흰쥐에서 갑상샘 절제 후 재생에 따른 세포 및 세포사이물질의 변화

황영일,정용환,이왕재,황덕호,유영복,김혜숙,장가용 대한해부학회 1997 Anatomy & Cell Biology Vol.30 No.4

흰쥐 시상하부에서 NMDA에 의한 c-fos의 발현

이영기,최기열,이원돈,유영복,이왕재,황덕호,조사선,장가용 대한해부학회 1994 Anatomy & Cell Biology Vol.27 No.3

운동성 산화 스트레스와 항산화비타민의 보충이 말초단핵세포의 NF-kB 활성에 미치는 영향

진영수,박건구,박준영,김미정,이왕록,김혜영,이한준,박은경 대한스포츠의학회 2000 대한스포츠의학회지 Vol.18 No.2

Reactive oxygen species(ROS) are implicated in the pathogenesis of a wide variety of human diseases. Numerous studies indicate that ROS may serve as common intracellular molecules that contribute to the process of nuclear factor(NF)κB activation in response to a diverse stimuli. In our laboratory, we have demonstrated tat antioxidants could reverse the decline of immune function caused by exercise-induced ROS. Furthermore, it in necessary to understand a mechanism underlying ROS-dependent disorder in biological system. Recent studies have been shown that several gene expression were regulated by oxidants, antioxidants and other determinants of the intracellular reduction-oxidation(redox) state. In this process, NF-κB have been shown to play a important role. The purpose of the present investigation was to evaluate the effect of exercise-induced oxidative stress and antioxidnt supplementation on NF-κB activation in peripheral mononuclear cells. Forty male SD rats(4 weeks old) were randomly divided into noraml diet group and antioxidants(ATO) supplement group, and then ATO groups were treated with antioxidants(VE: 2001U/kg, VC: 50mg/rat, β-carotene: 300mg/kg, vitamin B6: 250㎍/100g, selenomethionine: 0.1mg/kg) for 16 weeks. After 16 weeks breeding at each condition, each group divided into two groups: Control group(CR) fed generally, Exercise group(CE) fed generally and followed by acute exercise 16 weeks later. Antioxidant Antioxidants and Exercise group(AE) fed with antioxidants and followed by acute exercise. The activation of NF-κB binding activity was increased after exhaustive exercise bout in both group. In addition, pretreatment of ATO group with the antioxidants mixture lead to the inhibition of NF-κB binding activity. This results suggest that NF-κB activation should be further studies in response to a variety of exercise.

소아 전풍 환자에 대한 임상적 고찰

강효준,왕한영,성호석 ( Hyo Jun Kang,Han Young Wang,Ho Suk Sung ) 대한피부과학회 1997 大韓皮膚科學會誌 Vol.35 No.3

Background: Pityriasis versicolor(PV) is a superficial mycosis, theoretically unusual in children. Epidemiologic and clinical data for children with PV under 14 years were collected. Objective . The purpose of this study was to evaluate the clinical features of PV in the young. Method: We included all cases of PV in patients under 14 years of age observed in our department from 1981 to 1995. All cases were diagnosed on the basis of clinical criteria and were confirmed by microscopic examination. Results : From 1981 to 1995 we encountered 32 cases of PV in children, compared with 637 cases in adults; thus children represented 4.7% of all cases. The ratio of male to female was l. 7:1. Among the age groups, the incidence was the highest in the 10-14 years(43%). The monthly prevalence was the highest in August. Distribution of the lesions were the face(40.9%), neck (25%), chest(13.6%), back(11.3%), extremities(6.8%) and abdomen(2.2%). The incidence of hypopigmented lesions was 70.4% and that of hyperpigmented lesions was 29.6%. Conclusion : This study confirms that the face is a predilectionl site for PV in children and all facial lesions are hypopigmented. Other clinical features are variable and similar to those of adults. (Kor J .Dermatol 1997;35(3): 431-434)

산화알루미늄-탄화티타늄(Al₂O₃-TiC) 세라믹 복합체의 방전가공

왕덕현,우정윤,윤존도,고철호,안영철,정영습 경남대학교 신소재연구소 1996 論文集 Vol.7 No.-

도전성 탄화티타늄 33무게%를 포함하는 산화알루미늄基 세라믹 복합체에 대한 방전가공을 시도하고 최적조건과 방전메카니즘을 조사하였다. 방전조건으로 전류 7-15A, 듀티팩터 0.24-0.45, 인가전압 40V를 사용하여 방전가공을 실시하였는데, 전류가 7A이하, 듀티팩터가 0.30이하일 때 가공이 잘 되었으며, 그 이상에서는 표면 파괴가 일어났다. 방전전류와 듀티팩터가 증가하면 공작물 제거속도는 증가하나 표면 거칠기도 역시 증가하는 것으로 나타났다. 방전가공 표면에 대한 미세구조 분석을 통하여 방전가공 메카니즘은 용융증발기구로 분석이 되었다. Alumina ceramic matrix composite containing electro-conductive titanium carbide of 33 weight % was machined by electrical discharge machining (EDM) method. The machining condition was 7-15A of current, 0.24-0.45 of duty factor, and 40V of applied voltage. When the current and duty factor were 7A and 0.30 or lower, respectively. the specimen were machined successfully. When the current and duty factor were higher. the specimen showed surface damage and fracture after machining. As the current and duty factor increased. the material removal rate(MRR) and maximum surface roughness increased. implying that the machining condition would be selected according to the requirement whether high speed machining or good surface finish is needed. By the microstructure analysis on the machined surface, the mechanism of machining was determined to be melting and evaporation.

용존 공기에 의한 여과지의 역세척 공정 개발

왕창근,오영미 忠南大學校 環境問題硏究所 2001 環境硏究 Vol.19 No.-

Rapid sand filters used for removing turbidity materials in drinking water treat ment plants should be periodically backwahed to eliminate filtered flocs. Water and water/air backwashing systems have been adopted traditionally. However, these systems have some drawbacks such as incomplete washing of filters, large amount of backwashing(DABW) process was developed(Patent pending) to solve the drawbacks mentioned above. Wahshing efficiency of rapid sand filter has been tremendously improved and head losses after backwashing decreased. Further, backwashing time could be reduced significantly resulting in saving large amount of backwashing water.

운동장을 이용한 우수의 포집, 수량 및 수질에 관한 연구

왕창근,이영복,이동곤 忠南大學校 環境問題硏究所 2003 環境硏究 Vol.21 No.-

In this study, quantity and quality of rainwater collected by soil and sand as the playground collection materials were investigated and CNURCPM (Chungnam National University Rainwater Collection Prediction Model) was developed to predict amount of collected rainwater. Quantity of collected rainwater in soil and sand (depth 5 cm) collection system was 615 L(63%) and 7,315 L(77%) for study period, respectively. Average turbidity of collected rainwater in soil and sand collection system was 9.70 NTU, 2.05 NTU for study period, respectively. In case of heavy metal, the concentrations of Fe and A1 were higher than the other heavy metals in both soil and the sand. But in this analyzing the Fe and A1 were less than the standard of water quality that was required in drinking water. So the collected water was insignificant because concentration of heavy metal was not serious. List of water quality; pH, TOC, COD_(Mn), NH_(4)-N, NO_(3)-N were lower or a little higher than the standard of water quality and the item of coli-form was higher than the standard of water quality. These result suggest that the water needs the second treatment such as disinfection. To predict amount of collected rainwater, CNURCPM was developed. For sand collection material, predicted amount by CNURCPM and actual collected amount were 7,534 L and 7,315 L, which were very closed.

정신질환자 가족의 부담에 관한 연구

왕영애,이충순,윤배중 용인정신의학연구소 1998 용인정신의학보 Vol.5 No.1

음률을 사용하는 무의미음절 청킹과 EMR아동의 단기기억 활성화

왕경수,김영생,김광재 全北大學校 敎育大學院 2003 敎育論叢 Vol.23 No.-

The purpose of this study was to investigate the effect of senseless syllable chunking used tune on activation of EMR children;s short term memory and their literacy. The research questions were as follows: 1. Is there any difference between ellaboration question and ellaboration explanation about the figures of 5 key consonents to upper/lower EMR children in acquisition of vowel 'ㅏ' syllables? 2. Are the tunes of song effective on chunking vowel 'ㅏ' syllables. 3. To upper/lower EMR children is the senseless syllables chunked effective on chunking other syllables without or with a final consonent like 'ㅇ, ㅁ, ㄴ, ㄹ, or ㅅ' or in each syllable ? Selected were five children who could not read Hangul at all from three grades of an elementary school located in the country of Jollabukdo. The major findings of this study were as follows: 1. There was a significant difference between elllaboration question and ellaberation explanation only for lower EMR children in acquisition of vowel 'ㅏ' syllables. 2. The tunes of song were effective on chunking 19 key syllables including 19 consonents and the vowel 'ㅏ' syllables. 3. To upper/lower EMR children the tunes of songs were effective on chunking 19 key syllables and 7 kinds of 95 syllable tables. In sum, especially only in the case of EMR children, decording letters is critically related to activation of short term memory and so STM-adapted teaching is critically important for them.

Bandom Amplified Polymorphic DNAs 기법을 이용한 Bifidobacteria의 신속한 동정

왕지원,민해기,장영효,강국희 성균관대학교 생명과학자원연구소 1995 生命資源科學硏究 Vol.2 No.1

Random Amplified Polymorphic DNAs (RAPD) has been applied to the identification of human intestinal anaerobic Bifidobacteria. Recently, The RAPD technique has been used to analyse DNA polymorphism of genomic DNA from eukaryotes such as plants and animals(1, 3, 4, 10, 11). But there were only several reports on the polymorphism of prokaryotic genomic DNA by using this method(2,7). Total 100 random sequence primers were used in screening of species-specific primer. The oligonucleotide primers were ten bases long and designed to have average G+C contents of 60 mol %. Eight species of Bifidobacteria from human feces were selected. According to conventional method genornic DNA were extracted from each bifidobacterium and then RAPD-PCR was performed. Four primers have produced distinct electrophoretic band patterns, RAPD markers. Especially arbitrary primer # 101 showed species-specific DNA polymorphism for each of Bifidobacterial genomic DNA tested. The arbitrary primer # 101 showed good reproducibility when the PCR conditions were optimized. And also primer # 156, # 174, # 183, have produced amplified PCR products but not for all of the strains tested. Better DNA polymorphism was observed when two arbitrary primers were used in combination.