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도화탕(桃花湯)이 백서(白鼠)의 소화성(消化性) 궤양(潰瘍) 및 장관수송능(腸管輸送能)에 미치는 영향(影響)
김수정,김진규,백정한,강석봉,이익행,Kim, Soo-Jung,Kim, Jin-Kyu,Back, Jung-Han,Kang, Seok-Bong,Lee, Ik-Haeing 대한한방내과학회 2001 대한한방내과학회지 Vol.22 No.2
Objectives : In order to study the clinical efficiency of Dohwatang, based on Oriental Medical References, using experimental animals, we studied ulcers, gastric juice secretion, free acidity, total acidity, and the action of transport rates in the intestine. Methods : We used rats administered with the above herbs. Results : Dohwa-tang showed remarkable inhibitory effects on peptic ulcers, gastric juice secretion, free acidity, and total acidity in pyloricligated rat. It also showed remarkable inhibitory effects on the transportability in the large intestine of rats. But Dohwa-tang didn't show any remarkable difference on stressed rats. Conclusions : Dohwatang works better for chronic pyloristenosis-peptic ulcer and for diarrhea than acute stress ulcer.
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김수정,Kim, Soo-Jung 한국음성학회 2005 음성과학 Vol.12 No.4
The present study examines the phonetic realizations of the unstressed weak vowel /e/ in English words produced by native and Korean ESL speakers. Traditionally, the stressed elements in utterance are considered to be prominent. In this sense, the unstressed weak vowel /e/ is predicted to be shorter in length, lower in pitch and intensity than the stressed vowels. The experiment shows that native English speakers correlate the unstressed weak vowel /e/ with both shorter duration and lower pitch; Korean ESL speakers correlate it with lower pitch only. We cannot find any significant statistical difference in intensity between /e/ and the stressed vowels in both cases. This study suggests it is important to acquire and produce the correct prosodic correlates of the unstressed weak vowel /e/ for Korean ESL speakers to command more natural English intonation, since /e/ is the most common vowel in English speech and consists of the English foot rhythm along with stressed vowels.
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홍경천(Rhodiola sachalinensis A. Bor)의 캘러스 배양에서 Salidroside생산
김수정,황백,황성진,안준철,Kim, Soo-Jung,Hwang, Baik,Hwang, Sung-Jin,Ahn, Jun-Cheul 한국식물생명공학회 2004 식물생명공학회지 Vol.31 No.1
본 실험은 기내 배양된 홍경천으로부터 캘러스를 유도하고 가장 잘 자라는 생장조건을 찾기 위해 수행되었다. 실험 결과를 종합해 보면 캘러스의 증식을 위한 배양조건은 최적배지를 조사한 결과,2B$_{5}$배지에서 생장율이 가장 좋았으며, 탄소원으로는 sucrose를 3%로 첨가했을 때 생장율이 가장 높았다. 질소원으로써는 49.6mM KNO$_3$와 2.0mM (NH$_4$)$_2$SO$_4$를 첨가했을 때 생장율이 가장 좋았으며, 인산의 농도는 2.16mM에서 높은 생장율을 보였다. 암배양과 광배양을 비교했을 때 암배양의 경우가 생장율이 높았으며,pH6에서 세포의 생장율이 가장 좋은 조건임을 확인되었다. 기내에서 배양된 캘러스와 자연산 뿌리는 TLC로 분석하여 salidroside를 확인하였으며, HPLC로 salidroside를 정량한 결과, 자연상태 홍경천의 뿌리는 건중량 당 0.17%으로 나타났으며 5% sucrose처리구에서 0.41%의 생산성을 보여, 자연산 홍경천의 뿌리에 비하여 캘러스에서 salidroside의 함량이 높은 것으로 나타났다. Callus of Rhodiola sachalinensis A. Bor were induced from leaf explant on l/2MS solid supplemented with combination of auxin (2.4-D, NAA: 0.1∼2mg/L) and cytokinin (BA: 0.1∼0.2mg/L). The effects of various medium, culture conditions and phytohormones on the growth of callus were investigated. MS, WPM, B$_{5}$ medium and diluted or concentrated media (1/2X, 2X, 3X) were used to investigate the growth of callus on each media. Among these, the highest growth was observed when cultured in in 2B$_{5}$ medium containing 0.5mg/L NAA and 1mg/L BA, 3% sucrose and 49.6 mM KNO$_3$ as nitrogen source, and 2.16mM NaH$_2$PO$_4$ as phoshate source at $25^{\circ}C$ in the dark. The calli cultured with 5% sucrose produced high salidroside content (0.41% on the basis of dry wt) than normal root (0.17%).
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김수정,박덕배,Kim, Soo Jung,Park, Deok Bae 제주대학교 의과학연구소 2018 The Journal of Medicine and Life Science Vol.15 No.1
Previous studies have suggested that Citrus fruits might suppress the proliferation of various cancer cells. However, little is known about any specific ingredients in the extract of Citrus fruits to exert its anti-proliferative activity in cancer cells. The present study aimed to identify the active ingredients in Citrus fruits to suppress the proliferation of rat hepatocellular carcinoma cells. Among tested compounds, two polymethoxylated flavones (nobiletin and tangeritin) showed significant anti-proliferative activity whereas other compounds (synephrine, rutin, hesperidin) did not. Interestingly, nobiletin as well as tangeritin also decreased the protein amount of gluconeogenic enzymes, PEPCK and G6Pase. The possible involvement of gluconeogenic activity in the proliferation of hepatocellulacarcinoma cells are further to be investigated.
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$(1-x)CaWO_4-xYNbO_4$계 세라믹스의 마이크로파 유전특성
김수정,김응수,Kim, Su-Jung,Kim, Eung-Soo 한국결정성장학회 2007 한국결정성장학회지 Vol.17 No.5
Microwave dielectric properties of $(1-x)CaWO_4-xYNbO_4$ ceramics have been investigated as a function of $YNbO_4$ content($0.05{\leq}x{\leq}0.4$). A single phase with tetragonal scheelite structure was obtained up to x=0.10 and then the secondary phase with fergusonite structure was increased. With the increase of $YNbO_4$ content, apparent densities of the specimens were decreased. This results were due to the lower theoretical density of $YNbO_4(5.581g/cm^3)$ than that of $CaWO_4(6.117g/cm^3)$. Dielectric constant(K) and quality factor(Qf) were decreased with $YNbO_4$ content which could be attribute to the decrease of density and the increase of secondary phase. Temperature coefficient of resonant frequency (TCF) of the specimens with the $YNbO_4$ content was depended on dielectric mixing rule.
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건성피부 및 소양증에 대한 잘스밍R 크림의 임상효과에 대한 연구
김수정,이인욱,최응호,이원수,안성구 ( Soo Jung Kim,In Wook Lee,Eung Ho Choi,Won Soo Lee,Sung Ku Ahn ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.3
Background: Xerosis is a relatively common disorder, especially in the elderly. The condition is characterized by fine scaling and is associated with generalized pruritus. Objective : The purpose of this study was to evaluate the clinical efficacy, safety and tolerability of Zalsming cream in patients with xerosis and pruritus. Methods : Thirty patients were treated with Zalsming cream. Clinical efficacy, as measured by the score of subjective symptom and objective signs, transepidermal water loss(TEWL) and electron microscopic finding, were asessed at 2, 4, and 6 weeks after topical application of the cream. Results . The scores of clinical signs and TEWL showed statistically significant improvements. No one developed any local or systemic side effects. Conclusion : Topical application of Zalsming cream was found to be effective and safe for patients suffering from xerosis and pruritus. (Kor J Dermatol 1997;35(3): 418-423)
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김수정 ( Kim Soo-jung ) 백록어문교육학회 2022 백록어문교육 Vol.30 No.0
This study aims to examine the current status and future of Korean language textbooks in post-pandemic Japan. To this end, we introduce the textbooks used by the Japanese public broadcaster NHK in their television and radio broadcasted Korean lectures, overview Korean language textbooks for Japanese universities, and discuss whither developers of new textbooks should aspire. We argue that textbooks for Korean language learners in Japan should primarily target intermediate to advanced learners. They should preferably match the vocabulary and grammar level set by the International Standard Curriculum of Korean Language, while maintaining enough variety to address the needs of each learner. Furthermore, these textbooks should assume a high degree of self-directed learning. Current digital textbooks employed by broadcasted Korean lectures provide sufficient enjoyment and diversion to learners. Therefore, higher-level textbooks should aim to enable learners to expand their vocabulary and expressiveness by providing a sufficiently diverse set of language tasks. In particular, we contend that there should be no shortage of sociocultural material to pique readers’ intellectual curiosity, learners be granted the opportunity to increase their reading and writing abilities while gaining the skills necessary to speak and listen in various conversational contexts including presentations, interviews, and debates.
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김수정 ( Soo Jung Kim ),강원찬 ( Won Chan Kang ),김선웅 ( Sun Woong Kim ),이윤정 ( Yoon Jeong Lee ),김욱연 ( Wookyoun Kim ),김현정 ( Hyun Jeong Kim ),이홍기 ( Hong Ghi Lee ) 대한내과학회 2014 대한내과학회지 Vol.87 No.6
Adult T-cell leukemia/lymphoma (ATLL) is a highly aggressive disease that is geographically clustered, mirroring areas endemic for human T-cell lymphotropic virus type 1 infection. Most patients with ATLL present with aggressive manifestations such as severe hypercalcemia, lymphadenopathy, hepatosplenomegaly, and bone marrow involvement with progressive thrombocytopenia. We herein report a case of a patient with ATLL exhibiting increased uptake in both lungs as shown on a bone scan using 99mTc methylene diphosphonate. This finding is thought to have been caused by metastatic calcification associated with ectopic parathyroid hormone production. (Korean J Med 2014,87:750-755)
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