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출판 만화 기업의 소셜 네트워크 서비스 게시글의 속성이 소비자 호응도에 미치는 영향
전혜선(Hyesun Jeon),신형덕(Hyung-Deok Shin) 한국콘텐츠학회 2013 한국콘텐츠학회논문지 Vol.13 No.1
현재 출판 만화 시장은 장기적인 불황에 대처하기 위한 방법을 모색하고 있다. 그 일환으로서 인터텟 환경을 이용한 다양한 기법들이 개발되고 있는데, 이에 대한 선행연구는 웹 환경을 이용한 컨텐츠인 웹툰에 주로 집중되어 있으며 소셜 네트워크 서비스 활용에 대한 연구는 미진했다. 이에 본 연구는 소셜 미디어상의 게시글의 속성이 소비자 호응도에 미치는 영향에 대해 조사하였다. 연구대상으로는 시각문화 전문출판사인 세미콜론의 페이스북 페이지를 선정하였으며, 총 277개의 게시글을 수집하였다. 그리고 게시글의 속성에 따라 달린 댓글수와 공감수를 통해 소비자의 호응도를 측정하였다. 그 결과 시각적 정보를 포함한 게시글과 이벤트 참여를 유도하는 게시글은 소비자의 호응도에 유의한 정(+)의 영향을 미쳤으나, 정보량이 많은 게시글은 유의한 부(-)의 영향을 미쳤음을 발견하였다. 본 연구의 결과는 향후 기업들이 소셜네트워크 서비스 활동을 통한 소비자와의 소통에 있어서의 시사점을 던져주고 있다. Recently, comics pulication industry is experiencing long-time recess in Korean market. To overcome the difficulties firms are trying to develop various tools which fit new technological environments, but previous research tend to have focused too much on web-base contents such as webtoons, rather than communication effectiveness through social network services. Thus, this study investigated the relationship between the characteristics of postings at social network service and the consumer responsiveness. In the results, we found that posting with visual images and event invitations were positively associated with consumer responsiveness, and the amount of information was negatively associated with the responsiveness. This study shows some implications on how firms can effectively enhance communication with consumers through social network service.
면역저하 소아에서 발생한 다제내성 녹농균 균혈증을 ceftolozane-tazobactam으로 성공적으로 치료한 증례보고
Yu Hyesun,Shin Areum,Kim Doo Ri,Choi Jaeyoung,Ju Hee Young,Cho Joongbum,Kang Cheol-In,김예진 대한소아감염학회 2023 Pediatric Infection and Vaccine Vol.30 No.1
With the widespread use of broad-spectrum antibiotics in clinical practice, the emergence of multidrug-resistant (MDR) gram-negative bacteria has become a global problem. The MDR Pseudomonas aeruginosa infection is especially difficult to treat and increases mortality in critically ill patients. Ceftolozane-tazobactam (Zerbaxa™) is a fifth-generation cephalosporin and beta-lactamase inhibitor that has proved to be effective for treating complicated urinary tract infections and complicated intra-abdominal infections caused by MDR P. aeruginosa. Herein, we report the first case of pediatric hematologic cancer in Korea that was successfully treated for MDR P. aeruginosa bacteremia with Ceftolozane-tazobactam.
Hyun Hyesun,Ahn Yo Han,Park Eujin,Choi Hyun Jin,Han Kyoung Hee,Lee Jung Won,Kim Su Young,Yang Eun Mi,Suh Jin-Soon,Shin Jae Il,Cho Min Hyun,Koo Ja Wook,Kim Kee Hyuck,Park Hye Won,Ha Il-Soo,Cheong Hae I 대한소아신장학회 2023 Childhood kidney diseases Vol.27 No.2
Purpose: Angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers (ARBs) are frequently employed to counteract the detrimental effects of proteinuria on glomerular diseases. However, the effects of ARBs remain poorly examined in pediatric patients with immunoglobulin A (IgA) nephropathy. Herein, we evaluated the efficacy and safety of losartan, an ARB, in pediatric IgA nephropathy with proteinuria. Methods: This prospective, single-arm, multicenter study included children with IgA nephropathy exhibiting proteinuria. Changes in proteinuria, blood pressure, and kidney function were prospectively evaluated before and 4 and 24 weeks after losartan administration. The primary endpoint was the difference in proteinuria between baseline and 24 weeks. Results: In total, 29 patients were enrolled and received losartan treatment. The full analysis set included 28 patients who received losartan at least once and had pre- and post-urinary protein to creatinine ratio measurements (n=28). The per-protocol analysis group included 22 patients who completed all scheduled visits without any serious violations during the study period. In both groups, the mean log (urine protein to creatinine ratio) value decreased significantly at 6 months. After 24 weeks, the urinary protein to creatinine ratio decreased by more than 50% in approximately 40% of the patients. The glomerular filtration rate was not significantly altered during the observation period. Conclusions: Losartan decreased proteinuria without decreasing kidney function in patients with IgA nephropathy over 24 weeks. Losartan could be safely employed to reduce proteinuria in this patient population. ClinicalTrials.gov trial registration (NCT0223277)
이화심,Hyesun Shin,박상열,Chang Joon Park 대한화학회 2010 Bulletin of the Korean Chemical Society Vol.31 No.5
Liquid chromatography/mass spectrometry using isotope dilution method has been established as a primary method for the measurement of cortisol in human serum. Verification of this method was accomplished by the participation in Consultative Committee for Amount of Substance-Metrology in Chemistry (CCQM) pilot study. Two levels of cortisol certified reference materials were prepared and certified by the established method. They were used as sample materials for the proficiency testing. The expanded uncertainty in the measurement of cortisol in human serum was approximately 1.2% at 95% confidence level. The results of the proficiency testing showed a good precision among the participants,but some bias to the certified values. This means that commercial field laboratories should keep traceability chain to SI unit through available reference measurement procedures and/or available reference materials.