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      • 고려인삼이 흰쥐의 악하선 조직 핵산 함유량에 미치는 영향

        김승훈 최신의학사 1971 最新醫學 Vol.14 No.5

        A study was planned to see if administration of ginseng extract has any influence upon the nucleic acid content of the mandibular gland of rats, and to estimate the effect of ACTH administration upon the nucleic acid content of rats previously primed with ginseng. Ninety male rats (body weight: 150-200 gm) were divided into the ginseng, the saline, and the normal groups, which received for 5 days 0.5 ml /100 gm body weight of ginseng extract solution (4 mg of ginseng alcohol extract in 1 ml of saline), same amount of saline, or no medication, respectively. On the 5th experimental day, each of the 3 groups was further divided into 2 subgroups yielding the ginseng, the ginseng-ACTH, the saline, the saline?ACTH, the normal, and the normal-ACTH subgroups. The ginseng, the saline, and the normal subgroups were sacrificed 2 hours after the last medication, while the ginseng-ACTH, the saline-ACTH, and the normal-ACTH subgroups received ACTH (0.1 unit/subject) 1 hour after the last medication and were sacrificed after 1 more hour. The mandibular gland was measured for RNA and DNA contents using the chemical method of Schmidt-Thanhauser-Schneider. Following results were obtained 1. RNA content of the mandibular gland and RNA/DNA ratio were significantly higher in the ginseng group than they were in the normal and the saline groups. The DNA content was significantly reduced in the ginseng group. 2. Administration of ACTH reduced nucleic acid contents of the mandibular gland. In the ginseng group the rate of decrease ((value of ginseng-ACTH subgroup-value of ginseng subgroup) X 100/value of ginseng subgroup) in RNA and RNA/DNA ratio were more conspicuous than they were in the normal and the saline groups. The rate of decrease in DNA after ACI'II was less conspicuous in the ginseng group. Thus under the influence of ginseng the mandibular glandular RNA content and RNA/DNA ratio increased significantly and DNA content decreased conspicuously while under additional influence of ACTH the rate of decrease was conspicuous in RNA content and RNA/DNA ratio but it was less so in DNA content.

      • KCI등재

        스펙트럼 영역 빛간섭단층촬영기를 이용한 근시 정도에 따른 황반 구조의 정량적 분석

        김승훈,박주연,박태관,온영훈,Seung Hoon Kim,Joo Youn Park,Tae Kwann Park,Young-Hoon Ohn 대한안과학회 2011 대한안과학회지 Vol.52 No.11

        Purpose: To investigate the correlation of macular retinal thickness and refractive error using spectral-domain optical coherence tomography (SD-OCT). Methods: A total of 120 eyes with no posterior abnormalities were enrolled in the present study. Subjects were divided into 3 groups based on their spherical equivalent. Visual acuity, refraction, slit lamp examination, tonometry and fundus examination were performed. Retinal thickness between the RPE and IS/OS junction was measured at the fovea, 1 mm (inner ring) and 2 mm (outer ring) superiorly, inferiorly, nasally and temporally using SD-OCT. Overall average thickness, average foveal thickness, and the inner and outer ring macular thickness were measured. Results: The average foveal thickness was significantly greater in the high myopic eyes than in the low to moderate myopic and emmetropic eyes (p = 0.001). However, the RPE-IS/OS junction thickness of the foveola and the outer macular thickness were significantly lower (p = 0.001, p = 0.002) in the high myopic eyes. There was a weak, but significant negative correlation between refractive error and average foveal thickness (r = -0.38, p = 0.001). A positive correlation was found between refractive error and the RPE-IS/OS junction thickness (r = 0.40, p = 0.001). Conclusions: Macular retinal thickness is related to refractive error in normal subjects. Effects of eyeball elongation are more apparent in high myopic eyes than in low to moderate myopic eyes. A significant decline in the RPE-IS/OS junction thickness suggests the photoreceptor outer segments in the foveola are damaged in high myopic eyes. J Korean Ophthalmol Soc 2011;52(11):1286-1295

      • KCI등재

        슬림 프리캐스트 슬래브 데크를 사용한 I-슬래브 시스템의 전단 성능에 관한 실험적 연구

        김승훈 한국구조물진단유지관리공학회 2017 한국구조물진단유지관리공학회 논문집 Vol.21 No.1

        본 연구는 원형 천공된 플랫 형태와 팔각형 형태의 중공을 가지는 슬래브의 전단강도를 평가하고 있다. 최근 건축구조물에서 슬래 브 두께에 대한 증가와 품질관리에서 요구되는 수준이 상향됨에 따라 프리캐스트 중공 슬래브 시스템에 대한 관심이 증가하고 있다. 중공 슬래 브 시스템은 널리 알려진 바와 같이 슬래브의 자중을 감소시킬 수 있는 효율적인 바닥시스템이다. 하지만 중공슬래브는 전단에 저항하는 슬래 브 웨브의 콘크리트 면적 감소로 전단강도 성능이 저하될 수 있다. 특히, 프리캐스트 중공슬래브는 PC 슬래브 데크의 접합면이 발생하며, 접합 면의 균열로 인한 전단파괴가 일어나지 않도록 방지하여야 한다. 본 연구에서는 I-슬래브 시스템의 전단강도를 평가하기 위하여 3점 가력에 의 한 주축 및 직교축에 대한 전단 실험을 실시하였다. 실험결과 I-슬래브가 PC 접합면이 포함되어짐에도 불구하고 이론강도에 대하여 충분한 전 단강도 성능을 보유하는 것으로 나타났다. This paper presents the shear capacities of hollow slab with plate and octagonal pillar type hollow sphere. Recently, the interest in precast hollow slab system for buildings is growing up according to the demand for high quality control and the increase in slab thickness. A hollow slab system is widely known as one of the effective slab system which can reduce self-weight of slab. However, hollow slabs are vulnerable to the deterioration in the shear strength due to the decrease of concrete at slab web which resists shear. Especially, in case of precast hollow slabs, it has joint surface between precast concrete slab modules along transverse axis of slab, and shear failure, that is caused by cracks at joints, has to be prevented. Therefore, in this study, shear capacity of the I-slab system is evaluated by 3-points-supported shear test along the longitudinal and transverse axis of slab specimen. Test results showed that I-slab had enough shear strength compared to theoretical shear strength even if it included the joint surfaces.

      • KCI등재후보

        PerFixR Plug을 이용한 무긴장 탈장 교정술의 단기 성적 보고

        김승훈,정재희,송영택 대한외과학회 2003 Annals of Surgical Treatment and Research(ASRT) Vol.64 No.5

        Purpose: The PerFixⓇ plug is preformed as a Marlex mesh hernia plug, and consists of a fluted outer layer combined with an inner arrangement of eight mesh "petals." In contrast to hand-rolled hernia plugs, which can collapse on themselves, the PerFixⓇ plug's petals maintain the device's open conelike shape. The fluted design allows the plug to more readily conform to the configuration of any indirect or direct defect. Methods: Bewteen January 1996 and April 2000 126 conventional herniorrhaphies (C group: Bassini: 23, Shouldice: 15, McVay: 5, Lichtenstein: 83) were performed, and between May 2000 and April 2002, 124 PerFixⓇ plug repairs (P group) were completed. The operation times, lengths of hospital stay, visual analogue pain scales, time of analgesics use, and complication and recurrence rates were compared between these two groups. Results: The operation times and lengths of hospital stay for groups C and P were 56.4 vs. 31.1 minutes and 4.4 vs. 2.8 days, respectively, so where significantly shorter in the P group (P<0.01). The times of use for the analgesics, AAP and Nubaine, were 6.6 vs. 0.6 times and 1.7 vs. 0.9 times, in group C and P, respectively, so were significantly fewer in the P group (P<0.01). There were 5 recurrences (3.9%) in the C group during the follow up period (2~6 years), but there were none in the P group during the follow up period (5 months~2 years). The complications were similar in both groups. Conclusion: Compared with conventional surgical techniques, including the Lichtenstein tension free method, the PerFixⓇ plug method is the most simple, and shows superiority in the following areas; the operation time, length of hospital stay, times of analgesics use and recurrence. However, with regard to the recurrence, longer follow up and observation periods are required. (J Korean Surg Soc 2003;64:429-433)

      • KCI등재

        Development Strength of Headed Reinforcing Bars for Steel Fiber Reinforced Concrete by Pullout Test

        김승훈,백성철,이창용,육현웅,이용택 대한건축학회 2018 Architectural research Vol.20 No.4

        In order to compare the development performance of headed reinforcing bar and straight reinforcing bar in tension for steel fiber reinforced concrete (SFRC), pullout test of specimens with reinforcing bar which was anchored on simple beam perpendicularly was conducted. The experimental variables were steel fiber volume ratio (VRsf), concrete compressive strength, and existence of head. As the result of test, splitting failure of concrete in the development direction of reinforcing bar in most specimens was observed. For development detail of headed reinforcing deformation bar, specimens with 1% VRsf showed approximately 63%~119% increase in pullout strength compare to specimens with 0% VRsf. Test result shows that SFRC is more effective in increasing pullout strength for headed reinforcing bars than increasing pullout strength of straight bars.

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