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곽민선,박은철,방진영,성나영,이지영,최귀선,Kwak, Min-Son,Park, Eun-Chul,Bang, Jin-Young,Sung, Na-Young,Lee, Ji-Young,Choi, Kui-Son 대한예방의학회 2005 Journal of Preventive Medicine and Public Health Vol.38 No.4
Objectives : We wanted to identify those factors associated with stomach, colon, breast and cervix cancer screening. Methods : A population-based telephone survey was conducted for 2 weeks (the 9th-23th of July, 2004) by trained interviewers with using a questionnaire. 2,598 respondents (females aged 30 years or over, and the males aged 40 years or over) were selected by random-digit dialing that was based on the 2000 Population and Housing Census. The data on socio-demographic, health behavior and enabling factors were collected. 2,571 respondents were included in analysis. The cancer screening rate was classified into 2 categories : the life time screening rate and the screening rate with recommendations. Results : For the 2,571 respondent s, the life time screening rate was as follows: 52.0% (Stomach), 25.3% (Colon), 55.9% (Breast) and 76.8% (Cervix). The screening rate with recommendation was as follows : 3 9.2% (Stomach), 20.6% (Colon), 42.5% (Breast) and 58.3% (Cervix). On a multiple logistic regression analysis of the life time screening, statistically significant relationships were observed for the screening intention, the health exam, the disease history, the age of the patients and the cancer screening rates. On a multiple logistic regression analysis of the screening with recommendation, statistically significant relationships were observed for the screening intention, the health exam, the age of the patients, the concern about the risk of cancer, the voluntary health insurance for cancer and the cancer screening rates. Conclusions : The results of this study suggest that the cancer screening intention, the health exam and the age of the patients are the most important factors to participate in life time cancer screening and also screening with recommendations. A positive association was also observed for the concern about the risk of cancer, the voluntary health insurance for cancer. It is hoped that this study will be a base line data for suggesting the representative cancer screening rate in Korea.
곽민선,정인화,김위종,최혜원,한진영 대한진단검사의학회 2021 Laboratory Medicine Online Vol.11 No.4
Loss of chromosome Y (-Y) is one of the most common somatic genomic alterations in the male hematopoietic system. However, it has been widely debated whether -Y is an aging-related phenomenon or a disease-associated abnormality. Literature reviews, recent molecular genetic findings, and cytogenetic data obtained from the Dong-A University Hospital over the last 12 years supported that 75–100% of metaphases with isolated -Y were primarily associated with myeloid malignancies, including myelodysplastic syndrome. Thus, we need to monitor the frequency of -Y in patients with unexplained causes of anemia or cytopenia. We observed that in our hospital, more than 75% of -Y cases were diagnosed in patients with non-Hodgkin lymphoma or multiple myeloma, raising concerns on the disease development process when considering the increasing prevalence of these diseases in the aging population. -Y in peripheral blood has been associated with an increased risk of mortality, lower life expectancy, autoimmune disorders, cardiovascular diseases, diabetes, and hematologic malignancies. Y chromosome genes are known to be expressed in reproductive tissues. Therefore, it is crucial to maintain a regulated balance between the expression of X and Y homolog genes for men to remain healthy. -Y는 남성의 조혈기관에서 발생하는 가장 흔한 체세포 유전체 이상 중 하나임에도 불구하고 노화와 관련된 현상인지 아니면 질병에 연관된 이상인지에 대해 논란이 있어왔다. 문헌고찰과 최근의 분자유전학적인 연구, 그리고 본원의 12년에 걸친 증례분석을 통해 75% 이상의 중기세포에서 관찰되는 -Y 단일이상은 특히 MDS를 포함한 골수계 혈액종양과 관련됨을 알 수 있어서 원인불명의 빈혈이나 혈구감소에 동반될 때 지속적인 경과관찰이 필요하다고 생각된다. 본원에서는 비Hodgkin림프종 및 MM 환자에서도 75% 이상으로 -Y가 관찰된 예가 있어서 인구의 고령화와 함께 그 추이를 살펴볼 필요가 있겠다. 말초혈액에서 관찰되는 -Y는 혈액종양 이외에 전반적인 높은 사망률 및 낮은 기대수명, 자가면역질환, 심혈관질환, 당뇨 등과 연관되고, Y염색체 관련 유전자발현이 비생식계 조직에서도 확인되고 있으므로, X-Y 상동성유전자 쌍 사이에 안정되고 균형 있는 발현을 유지하는 것이 남성에서 건강에 중요하다고 할 수 있다.
곽민선,성나영,양정희,박은철,최귀선,Kwak, Min-Son,Sung, Na-Young,Yang, Jeong-Hee,Park, Eun-Cheol,Choi, Kui-Son 대한예방의학회 2006 예방의학회지 Vol.39 No.4
Objectives: The goal of this study is to measure women's willingness to pay for cancer screening and to identify those factors associated with this willingness to pay. Methods: A population-based telephone survey was performed on 1,562 women (aged 30 years or over) for 2 weeks (9-23th, July, 2004). Data about sociodemographic characteristics, health behaviors, the intention of the cancer screenings and willingness to pay for cancer screening were collected. 1,400 respondents were included in the analysis. The women's willingness to pay for cancer screening and the factors associated with this willingness to pay were evaluated. Results: The results show that 76% of all respondents have a willingness to pay for cancer screening. Among those who are willing to pay, the average and median amount of money for which the respondents are willing to pay are 126,636 (s.d.: 58,414) and 120,000 won, respectively. As the status of education & the income are higher, the average amount that women are willing to pay becomes much more. The amount of money women are willing to pay is the highest during the 'contemplation' stage. Being willing to payor not is associated with a change of behavior (transtheoretical model), the income, the concern about the cancer risk, the family cancer history, the marital status, the general health exam, age and the place of residence. Income is associated with a greater willingness to pay. Old age was associated with a lower willingness to pay. Conclusions: According to the two-part model, income and TTM are the most important variables associated with the willingness to pay for cancer screening. The cancer screening participation rate is low compared with the willingness to pay for cancer screening. It is thought that we have to consider the participants' behavior that's associated with cancer screening and their willingness to pay in order to organize and manage cancer screening program.
신문자료를 활용한 ARCS 수업전략의 적용 효과 : 중학교 2학년 과학 "호흡과 배설" 단원을 중심으로
곽민선,김선영,문두호 韓國生物敎育學會 2013 생물교육 Vol.41 No.4
This study investigated the effects of "ARCS strategy using newspapers" on middle school students' academic achievement, science related attitude and science learning motivation. Six classes of 184 students in the 2nd grade participated in this study. The experimental group, consisted of 3 classes, was taught with the instruction method of "ARCS model using NIE", while the control group of other 3 classes was taught with the traditional instruction method. The experimental group used the newspapers related to the respiration and excretion unit in order to arose students' Attention, Relevance, Confidence and Satisfaction. The study results indicated that the instruction method of "ARCS strategy using newspapers" was more effective in improving students' science academic achievement, attitude toward science, as well as science learning motivation compared to the traditional instruction method. More specifically, the experimental group students represented the statistically higher scores on all of the four motive elements (Attention, Relevance, Confidence and Satisfaction), compared to the control group students. Finally, students perceived that the instruction of "ARCS model using NIE" aroused interest in science class, attracted active participation and helped to acquire science knowledge.