장기간의 40분 달리기 운동이 비만학생의 혈청 지질 및 아포지단백 대사에 미치는 영향

박철호,권민호,고봉민,박은경,우상헌 東亞大學校附設스포츠科學硏究所 1999 스포츠科學硏究論文集 Vol.17 No.-

The purpose of this study was to investigate the effect of 12 wks before and after running exercise of obsese student in D high school in Pusan city, exercise group(7) performed 12 wks running exercise and control group(7),before and after subjects performed the maximal exercise thest on treadmile's 12 wks running exercise. Through the comparision and analysis of change serum lipids and apoliporotein metabolism, the results of this study were as follows. 1. In 12 wks before and agter running exercise at the rest time,exercise group was found to have a great decrease in TC(8%),TG(29%),LDL-C(7%) and to have a significant in crease in HDL-C(20%),FFA(74%). 2. At the rest, the control group was found to have a little decrease in TG, HDL-C,LDL-C and to have little changes in TC and FFA. 3. In 12wks before and after running exercise at the maximal exercise, the exercise group was found to have a significant decrease in TC(18%),TG(23) and to have a significant in crease in HDL-C(20%),LDL-(25%),FFA(23%) and TG and HDL-C were found to have a significant change. 4. At the maximal exerxcise , were found to have little change in the control group. 5. Apo A-I in the exercise group was found not to have the change signicantly. but to have anincrease 5% at the rest time, 6% at the maximal exercise. And the control group was almost found not to have change. 6. Statically, Apo B in the exercise group was found not to have a signficant change, but to have the increase 12%at the maximal exercise and the control group was found not to have a change.

백서의 실험적 치아이동시 Nitric Oxide Synthetase 발현에 관한 연구

박동권,김은철,김상철 원광대학교 생체재료·매식연구소 1997 원광생체재료·매식 Vol.6 No.1

Nitric oxide(NO) has been reported to be one of the mediators relating to bone remodeling. Nitric oxide is synthesized from L-arguinine by nitric oxide synthetase(NOS), which is largely divided into two groups. One group which is composed of NOS_1 and NOS_3, is dependent of calcium or calmodulin. The other consisted of NOS_2, which is independent of calcium or calmodulin. NOS is thought to be a possible intermediate affecting in the course of tooth movement. This study was designed to evaluate the expression of nitrous oxide synthetase(NOS) in periodontal tissue during the experimental movement of rat incisors, by LSAB(labelled streptavidine biotin) immunohistochemical staining for NOS_2 and NOS_3. Twenty seven Sprague-Dawley rats were divided into a control group(3 rats), and 6 experimental groups(24 rats), to which 75g of force was applied, with helical springs across the maxillary incisors. Rats of experimental groups were sacrificed at 12 hours, 1, 4, 7, 14 and 28 days after force application, respectively. After that, the tissues of the control group and experimental groups were studied immunohistochemically. The results were as follows : 1. In control group, the expression of NOS_3 was rare in gingiva, dentin, periodontal ligament and alveolar bone, and was mild in the capillaries of pulp and intermaxillary suture. And the expression of NOS_2 showed similar pattern to that of NOS_3. 2. There were no differences in the expression of NOS_2 or NOS_3 in dentin, gingiva, cementum, cementoblast and odontoblast, between control and experimental groups, regardless of the duration of the force application. 3. The expression of NOS_3 began to increase at 4 days and showed to the highest degree at 7 days after force application, in the apical region of pressure side of periodontal ligament in experimental groups. 4. The expression of NOS_3 in alveolar bone was rare until 7 days, after which it increased to mild degree at 14 days through 28 days in experimental group. But there was no difference between pressure and tension side of periodontal ligament. 5. The expression of NOS_2 in periodontal ligament was mild from 7 days after force application, regardless of the side of periodontium, which was generally more evident than that of NOS_3. 6. The expression of NOS_2 in alveolar bone increased to mild degree at 14 days after force application, and it was evident in osteoclasts and osteocytes. And the expression of NOS_2 was little more stronger in the tension side than that of pressure side of alveolar bone.

에어로빅운동시 심박수를 이용한 소비에너지량 산출에 관한 연구

박철호,박은경 東亞大學校附設스포츠科學硏究所 1998 스포츠科學硏究論文集 Vol.16 No.-

This study aims to investigate an exercise and to calculate the energy expenditure by the old women in their sixties who take part in the aerobic exercise program of L-Cultural Center in Pusan by using the formula related to their Heart rate and oxygen intake. The conclusion can be obtained from this study as follows: 1. when they do the aerobic exercise, their Heart rate is at 116.8±28.46 beats/min 2. when they do the aerobic exercise, their exercise intensity is at 57.93±21.31%HRmax. 3. when they do the aerobic exercise, their quantity of energy consumpton is at 3.92 Kcal/min, 5758.8 Kcal/day, 3.83MET. 4. there is a high correlation among their Heart rate, respiratory rate, ventilation and other physiological variant factors. Therefore, 50~70%HRmax will be needed in order to improve their sustaining power of whole body. In this respect, judging from their average exercise intensity, they take part in the program of the aerobic exercise in order to improve their ability of an aerobic exercise.

장기간의 40분 달리기 운동이 비만학생의 호흡순환능력과 혈청 지질에 미치는 영향

박철호,고봉민,박은경,우상헌,안민호 동아대학교 스포츠과학연구소 2000 스포츠科學硏究論文集 Vol.18 No.-

The purpose of study was to investigate the effect of 12wks before and after running exercise of obsese in D high school in Pusan city, exercise group(7) performed 12wks running exercise and control group(7), before and after subjects performed the maximal exercise test on treadmill's 12wks running exercise. Through the comparision and analysis of change respiro-circulatory and serum lipids the results of this study were as follows. 1. In 12wks before and after running exercise, physique and body composition of exercise group was found to have a great decrease in %Fat(6%), Fat(kg)(6%), Triceps(7%) and to have a significant in crease in %LBM(6%). 2. Respiro-circulatory Capacity of exorcise group at the maximal exercise, was found to have a great decrese in VE(5%), RR(8%), RQ(5%). 3. In 12wks before and after running exercise at rest time, in seam lipids of exercise group was found to have a great decrease in TC(8%), TG(29%), LDL-C(7%) and to have a significant in crease in HDL-C(20%), FFA(74%). 4. At rest time, the control group was found to have a little decrease in TG, HDL-C, LDL-C and to have little change in TC and FFA. 5. In 12wks before and after running exercise at the maximal exercise, in serum lipids of the exercise group was found to have significant decrease in TC(18%), TG(23%) and to have a significant in crease in HDL-C(20%), LDL-C(25%), FFA(23%) and TG and HDL-C were found to have a significant change. 6. At maximal exercise, was found to have little change in the control group.

환자진료결과연구에 대한 고찰 : 미국 PORT 연구를 중심으로

박은철,김한중,조우현,손명세 한국의료QA학회 1998 한국의료질향상학회지 Vol.5 No.1

Background : In this paper patient outcomes research is going to be reviewed and described, to be compared with relevant studies, and to consider the application in Korea. Methods : We compiled and reviewed the articles and materials related to patient outcomes research especially by PORT(Patient Outcomes Research Team) and rearranged them for seeking the main point and comparing with relevant studies. Results : Patient outcomes research emphasizes patient outcomes as well as conventional clinical outcomes. It is prospective study observing effectiveness in real situation instead of efficacy in ideal condition. Patient outcomes research comprises of 6 fields ; literature review and meta-analysis, use of claims data. decision modeling, outcomes assessment, cost of care, dissemination of research findings. SAA(small-area variations analysis), appropriateness study and clinical practice guideline are connected with patient outcomes research. Conclusion : In view of the fact that current medical policy in Korea is shifting its focus fromaccessibility to the improvement in quality and cost containment, and is stressing patient-based research, patient outcomes research is one direction for which the medicine is accountable and assessable. Considering that the number of patient receiving medical treatment in Korea is higher than the West, patient outcomes research has competitive power as against the West.

백내장 수술환자 진료결과들간의 관계 : 사전 연구를 중심으로 Pilot study

박은철,김한중,홍영재,조우현,손명세,임승정,강형곤,최윤정 한국의료QA학회 1998 한국의료질향상학회지 Vol.5 No.1

Background : This study was done to assess the relationship among multiple patient outcomes of cataract surgery perioperatively, 3-4 months and 12 months after surgery. The patient outcomes include changes in visual acuity(operated eye, better eye), visual function(VF-14), patient satisfaction, subjective satisfaction with vision, and subjective overall health status. Methods : For the assessment of relationship, prospective study was performed with 92 patients who had undergone either one or both eye cataract surgery by 3 ophthalmologists practicing at a university hospital. Patients were interviewed, and clinical data were obtained. Doctors were questioned with self-entered questionnaire forms. Medical record was examined to understand surgery process. The survey was conducted at 4 stages : preoperatively, perioperatively, postoperative 3-4 months, and postoperative 12 months. Results : The correlations within patient outcomes at 4 stages - the visual acuity of operated eye and that of better eye, patient satisfaction and VF-14, subjective overall health status and relative health status as against others - were found to be positively correlated. The change in the visual acuity of operated eye and better eye was correlated with VF-14 as well as with patient satisfaction. The change was also correlated with overall health status. However, the correlations between variables were decreased as the postoperative period got longer. Conclusion : As for the postoperative clinical patient outcomes, VF-14 is acted to linker between visual acuity - clinical outcomes and overall health status - endpoint outcomes. Therefore, VF-14 is the index of patient-sided and disease-specific outcome for cataract surgery.

복강경 검사로 진단한 결핵성 복막염 1례

박민경,서원석,박재옥,김창휘,고은석,임철완 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Tuberculous peritonitis is discovered from sixty to ninty percent of pulmonary tuberculosis patients. Clinical symptoms are nonspecific such as mild fever, weakness and malaise but show tenderness in right lower abdomen and abdominal distension. Diagnosis is confirmed by laparoscopic and pathologic findings. We report a case of tuberculous peritonitis in an 11-year-old boy who was hospitalized because of abdominal distension with pain on right lower abdomen which had developed one day before he came to hospital. Chest X-ray showed pleural effusion on both sides. We did laparoscopic examination and observed diffuse nodular infiltration. In biopsy specimen we observed osseous granuloma and acid-fast bacilli in AFB stain.

의료전달체계 개선의 방향과 전략

박은철 건강보험심사평가원 2021 HIRA RESEARCH Vol.1 No.1

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승강대 운동이 비만고등학생의 혈청 지질 및 아포지단백 대사에 미치는 영향

박철호,고봉민,박은경,우상헌,안민호 동아대학교 스포츠과학연구소 2000 스포츠科學硏究論文集 Vol.18 No.-

The purpose of this study was to investigate the effect of 12 wks before and after step test of obsese student in D high school in Pusan city, exercise group(7) performed 12 wks step test and control group(7), before and after subjects performed the maximal exercise thest on treadmile's 12 wks step test. Through the comparision and analysis of change serum lipids and apolipoprotein metabolism, the results of this study were as follows. 1.In 12 wks before and after step test at the rest time, exercise group was found to have a increase In TC(12.7%), TG(9.76%), LDL-C(13.8%) and to have a significant increase in HDL-C(11.3%), FFA(96.8%). 2.At the rest, the control group was found to have a little increase in TG(9.2%) and HDL-C(6.7%), and to have a significant increase in TC(9.2%), LDL-C(8.9%) and FFA(7.5%). 3.In 12 wks before and after step test at the maximal exercise, the exercise group was found to have a significant increase in TC(5.6%), HDL-C(20.2%) and FFA(54.3). 4.At the maximal exercise, were found to have a significant increase in TC(9.7%) and LDL-C(9.9%) in the control group. 5.In 12 wks before and after step test at the maximal exercise, the exercise group was found to have a significant increase in Apo A-I(8.0%). 6.Statistically, At the maximal exercise, were found to have a significant increase in Apo B(7.8%).

조기위암의 임상적 연구

박태준,양은수,류종철,박태군,이희승,신원창,이진호,김관엽 인제대학교 1994 仁濟醫學 Vol.15 No.1

1989년 9월부터 1993년 7월까지 인제대학교 의과대학 상계백병원에서 실시한 위내시경 소견이 조기위암이며 내시경 직시하 생검결과 선암으로 판명되어, 근치적 위절제술을 시행받은 23명의 환자에서 임상적 특징을 알아보고, 문헌고찰과 함께 보고하는 바이다. The incidence and mortality rate of stomach cancer ranks well ahead of all malignancies in Korea. The prognosis is excellent in early gastric cancer of which the overall 5 years survival rate of 85∼95% is comparative with that of advanced gastric cancer of 15∼49%. So early detection with very sensitive mordality of gastroscope and surgery is the only premise to decrease the mortality rate of gastric cancer. This report deals with the clinical aspects of 23 cases of early gastric cancer, which were confirmed with histopathologic examination of resected stomach during the 4 years from September 1989 to July 1993 at Sanggye Paik hospital, Seoul, Korea. Out of 23 cases of early gastric cancer, 14 cases were male, 9 cases were female, and the male to female ratio was 1.6 : 1. The most common type of early gastric cancer was talc type(43.5%), IIc and its combined type comprised most of them(87.0%). The most prevalent sloe of lesion was gastric angle(43.5%) and the most common direction was lesser curvature(73.9%) 19 cases of 23(78.3%) were between 1∼3cm in size, and there was no statistical significance between the size of the lesion and lymph node metastasis. Of the 9 cases with mucosal lesion, there were 2 cases with lymph node metastasis(22.2%), but 7cases(50.0% ) of 14 cases with submucosal lesion presented lymph node metastasis. Diagnostic accuracy of endoscopy on detection of early gastric cancer was 17 cases(73.9%) of total 23 cases in our study. As with other report, histopathulogic examination of resected stomach revealed adenocarcinoma, tubular type as the most common type. Frequent complaint of patients with early gastric cancer was epigastric pain(65.2%), and duration of the symptom was less than 12 months in 17 cases(73.1%) of 23 patients with early gastric cancer.