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Suzhen Wang,Jianbin Li,Yingjie Zhang,Wei Wang,Fengxiang Li,Tingyong Fan,Min Xu,Qian Shao 대한영상의학회 2012 Korean Journal of Radiology Vol.13 No.4
Objective: To measure the intra-fraction displacements of the mediastinal metastatic lymph nodes by using four-dimensional CT (4D-CT) in non-small cell lung cancer (NSCLC). Materials and Methods: Twenty-four patients with NSCLC, who were to be treated by using three dimensional conformal radiation therapy (3D-CRT), underwent a 4D-CT simulation during free breathing. The mediastinal metastatic lymph nodes were delineated on the CT images of 10 phases of the breath cycle. The lymph nodes were grouped as the upper, middle and lower mediastinal groups depending on the mediastinal regions. The displacements of the center of the lymph node in the left-right (LR), anterior-posterior (AP), and superior-inferior (SI) directions were measured. Results: The mean displacements of the center of the mediastinal lymph node in the LR, AP, and SI directions were 2.24 mm, 1.87 mm, and 3.28 mm, respectively. There were statistically significant differences between the displacements in the SI and LR, and the SI and AP directions (p < 0.05). For the middle and lower mediastinal lymph nodes, the displacement difference between the AP and SI was statistically significant (p = 0.005; p = 0.015), while there was no significant difference between the LR and AP directions (p < 0.05). Conclusion: The metastatic mediastinal lymph node movements are different in the LR, AP, and SI directions in patients with NSCLC, particularly for the middle and lower mediastinal lymph nodes. The spatial non-uniform margins should be considered for the metastatic mediastinal lymph nodes in involved-field radiotherapy. Objective: To measure the intra-fraction displacements of the mediastinal metastatic lymph nodes by using four-dimensional CT (4D-CT) in non-small cell lung cancer (NSCLC). Materials and Methods: Twenty-four patients with NSCLC, who were to be treated by using three dimensional conformal radiation therapy (3D-CRT), underwent a 4D-CT simulation during free breathing. The mediastinal metastatic lymph nodes were delineated on the CT images of 10 phases of the breath cycle. The lymph nodes were grouped as the upper, middle and lower mediastinal groups depending on the mediastinal regions. The displacements of the center of the lymph node in the left-right (LR), anterior-posterior (AP), and superior-inferior (SI) directions were measured. Results: The mean displacements of the center of the mediastinal lymph node in the LR, AP, and SI directions were 2.24 mm, 1.87 mm, and 3.28 mm, respectively. There were statistically significant differences between the displacements in the SI and LR, and the SI and AP directions (p < 0.05). For the middle and lower mediastinal lymph nodes, the displacement difference between the AP and SI was statistically significant (p = 0.005; p = 0.015), while there was no significant difference between the LR and AP directions (p < 0.05). Conclusion: The metastatic mediastinal lymph node movements are different in the LR, AP, and SI directions in patients with NSCLC, particularly for the middle and lower mediastinal lymph nodes. The spatial non-uniform margins should be considered for the metastatic mediastinal lymph nodes in involved-field radiotherapy.
Xiaohong Wang,Zhen Wang,Yingjie Fan,Jianwei Xia,Hao Shen 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.4
This paper addresses the global asymptotic stabilization of delayed fractional complex-valued neural networks(FCVNNs) subject to bounded parameter uncertainty. The problem is proposed for two reasons: 1) The availablemethods for uncertain dynamical systems may be too conservative; 2) The existing algebraic conditions willlead to huge computational burden for large-scale FCVNNs. To surmount these difficulties, the delayed FCVNNswith interval parameters are transformed into a tractable form at first. Then, a simple and practical controller–linearstate feedback controller is designed to achieve the global asymptotic stabilization. By constructing different Lyapunovfunctions and utilizing the fractional-order comparison principle and interval matrix method, two sufficientglobal asymptotic stabilization criteria expressed in LMI forms, are established. The obtained results in this paperimprove and extend some previous published results on FCVNNs. Finally, two numerical examples are provided toillustrate the correctness of the theoretical results.
Evaluation of Tunnel Face Stability Subjected to Seismic Load Based on the Non-associated Flow Rule
Qiguang Di,Pengfei Li,Mingju Zhang,Caixia Guo,Fan Wang,Yingjie Wei 대한토목학회 2022 KSCE Journal of Civil Engineering Vol.26 No.5
Reasonable determination of the stability of the tunnel face under complex conditions is necessary for safe construction. This paper focuses on the seismic stability of the tunnel face in cohesion-frictional soils based on the non-associated flow rule. The pseudo-static approach is adopted to reflect the seismic effect. An analytical model is proposed based on the limit analysis method. A series of numerical simulations are performed to verify the rationality of the theoretical model. Then, parametric analyses are carried out. Results show that the proposed model is reasonable to investigate the tunnel face stability under the seismic load. The study indicates that it is essential to consider not only the seismic load but also the non-associated flow rule when determining the limit support pressure of tunnel face, especially in the soils with high friction angle or unit weight.
Wang Rongxi,Yu Xiaoyue,Wang Zhiqiang,Liu Yujie,Chen Hui,Liu Shangbin,XU CHENG,Chen Yingjie,Xia Danni,Ge Xin,Chang Ruijie,Xu Gang,Xiang Mi,Wang Ying,Shen Tian,Hu Fan,Cai Yong 한국역학회 2022 Epidemiology and Health Vol.44 No.-
OBJECTIVES: Proper blood lipid levels are essential for survival in older adults, but inconsistent relationships have been reported between blood lipids and all-cause mortality in the elderly. METHODS: This retrospective longitudinal study analyzed data from 1,067 Chinese older adults enrolled in the Chinese Longitudinal Healthy Longevity Survey collected in 2008 and followed up until death or December 31, 2018. The outcome was allcause mortality. Multivariate Cox regression analyses were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) with stratification by age (60-80, 80-100, or ≥ 100 years) for further analysis. The survival probability according to lipid profile quartiles was calculated using Kaplan-Meier curves and the log-rank test. RESULTS: The participants’ mean age was 84.84 years, and 57.0% were female. In total, 578 individuals died, and 277 were lost to follow-up. The mean total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) levels were higher among those who died than among those who survived. Participants in the second HDL-C quartile and the highest LDL-C and triglyceride (TG) quartiles had 28% higher, 23% lower, and 49% lower risks of all-cause mortality, respectively. After further adjustment, the associations remained except for HDL-C, and additional associations were observed between all-cause mortality and the third TC and LDL-C quartiles and the second TG quartile (HR, 1.44; 95% CI, 1.01 to 2.06; HR, 0.68; 95% CI, 0.49 to 0.94; HR, 0.79; 95% CI, 0.62 to 0.99, respectively). CONCLUSIONS: Older adults should maintain an LDL-C level of 1.91-2.47 mmol/L and a TG level of no less than 1.66 mmol/L.