疎風湯의 消炎·鎭痛作用에 관한 硏究

劉善美,林起龍,嚴基鎭,文永熙 조선대학교 약학연구소 1993 藥學硏究誌 Vol.15 No.1

This study was attempted to examine the effect of Sopung-Tang extract(STE) on anti-inflammatory action in rats, analqesic action and the acute, subacute toxicity in mice. In anti-inflammatory activity in rats, STE was shown to have significant preventive effect in the edema induced by Freund's conplete adjuvant and 5% acetic acid. In analgesic activity in mice, STE was shown to have significant analgesic action on the writhing syndrome in mice induced by 0.7% acetic acid. In acute toxicity test in mice, STE showed 10% mortality at 2000㎎/㎏ . and 1200㎎/㎏ i.p. In subacute toxicity test in mice, STE was not showed for 19 days. Serum uric acid in treated by adjuvant method rats were slightly decreaced by comparing with the control group. During the administration of extracts the body weight increased, but the liver and spleen weight was not changed.

일 고등학교 학생들의 건강증진행위와 관련요인

유상학,김진선 朝鮮大學校 附設 醫學硏究所 2002 The Medical Journal of Chosun University Vol.27 No.2

Background and Objectives: Little is known about the health promoting behaviors of adolescence. The purposes of this study were to identify healthUpromoting behaviors of high school students and to explore the predictors of their health-promoting behaviors. Method: A crossUsectional study was conducted. Data were collected from 751 students in a technical high school located in G city using a structured questionnaire. Results: High school students in this study practice health promoting behaviors relatively well. Among 6 dimensions, students reported the highest score on the interpersonal relationship dimension and the lowest score on the health responsibility dimension. Of 751 respondents, 26.2% was current smokers and 64.6% was current drinkers. Health-promoting behaviors were predicted by selfUeff'icacy, family support, school life adaptation, and gender. Students who reported higher self-efficacy, higher family support, and higher school life adaptation practice more health promoting behaviors than their counterparts. Moreover, boys reported higher health promoting behavior scores than girls, Conclusion: Health promotion programs to increase health responsibility of high school students are need to be developed. There were great needs to develops tobacco cessation and drink control programs. More studies are needed to identify predictors of high school students' health promoting behaviors.

급성충수돌기염으로 발현된 방선균증 2예

조진원,송진영,김창억,민영훈,최창순,우흥정,현인규,김종현,유기철,채승완,손진희 대한화학요법학회 2001 대한화학요법학회지 Vol.19 No.1

The Actinomyces species are normal flora of oral cavity and upper intestine characterized as gram-positive, non-spore-forming anaerobic or mjcroaerophilic rods. Actinomycosis is a chronic suppurative and granulomatous disease characterized by abscess, sinus, abundant granulation and mass. The appendix is the commonly involved site among abdominal actinomycosis. Abdominal actinomycosis is often difficult to diagnose before operation because of no reliable clinical features and infrequency of the disease. We report two cases of abdominal actinomycosis which were manifested as acute appendicitis. Those were detected Incidentally tv the pathologist after routine appendectomy. Both patients were successfully treated with appendectomy followed by proper antibiotics use.

호스피스 병동과 일반병동의 말기암환자의 간호중재 비교

노유자,한성숙,용진선,송민선,홍진의 가톨릭대학교 간호대학 호스피스 교육연구소 2002 호스피스논집 Vol.6 No.-

The purpose of the study was to compare symptoms, medical therapies, and nursing interventions with terminal cancer patients during the last four weeks of their lives in a hospice unit and general units. For the descriptive survey study, data were collected by reviewing the charts of 243 patients who died of terminal cancer at K hospital in Seoul. The data was analyzed using Chi-square test and t-test. The study findings are summarized as follows: There were higher frequencies in physical symptoms of constipation, itching sensation, pain, sleeping disturbance, sore, and urinary difficulty for those patients in the hospice unit than those patient in general units. All emotional symptoms were recorded significantly higher for those patients in the hospice unit than those in general units. Regarding the major medical treatments, pain control was used significantly more for those patients in the hospice unit but antibiotic therapy and resuscitation were used significantly more for those patients in general units. The hospice unit provided more comprehensive nursing interventions including psychological, spiritual, and family cares as well as physiological care for terminal cancer patients. The facts showed that those patients who need hospice care in general units should be referred to the hospice unite at an appropriate time.

8.3% Carbamide Peroxide 함유 펜 형 자가미백제인 BIancTis Forte의 색조개선 및 안전성에 관한 임상연구

이진경,민선홍,홍성태,오소람,정신혜,황영혜,유성엽,배광식,백승호,이우철,손원준,금기연 대한치과보존학회 2009 Restorative Dentistry & Endodontics Vol.34 No.2

This clinical study evaluated the whitening effect and safety of polymer based-pen type BlancTis Forte(NIBEC) containing 8.3% carbamide peroxide. Twenty volunteers used the BlancTis Forte whitening agent for 2 hours twice a day for 4 weeks As a control. Whitening Effect Pen (LG) containing 3% hydrogen peroxide was used by 20 volunteers using the same protocol. The change in shade (ΔE^(*) color difference) was measured using Shadepilot™ (DeguDent) before, during and after bleaching (2 weeks, 4 weeks and postbleaching 4 weeks). A clinical examination for any side effects (tooth hypersensitivity or soft tissue complications) was also performed at each check-up. The following results were obtained. 1 Both the experimental and control groups displayed a noticeable change in shade (ΔE) of over 2 No significant differences were found between the two group (p>0.05) implying that the two agents have a similar whitening effect. 2 The whitening effect was mainly due to changes in a and b values rather than in L value (brightness). The experimental group showed a significantly higher change in b value thus yellow shade than the control(p < 0.05) 3 None of the participants complained of tooth hypersensitivity or soft tissue complications confirming the safety of both whitening agents 8.3%의 carbamide peroxide를 함유한 펜형 코팅용 미백제인 BlancTis Forte (NIBEC, Seosul & JinCheon)를 실험군으로, 3% hydrogen peroxide를 함유한글 Whitening Effect Pen (LG. Seoul) 제재를 대조군으로 각각 피험자 20명에게 2시간씩 1일 2회 제조사의 지시대로 치아표면에 4주간 적용하도록 지시하고 색조개선 효능과 안전성을 평가하였다. 미백 효과는 미백 전 및 미백 2주, 4주 및 미백 종료 4주 후에 Shadopilot™을 이용하여 색 변화를 측정하였고, 매 내원시기마다 모든 환자는 치수생활력 검사와 치주 및 치태 검사를 통해 부작용 여부 (치아과민증 및 구감 내 연조직의 부작용)를 기록한 후 다음과 같은 결과를 얻었다. 1.실험군 및 대조군의 색 변화량 (ΔE)은 2이상으로 인지할 수 있는 색 변화를 보였으며, 두 제품 간에는 통계적으로 유의한 차이를 보이지 않아 (p > 0.05) 유사한 미백효능을 나타냄을 알 수 있었다. 2,미백효과는 명도의 개선보다는 주로 a. b값의 변화에 의한 것으로 특히 실험군에서 b값의 변화, 즉 황색조의 개선효과가 대조군에 비해 유의성 있게 높은 것으로 나타났다 (p <0.05). 3.치아나 치은의 과민증이나 이상증상을 호소하는 피험자는 없어 두 제품 모두 안전성을 확인할 수 있었다.

반복적인 급성 신부전을 유발한 호산구성 장염 1 예

정혜진;김현태;김유선;정현걸;강윤경;문정섭 인제대학교 2011 仁濟醫學 Vol.32 No.-

Eosinophilic gastroenteritis is a rare disorder of unknown etiology characterized by presence of gastrointestinal symptoms, eosinophilic infiltratio n of one or more parts of gastrointestinal tract without involvement of other organs and absence of parasitic infestation. The clinical presentation depends on the extents and depths of eosinophilic infiltration. Mucosal involvement may result in abdominal pain, nausea, vomiting, diarrhea and weight loss. We report a case of eosinophilic enterocolitis in a 55-year-old female presented with abdominal pain and watery diarrhea resulting in recurrent acute renal failure.

호스피스 병동과 일반병동의 말기암환자의 간호중재 비교

노유자,한성숙,용진선,송민선,홍진의 성인간호학회 2002 성인간호학회지 Vol.14 No.4

Purpose: The purpose of the study was to compare symptoms, medical therapies, and nursing interventions with terminal cancer patients during the last four weeks of their lives in a hospice unit and general units. Method: For the descriptive survey study, data were collected by reviewing the medical records of 243 patients who died of terminal cancer at K hospital in Seoul. The data was analyzed by using Chi-square test and t-test. Result: The study findings are summarized as follows. There were higher frequencies in physical symptoms of constipation, itching sensation, pain, sleeping disturbance, soreness and dysuria for those patients in the hospice unit than those patient in general units. All emotional symptoms were recorded significantly higher for those patients in the hospice unit than those in general units. Regarding the major medical interventions, pain management was used more significantly for those patients in the hospice unit, but antibiotic therapy and resuscitation were used more significantly for those patients in general units. Conclusion: The hospice unit provided more comprehensive nursing interventions including psychological, spiritual, and family cares as well as physiological care for terminal cancer patients. The facts showed that those patients who would need hospice care in general units should be referred to the hospice unit at an appropriate time.

특수학교 재량활동 교육과정의 편성과 운영

이유훈,김경진,김규선,김형일 국립특수교육원 2000 교육과정의 편성과 운영 Vol.- No.1

본 연구는 제7차 특수학교 교육과정에서 많은 비중을 차지하고 있는 재량활동이 각 특수학교에서 보다 효율적으로 운영될 수 있도록 지원하기 위해 시도되었다. 이를 위해 본 연구에서는 각 시ㆍ도 교육청의 재량활동에 관한 지침서를 분석하였고, 전국 특수학교를 대상으로 재량활동 교육과정 편성ㆍ운영 방안에 대한 현장 교사들의 의견을 수렴하였다. 이러한 자료를 통해 나타난 요구와 시사점을 토대로 특수학교 재량활동 편성ㆍ운영방안을 제시하였다. 본 연구에서 다른 연구내용별 주요 연구결과를 정리하면 다음과 같다. 시ㆍ도 교육청 재량활동 지침 각 시ㆍ도 교육청에서는 특수학교 교육과정 편성ㆍ운영지침을 작성하여 이를 관내의 지역교육청과 각 학교에 제시하고 있었다. 분석한 결과에 따르면, 편제 및 시간배당 기준은 국가수준과 동일한 배정을 하고 있었다. 그리고 대부분의 시ㆍ도 교육청에서는 재량활동 시간확보 및 운영, 평가의 질 관리, 치료교육, 평가내용과 방법에 대하여 그 강조점을 두고 있었다. 그러나 일부 영역을 제외하고는 시ㆍ도 교육청 지침의 내용이 국가수준에서 제시한 재량활동의 내용과 거의 동일하였다. 따라서 지역교육청 나름의 특성을 살린 재량활동 지침을 제시할 필요가 있다고 본다. 재량활동 교육과정 편성ㆍ운영을 위한 교사요구 분석 재량활동 교육과정 편성ㆍ운영에 대한 실태조사에서 특수학교 대부분이 재량활동을 계획하고 운영하는데 있어 애로를 느끼고 있었다. 그 이유로는 재량활동에 대한 프로그램의 부재와 재량활동에 대한 교사들의 인식부족, 계획 수립 및 운영 미숙, 시설ㆍ재정적 지원의 부족을 들고 있었다. 이러한 애로점을 해소하기 위해서는 무엇보다도 먼저 재량활동에 대한 다양한 편성ㆍ운영방안과 교육 프로그램이 개발ㆍ제공되어야 한다는 것이다. 특수학교들의 재량활동 운영주체로는 학교 교육과정 운영위원회를 들고 있고, 재량활동을 편성 할 때 '학생들의 능력과 특성', 학부모 및 교사들의 의견이 반영되어야 한다는 의견이 재배적이었다. 그리고 재량활동 시간배당에 있어서는 국가수준에서 제시한 시간만으로도 충분한 것으로 여기고 있으며, 기본교육과정은 교과 재량활동과 창의적 재량활동 구분 없이 융통성 있게 활용하기를 원하고 있다. 재량활동의 지도주체에 대해 정신지체ㆍ정서장애학교에서는 담임으로 응답한 반면, 시각ㆍ청각ㆍ지체부자유학교 교사는 따라 다양한 반응을 보이고 있었다. 그러나 장애역역에 관계없이 재량활동의 하위영역에 따라 다양한 지도주체를 모색할 필요가 있다고 본다. 이것은 학습진단 구성과도 연관될 수 있는데, 많은 교사들은 현재의 집단편성 방식에서 벗어나 재량활동의 모든 하위영역에서 활동중심의 집단편성을 원하고 있었고, 특히 창의적 재량활동에서는 좀더 다양한 집단으로 구성해야 한다는 반응을 보이고 있었다. 시간운영에 있어서는 매주 정해진 날에 실시해야 한다는 반응이 대부분이었지만, 시각ㆍ청각ㆍ지체부자유학교의 범교과 학습과 자기주도적 학습에서는 좀더 다양한 시간배정이 이루어지기를 원하고 있었다. 특히, 자기주도적 학습에서 각 특수학교들이 특정한 정해진 날에 체험학습의 날이나 책가방 없는 날과 같이 별도계획으로 운영해야 한다는 학교들도 있었다. 이러한 시간 운영과 관련한 지도방법에 있어서는 하위영역에 구분됨이 없이 모든 학교가 견학과 체험학습을 선호하고 있었다. 지도내용에 있어서는 기본적인 교과목에 대한 이해를 중심으로 이루어져야 한다는 시각ㆍ청각ㆍ지체부자유학교의 반응을 제외한다면, 사회생활 적응을 위한 기초생활 지도와 일상생활 적응, 그리고 현장학습과 같은 체험학습을 통한 내용을 대부분 선호하였다. 각 특수학교에서 제시한 재량활동 프로그램을 분석한 결과 일부학교를 제외하고는 그 유형들이 비슷하고 영역도 특별활동이나 사회교과 영역과 크게 구분이 되지 않은 것으로 나타났다. 재량활도에 대한 평가는 학생들의 다양한 활동과정을 평가할 수 있는 포트폴리오 방식을 선호하고 있었다. 기타 요구사항 재량활동의 활성화 방안에 있어서는 '교수ㆍ학습자료의 개발 및 보급이 우선되어야 한다'는 반응이 가장 많았으며, 그 다음으로 '학교장의 관심과 적극적인 자원', '학교의 잡무감소', '학급당 인원의 감소'등을 요구하였다. 시ㆍ도 교육청에 대한 요구사항으로는 역시 '프로그램의 개발 보급', '잡무 감소', '체험학습 활동에 대한 경비 자원', '교과전담 교사 확보' 및 '다영한 전무교사의 확보', '교사에 대한 재량활동 관련 연수기회 제공', '학교간 재량활동 운영에 관한 정보교환 및 공동 프로그램 운영지원'등을 들고 있었다. 재량활동 편성ㆍ운영방안에 있어서는 단위학교에서 재량활동을 편성할 때 기본적인 도움이 될 수 있도록 하기 위하여 하위영역별 사항과 이에 따른 운영방안을 제시하였다. 이를 위하여 첫째, 재량활동 편성ㆍ운영방안을 하위영역별로 나누어 하위영역별 편성방향, 시간배당, 지도내용, 집단구성, 지도방법, 평가내용을 제시하였다. 둘째, 각 하위영역별 시간배당, 지도내용, 집단구성, 지도방법, 평가방안에 대한 여러가지 가능한 방안을 제시하였다. 셋째, 일반학교와 특수학교에서 실제로 활용하고 있는 다양한 예시자료를 제시하였다. 넷째, 일반학교의 재량활동 운영과 관련된 우수 연구보고서와 특수학교에서 운영히고 있는 재량활동 사례를 정리하여 부록에 제시 하여 다양한 실천 자료를 참고할 수 있도록 하였다. This study aims at groping for effective application methods of optional activities for special schools. For this purpose, a close analysis was made on the guidelines for optional activities published by Metropolitan and Provincial Office of Education(MPOE), and extensive opinion on schemes for organizing and implementing the curriculum were collected from school teachers. The data gathered in this process present requirements and suggestions for optimal designs for organizing and implementing optional activities in special schools. The results of this study can be summarized as follows: Clarification of theoretical backgrounds of optional activities. Through clarifying various theoretical backgrounds, we identified its related meaning of character, organization, implementation process and assessment. Guidelines of the Metropolitan and provincial Office of Education(MPOE) Each MPOE has worked out and provied schools with its own guiding principles on the organization and implementation of special education curricula. The systems of organization and the standards of subject time alloment are almost the same as those of state level issued by the ministry of education. Most MPOE give directions that each school should secure and implement optional activities with an emphasis on enhancing the quality of assessment management, therapy education, as well as the contents and methods of assessment. Except some areas, most directions for optional activities from MPOE of education are not much different from those of the Ministry of Education. It is, therefore, necessary that each MPOE should provide its own directions as to optional activities. Analysis of teachers' needs about effective application method of optional activity. An investigation into actual condition activities reveals that most special schools have difficulty in planning and operating the activities, because of lack of diverse programs, shortage of knowledge about the activities, unskilled planning and implementation of the activities, insufficient facilities and financial support. The first thing to break these obstacles is to develop and provide diverse programs and devices for the organization and operation of the activities. The curriculum steering committee is regared as the primary implementation body for optional activities in special schools. Optional activities should reflect each student's ability and specially as well as the opinions of his/her parents and teachers. The time allotted by the Ministry of Education is regarded enough for individual school's optional activities. There are two kinds of optional activities: one by subject matters and the other by creative optional activities, but basic curriculum requires flexible application of both. As to the measurement of optional activities, schools for mentally retarded or handicapped students responded their home-room teachers should take the initiative, but school for the blind, the deaf, or the crippled said that different teachers in different fields should take the lead in their respective major subjects. Regardless of handicap degrees, it is necessaty to set various teaching intiatives according to sub-areas of optional activities, which is closely related to the organization of learning groups. Many teachers wanted to form groups geared to focus on more creative optional activities in sub-areas rather than their present groupings. Most teachers reponded that the time for the activities should be fixed on a specific weekday. Teachers also wanted that more various time should be allotted to the integrated study and self-directed study of the schools for the blind, the deaf, or the crippled. Some special schools had the opinion that self-directed study should be operated on a fixed day as the same way as the day for learning through experience or the day without schoolbag goes. As to the teaching methods, all the schools preferred the field study or learning through experience without regard to the division of sub-areas of optional activities. The contents of special school teaching were maintained to be focused on understanding the basic subjects, but most schools wanted optional activities to comprise learning the basic social life, getting acquainted with everyday life, and on-the-spot learning. An analysis on optional activities of special school showed that most activity types of the schools are nearly the same, and their areas of activities are not greatly different from those of club activities or social science subjects designed by the Ministry of Education. As for the assessment method for optional activities, the protfolio system is most preferred because it assesses each student's process of diverse activities. Other requirements In order to activate the optional activities, most schools preferred the development and distribution of teaching-learning materials. Next comes the school principal's concern and support for the activities, diminishing teachers' sundry duties, and reducing class-size. Teachers also required that each MPOE should take active measures to develop and distribute diverse teaching programs, reduce teachers' odd jods, give more financial support for discretionary activities, secure subject teachers, provide training opportunities for optional activities, exchange information on the operation of optional activities among schools, and support joint operation programs. Designs and various examples of its organization and implementation. With analyais of these results, we developed the designs of its organization and implementation method of optional activities for special schools. First, in our designs of its organization and implementation, we approached the sub-activity divisions which composed of two. the first one is optional activities of subject matters which involves the in-dept and supplementary study of therapy education activities and the in-dept and supplementary study of elective-centered subject matters. the second one is creative optional which involves integrated and self-directed study. Second, we conducted to figure out various possible methods in each sub-activities about time allotment, learning group, class time management, teaching method, teaching contents, assessment method. Third, when design of organization and implementation of optional activity, we usually use diverse optional activity examples from regular and special schools. Forth, in appendix of this book, we provided the cases of discretionary activity of regular and special schools's. So, it enables teachers to use as practice resource material, in their schools.

완전 방실차단을 동반한 급성 심근염

이유선,정진옥,박용규,박형서,노상필,정승현,김정희,이재환,최시완,성인환 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

급성 심근염환자에서 발행한 완전 방실차단을 영구 심장박동 조율기로 치료한 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Myocarditis, an inflammatory process involving the myocardal wall, may be caused by most infectious agents. Irrespective of its etiology, it presents commonly with evidence of heart failure, hypotension, and various electrocardiographic abnormalities. Patient with myocarditis may be asymptomatic or may have a rapidly progressive fatal disease. Medical management of patients with myocarditis includes specific therapy for underlying infection and control of the complication of myocarditis such as congestive heart failure and arrhythmia. Recently we had experienced myocarditis with complete atrioventricular block in 37-year-old man. Although he had shown complete recovery of heart failure, he had shown complete atrioventricular block, so we inserted permanent pacemaker. We report it with review of the literature.

한국산 시궁쥐(Rattus norvegicus)와 곰쥐(Rattus rattus)의 mtDNA RFLPs

김회숙,유선아,백상기,김영진 충남대학교 기초과학연구소 1996 忠南科學硏究誌 Vol.23 No.2

RFLPs(restriction fragment length polymorphisms) of mitochondrial DNA(mtDNA) of Rattus norvegicus and Rattus rattus in Korea were observed. All of the mtDNA of R. norvegicus individuals were shown no variatioin by the single digestion with EcoR Ⅰ, Hind Ⅲ, Ksp Ⅰ, Hind Ⅱ and Cfo Ⅰ as well as the double digestion with BamH Ⅰ/Sac Ⅰ or Hpa Ⅰ/Xba Ⅰ. Morph-1(18.75%) and morph-2(81.25%)) were observed by digestion with Hind Ⅱ in mtDNA of R. norvegicus. Morph-1(91.70%) and morph-2(8.30%) were observed by digestion with Cfo Ⅰ in mtDNA of R. norvegicus. In the mtDNA obtained from 3 R. rattus individuals, no variants were observed. The types of mtDNA obtained from 48 R. norvegicus individuals were four types(RN 1, RN 2, RN 3 and RN 4). The frequency of RN 1, RN 2, RN 3 and RN 4 was 66.67%, 14.58%, 6.25% and 12.50%, respectively. The value range of nucleotide diversity in mtDNA of R. norvegicus was between 0.0059 and 0.0153, and the value of nucleotide diversity of mtDNA between R. norvegicus and R. rattus was 0.13. The divergence time between the two species is believed to be 6.5 million years ago.