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임수영 한국어문교육연구회 2010 어문연구 Vol.38 No.1
This thesis research the character of Korean modern poetry by examining the current condition of poetry bestseller and new trends of poetic creation in the view of ‘relationship' and ‘consumption' which represent capitalism and mass media. The former study the popularity of korean modern poetry, the factor of made poetry bestseller in the aspect of awareness of poet formating by education system and medium exposure. And this research searches the popularity of poetry bestseller and influence of popular reader's potential capability as independent consumer in the fields of culture and literature. The latter study the extension of poetic text in recent poetry made by relationship in both media communication and alternation with other genre of literature, culture genre or mass media. By doing this, it searches the connection of popularity and the essence of poetry, also seeks the new directivity of korean modern poetry. 본고는 資本主義와 大衆媒體를 표상하는 ‘消費’와 ‘有關性’의 측면에서 현대 시문학의 베스트셀러의 현황과 새로운 시문학의 창작 흐름을 살펴봄으로써 韓國現代詩의 특성을 고찰한다. 전자는 詩文學 장르의 베스트셀러를 형성하는 요인을 ‘制度敎育’과 ‘媒體露出’로 형성된 ‘詩人의 認知度’를 중심으로 고찰함으로써 경제적 ‘소비’의 측면에서 현대시 베스트셀러의 大衆性 문제를 살펴보고, 문화장르와 詩集의 주요 구매층인 대중독자층이 소비주체로서 지닌 잠재적 역량이 현재의 베스트셀러 현황에 미치는 영향을 타진해보는 작업이다. 또한 후자는 실험적 창작경향을 보이는 최근의 詩作들을 분석대상으로 삼아 ‘媒體性과의 疏通’과 ‘他 장르와의 交互’로 나눌 수 있는 ‘有關性’의 측면에서 현대시의 텍스트 擴大現象을 살펴보면서 현대시의 새로운 方向性을 고찰하는 작업이다.
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임수영,Lalita Subedi,신동윤,김충섭,이강노,김선여 한국응용약물학회 2017 Biomolecules & Therapeutics(구 응용약물학회지) Vol.25 No.5
Excessive activation of microglia causes the continuous production of neurotoxic mediators, which further causes neuron degeneration. Therefore, inhibition of microglial activation is a possible target for the treatment of neurodegenerative disorders. Balanophonin, a natural neolignoid from Firmiana simplex, has been reported to have anti-inflammatory and anti-cancer effects. In this study, we aimed to evaluate the anti-neuroinflammatory effects and mechanism of balanophonin in lipopolysaccharide (LPS)- stimulated BV2 microglia cells. BV2 microglia cells were stimulated with LPS in the presence or absence of balanophonin. The results indicated that balanophonin reduced not only the LPS-mediated TLR4 activation but also the production of inflammatory mediators, such as nitric oxide (NO), prostaglandin E2 (PGE2), Interleukin-1β (IL-1β), and tumor necrosis factor-α (TNF-α), in BV2 cells. Balanophonin also inhibited LPS-induced inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX2) protein expression and mitogen activated protein kinases (MAPKs), including extracellular signal-regulated kinase (ERK1/2), c-Jun Nterminal kinase (JNK), and p38 MAPK. Interestingly, it also inhibited neuronal cell death resulting from LPS-activated microglia by regulating cleaved caspase-3 and poly ADP ribose polymerase (PARP) cleavage in N2a cells. In conclusion, our data indicated that balanophonin may delay the progression of neuronal cell death by inhibiting microglial activation.
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A multi-enzyme cascade reaction for the production of α,v-dicarboxylic acids from free fatty acids
임수영,Hee-Wang Yoo,Sharad Sarak,김병기,윤형돈 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.98 No.-
α,v-Dicarboxylic acids (α,v-DCAs) have numerous applications, as raw materials for producing variouscommodities and polymers in chemical industry. For example, dodecanedioic acid (DDDA), a monomer ofnylon 612 polymer is used for numerous applications such as plasticizers and adhesive. In this study,firstly the enzymatic production of DDDA from corresponding v-hydroxy fatty acid was optimized usingaldehyde reductase (AHR) and aldehyde dehydrogenase (ALDH), and the cofactor imbalance andproficient regeneration thereof, is a major hurdle for the effective biosynthesis. To circumvent this, NAD(P)H oxidases (NOXs) from Lactobacillus brevis (LbrNOX), Brevibacterium glutamicum (BreNOX) andLactobacillus reuteri (LreNOX) were examined for the AHR/ALDH/NOX cascade and LreNOX was identifiedas suitable enzyme. Moreover, LreNOX was fused with AHR and employing this fusion protein inEscherichia. coli (E. coli) holding ALDH, nearly complete conversion (>99%) into DDDA was achieved from30 mM of 12-hydroxy dodecanoic acid within 12 h of whole-cell biotransformation (2.2-foldimprovement in productivity) turning out to be beneficial. Finally, the synthesis of DDDA fromcorresponding free fatty acid (dodecanoic acid), was performed by employing combination of AHR/ALDH/NOX cascade with CYP153AL.m, where 2.3 mM (0.53 g/L) of DDDA was produced in one-pot onestep.
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압출법을 이용한 골대체제용 다공성 인산칼슘 세라믹 개발
임수영,신동훈,천성수,양동준,김석영 한국생체재료학회 2010 생체재료학회지 Vol.14 No.4
Bone growth into a porous structure can be accelerated by the control of size, shape, volume and interconnectivity of the pores. The 3-dimensional interconnectivity of pore structures is one of important features for bone substitutes and tissue engineering scaffolds. The 3-D interconnected porous calcium phosphate ceramics were prepared using an extrusion method with a syringe in this study. The porosity and compressive strength were carefully examined upon the addition of PMMA (poly-methyl methacrylate) beads and HAp (hydroxyaptite) in a DCPD (dicalcium phosphate dehydrate-CN(calcium nitrate solution) system. Highly porous calcium phosphate ceramics having good compressive strength were obtained using a syringe extrusion method with PMMA beads and HAp. The highly macro- and microporous structured samples were obtained by the addition of PMMA beads and the reaction of DCPD-CN, respectively. The PMMA beads played the role of a sacrificial template for relatively large pores. The DCPD-calcium reaction generated the micro-pores and channels and connected the large pores which were formed by PMMA beads. The addition of HAp were significantly increased the compressive strength with decreasing porosity. The addition of HAp were also enhanced the phase transformation of calcium phosphates (TCP, CaO, etc) to HAp crystalline. The control of HAp formation can be applied for the control of the biodegradation rate of calcium phosphate. These porous calcium phosphate ceramics with high porosity and compressive strength can be applied for dental and orthopedic areas as a bone substitute materials
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윤동주 시와 민속: 자연 상징과 문답식 구조의 민속적 연계성 연구
임수영 국립경국대학교 민속학연구소 2024 공동체문화와 민속 연구 Vol.8 No.-
This study examines the folk elements in Youn Dong-ju’s poetry and explores the multilayered meanings of his work. While Youn Dong-ju’s poetry is often analyzed through themes like resistance, nationalism, Christianity, introspection, and lyricism, this paper specifically focuses on its connections to folk traditions. The study begins by assessing how Youn Dong-ju’s background—his upbringing in Northern Manchuria, the Confucian and folk influences on his ancestors, the unique characteristics of Christianity in the region, and his diasporic experiences—shaped his poetry. Chapter 2 analyzes the symbolic meanings of natural elements in Youn Dong-ju’s poetry, such as the sky, stars, and wind, in relation to folk traditions. Rather than merely depicting natural phenomena, these elements are used to convey deeper existential reflections. The study shows how folk beliefs use nature to express intangible ideas, providing an interpretive framework that extends beyond traditional religious and self-reflective readings. Chapter 3 explores the dialogical structure in Youn Dong-ju’s poetry, highlighting its folk characteristics. This analysis traces the influence of traditional Korean poetic forms and folk songs on his work, noting how Youn Dong-ju’s interest in contemporary poets and the resurgence.
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