다파장 라만 라이다 관측을 통한 황사의 이동 고도 분포에 따른 광학적 특성 변화 규명

신성균 ( Sung Kyun Shin ),박영산 ( Young San Park ),최병철 ( Byoung Choel Choi ),이권호 ( Kwon Ho Lee ),신동호 ( Dong Ho Shin ),김영준 ( Young J Kim ),노영민 ( Young Min Noh ) 대한원격탐사학회 2014 大韓遠隔探査學會誌 Vol.30 No.5

광주과학기술원의 다파장 라만 라이다를 이용한 에어로졸 연속관측이 2009년부터 2011년까지 3년간 수행되었다. 장기 연속 관측을 통해 얻어진 라이다 신호들의 분석을 통해 편광소멸도를 산출해 내었고, 편광소멸도를 통하여 황사 층을 구분해 내었다. 구분된 황사의 층의 광학적 특징들이 관측 고도에 따라 다르다는 것을 신호의 분석으로부터 밝혀졌다. 이러한 광학적 특징의 차이를 규명하기 위하여, HYSPLIT 모델을 이용하여 각각 관측된 황사 층들의 유입 경로와 이동 중 고도를 분석하였다. 이러한 황사의 관측 고도에 따른 광학적 특성의 변화는 황사가 장거리 이동 중 통과한 오염물질 발생 지역에서 발생한 오염물질과의 혼합으로부터 기인한 것으로 사료된다. 특히 오염물질 발생 지역을 지날 때의 황사 층의 고도는 황사의 광학적 특성 변화에 가장 큰 영향을 미치는 것으로 판단된다. 3년간 라이다 관측 시스템으로 관측한 황사 중, 중국 산업지역 및 인구밀집도가 높은 지역 등과 같은 인위적 기원의 오염물질 발생 지역을 통과할 때의 고도가 1km 이하 일 때, 0.12 ± 0.01의 낮은 편광소멸도, 355 nm와 532 nm 파장에서 각각 67 ± 9 sr, 68 ± 9 sr 의 낮은 라이다비, 1.05 ± 0.57의 낮은 옹스트롬 지수(Angstrom expon) 보였으며, 이는 오염물질이 갖는 광학적 특성 값과 유사하다. 이와 반면 황사가 3 km 이상의 높은 고도로 오염물질 발생 지역을 통과한 경우는 0.21±0.09의 편광소멸도, 355 nm와 532 nm 파장에서 각각 48 ± 5 sr, 46 ± 4 sr 의 라이다 비, 0.57 ± 0.24 의 옹스토롬 지수를 보이며 이는 순수황사의 광학적 특성과 유사하다. 이는 황사가 중국 오염물질 발생지역을 통과할 때의 고도가 혼합상태의 황사 전체의 광학적 특성에 큰 영향을 미치는 것으로 판단되며, 낮은 고도에서는 오염물질과의 혼합의 정도가 증가하여, 오염물질의 광학적 특성이 우세하게 나타나는 반면, 높은 고도에서는 오염물질과 황사의 혼합이 상대적으로 적게 일어난다고 사료된다. The continuous observations for atmospheric aerosols were conducted during 3 years (2009 to 2011) by using Gwangju Institute of Science and Technology (GIST) multi-wavelength Raman lidar at Gwangju, Korea (35.10°N, 126.53°E). The aerosol depolarization ratios calculated from lidar data were used to identify the Asian dust layer. The optical properties of Asian dust layer were different according to its vertical distribution. In order to investigate the difference between the optical properties of each individual dust layers, the transport pathway and the transport altitude of Asian dust were analyzed by Hybrid Single Particle Lagrangian Integrated Trajectory (HYSPLIT) model. We consider that the variation of optical properties were influenced not only their transport pathway but also their transport height when it passed over anthropogenic pollution source regions in China. The lower particle depolarization ratio values of 0.12 ± 0.01, higher lidar ratio of 67 ± 9 sr and 68 ± 9 sr at 355 nm and 532 nm, respectively, and higher Angstrom exponent of 1.05 ± 0.57 which are considered as the optical properties of pollution were found. In contrast with this, the higher particle depolarization ratio values of 0.21 ± 0.09, lower lidar ratio of 48 ± 5 sr and 46 ± 4 sr at 355 nm and 532 nm, respectively, and lower Angstrom exponent of 0.57 ± 0.24 which are considered as the optical properties of dust were found. We found that the degree of mixing of anthropogenic pollutant aerosols in mixed Asian dust govern the variation of optical properties of Asian dust and it depends on their altitude when it passed over the polluted regions over China.

방사선 조사 후 매식한 임프란트의 표면 종류와 스테로이드 관주에 따른 골 치유 효과에 대한 조직 형태학적 연구

신성수(Sung-Soo Shin),박양호(Yang-Ho Park),박준우(Jun-Woo Park),이건주(Gun-Joo Rhee),김현만(Hyun-Man Kim),고재승(Jae-Seung Ko) 대한구강악안면외과학회 2004 대한구강악안면외과학회지 Vol.30 No.6

The purpose of this study was to evaluate and compare the influence of Steroid topical irrigation and implant surface on bone healing in the irradiated rabbit tibia. Implant to bone contact surface ratio and the pattern of bone healing around hydroxyapatite(HA) coated implant and pure titanium (Ti) implant which were inserted into the irradiated rabbit tibia were compared. 16 Korean house mature male rabbits were used as experimental animal. Each rabbit received 15 Gy of irradiation. 4 weeks after the irradiation, two holes were prepared in the irradiated tibia of each rabbits, where two surface type of implants were inserted :1) HA coated type and 2) pure Ti type. Right before placing implants, one group of rabbit received steroid irrigation and the other group did saline. After the irrigation, two implants of HA coated type and pure Ti type were inserted into the tibia of each rabbits. Each rabbit were sacrificed at 2nd, 4th, and 8th week after the implantation and the specimens were observed by the light microscope. The pattern of bone healing and histomorphometric analysis of the implant-bone interface were done. The results were as follows. 1. All implants inserted into the irradiated tibia of rabbit did not show any sign of clinical mobility and the bone around implants inserted into the irradiated tibia of rabbit did not show any resorption. 2. The bone to implant contact surface ratio around HA coated implants that received steroid irrigation got more bone to implant contact surface ratio than that of the saline irrigation. This result showed statistically significant(p<0.05). There was no statistically significant difference in 8th week group. 3. Though there was no statistically significant difference HA coated implants had more bone to implant contact surface ratio than pure Ti implant in 2nd and 4th groups, and there was no difference in 8th week group. 4. All implants inserted into the irradiated tibia of rabbit had exhibited successful osseointegraion.

직장암에 대한 수술 전 동시병용 방사선-항암 화학요법

신성수(Seong Soo Shin),안용찬(Yong Chan Ahn),전호경(Ho Kyung Chun,이우용(WooYong Lee),강원기(Won Ki Kang),박영석(Young Suk Park),박준오(Joon Oh Park),송상용(Sang Yong Song),임도훈(Do Hoon Lim, 박원(Won Park),이정은(Jung Eun Lee),강민규 대한방사선종양학회 2003 Radiation Oncology Journal Vol.21 No.2

목 적: 수술 전 동시병용 방사선-항암 화학 요법의 초기 치료성적과 급성 부작용에 대해 알아보고자 하였다. 대상 및 방법: 1999년 6월부터 2002년 4월까지 T3 또는 T4 병기의 직장암으로 진단 받고 완전절제가 어렵거나, 종양이 하부직장에 위치하여 수술 시 항문 괄약근의 보존이 불가능하리라고 예견된 40명의 환자에게 수술 전 동시병용 방사선-항암 화학요법을 적용하여 37명의 환자가 수술전 치료방침을 완료하였다.방사선치료는 전 골반부에 일일 1.8 Gy씩 5주간에45 Gy를 엎드린 자세로 조사하였다. 항암 화학요법은 경구 UFT와 Leucovorin(LV)(12명),정주 5-fluorouracil(FU)와 LV (10명), 정주 5-FU 단독요법(일시 정주 10명, 지속 정주5명)을 각각 시행하였다. 수술은 수술 전 치료 종료후 4˜6주경에 예정하였으며 35명에 대해서 수술을 시도하였다. 결 과: 본 연구의 수술 전 방사선-항암 화학요법에 대한 순응도는 매우 높았다(92.5%, 37/40). 수술 전에 간과폐에 새로운 원격전이가 확인된 2명을 제외한 35명의 환자에서 절제수술을 시도하였고, 22명(62.9%)에서 항문괄약근의 보존이 가능하였으나, 2명(5.7%)은 개복 후 절제수술을 포기하였다. 절제수술을 시행한 33명 중 30명은 육안적 완전절제를, 1명은 육안적 불완전절제를 시행하였으며 2명은 병리소견에 관한 정보를 얻을 수 없었다. 수술 및 병리소견에 근거한 병기하강률은 45.5% (15/33), 절제연 음성 완전절제율은 78.8% (26/33)였다.수술전 방사선치료 도중 급성부작용으로 Grade 3˜4 호중구 감소가 4명(10.8%)에서 발생하였다.절제수술 후 국소재발이 12.1%(4/33), 수술 전 치료방침 완료 후 원격전이는 21.6% (8/37)에서 각각 나타났으며, 3년 생존율은 87%였다. 결 론: 직장암에 대한 수술전 동시병용 방사선-항암 화학요법은 낮은 부작용으로 높은 수술절제율,병기하강률,완전절제율, 항문 괄약근 보존율 등을 얻을 수 있는 효과적인 방법으로 판단되며 앞으로 장기간에 걸친 추적관찰을 요한다. Purpose: To report the early results of preopeartive concurrent radio-chemotherapy (CRCT) for treating rectal cancer. Materials and Methods: From June 1999 to April 2002, 40 rectal cancer patients who either had lesions with a questionable resectability or were candidates for sphincter-sacrificing surgery receivedpreoperative CRCT. Thirty-sevenpatients completed the planned CRCT course. 45 Gy by 1.8 Gy daily fraction over 5 weeks was delivered to the whole pelvis in the prone position. The chemotherapy regimens were oral UFT plus oral leucovorin (LV) in 12 patients, intravenous bolus 5-FU plus LV in 10 patients, and intravenous 5-FU alone in 15 patients (bolus infusion in 10, continuous infusion in 5). Surgery was planned in 4˜6 weeks of the completion of the preoperative CRCT course, and surgery was attempted in 35 patients. Results: The compliance to the current preoperative CRCT protocol was excellent, where 92.5% (37/40) completed the planned treatment. Among 35 patients, in whom surgery was attempted after excluding two patients with new metastatic lesions in the liver and the lung, sphincter-preservation was achieved in 22 patients (62.9%), while resection was abandoned during laparotomy in twopatients (5.7%). Gross complete resection was performed in 30 patients, gross incomplete resection was performed in one patient, and no detailed information on the extent of surgery was available in two patients. Based on the surgical and pathological findings, the down-staging rate was 45.5% (15/33), and the complete resection rate with the negative resection margin 78.8% (26/33). During the CRCT course, grade 3˜4 neutropenia developed in four patients (10.8%). Local recurrence after surgical resection developed in 12.1% (4/33), and distant metastases after the preoperative CRCT start developed in 21.6% (8/37). The overall 3-years survival rate was 87%. Conclusion: Preoperative CRCT in locally advanced rectal cancer is well tolerated and can lead to high resection rate, down-staging rate, sphincter preservation rate, however, longer term follow-up will be necessary to confirm these results.

직장암에 대한 수술 전 동시병용 방사선-항암 화학요법: 초기 치료결과 보고

신성수,안용찬,전호경,이우용,강원기,박영석,박준오,송상용,임도훈,박원,이정은,강민규,박영제,Shin, Seong-Soo,Ahn, Yong-Chan,Chun, Ho-Kyung,Lee, Woo-Yong,Kang, Won-Ki,Park, Young-Suk,Park, Joon-Oh,Song, Sang-Yong,Lim-Do-Hoon,Park, Won,Lee, Jun 대한방사선종양학회 2003 Radiation Oncology Journal Vol.21 No.2

목적: 수술 전 동시병용 방사선-항암 화학 요법의 초기 치료성적과 급성 부작용에 대해 알아보고자 하였다. 대상 및 방법: 1999년 6월부터 2002년 4월까지 T3또는 T4 병기의 직장암으로 진단 받고 완전절제가 어렵거나, 종양이 하부직장에 위치하여 수술 시 항문 괄약근의 보존이 불가능하리라고 예견된 40명의 환자에게 수술 전 동시병용 방사선-항암 화학요법을 적용하여 37명의 환자가 수술 전 치료방침을 완료하였다. 방사선치료는 전 골반부에 일일 1.8 Gy씩 5주간에 45 Gy를 엎드린 자세로 조사하였다. 항암 화학요법은 경구 UFT와 Leucovorin (LV)(12명), 정주 5-fluorouracil (FU)와 LV (10명), 정주 5-FU 단독요법(일시 정주 10명, 지속 정주 5명)을 각각 시행하였다. 수술은 수술 전 치료 종료 후 4$\~$6주경에 예정하였으며 35명에 대해서 수술을 시도하였다. 결과: 본 연구의 수술 전 방사선-항암 화학요법에 대한 순응도는 매우 높았. (92.5$\%$, 37/40). 수술 전에 간과 폐에 새로운 원격전이가 확인된 2명을 제외한 35명의 환자에서 절제수술을 시도하였고, 22명(62.9$\%$)에서 항문 괄약근의 보존이 가능하였으나, 2명(5.7$\%$)은 개복 후 절제수술을 포기하였다. 절제수술을 시행한 33명 중 30명은 육안적 완전절제를, 1명은 육안적 불완전절제를 시행하였으며 2명은 병리소견에 관한 정보를 얻을 수 없었다. 수술 및 병리소견에 근거한 병기하강률은 45.5$\%$ (15/33), 절제연 음성 완전절제율은 78.8$\%$ (26/33)였다. 수술 전 방사선치료 도중 급성 부작용으로 Grade 3$\~$4 호중구 감소가 4명(10.8$\%$)에서 발생하였다. 절제수술 후 국소 재발이 12.1$\%$ (4/33), 수술 전 치료방침 완료 후 원격 전이는 21.6$\%$ (8/37)에서 각각 나타났으며, 3년 생존율은 87$\%$였다. 결론: 직장암에 대한 수술 전 동시병용 방사선-항암 화학요법은 낮은 부작용으로 높은 수술절제율, 병기하강률, 완전절제율, 항문 괄약근 보존율 등을 얻을 수 있는 효과적인 방법으로 판단되며 앞으로 장기간에 걸친 추적관찰을 요한다. Purpose: To report the early results of preopeartive concurrent radio-chemotherapy (CRCT) for treating rectal cancer. Materials and Methods: From June 1999 to April 2002, 40 rectal cancer patients who either had lesions with a questionable resectability or were candidates for sphincter-sacrificing surgery received preoperative CRCT. Thirty-seven patients completed the planned CRCT course. 45 Gy by 1.8 Gy daily fraction over 5 weeks was delivered to the whole pelvis in the prone position. The chemotherapy regimens were oral UFT plus oral leucovorin (LV) in 12 patients, intravenous bolus 5-FU plus LV in 10 patients, and intravenous 5-FU alone in 15 patients (bolus infusion in 10, continuous infusion in 5). Surgery was planned in 4$\~$6 weeks of the completion of the preoperative CRCT course, and surgery was attempted in 35 patients. Results: The compliance to the current preoperative CRCT protocol was excellent, where 92.5$\%$ (37/40) completed the planned treatment. Among 35 patients, in whom surgery was attempted after excluding two patients with new metastatic lesions in the liver and the lung, sphincter-preservation was achieved in 22 patients (62.9$\%$), while resection was abandoned during laparotomy in two patients (5.7$\%$). Gross complete resection was peformed in 30 patients, gross incomplete resection was peformed in one patient, and no detailed information on the extent of surgery was available in two patients. Based on the surgical and pathological findings, the down-staging rate was 45.5$\%$ (15/33), and the complete resection rate with the negative resection margin 78.8$\%$ (26/33). During the CRCT course, grade 3 $\~$4 neutropenia developed in four patients (10.8$\%$). Local recurrence after surgical resection developed in 12.1$\%$ (4/33), and distant metastases after the preoperative CRCT start developed in 21.6$\%$ (8/37). The overall 3-years survival rate was 87$\%$. Conclusion: Preoperative CRCT in locally advanced rectal cancer is well tolerated and can lead to high resection rate, down-staging rate, sphincter preservation rate, however, longer term follow-up will be necessary to confirm these results.

분무성형법에 의한 고강도 , 고전도도 Cu 계 합금의 합금개발과 공정개발 연구 (1)

정철민(Cheol Min Jeong),박신성(Shin Sung Park),정은(Eun Jung) 대한금속재료학회 1991 분말야금 Vol.3 No.-

측두하악관절 장애에 대한 임상진단의 유효성 연구

김형욱(Hyung Wook Kim),신성수(Sung-Soo Shin),김종식(Jong-Sik Kim),김기영(Ki-Young Kim),김윤지(Yoon-Ji Kim),홍순민(Soon-Min Hong),천세환(Se-Hwan Cheon),박양호(Yang-Ho Park),최원철(Won-Cheul Choi),박준우(Jun-Woo Park) 대한구강악안면외과학회 2007 대한구강악안면외과학회지 Vol.33 No.4

Purpose: The diagnostic relevancies and characteristics and of clinical methods in the diagnosis of internal derangement (ID) were tested by comparing the results of them with those of magnetic resonance imaging (MRI). Methods: 75 patients (150 temporomandibular joints; TMJs), who were suspected to have ID by clinical diagnoses, were included. Clinical diagnoses including mouth opening pathway and TMJ sound were conducted and MRI takings were done. Accuracies, sensitivities, specificities, positive predictive values, and negative predictive values of clinical diagnosis, mouth opening pathway, and TMJ sound were calculated by comparing with diagnoses with MRIs. Results: Accuracy, sensitivity, specificity, positive predictive value, and negative predictive value of clinical diagnosis were 59.3%, 83%, 49%, 81%, and 51%. They were 59%, 82%, 25%, 73%, and 35% for mouth opening pathways. Although deviation was somewhat accurate for representing disc displacement with reduction (ADDWR), other discrepancies on opening pathways were not clinically relevant. Accuracy, sensitivity, specificity, positive predictive value, and negative predictive value of clicking sounds were 85%, 49%, 78%, 85%, and 37%. TMJs with crepitus were only three. But all TMJs with crepitus were diagnosed to have disc displacement without reduction (ADDWOR). Conclusion: When compared with diagnoses with MRIs, clinical diagnoses for ID were not so accurate. But they were suitable for screening tests for ID. Opening pathways and TMJ sounds were not so relevant in the diagnoses of IDs and so it was concluded that considerations for other factors must be included in the diagnoses of IDs.

단방성 법랑아세포종의 보존적 수술에 관한 증례보고 및 문헌고찰

신민영(Min-Young Shin),이혁기(Hyuk-Kee Lee),최제원(Je-Won Choi),신성수(Sung-Soo Shin),박양호(Yang-Ho Park),박준우(Jun-Woo Park) 대한구강악안면외과학회 2005 대한구강악안면외과학회지 Vol.31 No.1

An Ameloblastoma is one of the most common odontogenic tumors. The treatment of ameloblastoma has been controversial because of this disease entity as a slow-growing, locally invasive tumor with high rate of recurrence. Recurrence rate of ameloblastoma are reported 15% to 25% after radical treatment and 75% to 90% after conservative treatment. On the other hand, Robinson and Gardner reported that the recurrence rate after conservative treatment of unicystic ameloblastoma was lower than those of multicystic or solid lesion. In this report, what we want to show is to review the articles to find out pros and cons of conservative treatment of ameloblastoma. In addition we would like to discuss which requies conservative treatment or radical treatment are more acceptable through our case report.

하악골 결손환자에서 수평적 골 신장술과 임프란트 보철수복 : 증례보고

신민영(Min-Young Shin),안준현(Jun-Hyun An),한정환(Jung-Hwan Han),신성수(Sung-Soo Shin),박양호(Yang-Ho Park),박영주(Young-Ju Park),박준우(Jun-Woo Park,이건주(Gun-Joo Rhee) 대한구강악안면외과학회 2003 대한구강악안면외과학회지 Vol.29 No.6

Distraction osteogenesis is a biologic process in which new bone is formed between bone fragments being separated by a tractional force. This technique has the advantage of initiating new bone growth without bone transplantation and promoting the growth of soft tissue. Mandibular distraction osteogenesis has shown to be effective to treat congenital or acquired mandibular hypoplasias. On the basis of positive results with implant-supported prostheses, the use of implants in the distracted site can significantly help stabilize the prosthesis. We obtained good result in the patient with mandibular deficiency due to trauma, who have been reconstructed with distraction osteogenesis and implant. We report our experiences with literature view.

간장 ( 肝臟 ) 및 담도 ( 膽道 ) : 심한 재발성 간염을 일으킨 만성 B형 간염 환자에서의 인터페론의 치료효과

유재영(Jae Young Yoo),박충기(Choong Kee Park),김학양(Hak Yang Kim),임규성(Kyu Sung Lim),송숙희(Sook Hee Song),김규태(Kyu Tae Kim),박승욱(Seung Wook Park),조호준(Ho Jun Cho),김종혁(Jong Hyeok Kim),박신성(Shin Sung Park),김동준(Dong Ju 대한소화기학회 1991 대한소화기학회지 Vol.23 No.2

N/A We treated nine patients with chronic hepatitis B with recombinant interferon alpha who showed severe exacerbation of hepatitis activity. All had HBsAg for at least 5 years, and had multiple episodes of elevated serum transaminase levels. They were all men, ages 26~55 (mean 41) years. The range of serum AST was 131~885 (mean 326) U/L, the ALT 62~610 (mean 303) U/L, the bilirubin 1.3~37.3 (mean 12.0) mg/dl, total protein 4.4~8.7 (mean 6.6) g/dl, and the albumin 2.4~4.4 (mean 3, 1) g/dl. Seven patients had ascites by ultrasonogram and three showed clinical evidence of grade I hepatic encephalopathy. The needle biopsy of the liver was avalilable in 6 patients, and showed severe chronic active hepatitis with established macronodular cirrhosis. Interferon was administered in a dose of three million units subcutaneously every other day for 6 months and followed up for 12 to 24 months. The results were as follows: 1) Serum transaminases: The serum transaminases became normal in 8 patients during therapy but incresed again during the follow-up in two. One patient, whose transaminses decreased temporalily with therapy, died at the 45th days of therapy due to hepatic failure. 2) Serum bilirubin: In 7 patients with hyperbilirubinemia (2.4~37.3mg/dl), the bilirubin became normal in 5 during therapy, but incresed again in 2 during the follow up-period. In one dead case, the elevated bilirubin decreased transiently but increased again during treatment. 3) Serum albumin: In 4 patients with hypoalbuminemia, the serum albumin became normal in two, and in one became transiently elevated but decreased again during treatment. 4) Prothrombin time: In 6 patients whose prothrornbin time was prolonged, it became normal in 5 except in one patient who died. 5) Ascites: In 7 patients with ascites, the ascites disappeared in 3 during the treatment and in 3 during the follow-up period. But the ascites developed again in 2 of 6 patients. There was no change of ascites in an expired case. 6) Serum HBeAg and HBV-DNA: In 7 patients with serum HBeAg and HBV-DNA, these markers became negative in 5 during treatment, but positive again in one patient during the follow-up period. 7) Symptoms of hepatic encephalopathy: Among 3 patients who developed hepatic encephalopathy (Grade 1) before therapy, 2 patients were improved during therapy. In conclusion, this study, although not adequately controlled, suggested that alpha intreferon therapy may be effective and safe in patients with chronic hepatitis B who showed severe exacerbation of disease activity. A prospective controlled study is needed to assess the role of interferon in these patients.

Patterns of Care Study를 위한 2006년 한국 방사선종양학과 전문의들의 전립선암 방사선치료원칙 조사연구

김진희(Jin Hee Kim),김재성(Jae Sung Kim),하성환(Sung Whan Ha),신성수(Seong Soo Shin),박원(Won Park),조재호(Jae Ho Cho),서창옥(Chang Ok Suh),오영택(Young Taek Oh),신세원(Sei Won Shin),김재철(Jae Chul Kim),장지영(Ji Young Jang),남택근(Ta 대한방사선종양학회 2008 Radiation Oncology Journal Vol.26 No.2

목 적: 한국인의 비뇨기암 중 1990년 말부터 발병률이 빠르게 증가되고 있는 전립선암의 치료에 있어 전국 각 병 원의 방사선종양학과에서 시행되고 있는 방사선치료의 현황을 조사, 분석하고 이를 바탕으로 전립선암의 Patterns of care study (PCS) 개발의 기본 자료로 이용하고자 한다. 대상 및 방법: 전국 13개 대학병원의 방사선종양학과 전문의들의 설문조사를 통하여 각 의사들의 전립선암에 대한 치료 현황과 치료원칙을 수집, 분석하였다. 결 과: 진단은 초음파유도 조직생검을 적게는 6개에서 12개 부위, 평균 9개 부위에서 얻고 있으며 진단당시의 영상학적 검사는 대부분에서 자기공명영상과 전신골스캔을 사용하고 있다. 방사선치료를 시행할 때 내부고정물과 외부고정물은 각각 61.5%, 76.9%에서 사용하며 방사선치료의 임상표적부위는 병원마다 다양하게 시행하고 있었다. 전골반 방사선치료는 76.9%에서 45∼50.4 Gy를, 정낭의 방사선치료는 92.3%에서 시행하고 있으나 총방사선량은 54∼73.8 Gy로 다양하였다. 근치적인 방사선치료의 방사선량은 저위험군에서 고위험군으로 갈수록 증가하였으나 병원간의 차이가 60∼78.5 Gy로 넓었다. 세기조절 방사선치료를 시행하는 병원은 53.8%로 반 수 이상에서 시행하고 있으며 총방사선량은 70 Gy이상 이었다. 동시추가분할선량법(SIB; simultaneous integrated boost)을 시행하는 병원은 3곳으로 표적부피와 방사선량이 다양하였다. 전립선 전적출술 후 생화학적 재발의 경우 84.6%의 병원에서 방사선치료를 시행하고 있으며 방사선치료 조사야는 전골반와부터 전립선부위까지 다양하며 총방사선량도 다양하였다. 결 론: 전국 13개 병원의 전립선암의 방사선 치료현황을 볼 때 계속 증가하는 전립선암에 대한 전국병원의 방사선치료의 patterns of care study가 필요하며 이를 토대로 전립선암 방사선치료의 guideline을 제시할 필요가 있겠다. Purpose: To conduct a nationwide academic hospital patterns of the practice status and principles of radiotherapy for prostate cancer. The survey will help develop the framework of a database of Korean in Patterns of Case Study. Materials and Methods: A questionnaire about radiation treatment status and principles was sent to radiation oncologists in charge of prostate cancer treatment at thirteen academic hospitals in Korea. The data was analyzed to find treatment principles among the radiation oncologists when treating prostate cancer. Results: The number of patients with prostate cancer and treated with radiation ranged from 60 to 150 per academic hospital in Seoul City and 10 to 15 outside of Seoul City in 2006. The primary diagnostic methods of prostate cancer included the ultrasound guided biopsy on 6 to 12 prostate sites (mean=9), followed by magnetic resonance imaging and a whole body bone scan. Internal and external immobilizations were used in 61.5% and 76.9%, respectively, with diverse radiation targets. Whole pelvis radiation therapy (dose ranging from 45.0 to 50.4 Gy) was performed in 76.9%, followed by the irradiation of seminal vesicles (54.0∼73.8 Gy) in 92.3%. The definitive radiotherapy doses were increased as a function of risk group, but the range of radiation doses was wide (60.0 to 78.5 Gy). Intensity modulated radiation therapy using doses greater than 70 Gy, were performed in 53.8% of academic hospitals. In addition, the simultaneous intra-factional boost (SIB) technique was used in three hospitals; however, the target volume and radiation dose were diverse. Radiation therapy to biochemical recurrence after a radical prostatectomy was performed in 84.6%; however, the radiation dose was variable and the radiation field ranged from whole pelvis to prostate bed. Conclusion: The results of this study suggest that a nationwide Korean Patterns of Care Study is necessary for the recommendation of radiation therapy guidelines of prostate cancer.