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유방의 침윤성 관암종에서 핵등급 기준으로서 핵크기의 의의
배영경,김동석,최혜정,구미진,이수정,이제영,Bae, Young-Kyung,Kim, Dong-Sug,Choi, Hye-Juug,Gu, Mi-Jin,Lee, Soo-Jung,Lee, Jea-Young 대한세포병리학회 1999 대한세포병리학회지 Vol.10 No.1
To make the objective standard of nuclear size ingrading nuclear pleomorphism of invasive ductal carcinoma of the breast, we measured maximal nuclear diameter of tumor cells on imprint cytology slides and histologic sections from 65 cases by using computer-based image analysis system(Optimas 6.0). The maximal diameter of red blood cells were also measured to evaluate the ratio of maximal nuclear diameter of tumor cells to maximal diameter of red blood cells. The mean values of maximal nuclear diameter of tumor cells on imprint cytology slides and histologic sections were $7.56{\mu}m,\;7.53{\mu}m$ in nuclear grade 1, $8.92{\pm}0.98{\mu}m,\;9.02{\pm}0.74{\mu}m$ in nuclear grade 2, and $12.90{\pm}1.47{\mu}m,\;12.44{\pm}1.41{\mu}m$ in nuclear grade 3, respectively. There were no significant differences between values of imprint cytology and histologic section. The ratio of maximal nuclear diameter of tumor cells to maximal diameter of red blood cells were 1.3-1.4:1 in nuclear grade 1, 1.6-1.7:1 in nuclear grade 2, and 2.2-2.3:1 in nuclear grade 3. These values would be guidelines for grading nuclear pleomorphism of invasive ductal carcinoma of the breast on routine surgical pathology work.
줄기세포를 이식한 척수손상 흰쥐에서 반복자기자극의 효과
배영경,박해운,조윤우,김수정,이준하,권정구,안상호,Bae, Young-Kyung,Park, Hea-Woon,Cho, Yun-Woo,Kim, Su-Jeong,Lee, Joon-Ha,Kwon, Jung-Gu,Ahn, Sang-Ho 대한물리치료학회 2010 대한물리치료학회지 Vol.22 No.1
Purpose: We tested whether repetitive transcranial magnetic stimulation (rTMS) improved recovery following spinal cord injury (SCI) in rats with transplantation of adipose tissue-derived stromal cells (ATSCs). Methods: Twenty Sprague-Dawley rats (200-250 g, female) were used. Moderate spinal cord injury was induced at the T9 level by a New York University (NYU) impactor. The rat ATSCs (approximately $5{\times}10^5$ cells) were injected into the perilesional area at 9 days after SCI. Starting four days after transplantation, rTMS (25 Hz, 0.1 Tesla, pulse width=$370{\mu}s$, on/off time=3 sec/3 sec) was applied daily for 7 weeks. Functional recovery was assessed using the Basso, Beattie, and Bresnahan (BBB) locomotor rating scale as well as pain responses for thermal and cold stimuli. Results: Both groups showed similar, gradual improvement of locomotor function. rTMS stimulation decreased thermal and cold hyperalgesia after 7 weeks, but sham stimulation did not. Conclusion: rTMS after transplantation of ATSCs in an SCI model may reduce thermal hyperalgesia and cold allodynia, and may be an adjuvant therapeutic tool for pain control after stem cell therapy in SCI.
배영경 ( Young Kyung Bae ) 영남대학교 기초/임상의학연구소 2007 Yeungnam University Journal of Medicine Vol.24 No.2S
Breast conserving surgery has become the preferred method of treatment for breast cancer. Therefore clear surgical margin is critical to minimize the risk of local recurrence. Although paraffin section of inked surgical margin is the gold standard for margin assessment, this process is time consuming, and results are not available until after the operation. Several methods of intraoperative margin assessment are available including gross evaluation of the tumor specimen, specimen slice radiography, pathologic evaluation with touch preparation cytology or frozen section analysis. Here I review three methods of pathologic evaluation -macroscopic evaluation, touch preparation cytology, and frozen section- and deal with problems and pitfalls that can happen in routine diagnostic fields.
착색성 융모결절성 활막염의 세침흡인 세포학적 소견 - 1예 보고 -
최준혁,배영경,심영란,김미진,최원희,Choi, Joon-Hyuk,Bae, Young-Kyung,Shim, Young-Ran,Kim, Mi-Jin,Choi, Won-Hee 대한세포병리학회 1999 대한세포병리학회지 Vol.10 No.2
Pigmented villonodular synovitis is a destructive, fibrohistiocytic proliferation producing innumerable villous and nodular synovial protrusions. Its common locations are knee, ankle, foot, and hip. Although histologic feature of this tumor is well known, there have been few reports on the fine needle aspiration cytology findings. We report the cytologic features of a biopsy-proven case oi pigmented villonodular synovitis. The patient was a 21-year-old male with a mass of the right knee for 2 years. On fine needle aspiration cytology, the aspirates was composed of abundant mononuclear histiocytic cells, singly and in clusters, multinucleated slant cells, and hemoslderin pigments.
구미진,배영경,김미진,최준혁,최원희,Gu, Mi-Jin,Bae, Young-Kyung,Kim, Mi-Jin,Choi, Joon-Hyuk,Choi, Won-Hee 대한세포병리학회 2000 대한세포병리학회지 Vol.11 No.1
Extraskeletal osteosarcoma is an uncommon tumor originated from soft tissue without evidence of skeletal involvement. It usually affects adults and its common locations are extremity, buttock, and retroperitoneum. Although the histologic feature of this tumor is well known, there have been few reports on the fine needle aspiration cytologic findings. We report the imprint cytologic feature of extraskeletal osteosarcoma. The patient was a 49-year-old man with a mass of the left anterior chest for 2 years. On the Imprint preparation, the smears showed malignant round, polygonal or spindle cells with coarsely clumped chromatin and occasionally prominent nucleoli. The malignant cells occur singly, in clusters, or associated with amorphous eosinophilic osteoid. Mitotic figures are also seen.
균상식육종의 단파장 자외선 B치료 및 국소 스테로이드제제 도포 중 발생한 림프종양 구진증
박정영 ( Jeong Young Park ),신동훈 ( Dong Hoon Shin ),최종수 ( Jong Soo Choi ),배영경 ( Young Kyung Bae ) 대한피부과학회 2013 대한피부과학회지 Vol.51 No.10
Patients with lymphomatoid papulosis have other lymphomas in 10∼20% of cases, most commonly mycosis fungoides, Hodgkin`s disease, and anaplastic large cell lymphoma. In a series involving at least 40 patients with lymphomatoid papulosis, the association of lymphomatoid papulosis with mycosis fungoides ranged from approximately 7% to 18%. It is most important to distinguish lymphomatoid papulosis from CD30-positive large cell transformation of mycosis fungoides. Both conditions can be distinguished on clinical grounds, and clinical course is often the only distinguishing feature. We report a case of lymphomatoid papulosis developing in an mycosis fungoides lesion in a patient who received 3 rounds of narrow band UVB phototherapy and topical corticosteroid application. (Korean J Dermatol 2013;51(10):801∼805)
분화가 좋지 않은 윤활막육종 접착도말의 세포학적 소견 - 1예 보고 -
구미진,최준혁,배영경,Gu, Mi-Jin,Choi, Joon-Hyuk,Bae, Young-Kyung The Korean Society for Cytopathology 2003 대한세포병리학회지 Vol.14 No.1
Poorly differentiated synovial sarcoma is a variant of synovial sarcoma. We report a case of poorly differentiated synovial sarcoma imprinted after resection. The patient was a 47-year-old woman with a right shoulder pain for 6 months. The cytologic features showed malignant round to oval, monotonous tumor cells with high nuclear to cytoplasmic ratio. Some tumor cells showed perivascular distribution and nuclear melding. Vague rosette-like structures were seen. On immunohistchemical stains, tumor cells were diffusely positive for CD99 and focally positive for epithelial membrane antigen. Ultrastructural examination showed desmosomes and microvilli.
전수경,박귀화,송필현,배영경,김성용,Jun, Soo Koung,Park, Kwi Hwa,Song, Phil Hyun,Bae, Young Kyung,Kim, Seong Yong 연세대학교 의과대학 2016 의학교육논단 Vol.18 No.3
The purpose of this study is to examine the factors that influence school life satisfaction based on personal variables, self-esteem, interpersonal relationships, and perception of the educational environment at a medical school in Korea. The data were collected from 228 medical students who agreed to participate in the study at a medical school. The Dundee Ready Medical Environment Measure (DREEM) and the self-esteem scale by Rosenberg were used. Questions measuring satisfaction of medical school life and interpersonal relationships (with professors, with senior/junior students, and with friends) were asked using a 5 point Likert scale. The data were analyzed by t-test, analysis of variance, and multiple regression analysis. The satisfaction of medical school life of male students was significantly higher than female students and increased with years of schooling. In DREEM, the students' perception of teachers decreased by school years. The relationship with senior and junior students of third year students was higher than other school years. The result of the regression analysis to determine the variables that affect satisfaction of medical school life showed that interpersonal relationships with senior and junior students, the students' social self-perception, and the students' perception of learning were significant. The results of this study will help medical schools in their plans to improve the level of satisfaction for the happiness and successful academic achievements of their students.
일개 농촌지역 노인의 아포지단백 E 다형성과 인지기능 변화
김상규,황태윤,이경수,강복수,조희순,배영경,Kim, Sang-Kyu,Hwang, Tae-Yoon,Lee, Kyeong-Soo,Kang, Pock-Soo,Cho, Hee-Soon,Bae, Young-Kyung 대한예방의학회 2009 예방의학회지 Vol.42 No.4
Objectives : The aim of this study is to examine the cognitive function change related to aging, the incidence of cognitive impairment, and the association between apolipoprotein E polymorphism and cognitive impairment through a follow-up of the elderly with normal cognitive ability at baseline. Methods : Two hundred and fifteen subjects aged 65 and over were surveyed in February, 1998 (baseline survey), and their cognitive function was assessed again in 2003 1st follow-up) and the once again in 2006 (2nd follow-up). Ninety one subjects completed all surveys up through the 2nd follow-up and their cognitive function scores using MMSE-K (Korean Version of the Mini-Mental State Examination) and the distribution of apolipoprotein E allele were analyzed. Results : The cognitive function scores decreased with aging and the difference between baseline and the 2nd follow-up scores of the study increased with the age group. The incidence rate of cognitive impairment through an 8-year follow-up was 38.5% and higher in older age groups. Age was the only significant factor for incidence of cognitive impairment, but there was no significant association between apolipoprotein E genotype and incidence of cognitive impairment. Conclusions : The cognition of the elderly decreased with aging and the association of apolipoprotein E genotype with incidence of cognitive impairment was not significant in this study. To confirm the association between apolipoprotein E polymorphism and incidence of cognitive impairment further studies will be needed.