001, of 323 affiliated faculty professors from medical universities and colleges in Korea. The data were analyzed with descriptive statistical methods, with regard to the present status and demand for health and cancer-related information. Results : Most (over 80%) subjects studied utilized the health-related information provided on Internet website from foreign countries, such as Medline, but similar comprehensive information system lacked in Korea. The construction of a cancer-related database of domestic research results was revealed to be in a great demand. Information on registration and statistics (52.8%), study results (48.5%) and study resources (37.4%) were the major ingredients required in the database. In constructing a database of the cancer-related research results, a full-text service, continuous updating of data, and the development of standardized user-friendly searching tool were regarded as the necessary components. The formulation of an information sharing system, regarding cancer-related clinical trials, was investigated as being quite feasible. Conclusion : This study demonstrated the great importance of cancer information systems, and much demand for an available cancer-related database based on Korean research results.
곽민선,성나영,양정희,박은철,최귀선,Kwak, Min-Son,Sung, Na-Young,Yang, Jeong-Hee,Park, Eun-Cheol,Choi, Kui-Son 대한예방의학회 2006 예방의학회지 Vol.39 No.4
Objectives: The goal of this study is to measure women's willingness to pay for cancer screening and to identify those factors associated with this willingness to pay. Methods: A population-based telephone survey was performed on 1,562 women (aged 30 years or over) for 2 weeks (9-23th, July, 2004). Data about sociodemographic characteristics, health behaviors, the intention of the cancer screenings and willingness to pay for cancer screening were collected. 1,400 respondents were included in the analysis. The women's willingness to pay for cancer screening and the factors associated with this willingness to pay were evaluated. Results: The results show that 76% of all respondents have a willingness to pay for cancer screening. Among those who are willing to pay, the average and median amount of money for which the respondents are willing to pay are 126,636 (s.d.: 58,414) and 120,000 won, respectively. As the status of education & the income are higher, the average amount that women are willing to pay becomes much more. The amount of money women are willing to pay is the highest during the 'contemplation' stage. Being willing to payor not is associated with a change of behavior (transtheoretical model), the income, the concern about the cancer risk, the family cancer history, the marital status, the general health exam, age and the place of residence. Income is associated with a greater willingness to pay. Old age was associated with a lower willingness to pay. Conclusions: According to the two-part model, income and TTM are the most important variables associated with the willingness to pay for cancer screening. The cancer screening participation rate is low compared with the willingness to pay for cancer screening. It is thought that we have to consider the participants' behavior that's associated with cancer screening and their willingness to pay in order to organize and manage cancer screening program.
원저(原著) : 철 결핍성 빈혈에서의 ZPP의 임상적 이용
김은지 ( Eun Jee Kim ),양정희 ( Jeong Hee Yang ),송운흥 ( Woon Heung Song ) 대한임상병리사협회 1996 임상혈액검사학회 발표자료집 Vol.3 No.1
The measurement of zinc protoporphyrin(ZPP) in the red blood cells is used for a screening test of IDA. When iron supply is insufficient or iron utilization is impaired, zinc is chelated in a parallel reaction instead of iron. In this paper we analyze the efficiency of the ZPP test as the detection method for the IDA. We measured ZPP using hematofluorometer and compared with the results of Hb, Hct, MCV, ferritin, TIBC and iron in 167 patients. The result revealed that measurement of ZPP is a sensitive and specific test for diagnosis of iron deficiency anemia. The sensitivity and specificity of ZPP to IDA are 90.2% and 87.3% respectively. We concluded that measurement of ZPP using Hematofluorometer is an economical, rapid, easy and accurate diagnostic test in iron deficiency anemia.
2009 Influenza A H1N1 감염 중 소아 중증 환자에 대한 고용량 Oseltamivir 투여 효과
조현석 ( Hyun Seok Cho ),민세라 ( Se Ra Min ),이준호 ( Joon Ho Lee ),안성연 ( Sung Yeun Ahn ),이현수 ( Hyeon Soo Lee ),양정희 ( Jeong Hee Yang ),김자경 ( Ja Kyoung Kim ) 대한천식알레르기학회 2014 Allergy Asthma & Respiratory Disease Vol.2 No.1
Purpose: We aimed to evaluate the use and safety of double dose oseltamivir for patients manifesting severe respiratory symptoms or showing no improvement of clinical symptoms after 72 hours’ treatment with the usual oseltamivir dosage. Methods: We analyzed the clinical features of 2009 influenza A H1N1 inpatients who had been admitted to a university hospital’s Department of Pediatrics between August 2009 and January 2010. The Influenza A H1N1 diagnoses were confirmed by real-time reverse transcriptase polymerase chain reaction. Results: The study participants numbered 157 (mean age, 5.0 years; male-to-female ratio, 1.1:1). Among them, twenty (mean age, 5.2 years) were administered double dose oseltamivir. This double dose group showed higher peak body temperatures and more abnormal radiologic results than the other, usual-dose group. The mean time duration between high fever and afebrile status after initiation of double-dose oseltamivir administration was 2.1 days, whereas that within the usual-dose group was 1.7 days. There were no adverse effects in the patients treated with double-dose oseltamivir. Conclusion: Double-dose oseltamivir was well tolerated in patients with severe 2009 influenza A H1N1 infection. (Allergy Asthma Respir Dis 2014;2:64-69)
양정희,홍경표 中部大學校 農業生命資源科學硏究所 1998 農業生命資源科學硏究論文集 Vol.6 No.-
From 2001, Korean beef market will be perfect opened, and now Korean native cattle industry must adjust more good productivity system. But Korean native cattle market, include another cows, are very weak and It's can't compared export country as USA and Australia. In 1991 Japanese beef market were opened before Korean beef market. It's indicated to us that imported beef were very storing in japanese market. And imported beef, expecially imported USA, were sprayed wide in Japanese market. In 1996 imported beef share 50% over in Japanese market. Inspite of Japanese has good grading system which separated 15 drgree of carcass beef. But Japanese native cattle(beef) named WHAU, are keeping their market share in Japan. It's shows that excellent degree beef are favourited their people. If Korean native beef are wanted to 50% over market share in Korean market, Korean beef farmer muse more good breeding system as well as Japan or USA. And Korean beef farmers must up to productivity more excellence beef, which makes to favorite Korean people.