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      • KCI등재

        Marketer-Generated Content Sharing Among Social Broadcasting Users: Effects of Intrinsic Motivations, Social Capital and the Moderating Role of Prevention Focus

        Li, Yuhao,Wang, Kanliang The Korea Society of Management Information System 2015 Asia Pacific Journal of Information Systems Vol.25 No.4

        Social networking services provide individuals with an easy approach for exchanging messages with others based on interpersonal relationships. However, why individuals spread marketer-generated content (MGC) in their online social circles remains unclear. Therefore, we develop a theoretical model to examine how social capital, intrinsic motivations, personal perceptions, past behavior, and personal traits influence MGC sharing behavior of social media users in micro-blogging context. Data collected from 319 social networking users support the proposed model. The results from partial least squares analyses show that enjoyment, perceived control, and outcome expectations are significant indicators of individual's MGC sharing intention in the social broadcasting environment. Results also suggest that social capital, users' intention, and past behavior positively influence the MGC sharing behavior of users. Moreover, individual prevention pride exhibits a significant interaction effect on the relationships between users' MGC sharing and its antecedents. Implications for research and practice are discussed.

      • KCI등재
      • KCI등재

        Synthesis, Crystal Structure and Fungicidal Activities of New Type Oxazolidinone-Based Strobilurin Analogues

        Yuhao Li,Rui Liu,Zhangwei Yan,Xiangning Zhang,Hongjun Zhu 대한화학회 2010 Bulletin of the Korean Chemical Society Vol.31 No.11

        A series of oxazolidinone-based strobilurin analogues were efficiently synthesized by the reaction of 3-(2-bromomethylphenyl)oxazolidin-2-one with 1-substituted phenyl-2H-pyrazolin-3-one. Their structures were confirmed and characterized by 1H-NMR, 13C-NMR, elemental analysis, and mass spectroscopy. In addition, the crystal structure of the target compound 3-(2-((1-phenyl-2H-pyrazol-3-yloxy)methyl)phenyl) oxazolidin-2-one was determined by single crystal X-ray diffraction. The bioassay results of these compounds indicated that some of the oxazolidin-2-one derivatives containing N-substituted phenyl 2H-pyrazol ring exhibited potential in vivo fungicidal activities against M. grisea at the dosage of 1 g L‒1.

      • SCOPUSKCI등재

        Synthesis, Crystal Structure and Fungicidal Activities of New Type Oxazolidinone-Based Strobilurin Analogues

        Li, Yuhao,Liu, Rui,Yan, Zhangwei,Zhang, Xiangning,Zhu, Hongjun Korean Chemical Society 2010 Bulletin of the Korean Chemical Society Vol.31 No.11

        A series of oxazolidinone-based strobilurin analogues were efficiently synthesized by the reaction of 3-(2-bromomethylphenyl) oxazolidin-2-one with 1-substituted phenyl-2H-pyrazolin-3-one. Their structures were confirmed and characterized by $^1H$-NMR, $^{13}C$-NMR, elemental analysis, and mass spectroscopy. In addition, the crystal structure of the target compound 3-(2-((1-phenyl-2H-pyrazol-3-yloxy)methyl)phenyl) oxazolidin-2-one was determined by single crystal X-ray diffraction. The bioassay results of these compounds indicated that some of the oxazolidin-2-one derivatives containing N-substituted phenyl 2H-pyrazol ring exhibited potential in vivo fungicidal activities against M. grisea at the dosage of $1\;g\;L^{-1}$.

      • KCI등재

        Polymer composite microspheres loading 177Lu radionuclide for Interventional Radioembolization therapy and Real-time SPECT imaging of Hepatic Cancer

        Liu Xiao,Yuhao Li,Ruiman Geng,Lihong Chen,Peng Yang,Mingyu Li,Xia Luo,Yuchuan Yang,Lin Li,Huawei Cai 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00

        Background Transarterial radioembolization (TARE) with 90Y-labeled glass and resin microspheres is one of the primary treatment strategies for advanced-stage primary and metastatic hepatocellular carcinoma (HCC). However, difficulties of real-time monitoring post administration and embolic hypoxia influence treatment prognosis. In this study, we developed a new biodegradable polymer microsphere that can simultaneously load 177Lu and MgO nanoparticle, and evaluated the TARE therapeutic efficacy and biosafety of 177Lu-PDA-CS-MgO microspheres for HCC treatment. Methods Chitosan microspheres were synthesized through emulsification crosslink reaction and then conducted surface modification with polydopamine (PDA). The 177Lu and nano MgO were conjugated to microspheres using active chemical groups of PDA. The characteristics of radionuclide loading efficiency, biodegradability, blood compatibility, and anti-tumor effectwere evaluated both in vitro and in vivo. SPECT/CT imaging was performed to monitor bio-distribution and bio-stability of 177Lu-PDA-CS-MgO after TARE treatment. The survival duration of each rat was monitored. HE analysis, TUNEL analysis, immunohistochemical analysis, and western blot analysis were conducted to explore the anti-tumor effect and mechanism of composited microspheres. Body weight, liver function, blood routine examination were monitored at different time points to evaluate the bio-safety of microspheres. Results The composite 177Lu-PDA-CS-MgO microsphere indicated satisfactory degradability, biocompatibility, radionuclide loading efficiency and radiochemical stability in vitro. Cellular evaluation showed that 177Lu-PDA-CS-MgO had significant anti-tumor effect and blocked tumor cell cycles in S phase. Surgical TARE treatment with 177Lu-PDACS- MgO significantly prolonged the medial survival time from 49 d to 105 d, and effectively inhibited primary tumor growth and small metastases spreading. Moreover, these microspheres indicated ideal in vivo stability and allowed real-time SPECT/CT monitoring for up to 8 weeks. Immunostaining and immunoblotting results also confirmed that 177Lu-PDA-CS-MgO had potential in suppressing tumor invasion and angiogenesis, and improved embolic hypoxia in HCC tissues. Further evaluations of body weight, blood test, and pathological analysis indicated good biosafety of 177Lu-PDA-CS-MgO microspheres in vivo. Conclusion Our study demonstrated that 177Lu-PDA-CS-MgO microsphere hold great potential as interventional brachytherapy candidate for HCC therapy. Graphical Abstract Polymer composite microspheres loading 177Lu radionuclide and MgO nanoparticles for interventional radioembolization therapy and real-time SPECT imaging of hepatic cancer.

      • KCI등재

        Adaptive robust control of active magnetic bearings rigid rotor systems

        Yuhao Xu,Xiaoyuan Wang,Mingxin Liu,Na Li,Tian Yu 전력전자학회 2023 JOURNAL OF POWER ELECTRONICS Vol.23 No.6

        Aiming at the problems of diffi cult decoupling, complex controller models, and poor disturbance rejection capability caused by the inherent nonlinear and strong coupling characteristics of the active magnetic bearing (AMB), an adaptive H-infinity robust control (AHRC) method is proposed in the AMBs-rigid rotor system. The proposed method combines the active disturbance rejection control (ADRC) with the robust control to achieve stable operation of the AMBs-rigid rotor system under high-speed conditions. First, a four-degree-of-freedom (4-DOF) AMBs-rigid rotor model was established and transformed into a one-degree-of-freedom (1-DOF) model for the design of the robust controller, which weakens the coupling effect between each of the degrees of freedom (DOF). Then the multi-objective non-dominated sorting genetic algorithm II (NSGA-II) was used to fi nd the relative optimal weighting function value of the H-infinite robust control (HRC), which solved the difficulties in the design of the robust controller for known controlled system models. In addition, by combining the optimized H-infi nity robust controller with the original error feedback control rate in the ADRC, the proposed AHRC retains the strong robustness of the HRC and the decoupling capability of the ADRC, which improves the tracking performance and anti-disturbance performance of the controlled system. Simulation and experimental results verify the effectiveness of the proposed method.

      • KCI등재후보

        US-Vietnam Comprehensive Partnership: Achievements, Problems and Development Trends

        Gen Li,Yuhao Wang,Yuchun Song 한국국회학회 2021 한국과 세계 Vol.3 No.1

        In recent years, the bilateral relations between the United States and Vietnam have shown a momentum of rapid development. The year 2020 marks the 25th anniversary of the normalization of bilateral relations between the two countries. Through sorting out the effects, problems and development trends of the comprehensive partnership between the two countries, this paper discusses the factors restricting the development of the bilateral relations, and then analyzes the prospects of the development of the US-Vietnam relations. The United States and Vietnam have a number of strategic convergence points to deepen cooperation, but at the same time, the two countries still face challenges in ideology, political system and other aspects. In the future, it is possible for the US-Vietnam relationship to continue to strengthen. On the one hand, Vietnam will strengthen bilateral relations with the US and implement multilateralism diplomacy to contain China. On the other hand, Vietnam will avoid stimulating China and stabilize its relations with China.

      • Migrant Workers’ Choice of Participating in Public Health Insurance

        Xiao Taixi,Li Yuhao,Yang Yi-fan 연세대학교 빈곤문제국제개발연구원 2011 Journal of Poverty Alleviation and International D Vol.2 No.2

        The objective of this article is to understand the factors that may affect the attitudes of the migrant workers toward the issue of joining the health insurance system. Three hundred twenty-three migrant workers were sampled and surveyed; R 2.12.2 was used to analyze the data by exerting the logistic method. It was found that migrant workers from different areas of the industry have different attitudes with respect to the medical insurance system, while the family factor has significantly affected these attitudes. To fulfill the policy of providing medical insurance to migrant workers, both group and individual factors need to be considered.

      • SCIESCOPUSKCI등재
      • Structure learning of exponential family graphical model with false discovery rate control

        Liu Yanhong,Zhang Yuhao,Li Zhonghua 한국통계학회 2023 Journal of the Korean Statistical Society Vol.52 No.3

        Probabilistic graphical models enjoy great popularity in a wide range of domains due to their ability to model the conditional dependency relationships among random variables. This paper explores the structure learning for the exponential family graphical model with false discovery rate (FDR) control. Most existing FDR-con-trolled structure learning procedures have been designed for the Gaussian graphical model (GGM). A systematic approach for more general exponential family graphical models is still lacking. In this paper, we introduce a unified procedure to learn the structure of the exponential family graphical model with FDR control utilizing the symmetrized data aggregation (SDA) technique via sample splitting, data screening, and information pooling. We show that our method controls FDR asymptotically under some mild conditions. Extensive simulation results and two real-data examples validate the effectiveness of our method.

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