Propolis 첨가에 의한 김치의 산패지연 효과

박인숙 배화여자대학 1999 培花論叢 Vol.18 No.-

We studied about propolis' effect on the prolongation of acidification of kimchi during its fermentation at 10℃. In the result of inhibitory effect of propolis on the growth of Lactobacillus plantarum in MRS broth, propolis didn't show the ability of the complet inhibition in growth but, showed the ability of bacteriostatic effect. All experimental groups such as 1.0, 1.5, and 2.0 % propolis-added kimchi produced propolis-specific and non-acceptible odors. In the experiment of 0.05, 0.1, and 0.5 % propolis-added kimchi fermentation, all experimental groups prolonged the acidification and showed better taste than that of control kimchi. Especially, 0.05 propolis-added kimchi showed the best taste among all of things. Microbial changes in propolis-added kimchi fermentation didn't show the strain-specific inhibitory effects of propolis, but showed that it caused the prolongation of acidification of kimchi by inhibition of lactic acid bacteria in the prior stages of kimchi fermentation. And the growth of yeast in kimchi fermentation was delayed by addition of propolis.

단일치아의 심한 치조골 소실 환자에서 블록형 자가치아골이식재를 이용한 치조능증대술: 증례보고

박인숙,Park, In-Sook 대한악안면성형재건외과학회 2012 Maxillofacial Plastic Reconstructive Surgery Vol.34 No.6

Horizontal and vertical ridge augmentation with implant placement was performed, using a block type of autogenous tooth bone graft in a 37-year old male patient. This material was very useful for the case of severe alveolar bone resorption of a single tooth. After 13 months, excellent bony healing was obtained and final restoration was performed successfully.

국내 항암제의 임상현황 및 항암제 임상시험 가이드라인

박인숙,김동섭,최기환,왕소영,임화경,오우용,김소희,강주희,방영주,김주일,Park, In-Sook,Kim, Dong-Seop,Choi, Ki-Hwan,Wang, So-Young,Lim, Hwa-Kyung,Oh, Woo-Young,Kim, So-Hee,Kang, Ju-Hee,Bang, Yung-Jue,Kim, Joo-Il 대한임상약리학회 2002 臨床藥理學會誌 Vol.10 No.2

The enormous cost, intensive time, and constant efforts are required the drug discovery and development of bringing new drug products to the marketplace. The past several years, KFDA approved new drugs developed by local pharmaceutical industries; that is Sunppla, Factive etc. In addition to, investigational new drug application (IND) was established to accelerate new drug development and harmonize with international standards in 2002. At this point of time it is urgent problem to develop ability of reviewing new drug applications (NDAs) scientifically and appropriately to ensure that new drugs are safe and effective. There are many scientific issues embedded in new drug approval process from non-clinical studies to phase 3 clinical trials; 1) sample size, 2) application of end point, 3) statistical method, and etc. However the overall relation between protocols/reports of clinical trials and the characteristics of domestic medical system has fully not been studied. There is also, no references or data for the point to be considered in drug approval process. On this background, the objectives of this study are introduction of guidelines for the requirement for approval or evaluation of safety/efficacy in other countries and presentation how to practice clinical trial for new oncologic products in the present situation of clinical trial. We hope that the guidelines contribute to providing methods of clinical trials and procedures, and evaluating method to develop chemotherapeutic agents.

간호학생의 성격유형에 따른 자아인식과 임상실습수행능력의 차이에 관한 연구

박인숙 ( In Sook Park ),구영애 ( Yeong Ae Ku ) 경희대학교 경영연구원 2013 의료경영학연구 Vol.7 No.1

This study is intended to identify how personalities of nursing college students are, how self-perception level is depending on their personalities and what relation exists between clinical practice capability of nursing college students based on Choi Mi Sook`s (2005) supplemented paper, which reinforced measuring tools developed by Lee Won-Hee, Kim Cho-Ja, Ryu Ji-Soo, Lee Hye-Sook, Kim Gyeong-Sook, Lim Seong-Min (1991) based on MBTI personality test and Ego-gram Check list of Korea Transactional Analysis Association and Six-Dimension Scale of Schwirian(1978). Therefore, this paper is intended to make individuals understand their personalities and advance them toward desirable direction, and supplement their weakness. Then consequently help them to become satisfactory nurses for their job and make them more efficient nursing human resources. From the results of this study, it is recognized that self-perception for nursing college student is different depending on their personalities and capabilities of clinical practice are also different for each student. And it`s required to develop education programs and strategy of practice suitable for personalities of students and operate them efficiently. Capability for clinical practice is proved to nourish problem-solving capability for nursing college students and enhance education-learning course for individual by learning and practicing technologies, knowledge and attitudes. In addition, this capability is believed to give them sufficient skills to play roles for specialized future nurses who are autonomous and creative. Therefore, this paper proposes that addressing the relation between self-perception and clinical practice capability depending on personality of nursing college students is helpful for qualitative enhancement of clinical practice education.

청소년의 건강증진 생활양식과 관련요인연구

박인숙,주현옥,이화자,Park In Sook,Joo Hyeon Ok,Lee Hwa Ja 한국아동간호학회 1997 Child Health Nursing Research Vol.3 No.2

The purpose of this study were to define the degree of performance in health promoting lifestyle and to identify the variable related to performance in health promoting lifestyle of adolescents. The subjects of this study were 469 adolescents in the 4 high schools. The sample data were collected using a purposive sampling method from July 1 to July 27. The collected data were analysed by using descriptive statistics, Pearson's correlation coefficients, and stepwise multiple regression with SPSS PC+ program. The results of this research were as follows. First, The means of performance in the health promoting lifestyle of adolescents revealed total 2.478 ; harmonious relationships 3.045, regular diet 2.236, professional health management 1.332, sanitary life 2.910, self regulation 2.558, emotional support 2.696, healthy diet 2.408, rest and sleep 2.651, exercise and activity 2.491, self actualization 2.466, diet control 2.408. The factor with the highest degree of performance was the harmonious relationships, whereas the one with the lowest degrees was the professional health management. Second, the relationship between the degree of performance in health promoting lifestyle and its related variable were as follows. (1) Performance in the health promoting lifestyle was significantly correlated with self esteem, self efficacy, health conception, perceived health status, mother's health promoting lifestyle, mother's health conception. (2) The most important factor that affects performance in the health promoting lifestyle of adolescents was self esteem. The combination of self esteem, health conception, mother's health promoting lifestyle, self efficacy, perceived health status accounted for 45.2% of the variance in health promoting lifestyle of adolescents.

남자 간호대학생의 학교생활 적응 과정

박인숙 ( In Sook Park ) 부산대학교 간호과학연구소 2011 글로벌 건강과 간호 Vol.1 No.2

Purpose: The purpose of this study was to identified the male student`s meaning system on their adaptation experience in department of nursing where female students are in the majority, Methods: Data were collected through the in-depth interview of 9 male student and analysed through the grounded theory methodology, Results: The behaviors of male students for department-adaption can be summarized as a ``being uncomfortable`` with female students in department of nursing. Conclusion: A specific strategy is needed to provide an environment that is helpful for males in integrating into and adapting to the nursing studying.

요통환자의 접골요법 체험에 대한 질적 연구

임보경 ( Bo Kyung Yim ),박인숙 ( In Sook Park ),이정화 ( Jeong Hwa Lee ),김보영 ( Bo Young Kim ),최선미 ( Sun Mi Choi ) 한방재활의학과학회 2012 한방재활의학과학회지 Vol.22 No.3

Objectives :The purpose of this study is to identify the essence of bone-arrangement therapy experienced by patients suffering from low back pain. Methods :The current study was approved by the institutional review board(IRB No. I-1110/005-001) and planned by phenomenological methods among qualitative studies. In-depth interviews with nine patients who visited and treated their low back pain in a bonesetter’s office at Busan were completed and was analyzed based on a Collaizzi’s phenomenological method. Results :The interviews were classified into five themes as follows : “Low back pain with large amounts of inconvenience”, “Repulsion to existing medical treatment”, “Treatment by hand is the best”, “Must hold out bone set therapy”, “Giving up more improvement or hope for keeping health”Patients often are misunderstood because they could not actively participate in social activities due to their low back pain or frustrated by their incompetence to finish their work on time. They also visited a hospital to treat their pain, but had no reaction even after getting an injection or rather felt worse due to formal treatment. At first, they felt nervous and in great pain during process of treatment, but after a certain period of treatment, they felt much easier in their back and refreshment. Conclusions :The therapeutic effects by a unique treatment called bone set experienced by patients suffering from lower back pain patients who have no effects from the institutional treatment were reported in the current study. Through this finding, it is considered that further study on more objective and detailed therapeutic effects should be conducted.

저면관비 방법으로 동절기 토마토 육묘시 추비 농도가 묘 생장과 상토의 화학성 변화에 미치는 영향

박인숙(In Sook Park),심창용(Chang Yong Shim),최종명(Jong Myung Choi) (사)한국생물환경조절학회 2017 시설원예‧식물공장 Vol.26 No.1

토마토를 저면관비 방법으로 육묘할 때 유묘 생장과 상토 무기원소 농도 변화에 적합한 추비의 종류 및 농도를 구명하기 위해 본 실험을 수행하였다. 육묘용 2종류의 동절기 혼합상토 피트모스 0-6mm(PM06)+perlite 1-2mm(PE2)(7:3, v/v)와 피트모스 5-15mm(PM515)+PE2(7:3, v/v)를 72공 플러그 트레이에 각각 충전하고 토마토 ‘도태랑다이아’ 종자를 파종하여 발아시킨 후 생장상에서 35일간 육묘하였다. 자엽형성기에 추비를 시작하였고 13-2-13, 15-0-15, 20-9-20(N-P₂O5-K₂O) 복합비료를 순서대로 처리하였다. 추비시 생육 단계별로 25mg·L<SUP>-1</SUP>의 농도차(N 기준)를 둔 3종류의 Program을 두어 시비하였으며, 플러그 트레이의 수분이 포화 기준으로 40-50%로 감소 하였을 때 저면관비하였다. 파종 후 1, 2, 4 및 5주째 혼합상토를 상부, 중간, 하부로 3등분하여 포화추출한 후 추출용액의 pH, EC 및 무기이온 농도를 분석하고, 5주후에 유묘생장을 조사하였다. 육묘 기간 중 상토의 pH는 PM06+PE2가 PM515+PE2 보다 높았으며, 하부와 중간이 상부보다 높은 경향이었다. EC는 PM06+PE2가 PM515+PE2보다 높았으며 평균적으로 상부가 하부보다 2배 이상 높았다. NH4-N과 K+ 농도는 2종류 혼합상토의 모든 시비 Program에서 육묘 후 5주까지 높아졌으며, PM06+PE2의 추비 프로그램 3에서 가장 높았다. NO₃-N농도는 PM06+PE2에서 육묘기간 동안 높아졌고 추비농도가 높을수록 그러한 경향이 뚜렷하였다. 지상부 생체중을 비롯한 유묘의 생장은 PM06+PE2의 추비 Program 2에서 가장 우수하였다. 따라서 2종류 혼합상토를 이용한 공정육묘시 13-2-13, 15-0-15 및 20-9-20을 순서대로, 질소 기준 25mg·L<SUP>-1</SUP>에서 125mg·L<SUP>-1</SUP>까지 육묘기에 따라 점차적으로 높여 추비하는 방법이 적합하다고 판단하였다. This research was conducted to investigate the influence of post-planting fertilizer concentrations on the growth of seedlings and changes of nutrient concentrations of media in tomato seedling production through sub-irrigation. Two root media such as peat moss (grade of 0 to 6 mm, PM06) plus perlite (grade of 1 to 2 mm (PE2)(7:3, v/v) and peat moss (grade of 5 to 15 mm, PM515) plus PE2 (7:3, v/v) were formulated and filled into 72-cell plug trays. After seeds of ‘Dotaerang Dia’ tomato were sown and germinated at 28℃, the trays were moved to greenhouse and seedlings were raised 35 days. When the cotyledons were emerged, post-planting fertilizers of 13-2-13, 15-0-15 and 20-9-20 (N-P₂O5-K₂O) were applied in a sequence. The fertilizer concentrations based on N in each plug stage were differed with 25 mg·L<SUP>-1</SUP> in three treatments. The fertilizer solutions were supplied when the weight of plug trays decreased to 40 to 50% compared to container capacity. The root media were collected in 1, 2, 4, and 5 weeks after sowing and were divided into top, middle, and bottom parts, then were analysed for pH, EC and macronutrient concentrations. The seedling growth was investigated 5 weeks after sowing. The pH and EC in PM06+PE2 was higher than those of PM515+PE2. The bottom and mid-part had higher pH and lower EC compared to upper part in each medium. The differences of EC between upper and bottom parts were around 2 times in each medium. The NH₄-N and K concentrations in program 3 of PM06+PE2 showed the highest concentrations among all treatments. The NO₃-N concentrations in PM06+PE2 increased gradually and this rising tendency become severe as postplanting fertilizer concentrations were elevated. The seedling growth in terms of fresh and dry weights was the highest in the treatment of program 2 in PM06+PE2 among all treatments tested. Above results indicate that the gradual increases of fertilizer concentrations from 25 to 125 mg·L<SUP>-1</SUP> in plug stages 2, 3, and 4 plug stages are desirable for raising of tomato seedlings.

두기지 강도의 유산소운동과 저항운동을 병행한 복합훈련이 여성들의 체력과 혈중지질성분에 미치는 영향

박인숙(Park In Sook),정용수(Jung Yong Soo),이길우(Lee Kil Woo),이장규(Lee Jang Kyu),채 에스더(Tchai Esther) 한국여성체육학회 1999 한국여성체육학회지 Vol.13 No.1

The purpose of this study was to examine the effects of combining resistance training and two different intensity aerobic training on physical fitness and blood lipid profiles. Ten physically inactive female college students were randomly assigned to participate for l0wk in one of the following exercise groups: combined low intensity aerobic and resistance trained(LAERT: 25min walking with 50% of maxHR + resistance training for 3days/wk) and combined moderate intensity aerobic and resistance trained(MAERT: 25min jogging with 70% of maxHR + resistance training for 3days/wk). Before and after training, flexibility, sit-ups, one-repetition maximum for lat pull down, butterfly, leg extension, and leg curl ,and blood lipid profiles were determined. Both LAERT and MAERT groups demonstrated similar increase in 1RM butterfly(6kg and 7.5kg, respectively, p$lt;.05). Sit-ups for MAERT(30.25±1.09 to 32.25±0.69, p(.05) was significantly increased compared with LAERT(25.6±4.98 to 26.6±51, p(.05). Regarding on blood lipid profiles. TC and LDL-C decreased in both LAERT and MAERT. but only significantly in MAERT(200.8±9.0 to 174.6±4.4 for TC and 110.8118.71 to 89±21.61 for LDL-C, p$lt;.05). These data indicate that both LAERT and MAERT will provide concurrent increase in strength performance and reduces in TC and LDL-C after lOwk of training. However, the intensity of two different aerobic exercises does not seem to influence on a trend for increase in strength performance and reduce in cholesterol level when combined with resistance training.

영유아 성장발달 스크리닝 프로그램의 개발 및 운영결과 분석

박인숙 ( In Sook Park ) 부모자녀건강학회 2008 부모자녀건강학회지 Vol.11 No.1

This is an underlying study for expanding child growth and developmental screening program, which had been implemented as a part of maternal child health service in a certain public health center located in P City. This study attempted to develop system model to discover, consult and follow-up developmental disabilities in children in early stage. For the purpose of providing groundwork for further development of screening program, the system model was analyzed and evaluated. One of the focuses of this study was developing practical tool that can aid small number staffs of public health center to handle large number of patients. 9 types of developmental checklist by key month was developed to support understaffed public health center. These checklists were also supplied to other public health centers, greatly improving qualitative and quantitative development of screening project. Also, the 4-step program of operating and managing child growth and developmental screening was proved to be quite effective. Total 632 children were evaluated and 21 of them were suspected to have developmental problem. Among these children, 8 children were determined to receive regular supervision of public health center. Other 13 children were recommended to visit professional institution, but only 7 of them actually visited institution. Four of these children who visited professional institution are currently receiving treatment, while the other 3 children were determined to require close observation. Five times of screening education were provided to the staffs in public health center and personnel in charge of children in every district public center in P City. The purpose of this training was to improve individuals` capability to implement project and to establish basis for expanding child growth and developmental screening program. The participants were guided to have continuous attention for the project, and their knowledge, skill and recognition were greatly improved through educational training. Also, professional child consulting and education, including lecture for baby food and baby food menu exhibition, were given to parents. Through this opportunity, parents acquired higher understanding about baby food while the local residents` recognition for maternal child health service was greatly improved.