Uniaxial Eccentric Load Behavior of L-CFSST Composite Column

Zhen Wang,Zhe Liu,Xingbo Wang,Xuejun Zhou,Zhoutai Wang,Guodong Xian 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.5

This study presents the mechanical behavior of L-shaped concrete-filled square steel tube (L-CFSST) composite columns under uniaxial eccentric compression. Nine specimens were tested and the effects of eccentricity, steel tube thickness, steel yield strength, and slenderness ratio were investigated regarding failure modes, ultimate load, load-lateral displacement curves, and load-strain curves. Test results showed that, under uniaxial eccentric load, these columns showed favorable mechanical properties and steel tubes showed strong cooperative working performance. There were two types of failure modes for these columns: local buckling of the steel tube or overall bending of the specimen. ABAQUS was used to simulate the loading process and the accuracy of the numerical simulation results was verified by comparing failure characteristics, load-displacement curves, and ultimate bearing capacity with the test results. The N/Nu-M/Mu curves of the columns under uniaxial eccentric load with different parameters were simulated by the finite element method. A simplified formula for predicting the N/Nu-M/Mu relationship was established based on the finite element analysis results, which might be a workable approach for designing L-CFSST composite columns in engineering practice.

The prognostic and predictive value of plasma D-dimer in children with neuroblastoma: a 7-year retrospective analysis at a single institution

Zhen-Ni Wang,Yao Zhang,Jian Sun,Zhen-Zhen Zhao,Shan Wang,Chao Yang 대한외과학회 2023 Annals of Surgical Treatment and Research(ASRT) Vol.105 No.3

Overexpression of a peroxiredoxin gene from Tamarix hispida, ThPrx1, confers tolerance to oxidative stress in yeast and Arabidopsis

Liuqiang Wang,Zhen Li,Chao Wang,Deyin Wang,Yucheng Wang,Mengzhu Lu 한국식물학회 2017 Journal of Plant Biology Vol.60 No.6

Peroxiredoxins (Prxs) are ubiquitous thiol-specificantioxidant enzymes that are critically involved in cell defenseand protect cells from oxidative damage. In this study, aputative Type II Prx (ThPrx1) was identified and characterizedfrom Tamarix hispida. The expression of ThPrx1 is highlyinduced in response to hydrogen peroxide (H2O2) and methylviologen (MV) stresses. When expressed ectopically, ThPrx1showed enhanced tolerance against oxidative stress in yeastand Arabidopsis. In addition, transgenic Arabidopsis plantsoverexpressing ThPrx1 displayed improved seedling survivalrates and increased root growth and fresh weight gain underH2O2 and MV treatments. Moreover, transgenic Arabidopsisplants showed decreased accumulation of H2O2, superoxide(O2•−) and malondialdehyde (MDA), increased superoxidedismutase (SOD) activity compared to wild-type (WT) plantsunder oxidative stress. Moreover, transgenic plants maintainedhigher photosynthesis efficiency and lower electrolyte leakagerates than that of WT plants under stress conditions. Theseresults clearly indicated that ThPrx1 plays an important rolein cellular redox homeostasis under stress conditions, leadingto the maintenance of membrane integrity and increasedtolerance to oxidative stress.

Inhibitory effects of piceatannol on human cytomegalovirus (hCMV) in vitro

Wang San-Ying,Zhang Jing,Xu Xiao-Gang,Su Hui-Li,Xing Wen-Min,Zhang Zhong-Shan,Jin Wei-Hua,Dai Ji-Huan,Wang Ya-Zhen,He Xin-Yue,Sun Chuan,Yan Jing,Mao Gen-Xiang 한국미생물학회 2020 The journal of microbiology Vol.58 No.8

Human cytomegalovirus (hCMV) is a ubiquitous herpesvirus, which results in the establishment of a latent infection that persists throughout the life of the host and can be reactivated when the immunity is low. Currently, there is no vaccine for hCMV infection, and the licensed antiviral drugs mainly target the viral enzymes and have obvious adverse reactions. Thus, it is important to search for compounds with antihCMV properties. The present study aimed to investigate the suppressive effects of piceatannol on hCMV Towne strain infection and the putative underlying mechanisms using human diploid fibroblast WI-38 cells. Piceatannol supplementation prevented the lytic changes induced by hCMV infection in WI-38 cells. Furthermore, piceatannol suppressed the expression of hCMV immediate-early (IE) and early (E) proteins as well as the replication of hCMV DNA in a dose-dependent manner. Moreover, hCMV-induced cellular senescence was suppressed by piceatannol, as shown by a decline in the senescence-associated β-galactosidase (SA-β-Gal) activity and decreased production of intracellular reactive oxygen species (ROS). p16INK4a, a major senescence-associated molecule, was dramatically elevated by current hCMV infection that was attenuated by pre-incubation with piceatannol in a dose-dependent manner. These results demonstrated that piceatannol suppressed the hCMV infection via inhibition of the activation of p16INK4a and cellular senescence induced by hCMV. Together, these findings indicate piceatannol as a novel and potent anti-hCMV agent with the potential to be developed as an effective treatment for chronic hCMV infection.

Repeat Colonoscopy Every 10 Years or Single Colonoscopy for Colorectal Neoplasm Screening in Average-risk Chinese: A Cost-effectiveness Analysis

Wang, Zhen-Hua,Gao, Qin-Yan,Fang, Jing-Yuan Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.5

Background: The appropriate interval between negative colonoscopy screenings is uncertain, but the numbers of advanced neoplasms 10 years after a negative result are generally low. We aimed to evaluate the cost-effectiveness of colorectal neoplasm screening and management based on repeat screening colonoscopy every 10 years or single colonoscopy, compared with no screening in the general population. Methods and materials: A state-transition Markov model simulated 100,000 individuals aged 50-80 years accepting repeat screening colonoscopy every 10 years or single colonoscopy, offered to every subject. Colorectal adenomas found during colonoscopy were removed by polypectomy, and the subjects were followed with surveillance every three years. For subjects with a normal result, colonoscopy was resumed within ten years in the repeat screening strategy. In single screening strategy, screening process was terminated. Direct costs such as screening tests, cancer treatment and costs of complications were included. Indirect costs were excluded from the model. The incremental cost-effectiveness ratio was used to evaluate the cost-effectiveness of the different screening strategies. Results: Assuming a first-time compliance rate of 90%, repeat screening colonoscopy and single colonoscopy can reduce the incidence of colorectal cancer by 65.8% and 67.2% respectively. The incremental cost-effectiveness ratio for single colonoscopy (49 Renminbi Yuan [RMB]) was much lower than that for repeat screening colonoscopy (474 RMB). Single colonoscopy was a more cost-effective strategy, which was not sensitive to the compliance rate of colonoscopy and the cost of advanced colorectal cancer. Conclusion: Single colonoscopy is suggested to be the more cost-effective strategy for screening and management of colorectal neoplasms and may be recommended in China clinical practice.

Application of Building Block Approach on Crashworthiness Design of Composite Vehicular Structures

Zhen Wang,Kai Song 한국섬유공학회 2022 Fibers and polymers Vol.23 No.6

Firstly, the representative volume element (RVE) model was established at the microscale, a three-dimensionalmicromechanical material constitutive relationship was defined as the user defined material subroutine (UMAT) inABAQUS/Standard, which was able to accurately capture mechanical behaviors of both matrix and fiber materials. Constrained by periodic boundary conditions (PBCs), the RVE model can be used to predict elastic properties as well asstrength properties of the composite laminates. Then, the accuracy of the RVE model was validated by comparing the tensileresponses between predictions and experiments. Next, comparisons in the flexural responses of carbon fiber reinforcedplastic (CFRP) laminates, lateral and axial crushing behaviors of CFRP tubes between single-layer and multi-layer modelingapproaches were investigated at the mesoscale, respectively. Numerical results indicated that the single-layer model wasefficient to predict the mechanical indictors while the multi-layer method can reliably predict both mechanical indictors anddeformation patterns. Finally, the validated finite element model (FEM) and material constitutive model were employed toinvestigate the material cost and crashworthiness characteristics of the composite bumper subsystem of the electric vehicleunder the frontal crash condition at the macroscale.

Robust Secure UAV Relay-Assisted Cognitive Communications with Resource Allocation and Cooperative Jamming

Zhen Wang,Jichang Guo,Zhiqiong Chen,Zhiqiong Chen,Lisu Yu,Yuhao Wang,Hong Rao 한국통신학회 2022 Journal of communications and networks Vol.24 No.2

This paper considers a novel scenario, where a physicallayer security issue is studied in unmanned aerial vehicles(UAVs)-assisted cognitive relay system. A secondary unmannedaerial vehicle (SUAV) relay delivers information from multiplesecondary Internet of things (IoT) devices to a secondary user(SU) under the spectrum sharing with primary users (PUs). Inthe processing of the information transmission of the SUAV relay,a secondary eavesdropper (SE) wiretaps the information transmittedby the UAV relay with imperfect location information. Inorder to confuse the SE, a friendly SUAV jammer is employedto transmit jamming signals to the SE. To prevent the SEwiretapping information as much as possible, we aim to maximizeaverage worst-case secrecy rate of the secondary relay networkby jointly optimizing robust trajectories and power of the SUAVrelay and jammer under the power, trajectories, informationcausality and multiple interference temperature (IT) thresholdconstraints. Thus, we formulate the original problem whichis a challenging non-convex problem. We propose an effectivealgorithm to solve the original problem and attain locally optimalsolution based on the successive convex approximation (SCA)technology and the alternate optimization method. Simulationsare offered to demonstrate that our proposed resource allocationscheme can effectively improve the security performance ofthe SUAV relay network in comparison with other benchmarkschemes.

Sexual dimorphism-related gene expression analysis based on the transcriptome in Gynaephora qinghaiensis, a pest of grassland on the Qinghai-Tibet Plateau

Wang Hai-Zhen,Zhang Ru-yi,Yuyu-Li,Liu Xin 한국응용곤충학회 2023 Journal of Asia-Pacific Entomology Vol.26 No.2

Gynaephora qinghaiensis is a pest in the alpine meadows of the Qinghai-Tibet Plateau (QTP) that seriously harms grassland vegetation. Sexual dimorphism (SD) is common in insects, but its molecular mechanism at the tran scriptome level in insects, especially in G. qinghaiensis, has not been reported. In this study, we conducted transcriptome analysis of pupae and adults of the two sexes (male and female) of G. qinghaiensis. A total of 204,557,900 clean reads assembled into 114,944 unigenes were obtained by RNA-Seq. To explore differences in the transcriptome levels of molecular characteristics related to SD between the two sexes of G. qinghaiensis, gene expression profiling was performed. A total of 88 differentially expressed unigenes related to sex determination were found in the pupae of G. qinghaiensis; of these, 74 were upregulated and 14 were downregulated in the female pupae compared to the male pupae. Forty-five unigenes related to sex determination were found in the adults of G. qinghaiensis; of these, 15 were upregulated and 30 were downregulated in the female adults compared to the male adults. This indicated some differences in the expression of genes involved in sex deter mination between male and female individuals of G. qinghaiensis. Therefore, we speculated that sex-determining genes may play an important role in the formation of sexual dimorphism in G. qinghaiensis. Our report provides a valuable genomic resource for further studies of grassland caterpillars and improves our understanding of the molecular mechanisms underlying sexual dimorphism between male and female insects.

Adsorption of Lead(II) from Aqueous Solution by Two Modified Porous Chelating Resins Based on (3-Mercaptopropyl) Trimethoxysilane

Zhen-Zheng Wang,Hong-Dong Duan,Xia Meng,Yi-Fan Zhang,Hui-Min Qi 한국고분자학회 2016 Macromolecular Research Vol.24 No.9

Two novel types of thiol-based chelating resins were fabricated by modifying poly(2-hydroxyethyl methacrylate- co-glycerol dimethacrylate) (P(HEMA-GDMA)) and poly(2-hydroxyethyl methacrylate-co-ethylene glycol dimethacrylate) (P(HEMA-EGDMA)) with (3-mercaptopropyl) trimethoxysilane(MPS), and used to adsorb lead(II) from aqueous solution. The effects of initial lead(II) concentrations, solution pH, coexisting ions on adsorption of lead(II) were investigated. After modifying, the product P(HEMA-GDMA)-SH has excellent adsorption capacity (118.56 mg/g) for lead(II) at initial lead(II) concentration of 200 mg/L. The resins could easily be regenerated and were reused 6 times without significant loss of adsorption capacity. Besides, the presence of coexisting ions did not markedly influence the adsorption capacities of the resins. The results indicate that the functional thiol-based resins are efficient adsorbents for the removal of toxic lead(II) ions in water treatment.

Preparation and characterization of flaky FeSiAl composite magnetic powder core coated with MnZn ferrite

Zhen Wang,Xiansong Liu,Xucai Kan,Ruiwei Zhu,Wei Yang,Qiuyue Wu,Shengqiang Zhou 한국물리학회 2019 Current Applied Physics Vol.19 No.8

The flattening of FeSiAl soft magnetic powder was achieved by ball milling process, and MnZn/FeSiAl composite magnetic powder core was prepared by press molding. The effect of different coating amount of MnZn ferrite on the soft magnetic properties of FeSiAl was studied. At the same time, the optimal stress-relieving annealing temperature of the composite magnetic powder core is revealed. The results showed that the addition of MnZn ferrite affected the magnetic properties such as saturation magnetization (Ms), initial permeability (μi) and power loss (Pcm) of FeSiAl soft magnetic. With the increase of MnZn ferrite addition content, the saturation magnetization of composites decreased gradually, and the magnetic permeability increased first and then decreased, and the loss decreased first and then increased. When the addition content of MnZn ferrite was 5%, the permeability reached the maximum, which was 28.1% higher than that of the pure FeSiAl magnetic powder core under the same conditions. At the same time, the loss was the lowest, which was 13.3% lower than the pure FeSiAl powder core under the same conditions. When the annealing temperature is around 650 °C, the magnetic powder core has the largest magnetic permeability and the lowest loss.