後鼻漏를 主訴로 한 慢性 副鼻洞炎 患者의 治驗 1例

김창환,선영재,임웅경,김현기,Kim, Chang-hwan,Sun, Young-jae,Lim, Woong-kyoung,Kim, Hyun-gi 대한한방안이비인후피부과학회 2003 한방안이비인후피부과학회지 Vol.16 No.2

Paranasal sinusitis is a common disease in the otorhinolaryngology area. It is the change of inflammation at the mucous membrane which surrounds paranasal sinus. Chronic paranasal sinusitis is a chronic inflammation disease with purulent, mucous rhinorrhea, postnasal drip and cough. The attacked period continues above three months and it repeats exacerbation and remission. We diagnosed and treated an outpatient who complains postnasal drip of chronic paranasal drip of chronic paranasal sinusitis based on the Oriental medical theories and had good result.

단파장 자외선(254nm)에 노출된 고밀도 폴리에틸렌 수지의 카르보닐 지수(CI)와 기계적 물성 변화의 관계에 관한 연구

김창환 ( Chang Hwan Kim ),신진용 ( Jin Yong Shin ) 한국공업화학회 2013 공업화학 Vol.24 No.2

This paper studied the possibility to predict a mechanical property variation from changes in created carbonyl bands by irradiating the surface of high-density polyethylene with short-wavelength ultraviolet radiation of 254nm to induce a fast chemical degradation. The meaning of this study lies in checking whether a mechanical property change with the same chemical property as the induced optical deterioration is caused by using a UVC lamp with high photon energy instead of optical deterioration via xenon arc light source and outdoor exposure test via natural sunlight requiring a long time. The mechanical strength of high-density polyethylene checked by a tensile test and a creep destruction test showed a similar tendency with CI changes. In particular, the yield strength and elongation had a close relationship with the exposure time to ultraviolet radiation. Accordingly, this paper presented a method to grasp the mechanical property change outdoors requiring a long time more fast through the relationship between the mechanical property change and the carbonyl index using a UVC lamp causing the fast surface degradation.

안면신경마비에 대한 안륜근 미소안면침 증례보고

조아름,김지현,주경옥,원재선,김창환,Cho, Ah-Reum,Kim, Ji-Hyun,Chou, Ching-Yu,Won, Jae-Sun,Kim, Chang-Hwan 대한한방안이비인후피부과학회 2010 한방안이비인후피부과학회지 Vol.23 No.2

Objective : This study was designed to evaluate the effect of Miso Facial Acupuncture on Orbicularis Oculi muscle. Methods : Two men and four women with Facial nerve palsy were recruited. Miso Facial Acupuncture on Orbicularis Oculi muscle was performed two times a week for three weeks. The effects of the treatment were evaluated by H-B scale, Y-system and clinical symptom. Results : Before treatment with Miso Facial Acupuncture, three patients showed H-B scale improvement and the other three patients had no change. and four patients showed Y-system improvement and the other two patients had no change. In six cases, the patients had improvement in clinical symptom related with Orbicularis Oculi muscle function. Conclusion : Miso Facial Acupuncture on Orbicularis Oculi muscle showed significant improvement in facial nerve palsy.

Antitumor effects of recombinant human interferon α-2a and hydroxyurea against chronic myelogenous leukemia

김창환,이범준,박종환,박재학,Kim, Chang-hwan,Lee, Beom-jun,Park, Jong-hwan,Park, Jae-hak The Korean Society of Veterinary Science 2000 大韓獸醫學會誌 Vol.40 No.1

Prior to a clinical trial, the in vitro and in vivo antitumor effects of a new recombinant human interferon ${\alpha}-2a$ (rHu/IFN ${\alpha}-2a$) with/without hydroxyurea (HU) were investigated using chronic myelogenous leukemia (CML)-derived cell lines (K562 and KU812F) and BALB/c nude. mice transplanted with KU812F cells. The rHu/IFN ${\alpha}-2a$ ($10^4-10^6IU/ml$) strongly inhibited proliferation of both cell lines and the combined treatments with HU ($10{\mu}g/ml$) were more effective. In nude mice transplanted with KU812F cells. rHu/IFN ${\alpha}-2a(1{\times}10^6IU$) inhibited tumor growth by 42-65% at 15-21 days post-transplantation (DPT). The combined treatment of rHu/IFN ${\alpha}-2a (5{\times}10^5IU$) with HU (0.25mg/g b.w.) inhibited the tumor growth by 48-67% at 12-21 DPT. In addition, the treatment of rHu/IFN ${\alpha}-2a$ ($5{\times}10^6IU\;or\;1{\times}10^7IU$) rejected tumor transplantation by 40%. These results suggest that the new rHU/IFN ${\alpha}-2a$ alone or with HU is effective on CML cell lines.

동해 울릉분지 북동부지역의 지구물리학적 특성 및 지구조 연구

김창환,박찬홍,Kim, Chang-Hwan,Park, Chan-Hong 대한자원환경지질학회 2010 자원환경지질 Vol.43 No.6

본 연구에서는 울릉분지 북동부지역에서 획득한 중력, 자력, 수심자료 등 지구물리자료를 이용하여 이 지역의 지구물리학적 특성 및 지구조를 고찰하고자 하였다. 각각의 자료는 조사기간 및 사용 장비의 차이로 인하여 자료간의 오차가 나타나는데 상대적인 보정을 실시한 후 통합하였다. 울릉분지 북동부에 위치한 연구지역은 울릉도와 독도해산들, 그리고 한국해저간극으로 이루어져 있으며 최대수섬은 약 -2500 m를 보인다. 후리에어이상는 지형의 영향을 잘 반영하며 전체적으로는 울릉도와 독도 및 해산들에서 높은 값을 보인다. 부게이상은 해산들에 의한 국지적인 이상치를 보이지만 한국해저간극 및 울릉분지를 중심으로 고이상을 보이는데 이는 맨틀상승에 의한 영향이라 판단된다. 자기이상도를 살펴보면 화산체(섬과 해산들)들을 중심으로 복잡한 자기이상대를 나탄낸다. 연구지역 부게중력이상의 파워스펙트럼 분석으로부터 계산된 연구지역 모호면의 평균 깊이는 -16.1 km로 나타났다. 이 파워스펙트럼 분석을 이용하여 모호면 심도 역산을 수행하였다. 이 역산법으로 계산된 모호면의 심도는 한국해저간극지역에서 -16~17 km 정도이며 오끼뱅크 및 울릉도의 북서부쪽으로 갈수록 심도가 깊어지는 결과가 나타났다. 이 역산결과는 울릉분지의 해양지 각이 일반적인 해양지각에 비해 두껍다는 기존 결과와 일치한다. 2차원 중력 모델링 결과에서도 모호면의 심도가 해저면지진계 탐사측선이 지나가는 안용복해산과 독도 사이의 한국해저간극지역에서 얕은 것을 볼 수 있으며 오끼뱅크쪽으로 갈수록 깊어진다. 자화분포도에서는 울릉도와 독도 등 화산체에 의한 강한 자기이상대에 의해 나타나는 자화 분포대를 제외하면 주로 북동-남서방향의 선형배열이 나타난다. 섬도역산 결과, 2차원 중력모델링 및 자화분포 결과를 종합해보면 동해의 생성사 울릉분지의 가능성 있는 spreading center(해저면 확장중심) 위치가 한국해저간극에서부터 울릉분지까지 북동-남서 방향일 것이라는 기존 논문들의 주장과 부합된다고 판단된다. The geophysical characteristics and geological structure of the northeastern part of the Ulleung Basin were investigated from interpretation of geophysical data including gravity, magnetic, bathymetry data, and seismic data. Relative correction was applied to reduce errors between sets of gravity and magnetic data, obtained at different times and by different equipments. The northeastern margin of the Ulleung Basin is characterized by complicated morphology consisting of volcanic islands (Ulleungdo and Dokdo), the Dokdo seamounts, and a deep pathway (Korea Gap) with the maximum depth of -2500 m. Free-air anomalies generally reflect the topography effect. There are high anomalies over the volcanic islands and the Dokdo seamounts. Except local anomalous zones of volcanic edifices, the gradual increasing of the Bouguer anomalies from the Oki Bank toward the Ulleung Basin and the Korea Gap is related to higher mantle level and denser crust in the central of the Ulleung Basin. Complicated magnetic anomalies in the study area occur over volcanic islands and seamounts. The power spectrum analysis of the Bouguer anomalies indicates that the depth to the averaged Moho discontinuity is -16.1 km. The inversion of the Bouguer anomaly shows that the Moho depth under the Korea Gap is about -16~17 km and the Moho depths towards the Oki Bank and the northwestern part of Ulleung Island are gradually deeper. The inversion result suggests that the crust of the Ulleung Basin is thicker than normal oceanic crusts. The result of 20 gravity modeling is in good agreement with the results of the power spectrum analysis and the inversion of the Bouguer anomaly. Except the volcanic edifices, the main pattern of magnetization distribution shows lineation in NE-SW. The inversion results, the 2D gravity modeling, and the magnetization distribution support possible NE-SW spreading of the Ulleung Basin proposed by other papers.

독도 화산체 정상부해역의 정밀해저지형 및 지구물리학적 특성 연구

김창환,박찬홍,이명훈,최순영,주형태,Kim, Chang Hwan,Park, Chan Hong,Lee, Myoung Hoon,Choi, Soon Young,Jou, Hyeong Tae 대한자원환경지질학회 2012 자원환경지질 Vol.45 No.6

본 연구는 현재까지 수행된 독도 화산체 정상부 해역의 정밀수심 및 지구물리 조사 자료를 종합하고 분석하여 정상부 해역의 정밀해저지형 및 지구물리학적 특성을 연구하였다. 독도 연안역 동도와 서도 사이 연결 수로는 약 10 m 이내의 얕은 수심을 이루고 있다. 독도 화산체 정상부해역의 전체적인 수심은 동도와 서도의 육지부부터 수면 아래 약 30 m 까지는 불규칙하며 급한 경사면을 가지고, 그 후 수심 약 30 m부터 수심 약 80 m 까지는 경사가 점차 낮아지다가 수심 약 80 m 이하로 완만한 경사를 보이면서 외해역으로 깊어진다. 독도 육지부와 그 북동쪽 및 북서쪽으로 연장되는 암반들은 독도를 생성시킨 화구륜의 잔해로 판단되며 동도와 서도는 화구륜의 남쪽 한부분일 가능성이 큰 것으로 생각된다. 또한 정상부 해역의 해저지형에서는 소규모의 움푹 패인 지형들이 나타나는데 이는 독도 형성 후 나중에 생성된 소규모 분화구의 흔적들로 추정된다. 독도 정상부 해역은 주로 암반이 많이 분포하지만 곳곳에서는 모래 퇴적층들도 나타나는 것을 볼 수 있다. 독도 화산체 정상부에는 계단형의 경사면들이 나타나는데 이는 제4 기에 나타난 해침, 해퇴 등 해수면변화에 의해 만들어진 해저단구로 유추되며, 지역별로 차이가 있기는 하지만 주로 약 30 m, 60 m, 80 m 및 약 100 m의 수심대를 위주로 하여 몇 개의 주요 해저단구가 나타나는 것으로 판단된다. 자기이상도 및 아날니틱신호도를 살펴보면 수면 위 독도에서 연장되는 북동 및 북서쪽의 이상대들은 화구륜의 잔해로 예상되는 암반들의 위치와 유사하게 나타난다. We studied the detailed bathymetry and the geophysical characteristics of the summit of the Dokdo volcano using mutibeam echosounding and geophysical survey data. The bathymetry around the main east and west islets of the Dokdo volcano shows very shallow within about 10 m water depth. From near islets to about 30 m b.s.l., the shallow water area has very steep slope and many irregular sunken rocks. The area from about 30 m to about 80 m b.s.l. shows gentle rises and falls, and less steep slope. The area from 80 m b.s.l. has gradually flat undulation and smooth slope seabaed and is extended to offshore. The main islets of the Dokdo volcano and the rocky sea bottom elongated from the islets might be the residual part of the eroded and collapsed main crater of the Dokdo volcano. The bathymetry and the seafloor image(from backscattering) data show small craters, assumed to be formed by the eruption of later volcanism. The seafloor images propose that, except some areas with shallow sand sedimentary deposits, there are typical rocky bottom such as rocky protrusions and lack of sediments in the main morphology of the survey area. The stepped slopes of the seabed are deduced to be submarine terraces. The several prominent submarine terraces are found at the summit of the Dokdo volcano, suggesting repetition of sea level changes(transgressions and regressions) in the Quaternary. The results of the magnetic anomaly and the analytic signal have a good coherence with other geophysical consequences regarding to the location of the residual crater.

디지털 치의학의 과거와 현재 그리고 미래

김창환,Kim, Chang Hwan 대한심미치과학회 2015 Journal of the Korean Academy of Esthetic Dentistr Vol.24 No.1

치과계에서 캐드캠이 보급되면서 본격적으로 사용한 지 15년이 넘었다. 코핑 정도의 역할에서 구치부 전부관으로 확대되었고, 최근에는 전치부에서도 많이 사용하는 추세이다. 장비의 발전도 비약적이었지만 지르코니아 블록의 발전이 가장 많이 이루어졌다. 개개인의 능력이나 경험 차에 의해 차이는 있을 수 있겠지만, 도재를 올리지 않고 지르코니아에 컬러링만으로도 얼마든지 색을 표현 할 수 있다. 또한 캐드 디자인 만으로도 표면의 질감을 표현하는 것에 우리가 알고 있는 만큼 가능하다. 본 논문에서는 이러한 디지털 치과학의 변천과정을 정리해 보고자 한다. Since its introduction to the dentistry, the CAD/CAM technology has been used over fifteen years. The application of CAD/CAM started from coping fabrication, expanded to the posterior full crown, and anterior restoration manufacture has also become widespread recently. While the development of machine was rapid, the advance of zirconia block was the fastest. Although some differences exist among individuals, the various natural tooth color can be expressed through the zirconia coloring itself without porcelain build up. And the texture characteristics can be reproduced just by CAD design. In this article, the development history of digital dentistry was summarized.

미사일 Fin 액츄에이터용 서보모터의 외란 토크 억제 제어

김창환,Kim, Chang-Hwan 대전대학교 군사연구원 2003 군사학연구 Vol.1 No.-

In this paper, we propose a generalized disturbance torque suppression control scheme of servo motors for missile fin actuators. Our controller consists of both a model based feed-forward controller and a stabilizing feedback controller. The feed-forward controller is designed such that the output of nominal plant tracks perfectly the reference position command with a desired dynamic characteristics. The feedback controller stabilizes the overall closed loop system. Furthermore, the feedback controller contains a free function that can be chosen arbitrary. The free function can be designed so as to achieve both the suppression of disturbances and the robustness to model uncertainties. In order to illuminate the superior performance of our control scheme to the conventional ones, we present some simulation results.

顔面神經麻痺에 대한 臨床 治驗例 보고

김창환,김현기,Kim, Chang-Hwan,Kim, Hyun-Gi 대한한방안이비인후피부과학회 2001 한방안이비인후피부과학회지 Vol.14 No.2

1. Five Clinical tests and case studies show that facial palsy can be improved under the treatment of Acupuncture, Infrared, Electroacupuncture. Herbal medicine and Herbal acupuncture. 2. The most common prodrome appears to be postauricular pain. including headache and dizziness. 3. As the more serious the paralysis becomes. the prodrome gets worse, and the treatment term extends. It also gets harder to perform prognosis 4. We confirm that either physical or mental overwork and stress can be the most likely cause of facial palsy.

腦出血을 동반한 慢性 두드러기 患者의 治驗 1例

김창환,선영재,김현기,Kim, Chang-Hwan,Sun, Young-Jae,Kim, Hyun-Gi 대한한방안이비인후피부과학회 2002 한방안이비인후피부과학회지 Vol.15 No.1

Urticaria is classified as Eunjin in Oriental Medicine. The intrinsic causes include digestive system disorder, food poison, parasite, female reproductive health problem, nervous breakdown, and disorder of endocrine hormone. The extrinsic sources include all kinds of insect bites or stings, medications, pollen, dirt, and toxic smells. Some unknown sources also produce urticaria. The urticaria that lasts for more than six weeks, is categorized as chronic urticaria which is not very different from acute urticaria that occurs rapid but for a short period. The chronic urticaria may come every day, and its symptoms can even get worse at irregular or regular intervals. The cycle is hard to predict. It could be weeks or years. In clinical treatments, the syndromes of patient's chronic urticaria with cerebral hemorrhage have been analyzed and identified as follows: The diagnosis by asking the patient's case history showed that the root cause was retention of food resulting from dysfunction of the spleen and stomach. First, Pyeongwisan was dosed. From the syndrome differentiation with four diagnostic methods, we diagnosed the symptoms as Poong yoel (wind-heat). Then, Hyeongbangpaedocksangamibang was prescribed to get very effective results.