β2-microglobulin의 복막이동 특성 및 복막 청소율에 관한연구

문지현,김대중,오하영,이숭구,이방훈,채영숙,김범,오동진,허우성,김윤구,강우헌 대한신장학회 1999 Kidney Research and Clinical Practice Vol.18 No.4

In addition to CAPD, various modalities of peritoneal dialysis such as CCPD and NIPD have been introduced recently. The adequacy in these peritoneal dialysis has been evaluated by clearance of small molecular weight solutes such as creatinine(molecular weight 113 Dalton) and urea(molecular weight 60 Dalton). The middle molecular weight solutes(molecular weight 3,000 to 12,000 Dalton) have been regarded as one of the uremic toxins. Relatively larger clearance of middle molecular weight solutes is one of the advantages of CAPD compared with HD. Although peritoneal transport of middle molecular solutes can be different from that of small molecular weight solutes because of its size, there are a few reports about peritoneal transport characteristics and clearance of middle molecular weight solutes in various modalities of PD. We wanted to analyze peritoneal transport characteristics and clearances of middle molecular weight solute in various modalities of peritoneal dialysis in comparison with small molecular weight solutes. To evaluate the potential differences in peritoneal transport characteristics and clearances of middle and small molecules in CAPD, CCPD and NIPD, we compared transport characteristics and clearance of β2-MG and creatinine. 35 CAPD patients, 9 CCPD patients, 7 NIPD patients were included in the study, who were clinically stable for at least one month without peritonitis. he β2-MG concentrations in serum and dialysate as measured by radioimmunoassay. Standard peritoneal equilibration test and a weekly peritoneal clearance for creatinine and β2-microglobulin were used. The results were as follows: 1)Dialysate to plasma ratio of β2-MG were 0.11±0.03, 0.13±0.05, 0.10±0.02, 0.08±0.03, respectively in high(N=6), high average(N=13), low average(N= 14), low(N=7) group according to PET. There were significant differences between high average and low average, high average and low group(p$lt;0.05). Correlation between D/Pβ2-MG ratio and D/Pcr ratio was significant(spearman's p=0.453, p$lt;0.05). 2)Ipatients, peritoneal creatinine and β2-MG clearance were 48.9, 8.2L/wk, respectively and there was a weak correlation between them (Spearman's p=0.294, p$lt;0.05). 3)The peritoneal creatinine clearance were 48.9, 41.0, 35.9L/wk and ?2-MG clearance were 8.2, 5.5, 4.1L/wk, respectively in CAPD, CCPD and NIPD. The ratio of peritoneal β2-MG clearance to creatinine clearance were 0.16, 0.14, 0.11, respectively in CAPD, CCPD and NIPD. Peritoneal β2-MG clearance in APD such as CCPD and NIPD is lesser than that in CAPD. In conclusion, peritoneal transport characteristics for β2-MG differ from that for creatinine, although peritoneal clearnce for β2-MG corrleated with that for creatinine. Perioneal clearance for β2-MG was better in CAPD than in APD.

다양한 방법을 이용한 수부 연부 조직 결손의 재건

문지현,박병화,이내호,양경무 의과학연구소 1998 全北醫大論文集 Vol.22 No.2

저자들은 1996넌 2월부터 1998년 3월까지 수부연부조직결손 환자 58례에 대하여 VY 전진피판술, 지방근막반전피판술, 수배부 중수골동맥 역행성 도서형피판술, 동측 수지부 역혈행성 도서형피판술, 원위부 서혜부 피판술과 요골부 전박 유리 피판술 등의 다양한 방법의 피판술을 시행하여 좋은 결과를 얻었으며 수부손상에서 연조직결손의 만족스러운 재건을 위해서는 견고한 연부조직과 수지의 길이유지가 필요할 것으로 사료되었으며, 사용할 때 동통이 없으며 술후내구성과 감각회복 등 기능 및 미용적인 면을 고려하여 술식을 선택하여야 하며, 재건 수술시에도 손상의 정도, 손상 수지의 기대되는 기능적 역할, 환자의 전신상태 및 술후 요구도, 그리고 수술의 장단점 등도 예후를 결정하는 중요인자로 사료되었다.

유리 피판을 이용한 인두식도 결손의 재건

문지현,이내호,양경무,Moon, Ji-Hyun,Lee, Nae-Ho,Yang, Kyung-Moo 대한미세수술학회 1999 Archives of reconstructive microsurgery Vol.8 No.2

저자들은 1990년 12월부터 1999년 2월까지 48례의 경우에서 하인두에 발생한 악성종양을 광범위 절제한 후 유리피판 또는 근피판을 이용하여 재건하였다. 39례에서 유리공장 피판, 5례에서 유리전박 피판을 tubing 형태로 사용했으며, 2례에서는 유리전박 피판을 patch 형태로 사용하였고, 2례에서는 대흉근 근피판을 이용하여 경부식도를 재건하여 다음과 같은 결과를 얻을 수 있었다. 1. 하인두의 악성종양이 고령의 나이에 발생한다는 사실을 감안했을 때 유리전박 피판에 비해 급양공장루를 통해 조기에 영양섭취가 손쉬운 유리공장 피판이 환자의 상태를 정상으로 회복시키는데 장점이 있었다. 2. 술후 가장 흔한 합병증인 누공의 발생은 문합을 제대로 시행했을 경우 우려할 필요 없으며, 따라서 술후에 시행하는 식도조영검사는 누공의 증상이 있는 경우에만 선별적으로 실시해야 할 것이다. 3. 문합부 내경의 협착이 우려될 때는 직경이 큰 비강영양튜부(nasogastric tube)를 조기에 삽입하여 극단적인 협착을 감소시키고, 영양섭취 경로를 확보해야 한다. 4. 문합부 협착을 예방하기 위해 상하부 문합부 모두를 파형으로 도안하여 피판을 문합 봉합해야 하며, 협착이 의심스러울 때는 내시경검사를 시행하여 확진해야 한다. 5. 혈관문합은 유리전박 피판을 시행하는 경우에 있어서 수월하였으며, 유리공장 피판을 시행할 때는 술전에 정맥이식을 고려해야 한다. The laryngopharyngectomy for tumor ablation is the most common indication for pharyngoesophageal reconstruction in our country. Most of these cases are advanced laryngeal cancer that has spread beyond the larynx, pharynx and cervical esophagus. Such patients are obviously unable to breathe, swallow, or speak in the normal manner. The ideal reconstruction would restore normal anatomy, permitting patients to breathe and swallow without aspiration, and would not require a permanent tracheostomy. Reconstruction of the pharyngoesophageal defect traditionally been carried out with tubed local random flap, deltopectoral or musculocutaneous flap. Another approach is the pedicled enteric flap. But microsurgical reconstruction of the pharyngoesophagus, using either the free jejunal or the tubed radial forearm flap, have now become the preferred technique. Among them, we used jejunal free flap in 39 cases, tubed radial forearm free flap in 5 cases, patched radial forearm free flap in 2 cases and pectoralis major myocutaneous island flap in 2 cases from December 1990 to Febrary 1999. In this paper we illustrated that both forearm and jejunal free flap is a usful alternative in reconstruction of hypopharynx and cervical esophagus.

교육용 길원형의 적합성 향상을 위한 외관평가

문지현,전은경 한국의류학회 2010 한국의류학회 학술대회논문집 Vol.2010 No.-

상태 일치를 이용한 연속시간 T-S 퍼지 모델의 추종 제어기 설계

문지현,이호재 제어로봇시스템학회 2015 제어로봇시스템학회 국내학술대회 논문집 Vol.2015 No.5

남녀대학생의 정치의식과 정치참여 태도에 관한 연구

문지현 서울여자대학교 여성연구소 1998 여성연구논총 Vol.13 No.-

지방자치와 여성의 역할

문지현 서울여자대학교 사회과학연구소 1995 사회과학논총 Vol.1 No.-

T—S 퍼지 시스템을 위한 시변 추종제어기의 지능형 디지털 재설계

문지현,송현석,이호재,김도완 제어로봇시스템학회 2012 제어로봇시스템학회 국내학술대회 논문집 Vol.2012 No.4

가네코 미스즈(金子みすゞ) 시 고찰 -보이는 세계와 보이지 않는 세계 중심으로-

문지현 한일일어일문학회 2011 한일어문논집 Vol.15 No.-

Misuzu Kaneko is a nursery rhyme poet. It is easy to feel that it is a thing of "the sake with a child" by all means when I say nursery rhyme. We are easy to be convinced that the object of the song is limited to "a child". However, the thing called the nursery rhyme is over if I fry "a child" as an object letting you sing. The object which is about to appeal for something is not limited by the contents. As for the poetry of Misuzu Kaneko, an animal and the sky, the sea are taken a lot away as a subject. Therefore it is sung by pretty words without sense of incongruity even if emitted from the entrance of the child. The characteristic of the poetry of Misuzu Kaneko whom it delivers for this report is only just a part, but an indefinite narrator becomes the viewpoint, and it is it with an axis, and it is a characteristic of the poetry that what let you develop contents took up by this report. Because I become a narrator, and reader oneself becomes the viewpoint, it is led to the viewpoint of Misuzu without sense of incongruity naturally by it not being identified a narrator. And we can imagine the invisible world that Misuzu Kaneko imagines in the same way. The imagination itself is received as fresh new discovery at the same time to the reader side, and it is thought that it is drawn into the world of Misuzu Kaneko more. And that such a characteristic may be able to be settled as "nursery rhyme poetry" simply may be a reason having doubt toward. Anyone experiences a Misuzu Kaneko original viewpoint and thinks that I may turn to the viewpoint to the various world as a result of this.

"중국분류주제사표(中國分類主題詞表)"의 한.일 관련 주제명에 대한 비교 분석

문지현,김정현,Moon, Ji-Hyun,Kim, Jeong-Hyen 한국도서관정보학회 2011 한국도서관정보학회지 Vol.42 No.3

This study compared and analyzed, after extracting the subject titles related to Korea and Japan from the second version of Chinese Classified Thesaurus, the number of titles and characteristics according to the subjects. The analysis result shows that total number of Korea-related titles including proper nouns was 215, which is limited in comparison to that of Japan, in terms of the number and diversity of the subjects. Particularly, the CCT does not accurately reflect the current state of Korea as it uses the word 'Josun' to denote Korea and calls Korean War 'Josun War' as well as only recording it in North Korean history. Meanwhile, Japan-related subject titles include many that show the complicated historical relationship between Japan and China, such as Manchurian Incident and Japan-China War. 이 연구는 "중국분류주제사표(中國分類主題詞表)" 제2판에 수록된 한국과 일본관련 주제명을 추출하여 주제명의 수와 주제별 특성을 비교 분석한 것이다. 분석 결과, 한국관련 주제명표목은 고유명을 포함하여 총 215개로, 일본관련 주제명표목과 비교하였을 때 주제명 수나 다양성 측면에서 많은 한계를 보여주고 있다. 특히 한국의 국가명칭을 '조선(朝鮮)'으로 표기한 점이나, 한국전쟁을 '조선전쟁'으로 설정하고 북한의 역사에만 수록하는 점 등은 우리나라의 현실과는 상당한 차이를 보여주고 있다. 한편, 일본관련 주제명에는 '만주사변'과 '중일전쟁'과 같이 복잡했던 중 일 양국간의 역사적 관계를 보여주는 주제명이 다수 수록되어 있다.