내시경적 점막절제술로 치험한 식도 과립상 세포종 1례

강혁주,김성욱,최석진,이중현,장재식,서영범,윤병구,박건욱,김성자,김용섭,강승완,이구,양창헌,이창우,김욱년,이광헌,서정일 동국대학교 의학연구소 2000 東國醫學 Vol.7 No.-

과립상 세포종은 Schwann 세포 기원으로 생각되며 인체에 비교적 드물게 발생한다. 과립상 세포종은 전신 어느 곳에서나 발견될 수 있으나 주로 혀, 구강, 피부 혹은 유방 등에서 호발하며 드물게 위장관에서 발견된다. 위장관에서는 식도에서 가장 호발하며 다음으로 위, 대장 순이다. 과립상 세포종은 대부분, 특히 위장관에서는 양성이며 소수의 악성 병변이 보고되었다. 이러한 이유와 함께 수술 전의 진단이 어렵기 때문에 과립상 세포종에 대한 근본적인 치료는 현재까지 외과적 절제술이다. 최근에 시도되는 치료방법들로는 내시경적 레이저 치료, 용종절제술, 내시경적 점막 절제술 등이 있다. 저자들은 상부 소화관 내시경검사를 시행하여 식도 과립상 세포종을 진단하고 내시경적 점막 절제술을 시행하여 합병증 없이 퇴원하여 현재 재발없이 경과 관찰중인 1례를 경험하였기에 보고하는 바이다. Granular cell tumors, which occur infrequently, are probably of Schwann cell origin. They can occur almost anywhere in the body but usually affect the tongue, oral cavity, skin, or breasts and are rarely found in the gastrointestinal tracts. The esophagus is the most frequent gastrointestinal site, followed by the stomach and the colon. Granular cell tumors are generally benign, especially in the gastrointestinal tract, some malignant lesions have been reported. For this reason, and also because preoperative diagnosis is difficult, the standard treatment for granular cell tumor has until now been surgical excision. In recent years, other therapeutic methods is endoscopic laser therapy (ELT), polypectiomy, endoscopic mucosal resection (EMR). We report a case of esophageal granular cell tumor which was diagnosed by an endoscopy and managed using an endoscopic mucosal resection without complication.

한국 정신장애의 역학 조사 연구[I] : 각 정신장애의 유병률

조맹제,함봉진,김장규,박강규,정은기,서동우,김선욱,조성진,이준영,홍진표,최용성,박종익,이동우,이기철,배재남,신정호,정인원,박종한,배안,이충경 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.4

Objectives : This study aims to estimate the prevalence of the DSM-IV psychiatric disorders in Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI). Methods : Subjects were selected by taking multi-stage, cluster samples of 7,867 adult household residents, 18 to 64 years of age, in ten catchment areas. Total 78 trained interviewers administered the K-CIDI to the selected respondents, from June 1 to November30,2001. Results : Total 6,275 respondents completed the interview. Some 33.5% of respondents reported at least one lifetime disorder, 20.6% reported at least one-year disorder, and 16.7% reported at least one-month disorder. The most common lifetime disorders were alcohol abuse/dependence (17.24%), nicotine dependence/withdrawal (11.19%), specific phobia (5.16%), and major de-pressive disorder (4.25%). The lifetime prevalence of substance abuse/dependence (0.25%) and schizophrenia (0.16%) was very low. Nicotine and alcohol use disorder showed very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among female than male. Conclusion : The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in distributions of psychiatric disorders across the areas and times were observed.

지난 4년간 학회지 "신경정신의학" 심사 평가보고

오병훈,권준수,남궁기,김승현,지익성,김창윤,하규섭,박원명,김성곤,오강섭,김정범,이수정,정한용,이창욱,박용천,이영문,김세주,이병욱 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.5

Four Years Reports of "Journal of Korean Neuropsychiatric Association" during 2001 to 2005 were evaluated by 18 Editorial Board of Korean Neuropsychiatric Association. We investigated the articles to specific fields and rejection rate etc. by different section chiefs. Although several problems concerning review time duration and rejection guideline issues indicated but generally all reviewer processes proved relatively clear and concise criteria. Through these objective and systematic evaluation Processes, "Journal of Korean Neuropsychiatric Association" will develop a good journal.

TFSCAN 검색 프로그램 TFSCAN의 개발

이병욱,박기정,김기봉,박완,박용하 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.3

TFD는 기능이 알려진 짧은 DNA sequence(signal)들과 그와 연관된 저널 자료로 구성된 데이타베이스이다. 임의의 DNA에서 이 데이타베이스의 sequence들을 검색하여 signal을 찾는 프로그램으로 Dan S. Prestridge가 개발한 SIGNAL SCAN이라는 프로그램이 사용되고 있는데, 이는 간단한 문자열 비교 알고리즘을 사용한다. 본 연구에서는 계산상 보다 효율적인 검색을 위해서, TFD의 sequence를 검색하기 위한 automata를 구성하는 프로그램과, 이 automata에 따라 signal을 검색하도록 하는 TFSCAN이라는 프로그램을 개발하였다. 검색된 signal에 대한 관련 문헌의 검색에서도 인덱싱 방법을 이용하여 계산 속도를 향상시켰다. 프로그램의 사용을 단순화시켰고, 결과 내용을 signal과 관련된 모든 정보를 일목요연하게 보여줄 수 있도록 구성하였다. 이 프로그램을 Web을 통해서도 사용할 수 있도록, GINet Web 서버에 TFSCAN 입력용 form과 CGI 프로그램을 개발·설치하였다. 본 연구의 특정 Motif 패턴으로 구성된 데이타베이스 검색에서, automata를 응용한 알고리즘을 이용하여 계산상 급격히 향상된 결과를 얻을 수 있음을 알 수 있었는데, 이는 생물학의 여러 패턴 검색에 응용될 수 있을 것이다. 더욱 민감한(sensitive) signal 검색을 위해서, 이와 같이 automata를 활용하고, 이 automata를 최적화하는 알고리즘 연구를 계속하고 있다. TFD is a transcription factor database which consists of short functional DNA sequences called as signals and their references. SIGNAL SCAN, developed by Dan S. Prestridge, is used to determine what signals of TFD may exist in a DNA sequence. This program searches TFD database by using a simple algorithm for character string comparison. We developed TFSCAN that aims at searching for signals in an input DNA sequence more efficently than SIGNAL SCAN. Our algorithms consist of two parts, one constructs an automata by scanning sequences of TFD, the other searches for signals through this automata. Searching for signal-related references is radically improved in time by using an indexing method. Usage of TFSCAN is very simple and its output is obvious. We developed and installed a TFSCAN input form and a CGI program in GINet Web server, to use TFSCAN. The algorithm applying automata showed drastical results in improvement of computing time. This approach may apply to recognizing several biological patterns. We have been developing our algorithm to optimize the automata and to search more sensitively for signals.

周邊情勢와 南北韓關係 展望

李一洙,金容郁 군산대학교 현대이념연구소 1997 現代理念硏究 Vol.12 No.-

비대칭 경로를 지원하는 개선된 DSR 라우팅에 관한 연구

이광배,김현욱,곽승욱,박용정 명지대학교 산업기술연구소 2001 産業技術硏究所論文集 Vol.20 No.-

This paper introduces a dynamic source routing protocol supporting asymmetric routes on mobile ad hoc network. For performance evaluation, average route discovery time, average data transfer time, average route recovery time and data reception rate were considered with several scenarios relating to connection pattern, moving scenario, usage of secondary route chche in intermediate nodes and periodic hello message interval. As the results, we found that the data reception rate increased as the node mobility went down and the number of maximum connections between nodes was reduced. In the case that secondary route cache was used in the intermediate nodes, the average data transfer time was decreased because the possibility of route discovery to destination node was increased. In addition, it was found that the hello message interval at 0.1 to 1 second was fairly good.

음경에 발생한 기저세포암 1예

이용주,최혜자,윤석권,김한욱,임철완 대한피부과학회 2004 大韓皮膚科學會誌 Vol.42 No.3

Basal cell carcinoma is the most common malignant skin cancer in Korea. The lesions are most frequently found in the head and neck region. But penile basal cell carcinoma is very rare and there are only 29 other reported cases. We report a rare case of basal cell carcinoma of the penis in a 76-year-old man. He had a well circumscribed 1.3㎝×1.3㎝ thick scaly plaque with central ulcer in right penile root area for 4 years. The lesion was completely excised and no recurrence for four months. (Korean J Dermatol 2004;42(3):350~352)

朝鮮前期 歌辭에 나타난 自然의 表現 : 바다와 河川을 中心으로

이용욱 동아대학교 국어국문학과 1985 국어국문학 Vol.6 No.-

구내신연장치를 이용한 치조골증대술 후 임프란트 매식 : 치험 5예 REPORT OF 5 CASES

이용욱,박충열,송종운,박홍주,김영운,오희균,유선열 대한악안면성형재건외과학회 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.2

Successful alveolar ridge augmentation by distraction osteogenesis method has been reported previously. There are several types of devices for alveolar ridge augmentation. In this paper, a new intraoral distraction device was used on the severe atrophic mandible in order to distract an alveolar ridge vertically in 5 patients. Mean amount of distracted alveolar ridge was 7.4㎜ (5∼9.5㎜). Dental implants were placed in the distracted alveolar bone and good osseointegration was obtained in all patients. Mean follow up period is 2years 6months (7months∼4years 9months). No complications, such as infection or resorption was observed in all patients. Alveolar ridge augmentation by gradual distraction seems to be a safe, simple and reliable procedure.

「不完全競爭理論의 基本命題」에 대한 검토

李容旭 대구 효성가톨릭대학교 1969 연구논문집 Vol.5 No.1