위암환자의 복강내에 투여한 Mitomycin C-Carbon Particle의 Mitomycin 용출에 관한 연구

노승무,조영훈,정경수,오정연,김진향,양준묵,강대영,송규상,조준식,최선웅,이진호,민병무,김용백,김창식,박근성,인현빈,정현용,김학용 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

Locoregional recurrence is the most common type of recurrence in surgical operation of gastric adenocarcinoma, and peritoneal dissemination is one of the most difficult problems in advanced gastric adenocarcinoma treatment. Because the peritoneal cavity is the most common site of the first recurrence after gastric cancer resection, intraperitoneal chemotherpy seems a logical choice for cancer chemotherapy. The Mitomycin C(MMC) adsorbed by the activated charcoal particles(CH) is relatively released when the drug concentration surrounding the carbon particles becomes low in the peritoneum of the peritoneal cavity. For the intraperitoneal chemotherapy on the advanced gastric adenocarcnoma, mitomycin C adsorbed on activated carbon particles was administered in the peritoneal cavity just before abdominal wall closure. The closed drainage tubes were inserted in the peritoneal cavity and clamped for tuo hours after completion of operation. MMC concentrations were serially measured in peritoneal fluid, plasma and urine at 2hour, 48 hour, 72 hour and 168 hour following its administration in order to study the efficacy of the MMC-CH as a drug delivery system. There were minimal toxicities in born marrow, liver, and gastrointestinal system after intraperitoneal MMC-CH administration. The data of this study suggested that MMC-CH may have a somewhat more beneficial effect than surgery alone when administered in optimal dose and schedules, but the MMC concentration of the peritoneal fluid was not sufficient to eradicate remnant cancer cells, and effective duration of maintenance was only below 24 hours in the peritoneal fluid and plasma.

실시간 수질 예측을 위한 신경망 모형의 적용

조용진,연인성,이재관 한국물환경학회 2004 한국물환경학회지 Vol.20 No.4

The objective of this study is to test the applicability of neural network models to forecast water quality at Naesa and Pyongchang river. Water quality data devided into rainy day and non-rainy day to find characteristics of them. The mean and maximum data of rainy day show higher than those of non-rainy day. And discharge correlate with TOC at Pyongchang river. Neural network model is trained to the correlation of discharge with water quality. As a result, it is convinced that the proposed neural network model can apply to the analysis of real time water quality monitoring.

高校生의 體格 및 運動能力 實態에 關한 硏究 : 市內 人文 實業高를 中心으로 For Liberal and Vocational Highschool Students in the City of Taegu

趙衍澈,崔容鎬 啓明大學校 生活科學硏究所 1987 科學論集 Vol.13 No.-

By the result of the research on the physical performance of three thousand eight hundred and four students-1750 liberal highschool students and 2054 vocational high school students I have the conclusion as the following. 1. The height and physical performance for each age are given in Table 4. 2. Vocational high school students have stronger physique than liberal high school students on both the pull-ups (liberal high school students; 9.27±2.50; Vocational high school students; 12.35±2.70)and the sit-ups (liberal high school students 49.32±6.44, Vocational high school students 56.53±4.41).

이상근의 연가곡 「아가ⅠᆞⅡ」의 한국적 표현에 관한 연구

조용연 민족음악학회 2005 음악과 민족 Vol.30 No.-

고등어 및 정어리 선어의 휘발성성분

조우진,김훈,정연정,이영미,정은정,차용준 창원대학교 생활과학연구소 2002 생활과학연구 Vol.- No.6

This study was conducted to identify volatile compounds, associating with quality deterioration, which may play roles as indicators for quality assessment in fresh mackerel and sardine. Volatile compounds were analyzed by liquid liquid continuous extraction(LLCE)/GC/MSD methods. A total of 83 and 81 volatile compounds were detected in fresh mackerel and sardine, respectively, and these compounds were mainly composed of aldehydes(12 in raw mackerel, 11 in raw sardine), ketones(7, 4), alcohols(15, 14), esters(1, 3), aromatic compounds(13, 15), terpenes(5, 7), S-containing compounds(2, 2), hydrocarbons(13, 11) and miscellaneous compounds(2, 1). Most of compounds including carbonyls, alcohols, aromatic compounds and hydrocarbons were derived from lipid oxidation, and some compounds were detected from microbial degradation. It was supposed that LLCE method was proper to seek indicators for quality assessment in fresh mackerel and sardine, because of various volatile compounds derived from nonthermal lipid oxidation.

急性 骨髓性 白血病 患者 1例에 對한 臨床報告

조정효,유화승,최우진,이용연,서상훈,이연월,손창규,조종관 대전대학교 한방병원 2000 惠和醫學 Vol.9 No.2

AML is the most common type of leukemia in adults. AML(acute myeloid leukaemia) is characterised by a rapid accumulation of abnormal white blood cells in the blood and bone marrow, resulting in severe anemia, and possibly infection, and hemorrhage during the course of the disease. In general the prognosis of patient with relapsed AML is poor. At this time, however, the only potentially curative therapy for relapsed patients is allogeneic BMT(bone marrow transplantation). This clinical study were carried out 1 case of female patient aged 44 with relapsed AML treated by herb medicine. At the time of admission, she complained of mild fever, nausea, vomitting, abdominal pain, anorexia and no sign of bleeding. For the 10 days of admission, she was treated with Oriental-Western medicine and all the symptoms were disappeared. After that, the syptoms were aggravated because of secondary infection. Anyway, above result showed the possibility of Oriental therapy as Supportive Care in AML.

용혈성 빈혈과 흑수열을 동반한 Chloroquine저항성 수입 열대열 말라리아 1예

조희충,국기용,박일,최연수,이승일 조선대학교 1994 The Medical Journal of Chosun University Vol.19 No.1

저자들은 최근 아프리카를 여행하는 도중 말라리아의 예방약제인 chloroquine을 복용하였음에도 불구하고 용혈성 빈혈과 흑수열을 동반한 chloroquine 저항성 수입 열대열 말라리아를 Fansidar를 투여하여 치료가 된 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. This previously healthy 26 year-old student was admitted to Cho Sun university hospital due to paroxysmal high fever, dizziness of 2 weeks duration and he also noted passage of dark brownish colored urine of 3 days duration. He had made journey to Africa for 2 months before admission. He had taken chloroquine 1 week before his jurney and continued this weekly throughout his stay. On admission, there was fever of 38.5℃ and numerous parasitemia of ring form of P. falciparum in the peripheral blood smear. On physical examination, he had jaundice and splenomgaly. On laboratory examination, he had jaundice and splenomegaly. On laboratory examination hemoglobin was 5.Og / dl, reticulocytecount was 11%, plasma hemoglobin was 7.5mg /dl and urine hemoglobin was 2.5mg /dl. He received Fansidar on 2nd day of admission. Five days later, his blood was completely clear of parasite and 7th day after admission, all symptoms were almost improved and then he was discharged.

급성세균성전립선염의 임상적 특징 및 치료 결과

조수연,배웅진,조용현,이승주 대한감염학회 2009 감염과 화학요법 Vol.41 No.1

Background : Acute bacterial prostatitis is an uncommon male urinary tract infection that is the result of severe prostatic infection mainly by gram-negative bacteria. We conducted a retrospective study to report clinical outcomes of patients with acute bacterial prostatitis. Materials and Methods : The clinical records of 49 patients diagnosed with acute bacterial prostatitis were reviewed retrospectively and patients' symptoms, investigations, and treatments were analyzed. Results : All patients presented with fever and voiding symptoms. Some patients (22.4%) had a history of prior manipulation of the lower urinary tract including transrectal prostate biopsy. Urine cultures were positive for 51% of the patients. The most common pathogen was Escherichia coli (60%), followed by Pseudomonas aeruginosa (20%) and Staphylococcus aureus (12%). The ciprofloxacin susceptibility against E. coli was 80%. All patients were treated with parenteral antibiotics in the hospital followed by oral antibiotics for average of three weeks. The major drugs used for empirical treatment were cephalosporins, aminoglycosides, and fluoroquinolones. Prostatic abscess was found in two (4.1%) Patients and chronic pelvic pain syndrome developed in six (12.2%) patients during follow-up. Conclusion : The currently used empirical antibiotics were mostly effective in the treatment of acute bacterial prostatitis. Continuous monitoring on antimicrobial susceptibility of acute bacterial prostatitis was necessary for providing proper treatment guideline.

기종성 신우신염의 임상양상 및 사망위험인자

조수연,이호재,조용현,이승주 대한감염학회 2009 감염과 화학요법 Vol.41 No.1

Background : Emphysematous pyelonephritis (EPN) is an acute gas forming necrotizing infection of the renal parenchyma with high mortality. Although its incidence is relatively low, it mostly occurs in patients wiith diabetes mellitus. The aim of the study is to identify the risk factors related to mortality and assess the outcome of managements according to the radiologic classification. Materials and Methods : The clinical records of 23 patients diagnosed with EPN were reviewed retrospectively. The cases were grouped into two types on the basis of computed tomography scan. Type 1 EPN was defined as renal necrosis and gas formation with total absence of fluid content. Type 2 EPN was defined as the presence of renal or perirenal fluid in association with bubbly or loculated gas pattern. The patients' symptoms, performed investigations, and treatments were analyzed. Results : All patients had diabetes mellitus. Escherichia coli (78.6%) was the most common pathoqen in urine and blood cultures. The factors showing statistically significant differences between survivors and non-survivors were age (P=0.013), the presence of obstructive uropathy (P= 0.008), and type 1 group (P=0.030). Multivariate logistic regression showed that factor significantly related to death was age (odds ratio=1.20, 95% confidence interval 1.01-1.38, P=0.037). Conservative treatment including antibiotics and percutaneous drainage was successful in type 2 group, Overall mortality was 26.1%; all expired patients were from type 1 group. The mortality of conservative treatment and nephrectomy in type 1 group was 83.3% and 20.0%, respectively. Conclusion : These results suggest that old age is a significant risk factor for mortality in patients with EPN. Nephrectomy should be considered as the main treatment option in patients with type 1 EPN.

중국 체육행정 조직관리의 이론적 고찰

조연철,임용호 啓明大學校 生活科學硏究所 1997 科學論集 Vol.23 No.-

In these days, an open-door policy and the market economy of China have an effect on development of the all chinese society, and bring on changes in many fields- politics, economy, culture, and so on. Thus, the administative oganization of physical education on centralizing system based on existing planned economy system is changing. The system of the existing administative oganizationth of physical education is divided by the management system of government and community. The management system of government for administative oganization of physical education is still characteristic of centralizing system carried out main projects of physical education. There is many changes as result of system reformation to achieve the proper management system of administative oganization of physical education for the market economy. The management of centralizing system is weakened, and the self-control of the management system of community improve, that is, the macroscopic management funtion of government and microscopic management funtion of community is stregthened.