도화탕(桃花湯)이 백서(白鼠)의 소화성(消化性) 궤양(潰瘍) 및 장관수송능(腸管輸送能)에 미치는 영향(影響)

김수정,김진규,백정한,강석봉,이익행,Kim, Soo-Jung,Kim, Jin-Kyu,Back, Jung-Han,Kang, Seok-Bong,Lee, Ik-Haeing 대한한방내과학회 2001 大韓韓方內科學會誌 Vol.22 No.2

Objectives : In order to study the clinical efficiency of Dohwatang, based on Oriental Medical References, using experimental animals, we studied ulcers, gastric juice secretion, free acidity, total acidity, and the action of transport rates in the intestine. Methods : We used rats administered with the above herbs. Results : Dohwa-tang showed remarkable inhibitory effects on peptic ulcers, gastric juice secretion, free acidity, and total acidity in pyloricligated rat. It also showed remarkable inhibitory effects on the transportability in the large intestine of rats. But Dohwa-tang didn't show any remarkable difference on stressed rats. Conclusions : Dohwatang works better for chronic pyloristenosis-peptic ulcer and for diarrhea than acute stress ulcer.

감귤 내 생리활성성분이 간암세포의 생존에 미치는 영향

김수정,박덕배,Kim, Soo Jung,Park, Deok Bae 제주대학교 의과학연구소 2018 The Journal of Medicine and Life Science Vol.15 No.1

Previous studies have suggested that Citrus fruits might suppress the proliferation of various cancer cells. However, little is known about any specific ingredients in the extract of Citrus fruits to exert its anti-proliferative activity in cancer cells. The present study aimed to identify the active ingredients in Citrus fruits to suppress the proliferation of rat hepatocellular carcinoma cells. Among tested compounds, two polymethoxylated flavones (nobiletin and tangeritin) showed significant anti-proliferative activity whereas other compounds (synephrine, rutin, hesperidin) did not. Interestingly, nobiletin as well as tangeritin also decreased the protein amount of gluconeogenic enzymes, PEPCK and G6Pase. The possible involvement of gluconeogenic activity in the proliferation of hepatocellulacarcinoma cells are further to be investigated.

영어의 비강세 약모음 schwa /e/의 음성실현

김수정,Kim, Soo-Jung 한국음성학회 2005 음성과학 Vol.12 No.4

The present study examines the phonetic realizations of the unstressed weak vowel /e/ in English words produced by native and Korean ESL speakers. Traditionally, the stressed elements in utterance are considered to be prominent. In this sense, the unstressed weak vowel /e/ is predicted to be shorter in length, lower in pitch and intensity than the stressed vowels. The experiment shows that native English speakers correlate the unstressed weak vowel /e/ with both shorter duration and lower pitch; Korean ESL speakers correlate it with lower pitch only. We cannot find any significant statistical difference in intensity between /e/ and the stressed vowels in both cases. This study suggests it is important to acquire and produce the correct prosodic correlates of the unstressed weak vowel /e/ for Korean ESL speakers to command more natural English intonation, since /e/ is the most common vowel in English speech and consists of the English foot rhythm along with stressed vowels.

홍경천(Rhodiola sachalinensis A. Bor)의 캘러스 배양에서 Salidroside생산

김수정,황백,황성진,안준철,Kim, Soo-Jung,Hwang, Baik,Hwang, Sung-Jin,Ahn, Jun-Cheul 한국식물생명공학회 2004 식물생명공학회지 Vol.31 No.1

본 실험은 기내 배양된 홍경천으로부터 캘러스를 유도하고 가장 잘 자라는 생장조건을 찾기 위해 수행되었다. 실험 결과를 종합해 보면 캘러스의 증식을 위한 배양조건은 최적배지를 조사한 결과,2B$_{5}$배지에서 생장율이 가장 좋았으며, 탄소원으로는 sucrose를 3%로 첨가했을 때 생장율이 가장 높았다. 질소원으로써는 49.6mM KNO$_3$와 2.0mM (NH$_4$)$_2$SO$_4$를 첨가했을 때 생장율이 가장 좋았으며, 인산의 농도는 2.16mM에서 높은 생장율을 보였다. 암배양과 광배양을 비교했을 때 암배양의 경우가 생장율이 높았으며,pH6에서 세포의 생장율이 가장 좋은 조건임을 확인되었다. 기내에서 배양된 캘러스와 자연산 뿌리는 TLC로 분석하여 salidroside를 확인하였으며, HPLC로 salidroside를 정량한 결과, 자연상태 홍경천의 뿌리는 건중량 당 0.17%으로 나타났으며 5% sucrose처리구에서 0.41%의 생산성을 보여, 자연산 홍경천의 뿌리에 비하여 캘러스에서 salidroside의 함량이 높은 것으로 나타났다. Callus of Rhodiola sachalinensis A. Bor were induced from leaf explant on l/2MS solid supplemented with combination of auxin (2.4-D, NAA: 0.1∼2mg/L) and cytokinin (BA: 0.1∼0.2mg/L). The effects of various medium, culture conditions and phytohormones on the growth of callus were investigated. MS, WPM, B$_{5}$ medium and diluted or concentrated media (1/2X, 2X, 3X) were used to investigate the growth of callus on each media. Among these, the highest growth was observed when cultured in in 2B$_{5}$ medium containing 0.5mg/L NAA and 1mg/L BA, 3% sucrose and 49.6 mM KNO$_3$ as nitrogen source, and 2.16mM NaH$_2$PO$_4$ as phoshate source at $25^{\circ}C$ in the dark. The calli cultured with 5% sucrose produced high salidroside content (0.41% on the basis of dry wt) than normal root (0.17%).

건성피부 및 소양증에 대한 잘스밍R 크림의 임상효과에 대한 연구

김수정,이인욱,최응호,이원수,안성구 ( Soo Jung Kim,In Wook Lee,Eung Ho Choi,Won Soo Lee,Sung Ku Ahn ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.3

Background: Xerosis is a relatively common disorder, especially in the elderly. The condition is characterized by fine scaling and is associated with generalized pruritus. Objective : The purpose of this study was to evaluate the clinical efficacy, safety and tolerability of Zalsming cream in patients with xerosis and pruritus. Methods : Thirty patients were treated with Zalsming cream. Clinical efficacy, as measured by the score of subjective symptom and objective signs, transepidermal water loss(TEWL) and electron microscopic finding, were asessed at 2, 4, and 6 weeks after topical application of the cream. Results . The scores of clinical signs and TEWL showed statistically significant improvements. No one developed any local or systemic side effects. Conclusion : Topical application of Zalsming cream was found to be effective and safe for patients suffering from xerosis and pruritus. (Kor J Dermatol 1997;35(3): 418-423)

$(1-x)CaWO_4-xYNbO_4$계 세라믹스의 마이크로파 유전특성

김수정,김응수,Kim, Su-Jung,Kim, Eung-Soo 한국결정성장학회 2007 한국결정성장학회지 Vol.17 No.5

[ $(1-x)CaWO_4-xYNbO_4$ ]계에 대하여 $YNbO_4(0.05{\leq}x{\leq}0.4)$의 치환량 변화에 따른 마이크로파 유전특성을 고찰하였다. x=0.10 조성까지 정방정(tetragonal) scheelite 구조의 $CaWO_4$ 단일상이 확인되었고, 그 이상 첨가 시 fergusonite 구조의 2차상이 증가하였다. $YNbO_4$ 첨가량이 증가할수록 겉보기 밀도는 감소하였는데, 이는 $CaWO_4(6.117g/cm^3)$보다 $YNbO_4(5.581g/cm^3)$가 더 낮은 이론밀도 값을 갖기 때문이다. $YNbO_4$의 첨가량이 증가함에 따라 유전상수(K)와 품질계수(Qf)는 2차상의 증가와 밀도의 감소로 인해 감소하는 경향을 보였고, $YNbO_4$ 치환량에 따른 소결시편의 공진주파수 온도계수(TCF)의 변화는 존재상의 유전체 혼합 법칙(dielectric mixing rule)에 의존하였다. Microwave dielectric properties of $(1-x)CaWO_4-xYNbO_4$ ceramics have been investigated as a function of $YNbO_4$ content($0.05{\leq}x{\leq}0.4$). A single phase with tetragonal scheelite structure was obtained up to x=0.10 and then the secondary phase with fergusonite structure was increased. With the increase of $YNbO_4$ content, apparent densities of the specimens were decreased. This results were due to the lower theoretical density of $YNbO_4(5.581g/cm^3)$ than that of $CaWO_4(6.117g/cm^3)$. Dielectric constant(K) and quality factor(Qf) were decreased with $YNbO_4$ content which could be attribute to the decrease of density and the increase of secondary phase. Temperature coefficient of resonant frequency (TCF) of the specimens with the $YNbO_4$ content was depended on dielectric mixing rule.

가정외보호 퇴소 청소년의 원가족 관계 경험

김수정(Kim, Soo Jung),김지선(Kim, Ji Sun),정익중(Chung, Ick Joong) 한국아동복지학회 2017 한국아동복지학 Vol.- No.58

본 연구에서는 가정외보호 퇴소 청소년이 원가족과 어떠한 관계를 경험하는지를 살펴보고자 하였다. 이를 위해 가정외보호 퇴소 청소년 6명을 대상으로 면접을 통해 자료를 수집하였으며, 현상학적 방법을 적용하여 자료를 분석하였다. 본 연구의 결과는 다음과 같다. 본 연구에서 4개의 범주와 12개의 하위범주가 도출되었는데, 4개의 범주는 ‘혼돈 속의 헤어짐’, ‘다시 만났지만 거리가 생김’, ‘완전히 끝나버린 관계’, ‘새로 만드는 가족의 경계’로 구분되었다. 첫째, 빈곤이나 이혼 등의 문제로 부모와 분리된 연구참여자 3명은 부모와 다시 재회를 하였고, 퇴소 이후에도 관계를 지속하는 것으로 나타났다. 이들은 자립하는데 있어서 부모로부터 다양한 형태의 지원을 받고 있으며, 이러한 지원을 통해 안정적으로 자립을 해가고 있었다. 둘째, 심각한 아동학대, 부모의 죽음으로 부모와 분리된 경우는 부모와의 관계가 단절된 것으로 나타났다. 이들은 원가정이 아닌 새로운 대안관계를 통해 자립해 가고는 있지만 다소 불안정한 전이를 경험하였다. 본 연구에서 연구참여자의 원가족 관계 경험을 한마디로 요약하면 “애증의 외줄타기”로 정의 할 수 있다. 이러한 결과를 바탕으로 가정외보호 퇴소 청소년의 원가족 관계를 돕기 위한 아동복지 실천적 및 정책적 함의를 제언하였다. The purpose of this study was to explore relationships between family of origin and youth transitioning from out-of-home care. Data were collected from six youths transitioning from out-of-home care and were analyzed using the phenomenological approach. The results of this study were as follows. Four categories and twelve subcategories were drawn from the meaning units. The four categories were ‘chaos in separation’, ‘re-established relations but with distance’, ‘completely ended relationships with the family of origin’, and ‘redrawing family boundaries’. First, the participants who were separated from their parents due to poverty or divorce reunited with their parents, and they appeared to continue their relationships with the family of origin after transitioning from out-of-home care. The youth were receiving various forms of support from their parents in order to be independent, and they were experiencing stable independence through this support. Second, the participants who were separated from their parents due to serious child abuse or parental death had broken relationships with their parents. The youth were independent and relied on new alternative relationships that were not with the family of origin, but they experienced somewhat unstable self-reliance. In short, participants’ relationships with families of origin in this study can be defined as a tight rope between love and hate. Based on these results, child welfare practice and policy implications were discussed to help out-of-home care youth’s relationship with their family of origin.

영유아교사의 정서경험에 관한 연구 동향 분석

김수정(Soo Jung Kim) 한국보육학회 2018 한국보육학회지 Vol.18 No.3

Objective: By doing a more comprehensive review of recent domestic studies related to the emotions experienced by the early childhood teachers, the current study aims to suggests the direction of various emotional research experiences; and provide the basic data necessary for the development and application of a program that helps early childhood teachers experience more positive emotions in the child care setting and effectively addresses the negative emotional experience. Methods: 87 previous studies which were published in the journals related to various emotional experiences experienced by the early childhood teacher since 2008 were analyzed. Results: It was found that the emotion - related articles of early childhood teachers showed that, compared with before 2012, it increased after 2013. Also, the tendency of the data collection method was mostly composed of the papers using the questionnaire method using the test and the scale. As the most studied topic related to the emotional experience of early childhood teachers, the negative emotional experiences were the exhaustion experienced by the teachers. And the most studied topics on positive emotional experiences were the happiness experienced by early childhood teachers; The research that explores the variables related to the happiness experienced by the early childhood teachers was the majority. Conclusion/Implications: The analysis of this study suggests a systematic understanding of emotions experienced by early childhood teachers and suggests future directions for supporting healthy emotional experiences.

또래관계와 아동복지서비스가 피학대 아동의 학교적응에 미치는 영향 : 다중회귀분석과 경향점수분석의 비교

김수정 ( Kim Soo Jung ),정익중 ( Chung Ick Joong ) 한국보건사회연구원 2013 한국복지패널 학술대회 논문집 Vol.6 No.-

The purpose of this study is to examine the effects of peer relationships and experiences of child welfare service on school adjustment of abused children. This study utilizes the first, fourth, and seventh waves of Korean Welfare Panel Study(KWPS). The study sample consists of 344 children who experienced child abuse at least once in the first, fourth, and seventh waves. On the average, the more serious problems abused children have, the more frequent children use welfare services. Thus, this study adopted propensity score weight method to reduce the distortion of the results from the selection bias. The study confirms different statistical results between multiple regression analysis and propensity score weight method. The results from multiple regression analysis showed that peer attachment had positive effects on school adjustment of children experiencing child abuse. However, peer supports and experiences of child welfare services had statistically insignificant effects on school adjustment. On the other hand, propensity score weight method proved that experiences of child welfare service had significant effects on school adjustment of abused children. Based on the study findings, methods to improve peer attachment and to expend child welfare services for abused children were discussed.

장애학생을 위한 테크놀로지 기반 수학 문장제 문제 해결 중재의 효과

김수정(Soo Jung Kim) 한국특수교육학회 2022 한국특수교육학회 학술대회 Vol.2022 No.-

연구목적: The purpose of this meta-analysis is to systemically review the intervention studies that used instructional technology targeting to promote mathematical WPS performances of elementary and middle school students with disabilities. 연구방법: This study computed an overall effect and analyzed moderators of group design studies (Hedges’g) and single-case design studies (between-case standardized mean difference) in the same analyses. 연구결과: From the article identification based on inclusion and exclusion criteria, a total of 21 studies were included in this study. The overall effect of instructional technology on word problem solving across 21 studies was large (Hedge’ g = 1.18, 95% Cl = 0.84, 1.52). 결론: This meta-analysis indicate that instructional technology is promising to improve WPS performance for elementary and middle school students with disabilities.