한국전통 식품의 원료인 메주와 누룩에서 분리된 접합균에 대한 연구

유기원,성창근,이상선,유진영 충남대학교 생물공학연구소 1998 생물공학연구지 Vol.6 No.-

The fungal isolates of Mucorales, directly collected from Korean traditional raw materials of Nuruk (raw material for Korean rice wine) and Meju (raw material for Korean soysauces), were compared with those of Rhizopus oryzae purchased. The fungal isolates of Rhizopus, Mucor, and Absidia mostly identified as based on the morphological observations, were evaluated with the PCR-polymorphic bands. The PCR-polymorphic bands of the genomic DNA reacted with the primers of OPD series tenmer were various, but showed averaged 4 to 6 in the agarose-electrophoresis. The dissimilarity coefficient (DC) between two isolates were compared by the cluster analysis, dendrogams and polar ordinations. The isolates of R. oryzae known showed several groupings within the lower value of DC and were divided to two groups of amylo-process and other fungi with other purposes. The isolates unidentified were identified by the DC made of this results. Taxonomy of these isolates made by the morphological observations were consistent with those resulted above in most case but not in all aspects. More works were needed with the isolates known for detail informations of Mucorales.

ESO 기법을 이용한 컴플라이언트 메커니즘 설계

이원구,박재용,김상락,유진식,한석영 한국공작기계학회 2008 한국공작기계학회 춘계학술대회논문집 Vol.2008 No.-

A compliant mechanism is a mechanism that produces its motion by the flexibility of some or all of its members when the input forces are applied. Whereas the topology optimization based on homogenization and SIMP parameterization has been successfully applied for compliant mechanism design, an ESO approach has not been considered yet for the optimization of these types of systems. This work presents a modified version of the evolutionary structural optimization (ESO) Procedure for its application in topology optimization of compliant mechanisms, It will be shown that an additive version of this method must be adopted in order to achieve the optimum design, since the traditional ESO method's element removal technique is not efficient in this case. The methodology is based on a mutual energy concept for formulation of flexibility and the ESO method. A multi-objective optimization problem is formulated as an application of compliant mechanism design. The procedure has tested in several numerical applications and benchmark examples to illustrate and validate the approach.

외상 환자에서 의식소실 유무와 외상후 스트레스 장애의 유병율, 증상 양상, 우울 및 불안에 관한 연구

이유진,연규월,우행원,김영철,임원정 大韓神經精神醫學會 2002 신경정신의학 Vol.41 No.4

연구목적 : 본 연구에서는 의식 소실 유무에 따른 외상후 스트레스 장애 유병율 및 증상, 우울, 불안 증상을 알아보기 위해 외상을 당한 환자를 의식 소실이 있었던 환자군과 의식 소실이 없었던 환자군으로 구분하여 두 집단의 외상후 스트레스 장애의 유병율, 증상 및 불안 정도를 비교해보고자 하였다. 방 법 : 사고를 당하고 1달 이상 경과한 환자 120명(남자 69명, 여자 51명)을 대상으로 하였다. 대상군을 의식 소실 유무에 따라 소실군과 비소실군으로 구분하고 사회인구학적 변수, 사고 당시 의식 소실의 유무, 의식 소실 시간, 사고의 종류, 사고에 대한 기억, 사고의 심각도, 손상 심각도 점수(Injury Severity Score)를 조사하여비교하였다. 또한 외상후 스트레스 장애 척도(Clinician Adminstered PTSD Scale), Beck의 우울증 척도(Beck Depression Inventory), 상태 특성 불안처도- Ⅰ, Ⅱ(State Trait Anxiety Inventory- Ⅰ, Ⅱ)를 이용하여 조사하여 두 군 사이의 외상후 스트레스 장애유병율 및 증상, 우울, 불안 정도를 비교하였다. 결 과 : 통 연구 대상자 120명중 의식 소실이 있었던 환자군(소실군)은 56명(46.7%)이었고 의식 소실이 없었던 환자군(비소실군)은 64명(53.3%)이었다. 총 대상자 120명중 30명(25%)이 외상후 스트레스 장애로 진단되었으며 소실군 56명중 17명(30.4%)이 비소실군 64명중 13명(20.3%0이 각각 외상후 스트레스 장애로 진단되었으나 두 군간의 차이는 통계적으로 유의하지 않았다(x^2=1.607, P>0.05). 외상후 스트레스 장애 증상 척도에서는 소실군에서 사고에 대한 기억 상실, 흥미 상실, 이탈, 감정 둔마, 수면자애, 예민함, 집중력 감소 증상의 빈도가 유의하게 높았다(P<0.05). 비소실군에서느 반복적인 회상과 놀람 반응 빈도가 유의하게 높았다(p<0.05). Beck의 우울증 척도 점수는 소실군에서 38.8±8.8, 비소실군에서 31.0±7.9로 의식 소실을 보고한 환자군의 점수가 유의하게 높았으며(t=-3.16, 0<0.05) 상태 특성 불안 척도-I, II는 소실군에서 각각 44.5±3.3, 44.6±3.9, 비소실군에서 각각 42.9±3.0, 42.3±3.4로 소실군의 점수가 유의하게 높았다(t=-2.75, p<0.05, t=-3.38, p<0.05). 결 론 : 사고 당시 의식 소실이 없었던 환자군과 비교하여 외상후 스트레스장애가 비슷한 빈도로 진단되며 의식 소실이 외상후 스트레스 장애의 발생에 유의한 영향을 미침은 물론 불안 및 우울에도 유의한 영향을 미친다고 할 수 있다. Objectives :This study investigated PTSD prevalence, symptoms, depressed mood and anxiety, comparing two groups of the patients in trauma ; one who had experienced the loss of consciousness(group "A" here after) and the other group of patients who had not(group "B" here after). Method : subjects were 120 patients(age18-66) who had received trauma(traffic accident, fall down) more than 1 month. Before they consisted of 56 patients who had experienced the loss of the consciousness(46.7%) and 64 who had not(53.3%). Men were 69 and women were 51. Clinician administered PTSD Scale, Beck Depression Inventory, State Trait Anxiety Inventory-I, II were administered. The factors such as sociodemographic variables, unconsciousness at the time of trauma, memory about tranmatic accidents were considered. Result : Out of 120 subjects, 30 patients(25%) were diagnosed as PTSD : 17 from 56(30.4%) and 13 from 64(20.3%) were found in the group "A" and "B" respectively. Prevalence of PTSD was higher in the group "A" showed significant difference between two groups(x^2=1.607,p>0.05). The CAPS of group "A" showed significantly high frequency in the loss of interest, detachment, restricted affect, sleep difficulty, irritability/anger. concentration difficulty(p<0.05), while the group "B" scored high in intrusive recall and increased startle. The scores of BDI, STAI-I, II were significantly higher in the group "A"(t=-3.16, p<0.05)(t=-2.75, p<0.05, t=-3.38, p<0.05). Conclusion : PTSD was mre frequent and depressed mood and anxiety appeared more often in the group qho experienced the loss of consciousness. Thus the loss of the consciousness at the time of trauma prones of the aevelopment PTSD and symptom of aepression and anxiety.

구개주름의 형태형성과 Retinoic Acid로 유발된 이상

김혜진,신웅기,권오유,이영호,김원식 충남대학교 의과대학 지역사회의학연구소 1996 충남의대잡지 Vol.23 No.2

Morphogenesis of palatal rugae and retinoic acid-induced anomalies, numerical and pattern disruptions, were studied to know the mechanism of normal rugae formation and the relations between these disruptions and retinoic acid teratogenecity. Sprague-Dawley rats and all trans retinoic acid of Sigma Chemicals were used in this experiment. Retinoic acid was administered at gestational day 8, 9, 10, 11, and 12 by the dose of 60mg/kg 80mg/kg 100mg/kg and 120mg/kg respectively per orally. At the gestational day 17.5, the rats were sac rificed under ether anesthesia and removed entire uterine horns into the saline-filled Petri dish. Congenital anomalies on the head and palatal rugae were observed with stereoscope. and light and transmission electron microscopic observation were performed to investigation histologic changes of the rugal epithelium and mesenchyme after retinoic acid treatment. The results were as follows; 1. Retinoic acid-induced congenital anomalies in this experiment were exencephaly and hydrocephalus in gestational day 8 and 9 groups, and cleft palate in gestational day 9 and 10 groups, and the number of anomalies was increased dose dependently. 2. Severe numerical variation and pattern disruptions such as division, medial and lateral fusion, cross, bifid rugae and rugal papillae were found on the gestational day 9 and 10 groups, and the relation between the retinoic acid teratogenecity and the numerical and pattern disruptions of the rugae were very close. 3. On TEM observation, the basal laminae under the rugal epithelium were absent at many areas and the filopodiae of the epithelial cells protruded into the underlying mesenchyme. According to the above results, it is considered that the mesenchymal cells of palatal shelf migrate into the designated areas of epithelium through the basal lamina, proliferate rapidly and form the rugae. Retinoic acid may inhibit the proliferation and migration into the epithelium of mesenchymal cells and the incompatibility between the growth of palatal shelf and the slowed speed of mesenchymal cells migration into the epithelium will leads the numerical and pattern disruptions of the rugae. And the relation between the teratogenecity of the retinoic acid and the numerical and pattern disruptions of the rugae was considered to be very close.

한국무예의 발전동향과 과제 및 전망

서충진,강유원,김이수 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.20 No.1

Where is the Oriental martial arts going in these days? Can it be separated with sports or physical education to get its own region? To get a solution from these questions, there are three parts of studies of the possible trends on Korean martial arts such as the actual conditions on educating coach of martial arts, the research about thesis of martial arts, and the actual conditions of related journals. For the conclusion, the following five solutions could be shown. At first, there should be a general modification on processing of educating the martial arts coach. 1. Expanding the items of martial arts can raise the level of coach's educating quality based on the curriculum, the contents, and the variety programs. 2. Martial arts sports, ordinary martial arts, and traditional martial arts must be unifiable and simple to develope its problems. 3. the importance of traditional martial arts and the qualified test of its coach must have a mutual preservation and maintenance through being related with each other between martial arts' each items. Second, it's necessary to train the martial arts with required elements of the recognition, the theory, the existence and the philosophy. Third, it's necessary to take shape of pyramidical structure through the long term policy of training martial arts. Forth, variety events of martial arts should be held regularly from the government. At last, it's necessary to expand the martial arts region and make variety activities from related academies or institutes.

품질이 보증되는 객체지향 시스템 개발을 위한 ISO-15504(SPICE) 프로세스 연구

정유진,방상원,방만원 木浦大學校 工業技術硏究所 1998 工業技術硏究誌 Vol.8 No.-

ISO Quality standards increase S/W operating efficiency with standardization and quality assessment. And OO programming technologies increase S/W operating efficiency with natural development methodology. We propose OMT process', that is combined with ISO-15504(SPICE) and OMT, framework and lifecycle and planning phase's task. OMT process will help S/W development more easy.

레진 시멘트를 이용한 레진 파이버 강화 레진포스트의 치근 상아질에 대한 미세인장결합강도

김진우,유미경,이세준,이광원 大韓齒科保存學會 2003 Restorative Dentistry & Endodontics Vol.28 No.1

Object The purpose of this study were to evaluate the microtensile bond strength of resin fiber reinforced post to radicular dentin using resin cement according to various dentin surface treatment and to observe the interface between post and root dentin under SEM. Material and Method A total 16 extracted human single rooted teeth were used. A lingual access was made using a #245 carbide bur in a high-speed handpiece with copious air water spray. The post space was mechanically enlarged using H-file(up to #60) and Gates Glidden bures(#3). This was followed by refining of the canal space using the calbrating drill set provided in ER Dentinpost(GEBR, BRASSELER GmbH&Co. KG). The 16 teeth were randomly distrubuted into 4 group of 4 teeth. Group 1 teeth had their post space prepared using 10% phosphoric acid as root canal surface treatment agent during 20s. The canal was then rinsed with saline and dried with paper point. Group 2 teeth had their post space prepared using 3% NaOCI as root canal surface treatment agent during 30min. The canal was then rinsed with saline and dried with paper point. Group 3 teeth had their post space prepared using 17% EDTA as root canal surface treatment agent during 1min. The canal was then rinsed with saline and dried with paper point. Group 4 teeth had their post space prepared using 17% EDTA as root canal surface treatment agent during 1 min. After rinsing with saline, the canal was rinced 10ml of 3% NaOCI for 30min. After drying with paper point, the post(ER Dentinpost, GEBR, BRASSELER GmbH&Co. KG) was placed in the treated canals using resin cement. Once the canal was filled with resin cement(Super bond C&B sunmedical co. Ltd.), a lentulo was inserted to the depth of the canal to ensure proper coating of the root canal wall. After 24 hours, acrylic resin blocks(10·15·50mm) were made. The resin block was serially sectioned vertically into stick of 1·1mm. Twenty sticks were prepared from each group. After that, tensile bond strengths for each stick was measured with Microtensile Tester. Failure pattern of the specimen at the interface between post and dentin were observed under SEM. Results 1. Tensile bond strengths(meen±SD) were expressed with ascending order as follows ; group 4, 12.52±6.60 ; group 1, 7.63±5.83 ; group 2, 4.13±2.31 ; group 3, 3.31±1.44. 2. Tensile bond strengths of Group 4 treated with 17% EDTA +3%NaOCI were significant higher than those of group 1, 2 and 3 (p<0.05). 3. Tensile bond strengths of Group 1 treated with 10% phosphoric acid were significant higher than those of group 2 (p<0.05). Tensile bond strengths of Group 4 treated with 17% EDTA +3% NaOCI was significant higher than those of other groups.

학령전기 아동의 글씨 쓰기에 영향을 미치는 요인에 관한 연구

김원진,왕군철,김두리,최인영,허진아,최유정,장문영 대한감각통합치료학회 2011 대한감각통합치료학회지 Vol.9 No.1

목적 : 학령전기 아동의 글씨 쓰기 명료도 및 속도와 지각-운동 기술의 상관관계를 확인하고, 글씨 쓰기에 가장 영 향을 주는 요인을 알아보고자 하였다. 연구방법 : 덴버 발달 선별 검사를 통하여 정상 발달로 선별된 23명의 학령 전기 아동(평균 연령=68.61개월, SD=2.04)을 대상으로 글씨 쓰기 명료도 및 속도 측정을 위하여 한글 자모 쓰기 검사지를 사용하여 자음과 모음을 쓰도록 하였다. 시지각과 시각-운동 통합 수행 능력 측정을 위하여 시지각 발달 검사를 사용하였고, 소운동 협응 수행 능력 측정을 위하여 Grooved pegboard test를 사용하였다. 결과 : 글씨 쓰기 명료도와 전반적인 시지각, 비운동성 시지각, 시각-운동 통합, 우세손 소동작 협응의 상관관계는 없었으며, 글씨 쓰기의 속도는 전반적 시지각과 우세손 소동작 협응 항목에서 유의한 상관관계를 보였다. 회귀 분 석 결과 글씨 쓰기 속도에 가장 큰 영향을 주는 요인은 전반적 시지각 항목이었다. 결론 : 만 5~6세 학령 전기 아동의 전반적 시지각 능력의 발달을 향상시키기 위한 중재를 제공하는 것이 글씨 쓰기 의 속도 능력을 향상 시킬 수 있다는 것을 알 수 있다. Objective : This study investigated the relationships of handwriting legibility and perceptual-motor skills, and handwriting speed and perceptual-motor skills. And identified the predictors that most affect the handwriting of preschool children. Methods : Twenty-three typically developing preschool aged children (mean age: 68.61 months, SD=2.04) were selected through the Korean-Denver Developmental Screening Test-2(K-DDST-2). The children were tested with regard to handwriting legibility, visual perception, visual-motor integration and fine-motor coordination. Results : First, a significant relationship was not found among handwriting legibility, visual perception, visualmotor integration and fine-motor coordination. Second, a significant relationship was found among handwriting speed, visual perception and fine-motor coordination. Third, stepwise multiple regression analyses showed that general visual perception were significant predictors for handwriting speed. Conclusion : Occupational therapists should evaluate children's visual perception levels utilizing a standardized test, and focus on general visual perception in order to improve handwriting skill(speed). Also, occupational therapists are expected to play an important role in the management and treatment of children's handwriting skills.

상수도관의 노후도에 대한 환경영향인자의 상관성 분석

정원식,이현동,김이태,유명진 대한상하수도학회 2003 상하수도학회지 Vol.17 No.2

This study is performed to evaluate the correlation of environmental factors for drinking water pipe deterioration using statistical analysis such as multiple regression, cluster analysis, discriminant analysis, and the adequacy and dependability of grouping factors used to deterioration prediction model. Results of this study are presented that high correlation related to pipe deterioration is showed not laying year of pipe but characteristic of surrounding area and analysis of chemical components. Therefore, major influence factors of pipe deterioration for types of cast iron pipe are product quality of pipe, environmental factors using pipe deterioration evaluation model is classified to 4 types such as group related to pipe body and to hydraulic & water quality, and to characteristics of surrounding area, and to trouble & discontent of customer. And the very high adequacy of group classification is represented that the applied grouping items in this study are agree to previous studies.

CWM 연료의 연소 및 환경 특성 연구

정진도,이재원,유병구 忠南大學校 産業技術硏究所 1995 산업기술연구논문집 Vol.10 No.2

Basic combustion mechanism of CWM(Coal Water Mixture) together with the chemical properties of the coal used in the experiment were studied. Temperature distribution, combustion efficiency and exhaust gas characteristics were investigated, by using the boiler as capacity of 3.5ton/hr with variation of excess air and boiler loading. Further, it was found that conbustion regions of volatile matter and fixed carbon were divided clearly. And furnace temperature varied with boiler loading and excess air. When the boiler load was 40-60%, the maximum combustion efficiency up to 95-98% was obtained for all the coals fired in this study. The pollutant emission characteristics of exhaust gas was also favorable.