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손건호,김주선,강삼식,김현표,장현욱 영남대학교 약품개발연구소 1994 영남대학교 약품개발연구소 연구업적집 Vol.4 No.-
Two flavonoids, diosmetin 7-O-glucoside and lonicerin, and an iridoid, vogeloside have been isolated from the aerial parts of Lonicera japonica(Caprifoliaceae). The structures of these isolates have been determined by chemical transformations and interpretation of the spectral data. This is the first report of the isolation of diosmetin 7-O-glucoside from this plant.
손건호,정근영,도재철,Son, Kun-Ho,Jung, Keun-Young,Do, Jae-Chul 한국생약학회 1993 생약학회지 Vol.24 No.3
Three compounds were isolated from the rhizomes of Dioscorea quinqueloba and identified as $diosgenin\;3-O-{\alpha}_-L-rhamnopyranosyl(1{\rightarrow}2)-{\beta}-_D-glucopyranoside$, dioscin and gracillin by chemical and spectroscopic means.
손건호,김소희,정근영,장현욱,Son, Kun-Ho,Kim, So-Hee,Jung, Keun-Young,Chang, Hyeun-Wook 한국생약학회 1994 생약학회지 Vol.25 No.2
The platelet activating factor (PAF) is a newly discovered chemical mediator, the chemical structure of which is 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine. Since PAF has potent and broad activities, its pathophysiological roles have received much attention. To develope a new PAF antagonist from medicinal plants, extracts of twenty medicinal herb were screened using PAF receptor binding, $[^{14}C]$ serotonin release and platelet aggregation.
손건호,김소희,정근영,장현욱 영남대학교 약품개발연구소 1994 영남대학교 약품개발연구소 연구업적집 Vol.4 No.-
The platelet activating factor (PAF) is a newly discovered chemical mediator, the chemical structure of which is 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine. Since PAF has potent and broad activities, its pathophysiological roles have received much attention. To develope a new PAF antagonist from medicinal plants, extracts of twenty medicinal herb were screened using PAF receptor binding, [^(14)C] serotonin release and platelet aggregation.
단삼(Salvia miltiorrhiza Bunge)으로 부터 Tanshinone IIA의 분리 및 함량분석
손건호,박미정,이승호,박정일,강신정,장승엽,이경순 영남대학교 약품개발연구소 1999 영남대학교 약품개발연구소 연구업적집 Vol.9 No.-
The rhizomes of Salvia miltiorrhiza Bunge(Labiatae) has been used in Chinese traditional medicine for the treatment of coronary heart diseases and myocardial infarction. As a part of a research for standardization of crude oriental drugs, we have determined the content of tanshinone IIA in Salvia miltiorrhiza pur-chased from various regions of Korea. The HPLC method by which quantitative analysis was conducted, showed reproducible results and chromatographic iso-lation of tanshinone IIA was accomplished successively.