http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
일차 배양한 흰쥐의 간세포에서 사염화탄소로 인한 독성에 미치는 비테인의 효과
김선여(Sun Yeou Kim),김홍표(Hong Pyo Kim),이미경(Mi Kyeong Lee),김승희(Seung Hee Kim),문애리(A Ree Moon),한형미(Hyung Mi Han),허훈(Hoon Huh),김영중(Young Choong Kim) 대한약학회 1993 약학회지 Vol.37 No.5
Betaine, a major component of Lycii Fructus, was evaluated for its anti-hepatotoxic activity on carbon tetrachloride-induced hepatotoxicity in primary cultured rat hepatocytes. Betaine was found to attenuate carbon tetrachloride-induced hepatotoxicity both morphologically and biochemically. Typical hepatocyte necrosis due to carbon tetrachloride seemed to be reduced by 50 to 500mcM of betaine under microscopical observation. The value of glutamic pyruvic transaminase released from the hepatocytes into the medium significantly decreased as betaine concentration increased. Betaine also significantly elevated the reduced activities of some enzymes, cytochrome P-450, 7-ethoxycoumarin-O-deethylase and glutathione-S-transferase, involved in xenobiotic metabolism due to carbon tetrachloride-induced hepatotoxicity. These results demonstrate a possible hepato-protective role of betaine against fatty liver that could be easily induced by carbon tetrachloride.
신경섬유종증에 동반된 가성동맥류 파열로 발생한 자연 혈흉
김순종 ( Kim Sun Jong ),정훈 ( Jeong Hun ),이성순 ( Lee Seong Sun ),임채만 ( Im Chae Man ),이상도 ( Lee Sang Do ),고윤석 ( Go Yun Seog ),김우성 ( Kim U Seong ),김동순 ( Kim Dong Sun ),김원동 ( Kim Won Dong ),심태선 ( Sim Tae Seon 대한결핵 및 호흡기학회 2001 Tuberculosis and Respiratory Diseases Vol.50 No.1
김선여(Sun Yeou Kim),김영중(Young Choong Kim),변순정(Soon Jung Byun),김은(Eun Kim) 한국생약학회 1992 생약학회지 Vol.22 No.4
Liver protective effects of ginsenosides as well as fractions of dammarane glycosides of Panax ginseng were studied using galactosamine (Ga1N)-induced cytotoxicity in primary cultured rat hepatocytes. Preventing effects on Ga1N-induced hepatotoxicity were found both microscopic observation and determination of GPT level with total dammarane glycosides fraction and 20(S)-ginsenoside-Rb₁ as well as 20(S)-ginsenoside-Rg₁ at the concentration of 50 ㎍/㎖. The syntheses of both protein and RNA were significantly increased by the treatment of 50 ㎍/㎖ of total dammarane glycoside fraction, 20(S)-ginsenoside-Rb₁, -Rc, -Re and -Rg₁, respectively in both normal and Ga1N-induced cytotoxic hepatocytes.
항혈전스타킹과 간헐적공기압박기 적용이 중환자의 심부정맥혈전 발생 예방에 미치는 효과
김화순(Kim, Hwasoon),조옥민(Cho, Ok Min),김지선(Kim, Ji Sun),장해옥(Jang, Hai Ok),김여경(Kim, Yeo Kyeong),김설희(Kim, Seol Hee),민효남(Min, Hyo Nam),곽경선(Kwak, Kyung Sun),홍기천(Hong, Kee Chun),김장용(Kim, Jang Yong),정준호(Chung, 기본간호학회 2015 기본간호학회지 Vol.22 No.3
Purpose: The purpose of this pilot study was to investigate the effects of mechanical interventions for deep vein thrombosis (DVT) prophylaxis in surgical intensive care unit (SICU) patients. Methods: The participants were assigned to the intermittent pneumatic compression (IPC) and graduated compression stocking (GCS) intervention. Patients who met the criteria were selected for comparison from our previous study. Data for 140 patients were included in the final analysis. Results: The mean age was 57.5 (±15.7) and 61.4 % were men. About forty-seven percent of the participants were 61 years or over. In the second duplex scan, 3, 2 and 1 critically ill patients developed deep vein thrombosis in the control, GCS, and IPC groups, respectively. Incidences of DVT were 6.0%, 5.0%, and 2.0% for the control, GCS, and IPC groups, respectively. This difference was not significant. Relative risks of no intervention were 3.0 and 1.2 compared with IPC and GCS application. There were no significantly different variables among the three groups before the intervention except for diagnosis on admission. Conclusion: Although it may difficult to conclude that mechanical prophylaxis effectively prevents DVT among SICU patients because there was no statistical significance in this study, but incidence rates among the three groups differed greatly. The findings reveal that further study should be conducted with larger samples and randomized controlled trial for SICU patients.
운동이상형 소화불량증을 호소하는 당뇨병 환자에서 주석산 시사프리드의 효과
김선명(Sun Myung Kim),추교영(Kyo Young Choo),최명규(Myung Gyu Choi),김진일(Jin Il Kim),방춘상(Choon Sang Bhang),한석원(Sok Won Han),김병욱(Byung Wook Kim),최황(Hwang Choi),김성수(Sung Soo Kim),이동수(Dong Soo Lee),최규용(Kyu Yong Ch 대한소화기기능성질환·운동학회 2001 Journal of Neurogastroenterology and Motility (JNM Vol.7 No.1
N/A evaluated the effects of cisapride tartrate on gastrointestinal symptoms and gastric emptying times in diabetic patients with dysmotility like dyspeptic symptoms. Methods: Cisapride was administered before each meal in 61 patients for 4 weeks. The intensity of gastrointestinal symptoms before and after cisapride administration was scored from 0 to 4, in the order of increasing severity of symptoms. In addition, a gastric emptying test was performed. Results: A significant reduction in the total intensity score of symptoms was observed during the first two weeks, from 8.5±2.1 to 4.0±3.0 (p<0.05), and a further reduction was noted during the next two weeks, to 2.8±2.8 (p<0.05). Good to excellent improvement was obtained in 70.4% of the patients, but the improvement in symptoms was not related to age, duration of diabetes, glucose, Hb A1c, neuropathy, or retinopathy. Treatment with cisapride induced a significant regression of symptoms and a significant improvement of delayed gastric emptying from 104.0± 31.7 minutes to 79.5±17.1 (p<0.05). However, there was a lack of association between the changes in gastric emptying times and improvements in symptoms(r2=0.00186). Only 3 patients complained of loose stool, nausea, or dizziness. Conclusions: Cisapride was effective in improving dysmotility like dyspeptic symptoms in diabetic patients without serious side effects. (Korean Journal of Gastrointestinal Motility 2001;7:56-64)