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Shiqi Liu,Huanling Wang,Weiya Xu,Zhichao Cheng,Zhipeng Xiang,Wei-Chau Xie 대한토목학회 2020 KSCE JOURNAL OF CIVIL ENGINEERING Vol.24 No.11
Soil-rock mixture is a widely distributed geological material in mountainous regions, where slope stability is an important issue. To investigate the influence of rock on slope stability, firstly, rocks in SRM are generated and then SRM slope models are simulated based on the finite difference method (FDM). The impact of various characteristics of rocks on slope factor of safety (FOS) is studied systematically by using the reduced strength method. The characteristic of rock considered include rock content, number of rock edges, aspect ratio, rock size and inclination of rock. The simulations indicate that increasing the rock content can prevent the development of high strain region and improve slope stability. However, the aspect ratio of rock has negligible impact on the mean value of FOS. For slopes with 45o slope angle, rocks with 45o angle of inclination result in smooth potential sliding surface, whereas rocks with 135o angle of inclination lead to more tortuous potential sliding surfaces. Statistical indices are utilized to analyze the results of numerical modelling.
Shiqi Liu,Shuxun Sang,Jingsheng Ma,Xin Wang,Yi Du,Tian Wang 한국지질과학협의회 2019 Geosciences Journal Vol.23 No.1
Pore connectivity is an important property of coal. To explore the connectivity of pore-fractures in terms of macropores and mesopores in high-rank coal, two coal samples collected from the coal seam #3 in the southern Qinshui basin were selected. A pore-fracture network model of high-rank coal on the nanometer (10–100 nm) to micrometer (0.1–10 μm) scale is constructed, and key parameters are extracted using the 3D (three-dimensional) digital spatial characterization based on 3D scanning with FIB-SEM (Focused Ion Beam Scanning Electron Microscopy). Then, the connectivity of the pore-fractures and the contribution of pores with different genetic types to the connectivity of the high-rank coal are confirmed. The results show that the pores and throats of high-rank coal in coal seam #3 in the southern Qinshui basin are very narrow, with predominant mesopores < 50 nm in width. The tortuosity of the coal samples is low, an the cross-section is predominantly square and triangular in shape, which means that the capillary resistance is small. The connectivity of the pores is poor, and mesopores play an important role in the pore connectivity. Linear differential shrinkage pores are the main connected pores on the nanometer scale and communicate with irregularly rounded and elliptic differential shrinkage pores, secondary pores, and mineral pores. The types and contents of the minerals in coals determine the morphological characteristics and degree of development of the differential shrinkage pores, and have an important influence on the pore connectivity in high-rank coal. The content of quartz determines the degree of development of the linear differential shrinkage pores, and is the primary reasons for the differences in the connectivity of the two samples.
Shiqi Liu,Xiangting Hou,Chengze Yu,Xiangrui Pan,Junhao Ma,Guocheng Liu,Chengzhi Zhou,Yanjun Xin,Qinghua Yan 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.115 No.-
Among the bromine flame retardants, tetrabromobisphenol A (TBBPA) is a highly effective flame retardantthat can be used as both reactive and additive. However, the synthesis reaction of TBBPA has alow conversion rate and many brominated phenolic organics. Therefore, there is an urgent need toremove brominated organic pollutants produced in the process of producing flame retardants to reducethe harm to the environment and human beings and to reduce production costs. In this study, an efficientprocess was developed to treat the wastewater and waste residue generated in TBBPA production process,realizing its harmless and resource utilization. In the resource utilization system, through the ingeniousdesign of solution mixing, precipitation separation, three-effect evaporation and concentration,valuable substances were extracted to realize the recovery and reuse of wastewater. In the harmless utilizationprocess of hazardous waste residue, through high-temperature pyrolysis at 500 C for 2 h afteroptimization with hypoxia-hyperoxia atmosphere modulation, it can avoid the production of dioxinsand carbon black, effectively remove the organic impurities, realize the harmlessness and obtain highqualitysodium sulfate. This paper aims to propose a simple, efficient and feasible utilization system,including the three major technological processes of TBBPA production, integrated wastewater treatmentand optimized the harmless treatment of waste residue to obtain sodium sulfate, so as to realize TBBPAgreen production. Compared with the traditional TBBPA synthesis system, wastewater and waste residuetreatment processes, the TBBPA quality is increased by 2 % and the economic cost is reduced by 10 %,which is of great significance to the development of the industry.
Liu, Tao,Peng, Jian,Xiong, Yuanzhu,Zhou, Shiqi,Cheng, Xuehui Asian Australasian Association of Animal Productio 2002 Animal Bioscience Vol.15 No.2
Seventy-four piglets were used to investigate the effects of dietary glutamine (Gln) and glutamate (Glu) on the mucosal structure and active absorption of small intestinal, DNA and RNA concentrations of skeletal muscle tissue in piglets during d 28 to 42 of age. Postweaning piglets were fed for 14 d corn- and soybean meal-based diets supplemented with 0.0 or 1.0% L-Gln or L-Glu. On d 7 and 14 postweaning, pigs' small intestinal sections and longissimus dorsi were collected, at the same time, the D-xylose absorption test was conducted. The results suggested that in comparison to control piglets, jejunal atrophy during the first week postweaning was prevented by the glutamine and glutamate supplementation (1%) and the capability of small intestine to absorb Dxylose was improved. Furthermore the RNA concentration in skeletal muscle tissue was increased. These results provide an experimental basis for use of glutamine and glutamate on alleviating the weaning stresses and improving piglets' growth performance.
Magnetic Integration of EMI filter for Grid-Connected Voltage-Source Inverters
Shiqi Jiang,Yitao Liu,Jianchun Peng,Hui Jiang 전력전자학회 2019 ICPE(ISPE)논문집 Vol.2019 No.5
The magnetic integration method of single-stage and multi-stage electromagnetic interference (EMI) filter was proposed with EE and EIE-type cores for single-phase grid-connected voltage-source inverter (VSI). Common mode (CM) and differential mode (DM) chokes were all integrated into a single magnetic core unit. The effectiveness of integrated single-stage EMI filter (ISSEF) and multi-stage EMI filter (IMSEF) has been verified by simulation and experiments. Taking a 500 W single-phase inverter as an experiment platform, the conducted EMI noise and core temperature distribution were presented. The EMI filter with integrated structure can significantly reduce system volume with satisfied EMI suppression ability.
Cong Yuan,Lisha Zhu,Shiqi Liu,Du Zunling,He Li 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.2
The flow dynamics of the cavitating jet through poppet valves inevitably suffers from the influence of varying openness, but the relevant mechanism remains unclear. Hence, the present study conducts a numerical study on the cavitating flow phenomenon inside poppet valves with two valve seat structures, in order to examine the flow mechanisms underlying varying cavitation phenomenon at different openness. According to the results, the overall cavitation distribution as well as the morphology feature follows a similar pattern due to the same inception mechanism irrelevant of the openness amount. However, examination of the dynamic behaviors confirms discernable variation in 2 coupling effects between flow instability and cavitation. The flow separation at the poppet trailing edge produces non-cavitation flow instability at 0.4 mm openness and attached cavitation at 0.8 mm, which amalgamate with upstream-shed vortex cavitation. The stably attached cavitation within the chamfered groove at 0.4 mm, as the source of non-cavitation flow instability, and the detached cavitation at 0.6 and 0.8 mm openness produce vortex cavitation at the free shearing side. The substantial variation in these two coupling effects contributes sensibly to the increase in the overall cavitation intensity. Meanwhile, the weakened coupling effect between the free shearing vortex and wall shearing vortex, as a consequence of increased potential core thickness at larger openness, leads to the attenuated vortex cavitation at the wall poppet side. Additionally, the vortex cavitation at free shearing side has a larger size in the chamfered valve seat case, due to the coupling of shed flow instability with the Kelvin-Helmholtz instability. As a conclusion, the inception mechanism for the cavitation remains unchanged with openness, while the difference in flow instabilities as well as the associated coupling effects with cavitation contributes to the variation in cavitation intensity.
MicroRNA-576-3p Inhibits Proliferation in Bladder Cancer Cells by Targeting Cyclin D1
Liping Xie,Zhen Liang,Shiqi Li,Xin Xu,Xianglai Xu,Xiao Wang,Jian Wu,Yi Zhu,Zhenghui Hu,Yiwei Lin,Yeqing Mao,Hong Chen,Jindan Luo,Ben Liu,Xiangyi Zheng 한국분자세포생물학회 2015 Molecules and cells Vol.38 No.2
MicroRNAs (miRNAs) are small, endogenous RNAs that play important gene-regulatory roles by binding to the imperfectly complementary sequences at the 3 -UTR of mRNAs and directing their gene expression. Here, we first discovered that miR-576-3p was down-regulated in human bladder cancer cell lines compared with the non-malignant cell line. To better characterize the role of miR-576-3p in bladder cancer cells, we over-expressed or down-regulated miR-576-3p in bladder cancer cells by transfecting with chemically synthesized mimic or inhibitor. The overexpression of miR-576-3p remarkably inhibited cell proliferation via G1-phase arrest, and decreased both mRNA and protein levels of cyclin D1 which played a key role in G1/S phase transition. The knock-down of miR-576-3p significantly promoted the proliferation of bladder cancer cells by accelerating the progression of cell cycle and increased the expression of cyclin D1. Moreover, the dual-luciferase reporter assays indicated that miR-576-3p could directly target cyclin D1 through binding its 3 -UTR. All the results demonstrated that miR-576-3p might be a novel suppressor of bladder cancer cell proliferation through targeting cyclin D1.