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      • 동거형태에 따른 젊은 남자성인의 식행동과 건강관련 행동의 차이

        박영숙,장지혜,임은희,한재라 순천향대학교 기초과학연구소 2001 순천향자연과학연구 논문집 Vol.7 No.2

        A survey was performed to 250 male young men who were living alone and shared living with friends in Chungnam province. Their average age was 22.6 years old, height was 171.8 cm, weight was 65.6 kg and BMI was 22.2 Comparing the prevalence of drinking, smoking and exercise, there were significantly different between living alone subjects and shared-living ones. The main value toward eating/meals was for hungry soultion. And we found many significant differences by living with or without companion. When young men living without companions, they shouved to be more in regular mealtimes, no-skipped meals, breakfast eating, adequate food amounts, eating-outs, etc. and to be less in pleasant mealtimes, various foods, snacking and especially late snacks. The good food intake pattern were highly scored in the alone-living group than the shared-living group, whereas the bad food intake pattern were also highly scoued in the alone-living group than the other. The latter might be due to the more food exposures because of companions. These findings could conclude that dietary behaviors of the young living alone were evaluated as good enough.

      • SCISCIESCOPUS

        One step bulk modification of poly(L-lactic acid) composites with functional additives to improve mechanical and biological properties for cardiovascular implant applications

        Kang, Eun Young,Choi, Bogyu,Park, Wooram,Kim, Ik Hwan,Han, Dong Keun Elsevier 2019 Colloids and Surfaces B Vol.179 No.-

        <P><B>Abstract</B></P> <P>Poly(L-lactic acid) (PLLA) has been widely used as a promising biomaterial in biomedical applications due to its biodegradability and high mechanical strength. However, because of the inherent brittleness, low impact resistance, and weak thermal stability of PLLA, the modification process is usually required to utilize it for biomedical devices. Furthermore, acidic byproducts resulting from the hydrolysis of PLLA after implantation reduce the pH of the surrounding environment and cause inflammatory responses in the implanted area, leading to the failure of their clinical applications. To this end, here, we demonstrate a novel modification process for the PLLA composite with various functional additives, such as cis-aconitic anhydride (AA), triacetin (TA), isosorbide derivative (ISB), and/or Pluronic® F127 (F). The modified PLLA composite with TA and F (PLLA/TF) showed significantly improved elongation at break and Young’s modulus and retained tensile strength. Moreover, incorporating magnesium hydroxide (MH) nanoparticles (PLLA/TFMH) significantly reduced acid-induced inflammation responses caused by the acidic degradation products of PLLA. Reduced plasma protein adsorption was observed in the PLLA/TFMH. These results suggest that the one step bulk modification of biodegradable PLLA using TA, F, and MH will have great potential in cardiovascular implant applications.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Improved mechanical properties of PLLA via one step bulk modification with TA and F. </LI> <LI> Reduced acid-induced inflammation via one step bulk modification of PLLA/TF with MH. </LI> <LI> Increased homogeneity of MH distribution in one step bulk modified PLLA/TFMH. </LI> <LI> Enhanced hemocompatibility of PLLA/TFMH. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

      • Multiple myeloma 환자에서 Bortezomib치료 후 발생한 마비성 장폐색증 1례

        김준영,이원식,손창학,박성길,진한영,박석주,조영완,정은욱,강명주,박정하,주영돈 인제대학교 2006 仁濟醫學 Vol.27 No.-

        Bortezomib is the first clinically available proteasome inhibitor that is clinically effective in the treatment of multiple myeloma. A proteasome inhibitor acts through multiple mechanisms to arrest tumor growth, tumor spread, and angiogenesis. The main adverse effects of bortezomib are gastrointestinal symptoms, cytopenia, fatigue, and peripheral neuropathy. To date, severe paralytic ileus has not been reported as a toxic effect of bortezomib treatment in multiple myeloma. Bortezomib is a novel agent that has only been used clinically for 30 months, so a need exists to further evaluate its toxicity. We report a case of grade Ⅲ (NCI CTCAE v3.0) or grade Ⅳ(SWOG toxicity criteria) paralytic ileus in a 65-year-old man with relapsed multiple myeloma who underwent one cycle of single-agent bortezomib treatment scheduled in a 21-day cycle (1.3 mg/㎥ as a single i.v. bolus on days 1, 4, 8, and 11).

      • KCI등재

        Factors associated with the risk of colorectal neoplasia in young adults under age 40

        Ilsoo Kim,Han Hee Lee,Young Jae Ko,Ho Eun Chang,Dae Young Cheung,Bo-In Lee,Young-Seok Cho,Jin Il Kim,Myung-Gyu Choi 대한내과학회 2022 The Korean Journal of Internal Medicine Vol.37 No.5

        Background/Aims: Recent epidemiologic studies have shown a continued increase in colorectal cancer incidence among younger adults. Little is known about the factors that contribute to the development of young-onset colorectal neoplasia (CRN). Methods: A cross-sectional analysis was performed for individuals younger than 40 years who underwent colonoscopy in Seoul St. Mary’s Hospital and its affiliated health screening center. High-risk CRN was defined as adenoma or sessile serrated lesion ≥ 10 mm, with three or more adenomas, villous histology, high grade dysplasia, or carcinoma. Results: Of these 13,621 included participants, 2,023 (14.9%) had one and more CRN. Young patients with CRN tended to be elderly, male, obese, smoker, having a habit of drinking, and having comorbidities such as hypertension, dyslipidemia, diabetes, and chronic kidney disease. In a multivariate analysis adjusted for age, sex, obesity, smoking status, and alcohol intake, old age (odds ratio [OR], 1.086; 95% confidence interval [CI], 1.054 to 1.119), male sex (OR, 1.748; 95% CI, 1.247 to 2.451), obesity (OR, 1.439; 95% CI, 1.133 to 1.828), and smoking (OR, 1.654; 95% CI, 1.287 to 2.127) were independent risk factors for overall CRN. Obesity and smoking as two modifiable factors increased the risk for high-risk CRN even more than for overall CRN (OR, 1.734; 95% CI, 1.168 to 2.575 and OR, 1.797; 95% CI, 1.172 to 2.753, respectively). Conclusions: Obesity and smoking were modifiable risk factors for CRN in young adults. They increased the risk for highrisk CRN even more than for overall CRN. A colonoscopy might be beneficial for young individuals with these factors.

      • KCI등재

        반말체 어미 ‘-게’의 의미기능 연구

        이한민 ( Lee Han-min ),조은영 ( Cho Eun-young ) 국어학회 2015 국어학 Vol.74 No.-

        본고는 조은영·이한민(2011)에서 정리하였던 연결어미에서 종결어미화된 ‘-게’의 의미기능과 문법화 과정의 연장선상에서 추가적인 ‘-게’의 용법으로 [가정]과 [추측유도]의 의미기능을 살피고자 하였다. [가정] ‘-게’구문은 조건절인 선행절과 결과절인 후행‘-게’절로 구성되며, 선행절의 부정을 이끄는 반어적 진술의 수사의문문으로 사용된다. [가정] ‘-게’는 선어말어미 ‘-었-’이 결합할 수 있는 점, 후행 ‘-게’절이 단독으로 쓰일 수 없는 점, 의미적으로 후행절의 내용이 선행절을 강조하는 기능을 한다는 점에서 [완료결과] ‘-게’와 연관성을 보인다. [추측유도] ‘-게’구문은 화자가 알고 있는 어떠한 사실에 대하여 청자의 ‘추측을 유도’하는 발화에서 사용되며, 설명의문문 형식이나 선택의문문 형식으로 쓰이지만, 청자로부터 신정보를 얻기 위한 질문으로는 사용되지 않는다. [추측유도] ‘-게’절은 선어말어미 ‘-었-’이 결합할 수 있는 점, 이미 이루어진 상황 혹은 확정된 사실에 대한 것이라는 점에서 [완료결과] ‘-게’와 유사한 의미를 보인다. 그러나 단독으로 사용될 수 있는 구문인지, 발화의 초점이 ‘-게’절에 있는지의 여부에서 차이를 보인다. [가정]은 [완료결과]와 통사적, 의미적으로 비슷한 부분이 많고, [완료결과]와 동일한 형식의 문장이 [가정]의 쓰임을 보이는 과도기적 형태도 존재한다. 따라서 [가정]은 [완료결과] 이후에 연결될 수 있는 단계로 볼 수 있다.[추측유도]의 경우에는 [완료결과], [가정]과 통사적, 의미적으로 공통적인 부분이 있지만, 조은영·이한민(2011)에서 정리한 종결어미 ‘-게’의 단계별 의미기능과 함께 다룰 수 있을지에 대해서는 결론을 내리지 못하였다. [추측유도]가 연결어미 ‘-게’에서 문법화한 종결어미가 아니라 다른 기원을 갖는 ‘-게’의 의미기능일 수도 있다는 가능성도 열어 두어야 할 것이다. 다만, [추측유도] ‘-게’가 공시적인 쓰임에서 연결어미 ‘-게’에서 문법화한 종결어미의 의미기능들과 연관성을 가지는 것은 분명하다. This paper tries to figure out the additory usage of final ending ‘-ge’―the semantic function of [supposition] and [assumption inducement]― as an extension to the grammaticalization process of final ending ‘-ge,’ originated from a connective ending ‘-ge’ organized by Cho, Eun-Young & Lee, Han-Min (2011). The sentence structure of [supposition] ‘-ge’ is consisted of the antecedent clause, which is a conditional clause, and the following clause ‘-ge’ clause, and is used as a rhetorical interrogative of an ironic statement denying the antecedent clause. It also shows some correlation with [completion result] ‘-ge’, considering the fact that ‘-ge’ can be combined with the tense prefinal ending ‘-eoss-’, and that following ‘-ge’ clause cannot be used by itself, and that the following clause can emphasize the antecedent clause semantically. The sentence structure of [assumption inducement] ‘-ge’ is often used when inducing a listener to make an assumption of a matter that a speaker already knows. However, it is not used as a question to get a new information from the listener although it may be used in a form of a wh-question or an alternative question. [Assumption inducement] ‘-ge’ clause shows some similar meaning with that of a [completion result] ‘-ge’ clause regarding the fact that it can be combined with the tense prefinal ending ‘-eoss-’ and that this clause is about something that has already happened or determined. However, it shows some differences in that whether this sentence structure can be used alone or its focus point of utterance is on ‘-ge’ clause itself. There exists several similarities between [supposition] and [completion result] in syntactic and semantic context, in addition to a transitional phase in which a sentence is used as a [supposition] clause when sentence structures exhibit identical features to [completion result]. Thus, it can be seen that [supposition] is a connecting stage following the [completion stage]. In case of [assumption inducement], there exists several similarities between [assumption inducement], [completion result] and [supposition] in syntactic and semantic context. However, the authors were not able to draw a definitive conclusion as to whether [assumption inducement] can be dealt with changing meanings of semantic functions of final ending ‘-ge,’ organized in Cho, Eun-Young & Lee, Han-Min (2011). Thus, there is an implied possibility that [Assumption inducement] may not be a grammaticalized final ending ‘-ge’ but that of different origins with dissimilar semantic functions. In the synchronic use, however, it is certain that [assumption result] ‘-ge’ has a definitive correlation with semantic functions of final endings that are grammaticalized in the connective ending ‘-ge.’

      • KCI등재후보

        강원도 화천군 수달(Lutra lutra) 서식지의 식생 구조

        서형수 ( Hyung Soo Seo ),신영섭 ( Young Seob Shin ),이경은 ( Kyung Eun Lee ),김윤미 ( Yoon Mi Kim ),전미나 ( Mina Jeon ),남택우 ( Taek Woo Nam ),한성용 ( Sung Yong Han ),정연숙 ( Yeonsook Choung ) 한국하천호수학회 2014 생태와 환경 Vol.47 No.special

        In order to determine whether vegetation would be one of the factors for the selection of otter home range, vegetation structure and other potential factors were studied in Hwacheon, Korea. Thirteen sites, otter’s activity found and not found, were investigated in North Han River and connected tributary streams of Hwacheon-gun. Three types of vegetation were classified by cluster analysis, which is short grass, tall grass and shrub type. Vegetation zone of each channel is composed of either one type, or mosaic of tall grass and shrub type. Short grass type is common in Lake Paro and upper North Han-river where water level is highly variable throughout a year. Therefore, annual species such as Persicaria nodosa, Fimbristylis dichotomam and Chenopodium ficifolium are the most dominant. Shrub type is common at the downstream sites of Jichon stream and along mainstream of North Han River down Lake Paro. A shrub species, Salix koreensis, is the most common. Tall grass type is dominant occupying the most vegetation zone of the tributary channels. Phragmites japonica is absolutely dominant. Due to its dense cover, a few plant species are co-existed. Otter activity was found in all three vegetation types and no marked activity was found at some sites of tall grass type. There is no difference in species composition and physiognomy between tall grass sites with and without otter activity, while it shows significant difference in fish availability between two groups. Overall we found that home range of otters in the region is along the mainstream and downstream of tributary streams with high fish availability in all vegetation types and in various human activity levels.

      • 갑상선 유두암이 병발된 가족성 대장 용종증 1예

        백종현,소창배,이은영,이지숙,신은경,박은호,서정아,양재홍,송준영,박선자,박요한,최영식 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.2

        Familial adenomatous polyposis (FAP) is an autosomal dominant syndrome, typically characterized by multiple colorectal adenomas and increased incidence of colorectal carcinomas if it is not treated. Moreover, a variety of extracolonic manifestation are seen. The prevalence of thyroid tumors developing in patients with FAP is about 1∼2%. Generally, papillary thyroid cancer indicates low mortality but ,however, as people get older, the cancer becomes more aggressive. So, the operation is required. Recently we experienced a case of FAP, presenting with papillary thyroid carcinoma, and reported with a brief review of literatures.

      • SCOPUSKCI등재
      • KCI등재후보

        대량의 각혈로 사망한 장티푸스 1예

        한상우,유진홍,권순석,김성훈,박지찬,홍은정,최경성,박용완,장준희,안지원,박유경,강지영,박상미,신완식 대한감염학회 2004 감염과 화학요법 Vol.36 No.5

        We experienced a 25 year-old male patient with typhoid fever complicated with massive hemoptysis. Pulmonary complication in typhoid fever is very rare and to our knowledge, there has been no report of hemoptysis as a main cause of death with this disease. We herein report a rare case of typhoid fever.

      • SCOPUSSCIEKCI등재

        교정환자의 장치 순응도와 관련된 요인들의 조사연구

        한은주,유영규 대한치과교정학회 1993 대한치과교정학회지 Vol.23 No.4

        In orthodontic field, although lots of new materials have been developed and many mechanics introduced, we can face the case patient cooperation still remain a problem to solve. So, factors related to the compliance of 254 adolescent orthodontic patients using intraoral elastic or extraoral orthopedic appliances were under investigation. The study subjects were 11 to 18 years old and from 5 exclusive orthodontic clinics in Seoul. The subjects were asked to fill a questionnaire and compliances were evaluated by their assigned orthodontists. The questionnaire was consisted of 63 questions, and they represent 13 factors―7 psychological & 6 nonpsychological fators. The collected data were analyzed using ANOVA test between the compliance group and the factors. 1. The compliances were evenly distributed in both sex and age groups. 2. As a whole, it was found that the Attitude towards appliances ffactor affected the degree of compliance. 3. Besides that, in younger(11-12) age group, Pain and discomfort associated with treatment factor was also found to be related to the degree of compliance. 4. On the contrary, in older(16-18) age group, the degree of compliance was influenced by the factor of Achievement motivation, Role expectation, parental relationship.

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