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      • Morphine의 血漿 Corticosterone 增加作用에 미치는 副交感神經系藥物의 影響

        文永煥,全普權,申萬鍊 고려대학교 의과대학 1987 고려대 의대 잡지 Vol.24 No.1

        Buckingham suggested that the effects of opioid substances on CRF secretion are probably due partially to direct actions on the hypothatamus and partially to alterations in the activity of cholinergic and noradrenergic neurons in the central nervous system. In this paper, the influences of cholinergic and anticholinergic drugs on the morphine-induced increase of plasma corticotserone level was studied in male mice. The results obtained were summarized as follows; 1. The dose-dependent increasing effect of morphine on plasma corticosterone was significantly inhibited by naloxone. 2. Pilocarpine (0.1-2.0㎎/㎏), physostigmine(10-200㎍/㎏), carbachol(10-200㎍/), and nicotine(0.1-2.0㎎/㎏) induced the dose-dependent increase of plasma corticosterone level. Particularly, the increasing effect of physostigmine and carbachol was marked. 3. The increasing effect of morphine on plasma corticosterone was markedly enhanced by pilocarpine, physostigmine or carbachol and was slightly enhanced by nicotine. The combined effect of morphine with pilocarpine or nicotine showed a tendency to be strengthened by atropine. But the combined effect of morphine and physostigmine was little changed by atropine and the combined effect of morphine and carbachol was inclined to be decreased by atropine. 4. Atropine(1.0㎎/㎏)and hexamethonium(10㎎/㎏)induced the marked increase of plasma corticosterone level. But by the combined treatment of them, the plasma corticosterone level showed the initial marked increase followed by the abrupt decrease downward to the control level. The increase induced by the combined treatment of atropine or hexamethonium with morphine was rather lower than that induced by a single treatment of atropine or hexamethonium. These results suggest that the increasing effect of morphine on plasma corticosterone level is mediated rather by its direct action on hypothalamus and its indirect action on central noncholiergic neurones than by its action on central cholinergic neuronal function.

      • 통계적 기법을 이용한 BUS需要推定에 관한 연구 : 浦項市 住居開發地域을 中心으로

        임채문,박문하,박영환 대구대학교 과학기술연구소 1997 科學技術硏究 Vol.4 No.3

        This research is based on the transits of bus movement in the residence area around the center of Pohang city to estimate the future bus traffic volumes individual transits of each area that is those of living area, non living area, the number of students, and workers are investigated, 22 out of 25 zones, which intend to be more residential are selectedby the motheds of cluster analysis, stepwise regression and multi regression, in order to find out the relation between the bus traffic volume and the individual transit the analysis of the relation, which put the value of the zone transit on the formula as a variable, can formulate its influence on the bus traffic volume. if this analysis is applied to the future residential development area if will contribute to calculation of the number of bus users and the decision of allocation interval of buses and the number of bus lines

      • 안정화제 처리된 회수수를 사용한 콘크리트의 특성에 관한 실험적 연구

        박영신,박재명,이세현,이문환 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)

        Recently, Most enterprises produced ready mixed concrete uses a mixing water as a recycling water without a density control in proportion to guide and standard. That is a cause of deterioration in the concrete quality like a reduce of strength, laitance, crack, etc. This study shows basic materials for development of ready mixed concrete recycling water density control system that holds down a deterioration in the concrete quality by using a mixed water treated recycling water with stabilizing agent and examines a possibility of re-using components of cement in recycling water. Therefore, in the experiment, we make a recycling water contains 3,5,7% of solid content ratio examines a property of a mixing water with a stabilizing agent and without it. Results of this study is next as follow. 1. The slump is decreased 1~2cm in a mixing without a stabilizing agent and the mixing with a stabilizing agent is similar to the standard mixing. 2. The air content is 4~4.7% in proportion to an increase of solid content without a stabilizing agent and the mixing with a stabilizing agent is similar to the standard mixing. 3. The compressive strength of an early curing age is tendency to increase both the mixing without a stabilizing agent and the mixing with a stabilizing agent. But, After 14days is passed, Compressive strength is decreased in a mixing without a stabilizing agent but increased a mixing with a stabilizing agent.

      • Job shop에서 지체작업수 성과를 고려한 작업배정 규칙

        손영진,우종선,문석환 한국의사결정학회 2001 경영과학연구 Vol.10 No.-

        Scheduling techniques and dispatching rules are widely studied because of their simulation-based analysis of dispatching rules for scheduling in dynamic job shops taking into account of utilization on the shop floor and due-date tightness. This research proposed new dispatching rules for a job shop that are expected to minimizes the proportion of tardy jobs. With respect to the proportion of tardy jobs objectives, the relative performance of the proposed dispatching rules were evaluated against that of the well-known ones.

      • 공과대학 컴퓨터 교육 향상 연구

        박영필,민병렬,문영현,김상식,조원철,홍준표,이홍림,김재희,오두환 연세대학교 산업기술연구소 1988 논문집 Vol.20 No.2

        In accordance with the rapid advance of computer technologies, industries as well as the academic world become to apply the computer to various fields in engineering. Therefore, more realistic and effective computer educations should be provided in engineering colleges. This study proposes some schemes to elevate currently offered computer- related educations in engineering colleges. For this study, 10 major domestic and foreign engineering colleges were surveyed in the aspects of computer- related courses and computer systems offered by the colleges.

      • 大邱市 生活道路의 整備方向에 關한 硏究

        임채문,박영환,정만표 대구대학교 과학기술연구소 1995 科學技術硏究 Vol.2 No.2

        Today, it has been taking a serious view to make comfortable circumstances that are free from pollution, traffic problems, energy shortage, etc. Therefore, when we plan to improve the road condition in city, we should give priority to building familiar community road. Taking account of this, in the study I have studied the case and policies of foreign countries to community road. The results of this study can summarized as follows. 1 It should be accepted to equip large humps or round shaped humps (length:3.7m, height:l0.cm) that ate generally used in Austria. There is no doubt that traffic signs should be equipped before these humps. 2 Each zone of daily life should be setted up by range of about 1km2 and it should be given various traffic regulations or safety facilities for pedestrians, bicycles (especially, children or the old.l) 3 As living environment is getting worse by inflowing of passing cars, it is important to protect pedestrians, bicycles from cars. Generally, the policy to prohibit large cass(like trucks)into living aces has been taken. In addition to this, from now all the cars(like trucks) into living area has should be excluded from the area, except special cases. 4 The policy that pedestrians should be prior to cars must be enforced in Taegu city, and community road for both pedestrians and cars should be designed. 5 When plan to organize the network of pedestrian lane or bicycle road, we should collect public opinion and policies of executive organizations. Especially, in the case of giving great influence on community transportation as redevelopment of around railroad station, the schemes should be included how to connect pedestrian with car or public transit. Doing all this, the planner should consider the synthetic transportation planning for the small district in urban area.

      • 방사선 조사에 의한 phospholipase D 활성화 연구

        김영래,김기환,조문준,임규,황병두,박승길 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1

        Activation of oleate-dependent phospholipase D (PLD) isozyme by irradiation was reported previously. However, the effects of irradiation on other PLD isotypes (PLD1 and PLD2) have not been studied. There are several kinds of PLD isozymes in a cell. Therefore, it is difficult to study PLD isotype-specific activation in a cell by irradiation. We tested which isotype of PLD responds to irradiation. We used the fibroblasts cell lines overexpressing PLDl or PLD2 by introducing recombinant PLD1 or PLD2 cDNA. Phospholipids in cells were labelled with [(3)^H] myristic acid. Before irradiation, l-butanol was added. After irradiation with doses of 1, 2, and 10 Gray, we measured the formed phosphatidylbutanol containing [(3)^H] myristic acid. The overexpressed PLD isotypes were functional in those cell lines. PLD2 activity was enhanced by irradiation when we compared the PLD activations between control and PLD1 or PLD2 overexpressing cells. However PLD1 was not activated by irradiation. PLD2 isozyme, but not PLD1, was activated by irradiation. One Gray irradiation showed the maximal effect on PLD2 activation. The activation mechanism and physiological significance of PLD2 activation by irradiation remain to be uncovered.

      • 7個 結晶系의 唯一 X-線 回折强度 資料

        徐日煥,金光柱,秋錦洪,李珍昊,林星秀,柳保盈,金文執 충남대학교 자연과학연구소 1992 忠南科學硏究誌 Vol.19 No.1

        한 結晶의 構造는 唯一單位의 X-線 回折强度資料로부터 決定될 수 있다. Miller指數(hkl)의 函數인 回折强度Ⅰ(hkl)는 異常 散亂(anomalous scattering)이 無視될때 對稱中心點群 卽 Laue群의 對稱性을 나타낸다. 이 論文에서는 모든 結晶系에 對한 回折强度의 唯一單位를 Laue群들의 對稱性으로부터 誘導하여 놓았다. Crystal structures can be determined from the unique data of X-ray intensity. As the X-ray intensity Ⅰ(hkl), which is a function of diffraction plane (hkl), has a center of symmetry assuming anomalous scattering is negligible Ⅰ(hkl) shows the symmetry of a centrosymmetric point group, i.e., a Laue group. In this paper the unique data of the intensity for all crystal systems have been derived from the symmetries of Laue groups.

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