흰쥐의 좌골신경 절단손상후 기능회복에 대한 Acetyl-L carnitine의 효과

조주원,이정재,손유리,유영천,유석근 大韓成形外科學會 1999 Archives of Plastic Surgery Vol.26 No.3

A possible therapeutic effect of acetyl-L carnitine (ALCAR) on peripheral nerve injuries and the expression of Jun, the protein products of immediate-early genes(IEGs), in the spinal cord were investigated after sciatic nerve injury in Sprague-Dawley rats. Experimental animals were divided into 3 groups: intact sciatic nerve as a control group, surgical repair alone, and surgical repair with ALCAR treatment. Toe-spreading response, pinprick response, and compound action potential were measured to evaluate the recovery of sciatic nerve injury. Recovery of behavioral function and electrophysiological function both improved in the surgical repair with ALCAR treatment group. Weak basal expression of Jun was shown in the ventral horn the of spinal cord in the control group. In the surgical repair alone group or the surgical repair with ALCAR treatment group, Jun expression persisted until 28 days after injury in the ventral horn of the spinal cord. Moreover, the surgical repair with ALCAR treatment group showed more increased expression of Jun than the surgical repair alone group. These results suggest that ALCAR facilitates the functional recovery after peripheral nerve injury.

머리-목 회전이 편부전마비 환자의 팔꿈치 신전근력에 미치는 영향

유욱재,이상은,이정원 한국전문물리치료학회 1997 한국전문물리치료학회지 Vol.4 No.1

第7次 敎育課程에 따른 初等學校建築의 使用者 要求에 관한 硏究

유길준,김재원,윤정근 동아대학교 건설기술연구소 2001 硏究報告 Vol.25 No.1

The purpose of this study is to seek the basic information for the planning of modernized elementary schools in response to the 7th National Curriculum. The results of this study are as follow; 1) A multi-purpose space is put with a corridor beside classrooms as a open classroom, therefore it is increasing to demand that the multi-purpose space should be separated from the classrooms and be closed up with fixed wall, because the property of open space, the use of sound-absorbing powerless finishing materials, scarce furnitures and deficient movable partitions raise noises. In addition, it is required to aid budget for teaching tools and furniture according to supplying multi-purpose space in response to various and particular education method, and it is needed to have mind to use multi-purpose space efficiently. 2) Teachers prefer that teachers' rooms (for a grade unit) are near to classrooms and they require to secure enough space to hold a grade unit meetings. 3) To solve the problems of the method of provision with meals, it is required to research and experiment. For example, I suggest to apply the method of classroom provision to low grade students and apply the method of dining room provision to middle and high grade.

국내 정신과 의사의 항정신병 약물 장기 지속형 주사제 처방에 대한 인식조사

박한선,배승민,유재홍,김수인,임원정 大韓神經精神醫學會 2009 신경정신의학 Vol.48 No.3

Objectives Long acting injectable antipsychotic medication have the ability to sustain the drug effect for a long duration, thus enabling advances in the management of those psychiatric patients who have poor compliance or who have difficulty getting the oral form of their antipsychotic medications. Despite their benefits, previous studies have reported that depot antipsychotics have a much lower prescription ratein the treatment of schizophrenia or schizoaffective disorder. Psychiatrist's attitude toward depot antipsychotics clearly has an influence on the decision-making process regarding the selection of medications. Until now, there has been no data with respect to psychiatrists' attitudes regarding long-acting injectable antipsychotics in Korea. This Study examined these attitudes toward antipsychotic depot medications as well as the factors which could contribute to their choice of deports. Methods We questioned 347 psychiatrists, who had been attending a conference, about their attitudes toward depot antipsychotic treatment. Results The most important factor causing reluctance with respect to prescribing depot treatment (for both classes of antipsychotics) was a presumed sufficient level of compliance with available oral antipsychotic treatments. In addition, typical depots are not considered to be an appropriate treatment option for first-episode patients, and as a result, they are used sparingly. Lastly, atypical long-acting injectable drugs are avoided due to their strict criteria of insurance and high treatment costs. Conclusion Aversions to prescribe depot treatment are frequent among psychiatrists and appear to be unrelated to the antipsychotic class. The stated reasons for not choosing depots are generally not supported by the current literature. Further research is required to clarify the advantages using depot treatments.

요양급여 적정성 평가체계 혁신 중장기 계획

김상지,전숙경,이창원,정영애,안재영,안유미,권아영,임상희,최정남,윤미선,변의형,조미현 건강보험심사평가원 2021 HIRA RESEARCH Vol.1 No.2

Methyl Jasmonate Increases Isoflavone Production in Soybean Cell Cultures by Activating Structural Genes Involved in Isoflavonoid Biosynthesis

Jeong, Yu Jeong,An, Chul Han,Park, Sung-Chul,Pyun, Jang Won,Lee, Jiyoung,Kim, Suk Weon,Kim, Hyun-Soon,Kim, HyeRan,Jeong, Jae Cheol,Kim, Cha Young American Chemical Society 2018 Journal of agricultural and food chemistry Vol.66 No.16

<P>Isoflavonoids are a class of biologically active natural products that accumulate in soybean (<I>Glycine max</I> L.) seeds during development, play vital roles in plant defense, and act as phytoestrogens with important human health benefits. Plant cell suspension cultures represent an excellent source of biologically important secondary metabolites. We found that methyl jasmonate (MJ) treatment increased isoflavone production in soybean suspension cell cultures. To investigate the underlying mechanism, we examined the expression of structural genes (<I>CHS6</I>, <I>CHS7</I>, <I>CHI1</I>, <I>IFS1</I>, <I>IFS2</I>, <I>IFMaT</I>, and <I>HID</I>) in the isoflavonoid biosynthesis pathways in soybean suspension cells under various abiotic stress conditions. MJ treatment had the most significant effect on gene expression and increased the production of three glycosidic isoflavones (daidzin, malonyldaidzin, and malonylgenistin), with the maximum total isoflavone production (∼10-fold increase) obtained on day 9 after MJ application. MJ treatment significantly increased total phenolic contents and upregulated isoflavonoid biosynthesis genes, shedding light on the underlying mechanism.</P> [FIG OMISSION]</BR>

DOAS/CRCP 시스템 설계

Jeong, Jae-Weon 대한설비공학회 2006 설비저널 Vol.35 No.12

For the Designing a Dedicated Outdoor Air System with Ceiling Radiant Cooling Panels the concept of a dedicated outdoor air system(DOAS) with parallel sensible cooling was born from the decoupled system concept, which can be summarized as decoupling of ventilation and air-conditioning functions, or decoupling of sensible and latent load functions. First , remove the latent loads from the outside air(OA) intake and generated in spaces using a 100% OA ventilation system(i.e., DOAS). Second, remove the space sensible loads using a parallel mechanical cooling system, such as fan coil units, conventional variable air volume , and ceiling radiant cooling panel(CRCP) independent of the ventilation system.

연구원 활동 : 발표논문요약 ; < 건축공학분야 >

(Jae Weon Jeong),(Byung Ho Kang),(Min Hwan Yang),(Kang Soo Kim) 고려대학교 공학기술연구소 1996 생산기술연구소보 Vol.3 No.-

Soil pH and electrical conductivity are key edaphic factors shaping bacterial communities of greenhouse soils in Korea

Jeong Myeong Kim,An-Sung Roh,Seung-Chul Choi,Eun-Jeong Kim,Moon-Tae Choi,Byung-Koo Ahn,Sun-Kuk Kim,Young-Han Lee,Jae-Ho Joa,Seong-Soo Kang,Shin Ae Lee,Jae-Hyung Ahn,Jaekyeong Song,Hang-Yeon Weon 한국미생물학회 2016 The journal of microbiology Vol.54 No.12

Soil microorganisms play an essential role in soil ecosystem processes such as organic matter decomposition, nutrient cycling, and plant nutrient availability. The land use for greenhouse cultivation has been increasing continuously, which involves an intensive input of agricultural materials to enhance productivity; however, relatively little is known about bacterial communities in greenhouse soils. To assess the effects of environmental factors on the soil bacterial diversity and community composition, a total of 187 greenhouse soil samples collected across Korea were subjected to bacterial 16S rRNA gene pyrosequencing analysis. A total of 11,865 operational taxonomic units at a 97% similarity cutoff level were detected from 847,560 sequences. Among nine soil factors evaluated; pH, electrical conductivity (EC), exchangeable cations (Ca2+, Mg2+, Na+, and K+), available P2O5, organic matter, and NO3-N, soil pH was most strongly correlated with bacterial richness (polynomial regression, pH: R2 = 0.1683, P < 0.001) and diversity (pH: R2 = 0.1765, P < 0.001). Community dissimilarities (Bray-Curtis distance) were positively correlated with Euclidean distance for pH and EC (Mantel test, pH: r = 0.2672, P < 0.001; EC: r = 0.1473, P < 0.001). Among dominant phyla (> 1%), the relative abundances of Proteobacteria, Gemmatimonadetes, Acidobacteria, Bacteroidetes, Chloroflexi, and Planctomycetes were also more strongly correlated with pH and EC values, compared with other soil cation contents, such as Ca2+, Mg2+, Na+, and K+. Our results suggest that, despite the heterogeneity of various environmental variables, the bacterial communities of the intensively cultivated greenhouse soils were particularly influenced by soil pH and EC. These findings therefore shed light on the soil microbial ecology of greenhouse cultivation, which should be helpful for devising effective management strategies to enhance soil microbial diversity and improving crop productivity.

이황의 7정 이해 ―「예운」에서 『중용』으로

정원재 ( Weon Jae Jeong ) 퇴계학연구원 2015 退溪學報 Vol.137 No.-

이 글에서는 ‘「예운」의 7정과 『중용』의 희로애락 4정의 차이’가 어떻게 사칠논쟁의 논지 구성에 개입되는지를 이황을 중심으로 살펴보려 한다. 7정에 대한 이황의 견해는 왕복서한의 제2서를 기점으로 상당한 변화가 있는데, 이것은 「예운」의 7정과 『중용』의 4정을 같은 것으로 보는 기대승의 생각을 이황이 전면적으로 수용하면서 필연적으로 밟게 되는 길이기도 하다. 7정에 대한 이황의 생각이 바뀌어 가는 과정은, 「천명도설」과 「퇴계1서」→「퇴계2서」와 「퇴계3서」→「퇴계4서」와 「심통성정도설」의 단계로 정리할 수 있다. 「천명도설」에서 7정은 형기에 기원을 둔 것으로 인심과 동일시되면서 ‘사악함으로 흐르기 쉬운 것’으로 이해되었다. 이는 「예운」의 7정관을 수용한 것이라고 할 수 있다. 반면 부분적으로는 「퇴계 2서」부터, 더 명확하게는 「심통성정도설」 이후부터 7정은 본성에 기원을 둔 것으로 여겨지면서 ‘선하지 않음이 없는 것’으로 파악되었다. 이것은 『중용』의 구조 안에서 7정을 설명하면서 생겨나는 변화이다. 이 때문에 7정은 처음에는 개인적인 것[私]이므로 인심과 같은 것이라고 간주되었다가, 최종적으로는 공적인 것[公]이라고 해석되면서 인심과도 구분되기에 이르렀다. 7정에 대한 생각이 바뀌면서, 전체적인 마음에 대한 이해도 변하였다. 「천명도설」에서는 4단과 7정의 서로 다른 기원이 강조되면서 본성과 형기가 인간 마음 안의 대등한 두 구성요소로 자리하고 있었다. 반면, 「심통성정도설」에서는 본연지성과 기질 사이에 명확한 위계가 설정되면서 인의예지의 본성은 확고한 마음의 본질로 인식되게 되었다. 따라서 마음의 성격 역시 가치중립적인 마음에서 본질적으로 도덕적인 마음으로 달리 이해되었으며, 마음의 주재 역시 상반된 지향 속의 선택이 아니라 자신의 본질을 충실히 이행하는 것으로 역할이 바뀌었다. 마음 이해의 이런 변화를 이기론으로 옮겨 본다면, 「천명도설」에서 마음의 동력은 5상과 기질 둘이었으며 따라서 마음의 구조 역시 리기이원적이라고 할 수 있겠다. 하지만 「심통성정도설」에서는 본성이라는 단일한 원천이 유일한 마음의 동력이 되면서 마음의 구조 역시 전체적으로 리일원적인 것이 된다. 따라서 「심통성정도설」 이후에도 이황의 사칠론은 형식적으로는 리발과 기발이라는 호발설의 형태를 유지하긴 하지만, 내용적으로는 사실상 리발일로설의 구조와 의미를 지닌 것으로 볼 수 있다. 7정과 관련된 이황 이론의 이런 일련의 변화는 결국 「예운」의 7정 에서 『중용』의 4정으로 옮겨간 과정이라고 요약할 수 있겠다. In this paper, I illustrate how the difference between the seven emotions from the ‘Li Yun’ chapter of the Liji and the four emotions from the Zhongyong affects the construction of arguments in the Four-Seven debate, mainly in the case of Yi Hwang. From a starting point in his second letter to Ki Tae-Seung, Yi Hwang’s view of the seven emotions went through significant changes, as was logically necessary for him to accept Ki’s idea of equating the seven emotions mentioned in the Li Yun chapter and the four mentioned in the Zhongyong. In fact, Yi’s changing views of the seven emotions can be outlined in three stages: the first being the stage of his Diagrammatic Treatise of the Heavenly Mandate and his first letter to Ki Tae-Seung, the second being the stage of his second and third letters to Ki, and the third being the stage of his fourth letter to Ki and his Diagrammatic Treatise of the Mind Governing Nature and Emotion. In his Diagrammatic Treatise of the Heavenly Mandate, Yi Hwang understood the seven emotions to originate from the body, to be identical to the heart following human desires (in contrast to the heart following the Way), and consequently, to be something that easily becomes evil. This reflects his acceptance of the seven emotions as presented in the Li Yun chapter. However, his view that the seven emotions arise from the original nature and is therefore good is partially expressed in his second letter and more clearly in his Diagrammatic Treatise of the Heavenly Mandate. This is a change brought on by an attempt to explain the seven emotions within the structure of the Zhongyong. This is why the seven emotions which were considered what is personal (私si) and similar to the heart following human desires at the beginning, ended up being interpreted as what is public (公 gong) and distinguished from the heart following human desires. As his view of the seven emotions changed, his understanding of mind in general changed also. In his Diagrammatic Treatise of the Heavenly Mandate, the four beginnings and the seven emotions are two equal components in the human heart, since their separate origins are emphasized. In his Diagrammatic Treatise of the Mind Governing Nature and Emotion, however, the original nature and form and matter are placed in a clear hierarchical order, and the original nature of benevolence, righteousness, propriety and wisdom is firmly perceived as the essence of mind. Accordingly, his view of mind changed from characterizing it as what is morally neutral to what is essentially moral, and in the function of its ministry from choosing among opposing pursuits to performing the essence of mind faithfully. This change in his understanding of mind, as applied to the theory of principle (li) and material force (qi) in the Diagrammatic Treatise of the Heavenly Mandate, makes the motivating source of mind twofold, i.e. the five constants and form and material force, and therefore the structure of mind here can be said to be li-qi dualistic. In the Diagrammatic Treatise of the Mind Governing Nature and Emotion, however, the original nature is considered to be the single motivating source of mind, and the structure of mind turns out to be li-monistic. As a consequence, even after the Diagrammatic Treatise of the Mind Governing Nature and Emotion, Yi Hwang’s theory in the four-seven debate kept the dualistic form of mutual issuance of principle and material force, in which the four beginnings are the issuance of principle and the seven emotions are that of material force, but in reality it has the structure and meaning of the theory of a single route of issuance of principle. The series of Yi Hwang’s theoretical changes concerning the seven emotions can be summarized as the process of his shift from the seven- emotion paradigm from the Li Yun chapter to the four-emotion paradigm from the Zhongyong.